LeishMANIAdb
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RNA binding protein rggm

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
RNA binding protein rggm
Gene product:
MRB1-associated protein, putative
Species:
Leishmania braziliensis
UniProt:
A4HJ16_LEIBR
TriTrypDb:
LbrM.33.0260 * , LBRM2903_310012100 *
Length:
183

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 3
NetGPI no yes: 0, no: 3
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HJ16
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HJ16

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0003676 nucleic acid binding 3 4
GO:0003723 RNA binding 4 4
GO:0005488 binding 1 4
GO:0097159 organic cyclic compound binding 2 4
GO:1901363 heterocyclic compound binding 2 4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 149 153 PF00656 0.417
CLV_NRD_NRD_1 144 146 PF00675 0.455
CLV_NRD_NRD_1 157 159 PF00675 0.413
CLV_NRD_NRD_1 166 168 PF00675 0.438
CLV_NRD_NRD_1 42 44 PF00675 0.495
CLV_NRD_NRD_1 6 8 PF00675 0.541
CLV_PCSK_KEX2_1 144 146 PF00082 0.468
CLV_PCSK_KEX2_1 166 168 PF00082 0.441
CLV_PCSK_KEX2_1 42 44 PF00082 0.495
CLV_PCSK_KEX2_1 6 8 PF00082 0.541
CLV_PCSK_PC7_1 2 8 PF00082 0.541
CLV_PCSK_SKI1_1 114 118 PF00082 0.214
DEG_Nend_UBRbox_1 1 4 PF02207 0.537
DOC_MAPK_gen_1 132 141 PF00069 0.405
DOC_MAPK_gen_1 42 49 PF00069 0.485
DOC_PP4_FxxP_1 106 109 PF00568 0.414
DOC_PP4_FxxP_1 37 40 PF00568 0.483
LIG_deltaCOP1_diTrp_1 26 37 PF00928 0.552
LIG_FHA_1 126 132 PF00498 0.414
LIG_FHA_1 136 142 PF00498 0.427
LIG_FHA_2 48 54 PF00498 0.444
LIG_FHA_2 78 84 PF00498 0.414
LIG_LIR_Apic_2 105 109 PF02991 0.414
LIG_LIR_Apic_2 36 40 PF02991 0.481
LIG_LIR_Gen_1 75 85 PF02991 0.414
LIG_LIR_Gen_1 90 97 PF02991 0.414
LIG_LIR_Nem_3 75 81 PF02991 0.420
LIG_LIR_Nem_3 90 96 PF02991 0.433
LIG_Pex14_2 93 97 PF04695 0.424
LIG_SH2_STAT5 130 133 PF00017 0.369
LIG_SUMO_SIM_par_1 136 143 PF11976 0.478
LIG_SUMO_SIM_par_1 45 50 PF11976 0.478
MOD_CK1_1 177 183 PF00069 0.512
MOD_CK1_1 70 76 PF00069 0.414
MOD_CK2_1 119 125 PF00069 0.463
MOD_CK2_1 47 53 PF00069 0.459
MOD_GlcNHglycan 11 14 PF01048 0.555
MOD_GlcNHglycan 179 182 PF01048 0.475
MOD_GlcNHglycan 69 72 PF01048 0.214
MOD_GlcNHglycan 97 100 PF01048 0.272
MOD_GSK3_1 70 77 PF00069 0.421
MOD_NEK2_1 1 6 PF00069 0.623
MOD_NEK2_1 140 145 PF00069 0.535
MOD_NEK2_1 47 52 PF00069 0.462
MOD_PKA_2 1 7 PF00069 0.559
MOD_PKB_1 7 15 PF00069 0.545
MOD_Plk_1 135 141 PF00069 0.426
MOD_Plk_1 73 79 PF00069 0.414
MOD_Plk_1 89 95 PF00069 0.414
MOD_Plk_4 125 131 PF00069 0.414
MOD_Plk_4 135 141 PF00069 0.426
TRG_DiLeu_BaEn_1 136 141 PF01217 0.423
TRG_ER_diArg_1 155 158 PF00400 0.414
TRG_ER_diArg_1 165 167 PF00400 0.431
TRG_ER_diArg_1 41 43 PF00400 0.494
TRG_ER_diArg_1 5 7 PF00400 0.549
TRG_Pf-PMV_PEXEL_1 114 118 PF00026 0.214
TRG_Pf-PMV_PEXEL_1 145 149 PF00026 0.451

Homologs

Protein Taxonomy Sequence identity Coverage
A0A422NG79 Trypanosoma rangeli 80% 100%
A4HL62 Leishmania braziliensis 99% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS