Putative ATP-dependent zinc metallopeptidase

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

metallo-peptidase, Clan MA(E), Family M41

Species:

Leishmania braziliensis

UniProt:

A4HJ48_LEIBR

TriTrypDb:

LbrM.31.0870 , LBRM2903_310016000

Length:

1030

Annotations

LeishMANIAdb annotations

Homologous to bacterial FtsH and Eukaryotic AFG3 proteins. Probably involved in mitochondrial protein processing.. Localization: Mitochondrial (by homology)

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 13
NetGPI	no	yes: 0, no: 13

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	10
GO:0110165	cellular anatomical entity	1	11
GO:0005739	mitochondrion	5	1
GO:0005745	m-AAA complex	4	2
GO:0032991	protein-containing complex	1	2
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0098796	membrane protein complex	2	2
GO:0098798	mitochondrial protein-containing complex	2	2
GO:0098800	inner mitochondrial membrane protein complex	3	2
GO:1902494	catalytic complex	2	2
GO:1905368	peptidase complex	3	2

Expansion

Sequence features

A4HJ48

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HJ48

Function

Biological processes
Term	Name	Level	Count
GO:0006508	proteolysis	4	14
GO:0006807	nitrogen compound metabolic process	2	14
GO:0008152	metabolic process	1	14
GO:0019538	protein metabolic process	3	14
GO:0043170	macromolecule metabolic process	3	14
GO:0044238	primary metabolic process	2	14
GO:0071704	organic substance metabolic process	2	14
GO:1901564	organonitrogen compound metabolic process	3	14
GO:0009987	cellular process	1	2
GO:0016043	cellular component organization	3	2
GO:0016485	protein processing	5	2
GO:0022607	cellular component assembly	4	2
GO:0034982	mitochondrial protein processing	6	2
GO:0043933	protein-containing complex organization	4	2
GO:0051604	protein maturation	4	2
GO:0065003	protein-containing complex assembly	5	2
GO:0071840	cellular component organization or biogenesis	2	2

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	14
GO:0003824	catalytic activity	1	14
GO:0004175	endopeptidase activity	4	14
GO:0004176	ATP-dependent peptidase activity	2	14
GO:0004222	metalloendopeptidase activity	5	14
GO:0005488	binding	1	14
GO:0005524	ATP binding	5	14
GO:0008233	peptidase activity	3	14
GO:0008237	metallopeptidase activity	4	14
GO:0016462	pyrophosphatase activity	5	14
GO:0016787	hydrolase activity	2	14
GO:0016817	hydrolase activity, acting on acid anhydrides	3	14
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	14
GO:0016887	ATP hydrolysis activity	7	14
GO:0017076	purine nucleotide binding	4	14
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	14
GO:0030554	adenyl nucleotide binding	5	14
GO:0032553	ribonucleotide binding	3	14
GO:0032555	purine ribonucleotide binding	4	14
GO:0032559	adenyl ribonucleotide binding	5	14
GO:0035639	purine ribonucleoside triphosphate binding	4	14
GO:0036094	small molecule binding	2	14
GO:0043167	ion binding	2	14
GO:0043168	anion binding	3	14
GO:0097159	organic cyclic compound binding	2	14
GO:0097367	carbohydrate derivative binding	2	14
GO:0140096	catalytic activity, acting on a protein	2	14
GO:0140657	ATP-dependent activity	1	14
GO:1901265	nucleoside phosphate binding	3	14
GO:1901363	heterocyclic compound binding	2	14

