Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

A4HJ55_LEIBR

TriTrypDb:

LbrM.31.0940 , LBRM2903_310016700

Length:

297

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HJ55

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HJ55

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	193	197	PF00656	0.473
CLV_PCSK_SKI1_1	174	178	PF00082	0.593
CLV_PCSK_SKI1_1	190	194	PF00082	0.552
CLV_PCSK_SKI1_1	22	26	PF00082	0.522
DEG_SCF_FBW7_2	138	144	PF00400	0.329
DEG_SPOP_SBC_1	234	238	PF00917	0.499
DOC_CKS1_1	138	143	PF01111	0.325
DOC_CKS1_1	253	258	PF01111	0.554
DOC_CYCLIN_RxL_1	21	32	PF00134	0.322
DOC_MAPK_gen_1	119	127	PF00069	0.334
DOC_MAPK_MEF2A_6	92	99	PF00069	0.335
DOC_PP4_FxxP_1	257	260	PF00568	0.504
DOC_PP4_MxPP_1	232	235	PF00568	0.555
DOC_USP7_MATH_1	228	232	PF00917	0.657
DOC_USP7_MATH_1	235	239	PF00917	0.632
DOC_USP7_MATH_1	271	275	PF00917	0.570
DOC_USP7_UBL2_3	133	137	PF12436	0.611
DOC_USP7_UBL2_3	153	157	PF12436	0.419
DOC_WW_Pin1_4	137	142	PF00397	0.476
DOC_WW_Pin1_4	252	257	PF00397	0.701
DOC_WW_Pin1_4	91	96	PF00397	0.364
LIG_Actin_WH2_2	93	110	PF00022	0.480
LIG_FHA_1	187	193	PF00498	0.543
LIG_FHA_1	253	259	PF00498	0.551
LIG_FHA_1	278	284	PF00498	0.505
LIG_FHA_1	79	85	PF00498	0.395
LIG_FHA_2	100	106	PF00498	0.510
LIG_FHA_2	191	197	PF00498	0.571
LIG_LIR_Apic_2	251	256	PF02991	0.538
LIG_LIR_Gen_1	196	205	PF02991	0.508
LIG_LIR_Gen_1	264	275	PF02991	0.492
LIG_LIR_Nem_3	196	202	PF02991	0.446
LIG_LIR_Nem_3	264	270	PF02991	0.489
LIG_SH2_CRK	253	257	PF00017	0.610
LIG_SH2_CRK	267	271	PF00017	0.493
LIG_SH2_GRB2like	88	91	PF00017	0.483
LIG_SH2_NCK_1	267	271	PF00017	0.493
LIG_SH2_STAP1	199	203	PF00017	0.348
LIG_SH2_STAT3	5	8	PF00017	0.453
LIG_SH2_STAT5	199	202	PF00017	0.518
LIG_SH2_STAT5	41	44	PF00017	0.434
LIG_SH2_STAT5	5	8	PF00017	0.643
LIG_SH3_2	218	223	PF14604	0.467
LIG_SH3_3	135	141	PF00018	0.495
LIG_SH3_3	215	221	PF00018	0.611
LIG_SH3_3	222	228	PF00018	0.693
LIG_SH3_3	73	79	PF00018	0.641
LIG_SUMO_SIM_par_1	179	186	PF11976	0.376
MOD_CDK_SPxxK_3	91	98	PF00069	0.333
MOD_CK1_1	182	188	PF00069	0.473
MOD_CK1_1	238	244	PF00069	0.666
MOD_CK1_1	248	254	PF00069	0.565
MOD_CK1_1	261	267	PF00069	0.557
MOD_CK1_1	4	10	PF00069	0.470
MOD_CK1_1	61	67	PF00069	0.414
MOD_CK2_1	271	277	PF00069	0.607
MOD_CK2_1	99	105	PF00069	0.472
MOD_GlcNHglycan	109	113	PF01048	0.464
MOD_GlcNHglycan	237	240	PF01048	0.796
MOD_GlcNHglycan	247	250	PF01048	0.525
MOD_GlcNHglycan	260	263	PF01048	0.499
MOD_GlcNHglycan	273	276	PF01048	0.560
MOD_GSK3_1	133	140	PF00069	0.576
MOD_GSK3_1	179	186	PF00069	0.405
MOD_GSK3_1	234	241	PF00069	0.614
MOD_GSK3_1	245	252	PF00069	0.515
MOD_GSK3_1	277	284	PF00069	0.506
MOD_GSK3_1	74	81	PF00069	0.480
MOD_N-GLC_1	53	58	PF02516	0.527
MOD_NEK2_1	1	6	PF00069	0.676
MOD_NEK2_1	183	188	PF00069	0.505
MOD_NEK2_1	213	218	PF00069	0.623
MOD_PIKK_1	4	10	PF00454	0.436
MOD_PIKK_1	71	77	PF00454	0.616
MOD_PKA_1	133	139	PF00069	0.424
MOD_PKA_2	245	251	PF00069	0.500
MOD_Plk_4	1	7	PF00069	0.560
MOD_Plk_4	238	244	PF00069	0.599
MOD_ProDKin_1	137	143	PF00069	0.472
MOD_ProDKin_1	252	258	PF00069	0.699
MOD_ProDKin_1	91	97	PF00069	0.357
MOD_SUMO_for_1	170	173	PF00179	0.315
MOD_SUMO_rev_2	142	147	PF00179	0.475
MOD_SUMO_rev_2	94	100	PF00179	0.348
TRG_ENDOCYTIC_2	199	202	PF00928	0.506
TRG_ENDOCYTIC_2	267	270	PF00928	0.492
TRG_Pf-PMV_PEXEL_1	157	161	PF00026	0.565
TRG_Pf-PMV_PEXEL_1	22	26	PF00026	0.466

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PAJ7	Leptomonas seymouri	41%	100%
A0A0N1PCN3	Leptomonas seymouri	32%	82%
A0A3Q8IJW3	Leishmania donovani	65%	100%
A4I6G9	Leishmania infantum	65%	100%
E9B1M6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	65%	100%
Q9BHD3	Leishmania major	63%	100%