Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HJ72_LEIBR

TriTrypDb:

LbrM.31.1120 , LBRM2903_310019400

Length:

189

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

A4HJ72

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HJ72

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	14	16	PF00675	0.809
CLV_NRD_NRD_1	26	28	PF00675	0.639
CLV_PCSK_KEX2_1	159	161	PF00082	0.779
CLV_PCSK_KEX2_1	26	28	PF00082	0.789
CLV_PCSK_PC1ET2_1	159	161	PF00082	0.779
CLV_PCSK_SKI1_1	58	62	PF00082	0.818
DEG_APCC_DBOX_1	14	22	PF00400	0.592
DEG_APCC_DBOX_1	25	33	PF00400	0.440
DOC_CYCLIN_yClb3_PxF_3	97	105	PF00134	0.608
DOC_CYCLIN_yCln2_LP_2	44	47	PF00134	0.599
DOC_MAPK_gen_1	12	22	PF00069	0.596
DOC_MAPK_gen_1	159	166	PF00069	0.588
DOC_MAPK_gen_1	23	31	PF00069	0.445
DOC_MAPK_JIP1_4	160	166	PF00069	0.591
DOC_MAPK_MEF2A_6	133	141	PF00069	0.650
DOC_MAPK_MEF2A_6	15	22	PF00069	0.590
DOC_MAPK_RevD_3	145	160	PF00069	0.549
DOC_PP2B_LxvP_1	164	167	PF13499	0.596
DOC_PP2B_LxvP_1	44	47	PF13499	0.599
DOC_PP2B_LxvP_1	72	75	PF13499	0.621
DOC_USP7_MATH_1	123	127	PF00917	0.549
DOC_USP7_MATH_1	129	133	PF00917	0.622
DOC_USP7_MATH_1	14	18	PF00917	0.527
DOC_USP7_MATH_1	174	178	PF00917	0.629
DOC_USP7_MATH_1	62	66	PF00917	0.613
DOC_USP7_MATH_1	75	79	PF00917	0.455
DOC_USP7_MATH_1	8	12	PF00917	0.632
DOC_USP7_UBL2_3	12	16	PF12436	0.611
DOC_WW_Pin1_4	10	15	PF00397	0.617
DOC_WW_Pin1_4	45	50	PF00397	0.606
DOC_WW_Pin1_4	67	72	PF00397	0.617
DOC_WW_Pin1_4	79	84	PF00397	0.448
DOC_WW_Pin1_4	93	98	PF00397	0.420
LIG_14-3-3_CanoR_1	105	114	PF00244	0.449
LIG_14-3-3_CanoR_1	15	19	PF00244	0.597
LIG_BRCT_BRCA1_1	56	60	PF00533	0.616
LIG_BRCT_BRCA1_1	77	81	PF00533	0.615
LIG_FHA_2	171	177	PF00498	0.625
LIG_LIR_Gen_1	88	97	PF02991	0.587
LIG_LIR_LC3C_4	17	20	PF02991	0.586
LIG_LIR_Nem_3	134	139	PF02991	0.650
LIG_LIR_Nem_3	57	63	PF02991	0.616
LIG_LIR_Nem_3	78	84	PF02991	0.601
LIG_LIR_Nem_3	88	94	PF02991	0.458
LIG_PDZ_Class_3	184	189	PF00595	0.651
LIG_Pex14_2	136	140	PF04695	0.549
LIG_SH2_STAT5	30	33	PF00017	0.565
LIG_SH3_3	43	49	PF00018	0.600
LIG_SH3_3	65	71	PF00018	0.612
LIG_SH3_3	94	100	PF00018	0.600
LIG_SUMO_SIM_anti_2	17	24	PF11976	0.586
LIG_SUMO_SIM_par_1	17	24	PF11976	0.586
LIG_TRAF2_1	132	135	PF00917	0.782
MOD_CDC14_SPxK_1	13	16	PF00782	0.607
MOD_CDK_SPK_2	10	15	PF00069	0.617
MOD_CDK_SPxK_1	10	16	PF00069	0.616
MOD_CK1_1	109	115	PF00069	0.549
MOD_CK1_1	70	76	PF00069	0.617
MOD_CK2_1	129	135	PF00069	0.730
MOD_CK2_1	170	176	PF00069	0.624
MOD_GlcNHglycan	108	111	PF01048	0.650
MOD_GlcNHglycan	176	179	PF01048	0.836
MOD_GSK3_1	166	173	PF00069	0.611
MOD_GSK3_1	4	11	PF00069	0.640
MOD_GSK3_1	75	82	PF00069	0.612
MOD_NEK2_1	143	148	PF00069	0.549
MOD_NEK2_1	53	58	PF00069	0.611
MOD_NEK2_1	92	97	PF00069	0.591
MOD_PKA_2	14	20	PF00069	0.596
MOD_Plk_4	14	20	PF00069	0.596
MOD_Plk_4	166	172	PF00069	0.608
MOD_Plk_4	40	46	PF00069	0.588
MOD_ProDKin_1	10	16	PF00069	0.616
MOD_ProDKin_1	45	51	PF00069	0.609
MOD_ProDKin_1	67	73	PF00069	0.617
MOD_ProDKin_1	79	85	PF00069	0.446
MOD_ProDKin_1	93	99	PF00069	0.423
TRG_DiLeu_BaEn_1	88	93	PF01217	0.582
TRG_DiLeu_BaLyEn_6	82	87	PF01217	0.582
TRG_ENDOCYTIC_2	33	36	PF00928	0.562