Putative calpain-like cysteine peptidase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Calpain-like protein 2

Species:

Leishmania braziliensis

UniProt:

A4HJ14_LEIBR

TriTrypDb:

LbrM.31.0510 , LBRM2903_310011600

Length:

783

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 1
Forrest at al. (metacyclic)	no	yes: 3
Forrest at al. (procyclic)	no	yes: 4
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 36

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 16

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 20

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 2, no: 104
NetGPI	no	yes: 0, no: 106

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	3
GO:0110165	cellular anatomical entity	1	5
GO:0005815	microtubule organizing center	2	1
GO:0005856	cytoskeleton	5	1
GO:0020016	ciliary pocket	2	1
GO:0020038	subpellicular network	2	1
GO:0030863	cortical cytoskeleton	6	1
GO:0036064	ciliary basal body	3	1
GO:0043226	organelle	2	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0005930	axoneme	2	1
GO:0016020	membrane	2	1

Expansion

Sequence features

A4HJ14

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HJ14

Function

Biological processes
Term	Name	Level	Count
GO:0006508	proteolysis	4	107
GO:0006807	nitrogen compound metabolic process	2	107
GO:0008152	metabolic process	1	107
GO:0019538	protein metabolic process	3	107
GO:0043170	macromolecule metabolic process	3	107
GO:0044238	primary metabolic process	2	107
GO:0071704	organic substance metabolic process	2	107
GO:1901564	organonitrogen compound metabolic process	3	107

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	107
GO:0004175	endopeptidase activity	4	107
GO:0004197	cysteine-type endopeptidase activity	5	107
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	6	107
GO:0008233	peptidase activity	3	107
GO:0008234	cysteine-type peptidase activity	4	107
GO:0016787	hydrolase activity	2	107
GO:0140096	catalytic activity, acting on a protein	2	107