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	260	264	PF00656	0.641
CLV_C14_Caspase3-7	360	364	PF00656	0.458
CLV_C14_Caspase3-7	577	581	PF00656	0.460
CLV_C14_Caspase3-7	606	610	PF00656	0.437
CLV_C14_Caspase3-7	896	900	PF00656	0.437
CLV_NRD_NRD_1	230	232	PF00675	0.454
CLV_NRD_NRD_1	409	411	PF00675	0.709
CLV_NRD_NRD_1	567	569	PF00675	0.328
CLV_NRD_NRD_1	615	617	PF00675	0.320
CLV_NRD_NRD_1	84	86	PF00675	0.372
CLV_NRD_NRD_1	926	928	PF00675	0.253
CLV_NRD_NRD_1	970	972	PF00675	0.320
CLV_PCSK_KEX2_1	230	232	PF00082	0.468
CLV_PCSK_KEX2_1	585	587	PF00082	0.226
CLV_PCSK_KEX2_1	615	617	PF00082	0.253
CLV_PCSK_KEX2_1	746	748	PF00082	0.502
CLV_PCSK_KEX2_1	84	86	PF00082	0.373
CLV_PCSK_KEX2_1	970	972	PF00082	0.320
CLV_PCSK_PC1ET2_1	585	587	PF00082	0.226
CLV_PCSK_PC1ET2_1	746	748	PF00082	0.444
CLV_PCSK_SKI1_1	489	493	PF00082	0.312
CLV_PCSK_SKI1_1	525	529	PF00082	0.260
CLV_PCSK_SKI1_1	561	565	PF00082	0.269
CLV_PCSK_SKI1_1	743	747	PF00082	0.411
CLV_PCSK_SKI1_1	763	767	PF00082	0.393
CLV_PCSK_SKI1_1	892	896	PF00082	0.277
CLV_PCSK_SKI1_1	955	959	PF00082	0.232
CLV_PCSK_SKI1_1	970	974	PF00082	0.260
DEG_APCC_DBOX_1	13	21	PF00400	0.562
DEG_APCC_DBOX_1	286	294	PF00400	0.437
DEG_APCC_DBOX_1	86	94	PF00400	0.561
DEG_Nend_UBRbox_2	1	3	PF02207	0.573
DEG_SCF_FBW7_1	648	654	PF00400	0.587
DEG_SPOP_SBC_1	182	186	PF00917	0.660
DEG_SPOP_SBC_1	949	953	PF00917	0.422
DOC_CDC14_PxL_1	63	71	PF14671	0.540
DOC_CKS1_1	124	129	PF01111	0.565
DOC_CKS1_1	648	653	PF01111	0.586
DOC_CKS1_1	70	75	PF01111	0.534
DOC_CYCLIN_RxL_1	558	566	PF00134	0.460
DOC_CYCLIN_yCln2_LP_2	35	41	PF00134	0.552
DOC_CYCLIN_yCln2_LP_2	956	962	PF00134	0.520
DOC_MAPK_gen_1	460	468	PF00069	0.597
DOC_MAPK_gen_1	568	576	PF00069	0.460
DOC_MAPK_gen_1	615	622	PF00069	0.453
DOC_MAPK_gen_1	638	648	PF00069	0.460
DOC_MAPK_gen_1	809	817	PF00069	0.377
DOC_MAPK_gen_1	84	92	PF00069	0.563
DOC_MAPK_gen_1	895	905	PF00069	0.497
DOC_MAPK_JIP1_4	402	408	PF00069	0.381
DOC_MAPK_MEF2A_6	809	817	PF00069	0.442
DOC_MAPK_MEF2A_6	862	871	PF00069	0.457
DOC_MAPK_MEF2A_6	898	905	PF00069	0.437
DOC_PP2B_LxvP_1	136	139	PF13499	0.579
DOC_PP2B_LxvP_1	209	212	PF13499	0.673
DOC_PP2B_LxvP_1	35	38	PF13499	0.548
DOC_PP2B_LxvP_1	518	521	PF13499	0.426
DOC_PP2B_LxvP_1	704	707	PF13499	0.656
DOC_PP4_FxxP_1	124	127	PF00568	0.574
DOC_PP4_FxxP_1	29	32	PF00568	0.543
DOC_USP7_MATH_1	105	109	PF00917	0.559
DOC_USP7_MATH_1	127	131	PF00917	0.570
DOC_USP7_MATH_1	149	153	PF00917	0.580
DOC_USP7_MATH_1	164	168	PF00917	0.638
DOC_USP7_MATH_1	232	236	PF00917	0.788
DOC_USP7_MATH_1	306	310	PF00917	0.449
DOC_USP7_MATH_1	533	537	PF00917	0.437
