Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

A4HJ49_LEIBR

TriTrypDb:

LbrM.31.0880 , LBRM2903_310016100

Length:

158

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HJ49

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HJ49

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	65	69	PF00656	0.611
CLV_NRD_NRD_1	82	84	PF00675	0.654
CLV_PCSK_KEX2_1	82	84	PF00082	0.500
CLV_PCSK_SKI1_1	89	93	PF00082	0.504
DEG_APCC_DBOX_1	111	119	PF00400	0.497
DEG_Nend_UBRbox_2	1	3	PF02207	0.527
DOC_CKS1_1	118	123	PF01111	0.601
DOC_CKS1_1	129	134	PF01111	0.646
DOC_CKS1_1	90	95	PF01111	0.511
DOC_CYCLIN_yCln2_LP_2	73	79	PF00134	0.537
DOC_MAPK_MEF2A_6	46	53	PF00069	0.555
DOC_PP2B_LxvP_1	119	122	PF13499	0.603
DOC_PP2B_LxvP_1	73	76	PF13499	0.549
DOC_USP7_MATH_1	114	118	PF00917	0.589
DOC_USP7_MATH_1	122	126	PF00917	0.657
DOC_USP7_MATH_1	136	140	PF00917	0.645
DOC_WW_Pin1_4	117	122	PF00397	0.659
DOC_WW_Pin1_4	128	133	PF00397	0.641
DOC_WW_Pin1_4	63	68	PF00397	0.779
DOC_WW_Pin1_4	89	94	PF00397	0.516
LIG_14-3-3_CanoR_1	29	33	PF00244	0.496
LIG_14-3-3_CanoR_1	83	89	PF00244	0.511
LIG_FHA_1	13	19	PF00498	0.556
LIG_FHA_2	143	149	PF00498	0.560
LIG_FHA_2	15	21	PF00498	0.482
LIG_FHA_2	63	69	PF00498	0.665
LIG_FHA_2	98	104	PF00498	0.665
LIG_LIR_Apic_2	107	113	PF02991	0.504
LIG_LIR_Nem_3	32	38	PF02991	0.553
LIG_LIR_Nem_3	43	48	PF02991	0.644
LIG_LIR_Nem_3	87	91	PF02991	0.518
LIG_Pex14_2	38	42	PF04695	0.483
LIG_SH2_CRK	88	92	PF00017	0.506
LIG_SH3_1	126	132	PF00018	0.525
LIG_SH3_3	115	121	PF00018	0.596
LIG_SH3_3	126	132	PF00018	0.598
LIG_SH3_3	30	36	PF00018	0.509
LIG_SH3_3	73	79	PF00018	0.557
LIG_SH3_3	88	94	PF00018	0.504
LIG_SUMO_SIM_par_1	14	20	PF11976	0.585
LIG_WRC_WIRS_1	35	40	PF05994	0.489
MOD_CDK_SPK_2	128	133	PF00069	0.528
MOD_CDK_SPxxK_3	128	135	PF00069	0.533
MOD_CK1_1	117	123	PF00069	0.500
MOD_CK1_1	12	18	PF00069	0.489
MOD_CK1_1	28	34	PF00069	0.667
MOD_CK1_1	3	9	PF00069	0.514
MOD_CK1_1	60	66	PF00069	0.702
MOD_CK2_1	101	107	PF00069	0.497
MOD_CK2_1	122	128	PF00069	0.515
MOD_CK2_1	14	20	PF00069	0.520
MOD_CK2_1	142	148	PF00069	0.561
MOD_CK2_1	92	98	PF00069	0.517
MOD_GlcNHglycan	11	14	PF01048	0.563
MOD_GlcNHglycan	2	5	PF01048	0.580
MOD_GlcNHglycan	62	65	PF01048	0.639
MOD_GSK3_1	127	134	PF00069	0.630
MOD_GSK3_1	137	144	PF00069	0.606
MOD_GSK3_1	27	34	PF00069	0.507
MOD_GSK3_1	3	10	PF00069	0.498
MOD_GSK3_1	59	66	PF00069	0.761
MOD_GSK3_1	97	104	PF00069	0.700
MOD_N-GLC_1	38	43	PF02516	0.590
MOD_NEK2_1	14	19	PF00069	0.515
MOD_NEK2_1	57	62	PF00069	0.733
MOD_PKA_2	28	34	PF00069	0.529
MOD_Plk_1	57	63	PF00069	0.671
MOD_Plk_1	97	103	PF00069	0.593
MOD_Plk_2-3	99	105	PF00069	0.519
MOD_Plk_4	114	120	PF00069	0.500
MOD_Plk_4	69	75	PF00069	0.543
MOD_ProDKin_1	117	123	PF00069	0.659
MOD_ProDKin_1	128	134	PF00069	0.643
MOD_ProDKin_1	63	69	PF00069	0.781
MOD_ProDKin_1	89	95	PF00069	0.515
TRG_ENDOCYTIC_2	35	38	PF00928	0.534
TRG_ENDOCYTIC_2	54	57	PF00928	0.496
TRG_ENDOCYTIC_2	88	91	PF00928	0.540

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IG87	Leishmania donovani	50%	100%
A4I6G5	Leishmania infantum	50%	100%
E9B1M2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	52%	100%
Q9BHG5	Leishmania major	46%	100%