J domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DnaJ domain containing protein, putative

Species:

Leishmania braziliensis

UniProt:

A4HJ29_LEIBR

TriTrypDb:

LbrM.31.0670 , LBRM2903_310013600

Length:

595

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 13
NetGPI	no	yes: 0, no: 13

Show entries

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	3
GO:0110165	cellular anatomical entity	1	3

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Expansion

Sequence features

A4HJ29

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HJ29

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	407	411	PF00656	0.614
CLV_NRD_NRD_1	225	227	PF00675	0.431
CLV_NRD_NRD_1	293	295	PF00675	0.285
CLV_NRD_NRD_1	298	300	PF00675	0.263
CLV_NRD_NRD_1	397	399	PF00675	0.313
CLV_NRD_NRD_1	486	488	PF00675	0.418
CLV_PCSK_KEX2_1	396	398	PF00082	0.298
CLV_PCSK_KEX2_1	457	459	PF00082	0.417
CLV_PCSK_KEX2_1	486	488	PF00082	0.450
CLV_PCSK_PC1ET2_1	457	459	PF00082	0.430

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IBU7	Leptomonas seymouri	60%	98%
A0A0S4JJ62	Bodo saltans	30%	100%
A0A1X0NJF9	Trypanosomatidae	43%	100%
A0A1X0NZV2	Trypanosomatidae	42%	100%
A0A3S7X455	Leishmania donovani	79%	99%
A0A422NZZ9	Trypanosoma rangeli	40%	100%
A4I6K8	Leishmania infantum	80%	99%
C9ZN58	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	100%
C9ZWY2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	100%
E9B1K1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	80%	99%

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