DOC_USP7_MATH_1	543	547	PF00917	0.437
DOC_USP7_MATH_1	732	736	PF00917	0.809
DOC_USP7_MATH_1	949	953	PF00917	0.386
DOC_USP7_UBL2_3	458	462	PF12436	0.617
DOC_USP7_UBL2_3	506	510	PF12436	0.621
DOC_USP7_UBL2_3	565	569	PF12436	0.497
DOC_USP7_UBL2_3	991	995	PF12436	0.533
DOC_WW_Pin1_4	123	128	PF00397	0.578
DOC_WW_Pin1_4	129	134	PF00397	0.580
DOC_WW_Pin1_4	647	652	PF00397	0.546
DOC_WW_Pin1_4	69	74	PF00397	0.533
LIG_14-3-3_CanoR_1	1022	1030	PF00244	0.714
LIG_14-3-3_CanoR_1	115	121	PF00244	0.758
LIG_14-3-3_CanoR_1	16	21	PF00244	0.550
LIG_14-3-3_CanoR_1	171	179	PF00244	0.621
LIG_14-3-3_CanoR_1	198	202	PF00244	0.599
LIG_14-3-3_CanoR_1	231	237	PF00244	0.595
LIG_14-3-3_CanoR_1	42	48	PF00244	0.554
LIG_14-3-3_CanoR_1	6	12	PF00244	0.570
LIG_14-3-3_CanoR_1	74	80	PF00244	0.585
LIG_14-3-3_CanoR_1	834	839	PF00244	0.593
LIG_Actin_WH2_2	655	670	PF00022	0.507
LIG_Actin_WH2_2	911	929	PF00022	0.437
LIG_APCC_ABBA_1	211	216	PF00400	0.578
LIG_APCC_ABBA_1	335	340	PF00400	0.373
LIG_APCC_ABBAyCdc20_2	571	577	PF00400	0.426
LIG_BIR_III_4	580	584	PF00653	0.460
LIG_BIR_III_4	673	677	PF00653	0.573
LIG_BIR_III_4	692	696	PF00653	0.604
LIG_BRCT_BRCA1_1	61	65	PF00533	0.548
LIG_eIF4E_1	415	421	PF01652	0.278
LIG_EVH1_1	69	73	PF00568	0.528
LIG_FAT_LD_1	221	229	PF03623	0.564
LIG_FHA_1	231	237	PF00498	0.714
LIG_FHA_1	297	303	PF00498	0.358
LIG_FHA_1	416	422	PF00498	0.277
LIG_FHA_1	490	496	PF00498	0.491
LIG_FHA_1	511	517	PF00498	0.495
LIG_FHA_1	648	654	PF00498	0.587
LIG_FHA_1	70	76	PF00498	0.537
LIG_FHA_1	710	716	PF00498	0.686
LIG_FHA_1	952	958	PF00498	0.426
LIG_FHA_1	981	987	PF00498	0.426
LIG_FHA_2	1006	1012	PF00498	0.426
LIG_FHA_2	381	387	PF00498	0.541
LIG_FHA_2	396	402	PF00498	0.442
LIG_FHA_2	598	604	PF00498	0.441
LIG_FHA_2	668	674	PF00498	0.645
LIG_FHA_2	719	725	PF00498	0.744
LIG_FHA_2	835	841	PF00498	0.422
LIG_FHA_2	891	897	PF00498	0.426
LIG_Integrin_RGD_1	616	618	PF01839	0.237
LIG_LIR_Apic_2	122	127	PF02991	0.575
LIG_LIR_Apic_2	281	286	PF02991	0.663
LIG_LIR_Apic_2	83	89	PF02991	0.552
LIG_LIR_Apic_2	944	949	PF02991	0.477
LIG_LIR_Gen_1	1008	1016	PF02991	0.426
LIG_LIR_Gen_1	120	129	PF02991	0.569
LIG_LIR_Gen_1	167	177	PF02991	0.719
LIG_LIR_Gen_1	313	322	PF02991	0.326
LIG_LIR_Gen_1	332	342	PF02991	0.415
LIG_LIR_Gen_1	502	512	PF02991	0.563
LIG_LIR_Gen_1	546	555	PF02991	0.458
LIG_LIR_Gen_1	77	86	PF02991	0.557
LIG_LIR_Gen_1	912	922	PF02991	0.533
LIG_LIR_Nem_3	1008	1012	PF02991	0.426
LIG_LIR_Nem_3	120	124	PF02991	0.576
LIG_LIR_Nem_3	167	172	PF02991	0.729
LIG_LIR_Nem_3	313	318	PF02991	0.417
LIG_LIR_Nem_3	332	337	PF02991	0.370
LIG_LIR_Nem_3	476	481	PF02991	0.546
