Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HJ77_LEIBR

TriTrypDb:

LbrM.31.1170 , LBRM2903_310019500

Length:

469

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HJ77

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HJ77

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	284	288	PF00656	0.649
CLV_C14_Caspase3-7	357	361	PF00656	0.579
CLV_C14_Caspase3-7	452	456	PF00656	0.631
CLV_NRD_NRD_1	191	193	PF00675	0.626
CLV_NRD_NRD_1	339	341	PF00675	0.621
CLV_NRD_NRD_1	349	351	PF00675	0.618
CLV_NRD_NRD_1	68	70	PF00675	0.466
CLV_PCSK_KEX2_1	159	161	PF00082	0.703
CLV_PCSK_KEX2_1	191	193	PF00082	0.626
CLV_PCSK_KEX2_1	216	218	PF00082	0.679
CLV_PCSK_KEX2_1	348	350	PF00082	0.621
CLV_PCSK_PC1ET2_1	159	161	PF00082	0.703
CLV_PCSK_PC1ET2_1	216	218	PF00082	0.679
CLV_PCSK_PC1ET2_1	348	350	PF00082	0.621
CLV_PCSK_SKI1_1	217	221	PF00082	0.589
CLV_PCSK_SKI1_1	58	62	PF00082	0.591
DOC_CYCLIN_yCln2_LP_2	77	83	PF00134	0.588
DOC_USP7_MATH_1	125	129	PF00917	0.710
DOC_USP7_MATH_1	139	143	PF00917	0.530
DOC_USP7_MATH_1	15	19	PF00917	0.531
DOC_USP7_MATH_1	154	158	PF00917	0.560
DOC_USP7_MATH_1	180	184	PF00917	0.653
DOC_USP7_MATH_1	221	225	PF00917	0.752
DOC_USP7_MATH_1	28	32	PF00917	0.607
DOC_USP7_MATH_1	330	334	PF00917	0.540
DOC_USP7_MATH_1	416	420	PF00917	0.595
DOC_USP7_MATH_1	88	92	PF00917	0.544
DOC_WW_Pin1_4	115	120	PF00397	0.677
DOC_WW_Pin1_4	219	224	PF00397	0.751
DOC_WW_Pin1_4	397	402	PF00397	0.603
DOC_WW_Pin1_4	403	408	PF00397	0.561
DOC_WW_Pin1_4	8	13	PF00397	0.652
DOC_WW_Pin1_4	91	96	PF00397	0.629
LIG_14-3-3_CanoR_1	105	115	PF00244	0.627
LIG_14-3-3_CanoR_1	160	168	PF00244	0.681
LIG_14-3-3_CanoR_1	205	213	PF00244	0.656
LIG_14-3-3_CanoR_1	418	426	PF00244	0.623
LIG_14-3-3_CanoR_1	441	451	PF00244	0.543
LIG_BIR_III_2	151	155	PF00653	0.650
LIG_BRCT_BRCA1_1	238	242	PF00533	0.568
LIG_Clathr_ClatBox_1	290	294	PF01394	0.610
LIG_Clathr_ClatBox_1	387	391	PF01394	0.576
LIG_FHA_1	163	169	PF00498	0.673
LIG_FHA_1	184	190	PF00498	0.617
LIG_FHA_1	229	235	PF00498	0.626
LIG_FHA_1	38	44	PF00498	0.721
LIG_FHA_1	8	14	PF00498	0.648
LIG_FHA_2	456	462	PF00498	0.653
LIG_FHA_2	52	58	PF00498	0.629
LIG_HCF-1_HBM_1	392	395	PF13415	0.611
LIG_LIR_Apic_2	263	268	PF02991	0.543
LIG_LIR_Apic_2	402	407	PF02991	0.624
LIG_LIR_Gen_1	109	119	PF02991	0.658
LIG_LIR_Gen_1	360	370	PF02991	0.588
LIG_LIR_Gen_1	82	90	PF02991	0.511
LIG_LIR_Nem_3	109	115	PF02991	0.647
LIG_LIR_Nem_3	195	199	PF02991	0.738
LIG_LIR_Nem_3	360	365	PF02991	0.580
LIG_LIR_Nem_3	420	426	PF02991	0.532
LIG_LIR_Nem_3	82	86	PF02991	0.500
LIG_Pex14_1	16	20	PF04695	0.519
LIG_PTAP_UEV_1	229	234	PF05743	0.668
LIG_Rb_pABgroove_1	96	104	PF01858	0.601
LIG_SH2_CRK	112	116	PF00017	0.663
LIG_SH2_CRK	265	269	PF00017	0.603
LIG_SH2_CRK	83	87	PF00017	0.511
LIG_SH2_STAT5	198	201	PF00017	0.577
LIG_SH2_STAT5	20	23	PF00017	0.529
LIG_SH2_STAT5	395	398	PF00017	0.606
LIG_SH3_3	174	180	PF00018	0.594
LIG_SH3_3	22	28	PF00018	0.490
LIG_SH3_3	227	233	PF00018	0.673
LIG_SH3_3	367	373	PF00018	0.615
LIG_SH3_3	9	15	PF00018	0.642
LIG_Sin3_3	22	29	PF02671	0.632
LIG_SUMO_SIM_par_1	140	151	PF11976	0.698
LIG_SUMO_SIM_par_1	362	367	PF11976	0.575
LIG_SUMO_SIM_par_1	374	379	PF11976	0.456
LIG_WRC_WIRS_1	387	392	PF05994	0.585
MOD_CDC14_SPxK_1	118	121	PF00782	0.677
MOD_CDC14_SPxK_1	406	409	PF00782	0.642
MOD_CDK_SPxK_1	115	121	PF00069	0.679
MOD_CDK_SPxK_1	403	409	PF00069	0.634
MOD_CK1_1	130	136	PF00069	0.732
MOD_CK1_1	162	168	PF00069	0.728
MOD_CK1_1	183	189	PF00069	0.619
MOD_CK1_1	224	230	PF00069	0.676
MOD_CK1_1	400	406	PF00069	0.629
MOD_CK1_1	442	448	PF00069	0.649
MOD_CK1_1	82	88	PF00069	0.594
MOD_CK1_1	91	97	PF00069	0.522
MOD_CK2_1	251	257	PF00069	0.518
MOD_CK2_1	278	284	PF00069	0.636
MOD_CK2_1	376	382	PF00069	0.579
MOD_CK2_1	386	392	PF00069	0.468
MOD_CK2_1	455	461	PF00069	0.728
MOD_CK2_1	51	57	PF00069	0.639
MOD_GlcNHglycan	108	111	PF01048	0.413
MOD_GlcNHglycan	141	144	PF01048	0.648
MOD_GlcNHglycan	156	159	PF01048	0.528
MOD_GlcNHglycan	280	283	PF01048	0.576
MOD_GlcNHglycan	30	33	PF01048	0.662
MOD_GlcNHglycan	44	47	PF01048	0.501
MOD_GlcNHglycan	90	93	PF01048	0.634
MOD_GSK3_1	121	128	PF00069	0.700
MOD_GSK3_1	139	146	PF00069	0.487
MOD_GSK3_1	159	166	PF00069	0.455
MOD_GSK3_1	224	231	PF00069	0.683
MOD_GSK3_1	330	337	PF00069	0.547
MOD_GSK3_1	38	45	PF00069	0.685
MOD_GSK3_1	399	406	PF00069	0.641
MOD_N-GLC_1	442	447	PF02516	0.627
MOD_NEK2_1	161	166	PF00069	0.590
MOD_NEK2_1	243	248	PF00069	0.657
MOD_NEK2_1	251	256	PF00069	0.505
MOD_NEK2_1	376	381	PF00069	0.578
MOD_NEK2_1	417	422	PF00069	0.539
MOD_NEK2_1	425	430	PF00069	0.516
MOD_NEK2_1	449	454	PF00069	0.718
MOD_NEK2_2	464	469	PF00069	0.741
MOD_PIKK_1	180	186	PF00454	0.629
MOD_PIKK_1	224	230	PF00454	0.676
MOD_PKA_1	159	165	PF00069	0.690
MOD_PKA_2	1	7	PF00069	0.680
MOD_PKA_2	159	165	PF00069	0.690
MOD_PKA_2	417	423	PF00069	0.622
MOD_PKA_2	449	455	PF00069	0.631
MOD_PKA_2	88	94	PF00069	0.626
MOD_PKB_1	437	445	PF00069	0.630
MOD_Plk_1	294	300	PF00069	0.595
MOD_Plk_2-3	386	392	PF00069	0.585
MOD_Plk_2-3	51	57	PF00069	0.639
MOD_Plk_4	143	149	PF00069	0.700
MOD_Plk_4	260	266	PF00069	0.634
MOD_Plk_4	82	88	PF00069	0.594
MOD_ProDKin_1	115	121	PF00069	0.679
MOD_ProDKin_1	219	225	PF00069	0.753
MOD_ProDKin_1	397	403	PF00069	0.605
MOD_ProDKin_1	8	14	PF00069	0.648
MOD_ProDKin_1	91	97	PF00069	0.627
TRG_DiLeu_BaEn_2	391	397	PF01217	0.613
TRG_DiLeu_BaLyEn_6	286	291	PF01217	0.624
TRG_ENDOCYTIC_2	112	115	PF00928	0.659
TRG_ENDOCYTIC_2	196	199	PF00928	0.738
TRG_ENDOCYTIC_2	83	86	PF00928	0.508
TRG_ER_diArg_1	191	193	PF00400	0.626
TRG_ER_diArg_1	323	326	PF00400	0.487
TRG_Pf-PMV_PEXEL_1	191	195	PF00026	0.702
TRG_Pf-PMV_PEXEL_1	321	325	PF00026	0.599
TRG_Pf-PMV_PEXEL_1	381	385	PF00026	0.565

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IJ59	Leptomonas seymouri	33%	66%