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	575	579	PF00656	0.569
CLV_C14_Caspase3-7	61	65	PF00656	0.450
CLV_C14_Caspase3-7	655	659	PF00656	0.463
CLV_NRD_NRD_1	310	312	PF00675	0.276
CLV_NRD_NRD_1	401	403	PF00675	0.343
CLV_NRD_NRD_1	73	75	PF00675	0.549
CLV_PCSK_FUR_1	106	110	PF00082	0.666
CLV_PCSK_KEX2_1	108	110	PF00082	0.641
CLV_PCSK_KEX2_1	218	220	PF00082	0.455
CLV_PCSK_KEX2_1	310	312	PF00082	0.280
CLV_PCSK_KEX2_1	401	403	PF00082	0.335
CLV_PCSK_KEX2_1	546	548	PF00082	0.312
CLV_PCSK_KEX2_1	727	729	PF00082	0.507
CLV_PCSK_KEX2_1	73	75	PF00082	0.529
CLV_PCSK_PC1ET2_1	108	110	PF00082	0.629
CLV_PCSK_PC1ET2_1	218	220	PF00082	0.418
CLV_PCSK_PC1ET2_1	546	548	PF00082	0.321
CLV_PCSK_PC1ET2_1	727	729	PF00082	0.522
CLV_PCSK_SKI1_1	136	140	PF00082	0.355
CLV_PCSK_SKI1_1	219	223	PF00082	0.579
CLV_PCSK_SKI1_1	311	315	PF00082	0.321
CLV_PCSK_SKI1_1	48	52	PF00082	0.621
CLV_PCSK_SKI1_1	670	674	PF00082	0.498
DEG_MDM2_SWIB_1	572	580	PF02201	0.489
DEG_SCF_FBW7_1	137	143	PF00400	0.213
DEG_SCF_FBW7_2	125	130	PF00400	0.216
DOC_CKS1_1	137	142	PF01111	0.232
DOC_CKS1_1	38	43	PF01111	0.659
DOC_CKS1_1	472	477	PF01111	0.499
DOC_CKS1_1	591	596	PF01111	0.470
DOC_CKS1_1	757	762	PF01111	0.429
DOC_MAPK_gen_1	401	407	PF00069	0.516
DOC_MAPK_MEF2A_6	152	159	PF00069	0.262
DOC_MAPK_MEF2A_6	706	714	PF00069	0.408
DOC_MIT_MIM_1	517	528	PF04212	0.394
DOC_PIKK_1	227	234	PF02985	0.536
DOC_PP1_RVXF_1	668	675	PF00149	0.441
DOC_PP1_RVXF_1	721	727	PF00149	0.375
DOC_PP2B_LxvP_1	76	79	PF13499	0.539
DOC_PP4_FxxP_1	347	350	PF00568	0.512
DOC_PP4_FxxP_1	694	697	PF00568	0.297
DOC_USP7_MATH_1	20	24	PF00917	0.737
DOC_USP7_UBL2_3	104	108	PF12436	0.661
DOC_USP7_UBL2_3	206	210	PF12436	0.333
DOC_USP7_UBL2_3	410	414	PF12436	0.505
DOC_USP7_UBL2_3	51	55	PF12436	0.650
DOC_USP7_UBL2_3	546	550	PF12436	0.529
DOC_USP7_UBL2_3	723	727	PF12436	0.350
DOC_WW_Pin1_4	123	128	PF00397	0.374
DOC_WW_Pin1_4	136	141	PF00397	0.444
DOC_WW_Pin1_4	37	42	PF00397	0.630
DOC_WW_Pin1_4	471	476	PF00397	0.512
DOC_WW_Pin1_4	561	566	PF00397	0.544
DOC_WW_Pin1_4	590	595	PF00397	0.496
DOC_WW_Pin1_4	688	693	PF00397	0.360
DOC_WW_Pin1_4	756	761	PF00397	0.411
LIG_14-3-3_CanoR_1	293	298	PF00244	0.514
LIG_14-3-3_CanoR_1	348	358	PF00244	0.517
LIG_APCC_ABBAyCdc20_2	219	225	PF00400	0.559
LIG_BIR_II_1	1	5	PF00653	0.527
LIG_BIR_III_4	337	341	PF00653	0.574
LIG_BRCT_BRCA1_1	690	694	PF00533	0.431
LIG_CSL_BTD_1	296	299	PF09270	0.545
LIG_CSL_BTD_1	374	377	PF09270	0.558
LIG_deltaCOP1_diTrp_1	536	541	PF00928	0.502
LIG_deltaCOP1_diTrp_1	575	583	PF00928	0.510
LIG_EH1_1	707	715	PF00400	0.305
LIG_eIF4E_1	498	504	PF01652	0.522
LIG_eIF4E_1	708	714	PF01652	0.272
LIG_FHA_1	178	184	PF00498	0.384
LIG_FHA_1	192	198	PF00498	0.378
LIG_FHA_1	324	330	PF00498	0.517
LIG_FHA_1	483	489	PF00498	0.531
LIG_FHA_1	591	597	PF00498	0.494
LIG_FHA_1	94	100	PF00498	0.557
LIG_FHA_2	438	444	PF00498	0.478