LIG_LIR_Nem_3	502	507	PF02991	0.563
LIG_LIR_Nem_3	546	551	PF02991	0.458
LIG_LIR_Nem_3	62	68	PF02991	0.546
LIG_LIR_Nem_3	759	765	PF02991	0.535
LIG_LIR_Nem_3	77	82	PF02991	0.578
LIG_LIR_Nem_3	912	918	PF02991	0.590
LIG_MYND_1	67	71	PF01753	0.532
LIG_NRBOX	220	226	PF00104	0.616
LIG_NRBOX	600	606	PF00104	0.426
LIG_PCNA_PIPBox_1	994	1003	PF02747	0.426
LIG_Pex14_1	197	201	PF04695	0.540
LIG_Pex14_1	428	432	PF04695	0.251
LIG_Pex14_2	434	438	PF04695	0.251
LIG_PTB_Apo_2	884	891	PF02174	0.448
LIG_SH2_CRK	169	173	PF00017	0.710
LIG_SH2_CRK	504	508	PF00017	0.515
LIG_SH2_CRK	934	938	PF00017	0.437
LIG_SH2_GRB2like	331	334	PF00017	0.301
LIG_SH2_NCK_1	169	173	PF00017	0.688
LIG_SH2_SRC	1009	1012	PF00017	0.477
LIG_SH2_SRC	68	71	PF00017	0.534
LIG_SH2_SRC	934	937	PF00017	0.477
LIG_SH2_STAP1	1009	1013	PF00017	0.453
LIG_SH2_STAP1	201	205	PF00017	0.581
LIG_SH2_STAP1	331	335	PF00017	0.312
LIG_SH2_STAP1	415	419	PF00017	0.282
LIG_SH2_STAP1	452	456	PF00017	0.679
LIG_SH2_STAP1	780	784	PF00017	0.518
LIG_SH2_STAP1	881	885	PF00017	0.460
LIG_SH2_STAP1	980	984	PF00017	0.437
LIG_SH2_STAT5	1015	1018	PF00017	0.512
LIG_SH2_STAT5	160	163	PF00017	0.648
LIG_SH2_STAT5	169	172	PF00017	0.656
LIG_SH2_STAT5	334	337	PF00017	0.282
LIG_SH2_STAT5	345	348	PF00017	0.310
LIG_SH2_STAT5	445	448	PF00017	0.667
LIG_SH2_STAT5	504	507	PF00017	0.549
LIG_SH2_STAT5	552	555	PF00017	0.426
LIG_SH2_STAT5	575	578	PF00017	0.426
LIG_SH2_STAT5	63	66	PF00017	0.550
LIG_SH2_STAT5	68	71	PF00017	0.673
LIG_SH2_STAT5	884	887	PF00017	0.455
LIG_SH2_STAT5	936	939	PF00017	0.453
LIG_SH3_3	397	403	PF00018	0.369
LIG_SH3_3	64	70	PF00018	0.542
LIG_SH3_3	645	651	PF00018	0.476
LIG_SH3_3	942	948	PF00018	0.454
LIG_SUMO_SIM_anti_2	618	625	PF11976	0.469
LIG_SUMO_SIM_anti_2	88	94	PF11976	0.561
LIG_SUMO_SIM_anti_2	982	988	PF11976	0.520
LIG_SUMO_SIM_par_1	294	299	PF11976	0.296
LIG_SUMO_SIM_par_1	401	407	PF11976	0.316
LIG_SUMO_SIM_par_1	982	988	PF11976	0.520
LIG_TRAF2_1	272	275	PF00917	0.706
LIG_TRAF2_1	727	730	PF00917	0.778
LIG_TRAF2_1	909	912	PF00917	0.377
LIG_TYR_ITIM	1007	1012	PF00017	0.453
LIG_TYR_ITIM	932	937	PF00017	0.377
LIG_WRC_WIRS_1	121	126	PF05994	0.576
LIG_WRC_WIRS_1	76	81	PF05994	0.558
LIG_WRC_WIRS_1	937	942	PF05994	0.437
MOD_CDK_SPK_2	69	74	PF00069	0.533
MOD_CK1_1	109	115	PF00069	0.655
MOD_CK1_1	117	123	PF00069	0.732
MOD_CK1_1	15	21	PF00069	0.558
MOD_CK1_1	159	165	PF00069	0.627
MOD_CK1_1	167	173	PF00069	0.631
MOD_CK1_1	183	189	PF00069	0.631
MOD_CK1_1	235	241	PF00069	0.766
MOD_CK1_1	251	257	PF00069	0.668
MOD_CK1_1	380	386	PF00069	0.466
MOD_CK1_1	709	715	PF00069	0.735
MOD_CK1_1	735	741	PF00069	0.686
MOD_CK1_1	951	957	PF00069	0.474
MOD_CK2_1	16	22	PF00069	0.556
MOD_CK2_1	262	268	PF00069	0.629
MOD_CK2_1	382	388	PF00069	0.486
MOD_CK2_1	597	603	PF00069	0.451
MOD_CK2_1	718	724	PF00069	0.708
MOD_CK2_1	753	759	PF00069	0.720
MOD_CK2_1	767	773	PF00069	0.547
MOD_CK2_1	815	821	PF00069	0.453
MOD_CK2_1	836	842	PF00069	0.426
MOD_CK2_1	890	896	PF00069	0.426
MOD_Cter_Amidation	613	616	PF01082	0.277
MOD_GlcNHglycan	116	119	PF01048	0.416
MOD_GlcNHglycan	129	132	PF01048	0.375
MOD_GlcNHglycan	140	143	PF01048	0.405
MOD_GlcNHglycan	162	165	PF01048	0.397
MOD_GlcNHglycan	24	27	PF01048	0.350
MOD_GlcNHglycan	256	259	PF01048	0.425
MOD_GlcNHglycan	308	311	PF01048	0.590
MOD_GlcNHglycan	535	538	PF01048	0.261
MOD_GlcNHglycan	677	680	PF01048	0.538
MOD_GlcNHglycan	698	701	PF01048	0.530
MOD_GlcNHglycan	733	737	PF01048	0.595
MOD_GlcNHglycan	749	752	PF01048	0.443
MOD_GlcNHglycan	755	758	PF01048	0.460
MOD_GlcNHglycan	876	879	PF01048	0.226
MOD_GSK3_1	1017	1024	PF00069	0.604
MOD_GSK3_1	105	112	PF00069	0.675
MOD_GSK3_1	119	126	PF00069	0.610
MOD_GSK3_1	156	163	PF00069	0.613
MOD_GSK3_1	181	188	PF00069	0.736
MOD_GSK3_1	230	237	PF00069	0.592
MOD_GSK3_1	257	264	PF00069	0.656
MOD_GSK3_1	306	313	PF00069	0.349
MOD_GSK3_1	454	461	PF00069	0.705
MOD_GSK3_1	469	476	PF00069	0.641
MOD_GSK3_1	55	62	PF00069	0.548
MOD_GSK3_1	6	13	PF00069	0.571
MOD_GSK3_1	647	654	PF00069	0.615
MOD_GSK3_1	675	682	PF00069	0.647
MOD_GSK3_1	706	713	PF00069	0.672
MOD_GSK3_1	714	721	PF00069	0.712
MOD_GSK3_1	747	754	PF00069	0.696
MOD_GSK3_1	832	839	PF00069	0.548
MOD_GSK3_1	897	904	PF00069	0.432
MOD_GSK3_1	916	923	PF00069	0.378
MOD_N-GLC_1	251	256	PF02516	0.427
MOD_N-GLC_1	888	893	PF02516	0.326
MOD_N-GLC_2	786	788	PF02516	0.271
MOD_N-GLC_2	798	800	PF02516	0.203
MOD_NEK2_1	106	111	PF00069	0.605
MOD_NEK2_1	215	220	PF00069	0.602
MOD_NEK2_1	224	229	PF00069	0.644
MOD_NEK2_1	291	296	PF00069	0.204
MOD_NEK2_1	406	411	PF00069	0.444
MOD_NEK2_1	440	445	PF00069	0.383
MOD_NEK2_1	622	627	PF00069	0.431
MOD_NEK2_1	714	719	PF00069	0.680
MOD_NEK2_1	75	80	PF00069	0.647
MOD_NEK2_1	867	872	PF00069	0.443
MOD_NEK2_1	890	895	PF00069	0.497
MOD_PIKK_1	215	221	PF00454	0.618
MOD_PIKK_1	351	357	PF00454	0.355
MOD_PIKK_1	372	378	PF00454	0.432
MOD_PIKK_1	440	446	PF00454	0.517
MOD_PIKK_1	603	609	PF00454	0.437
MOD_PIKK_1	714	720	PF00454	0.749
MOD_PK_1	16	22	PF00069	0.556
MOD_PKA_1	230	236	PF00069	0.572
MOD_PKA_2	1018	1024	PF00069	0.561
MOD_PKA_2	114	120	PF00069	0.628
MOD_PKA_2	15	21	PF00069	0.550
MOD_PKA_2	167	173	PF00069	0.706
MOD_PKA_2	197	203	PF00069	0.624
MOD_PKA_2	230	236	PF00069	0.610
MOD_PKA_2	261	267	PF00069	0.717
MOD_PKA_2	377	383	PF00069	0.363
MOD_PKA_2	5	11	PF00069	0.572
MOD_PKA_2	502	508	PF00069	0.515
MOD_PKA_2	782	788	PF00069	0.511
MOD_PKA_2	897	903	PF00069	0.437
MOD_PKB_1	14	22	PF00069	0.559
MOD_PKB_1	834	842	PF00069	0.477
MOD_Plk_1	597	603	PF00069	0.460
MOD_Plk_1	710	716	PF00069	0.664
MOD_Plk_1	815	821	PF00069	0.422
MOD_Plk_2-3	1005	1011	PF00069	0.426
MOD_Plk_2-3	724	730	PF00069	0.638
MOD_Plk_4	149	155	PF00069	0.669
MOD_Plk_4	156	162	PF00069	0.719
MOD_Plk_4	16	22	PF00069	0.556
MOD_Plk_4	192	198	PF00069	0.672
MOD_Plk_4	523	529	PF00069	0.460
MOD_Plk_4	710	716	PF00069	0.697
MOD_Plk_4	867	873	PF00069	0.460
MOD_Plk_4	88	94	PF00069	0.623
MOD_Plk_4	941	947	PF00069	0.477
MOD_ProDKin_1	123	129	PF00069	0.574
MOD_ProDKin_1	647	653	PF00069	0.546
MOD_ProDKin_1	69	75	PF00069	0.536
MOD_SUMO_for_1	1002	1005	PF00179	0.477
MOD_SUMO_for_1	487	490	PF00179	0.519
MOD_SUMO_for_1	719	722	PF00179	0.688
MOD_SUMO_rev_2	249	257	PF00179	0.589
MOD_SUMO_rev_2	274	280	PF00179	0.716
MOD_SUMO_rev_2	340	344	PF00179	0.334
MOD_SUMO_rev_2	738	748	PF00179	0.719
MOD_SUMO_rev_2	992	997	PF00179	0.520
TRG_DiLeu_BaEn_2	492	498	PF01217	0.484
TRG_DiLeu_BaLyEn_6	71	76	PF01217	0.541
TRG_ENDOCYTIC_2	1009	1012	PF00928	0.453
TRG_ENDOCYTIC_2	169	172	PF00928	0.706
TRG_ENDOCYTIC_2	334	337	PF00928	0.267
TRG_ENDOCYTIC_2	345	348	PF00928	0.309
TRG_ENDOCYTIC_2	504	507	PF00928	0.549
TRG_ENDOCYTIC_2	552	555	PF00928	0.426
TRG_ENDOCYTIC_2	934	937	PF00928	0.426
TRG_ER_diArg_1	14	17	PF00400	0.566
TRG_ER_diArg_1	230	232	PF00400	0.712
TRG_ER_diArg_1	39	42	PF00400	0.556
TRG_ER_diArg_1	558	561	PF00400	0.426
TRG_ER_diArg_1	84	86	PF00400	0.574
TRG_ER_diLys_1	1026	1030	PF00400	0.676
TRG_NES_CRM1_1	550	562	PF08389	0.426
TRG_NLS_MonoExtC_3	409	414	PF00514	0.301
TRG_NLS_MonoExtN_4	565	572	PF00514	0.497
TRG_Pf-PMV_PEXEL_1	146	151	PF00026	0.318
TRG_Pf-PMV_PEXEL_1	561	566	PF00026	0.260
TRG_Pf-PMV_PEXEL_1	763	768	PF00026	0.403
TRG_Pf-PMV_PEXEL_1	774	778	PF00026	0.310
TRG_Pf-PMV_PEXEL_1	836	840	PF00026	0.320

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PGD9	Leptomonas seymouri	67%	100%
A0A0S4JTL4	Bodo saltans	57%	100%
A0A1X0NJP5	Trypanosomatidae	59%	100%
A0A3Q8ICE7	Leishmania donovani	83%	100%
A0A3Q8IFG3	Leishmania donovani	31%	100%
A0A422NQX8	Trypanosoma rangeli	62%	100%
A4I6G4	Leishmania infantum	84%	100%
A4I809	Leishmania infantum	31%	100%
C9ZN81	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	59%	100%
E9B1M1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%
Q4Q5D1	Leishmania major	31%	100%
Q4Q6J3	Leishmania major	82%	99%