LIG_FHA_2	472	478	PF00498	0.461
LIG_FHA_2	749	755	PF00498	0.472
LIG_Integrin_RGD_1	424	426	PF01839	0.192
LIG_LIR_Apic_2	345	350	PF02991	0.504
LIG_LIR_Apic_2	691	697	PF02991	0.359
LIG_LIR_Gen_1	409	420	PF02991	0.511
LIG_LIR_Gen_1	440	449	PF02991	0.500
LIG_LIR_Gen_1	454	463	PF02991	0.517
LIG_LIR_Gen_1	495	505	PF02991	0.539
LIG_LIR_Gen_1	515	525	PF02991	0.526
LIG_LIR_Gen_1	621	631	PF02991	0.426
LIG_LIR_Gen_1	637	648	PF02991	0.428
LIG_LIR_Nem_3	141	147	PF02991	0.311
LIG_LIR_Nem_3	220	226	PF02991	0.478
LIG_LIR_Nem_3	273	277	PF02991	0.515
LIG_LIR_Nem_3	409	415	PF02991	0.500
LIG_LIR_Nem_3	418	422	PF02991	0.505
LIG_LIR_Nem_3	432	437	PF02991	0.515
LIG_LIR_Nem_3	440	445	PF02991	0.517
LIG_LIR_Nem_3	515	520	PF02991	0.535
LIG_LIR_Nem_3	545	551	PF02991	0.475
LIG_LIR_Nem_3	593	598	PF02991	0.455
LIG_LIR_Nem_3	621	627	PF02991	0.424
LIG_LIR_Nem_3	637	643	PF02991	0.462
LIG_LIR_Nem_3	691	696	PF02991	0.329
LIG_LIR_Nem_3	725	729	PF02991	0.389
LIG_LYPXL_yS_3	551	554	PF13949	0.457
LIG_MLH1_MIPbox_1	690	694	PF16413	0.439
LIG_MYND_1	43	47	PF01753	0.679
LIG_Pex14_2	371	375	PF04695	0.556
LIG_Pex14_2	572	576	PF04695	0.497
LIG_PTB_Apo_2	553	560	PF02174	0.521
LIG_PTB_Phospho_1	553	559	PF10480	0.406
LIG_SH2_CRK	412	416	PF00017	0.499
LIG_SH2_CRK	419	423	PF00017	0.501
LIG_SH2_CRK	509	513	PF00017	0.515
LIG_SH2_CRK	640	644	PF00017	0.420
LIG_SH2_CRK	684	688	PF00017	0.475
LIG_SH2_GRB2like	146	149	PF00017	0.391
LIG_SH2_GRB2like	419	422	PF00017	0.491
LIG_SH2_GRB2like	80	83	PF00017	0.540
LIG_SH2_NCK_1	419	423	PF00017	0.516
LIG_SH2_PTP2	17	20	PF00017	0.773
LIG_SH2_PTP2	624	627	PF00017	0.454
LIG_SH2_PTP2	69	72	PF00017	0.524
LIG_SH2_SRC	419	422	PF00017	0.474
LIG_SH2_SRC	69	72	PF00017	0.559
LIG_SH2_STAP1	153	157	PF00017	0.343
LIG_SH2_STAP1	419	423	PF00017	0.512
LIG_SH2_STAP1	442	446	PF00017	0.517
LIG_SH2_STAT5	17	20	PF00017	0.754
LIG_SH2_STAT5	176	179	PF00017	0.340
LIG_SH2_STAT5	256	259	PF00017	0.425
LIG_SH2_STAT5	264	267	PF00017	0.524
LIG_SH2_STAT5	284	287	PF00017	0.412
LIG_SH2_STAT5	327	330	PF00017	0.510
LIG_SH2_STAT5	468	471	PF00017	0.531
LIG_SH2_STAT5	516	519	PF00017	0.502
LIG_SH2_STAT5	624	627	PF00017	0.402
LIG_SH2_STAT5	684	687	PF00017	0.400
LIG_SH2_STAT5	69	72	PF00017	0.537
LIG_SH2_STAT5	693	696	PF00017	0.373
LIG_SH2_STAT5	708	711	PF00017	0.375
LIG_SH2_STAT5	717	720	PF00017	0.376
LIG_SH2_STAT5	80	83	PF00017	0.512
LIG_SH3_1	424	430	PF00018	0.392
LIG_SH3_2	22	27	PF14604	0.764
LIG_SH3_2	565	570	PF14604	0.392
LIG_SH3_3	134	140	PF00018	0.520
LIG_SH3_3	185	191	PF00018	0.350
LIG_SH3_3	19	25	PF00018	0.783
LIG_SH3_3	33	39	PF00018	0.648
LIG_SH3_3	424	430	PF00018	0.471
LIG_SH3_3	562	568	PF00018	0.565
LIG_SH3_3	614	620	PF00018	0.405
LIG_SH3_3	662	668	PF00018	0.492
LIG_SH3_3	701	707	PF00018	0.524
LIG_SH3_3	757	763	PF00018	0.406
LIG_SH3_3	8	14	PF00018	0.701
LIG_SH3_4	667	674	PF00018	0.315
LIG_SH3_5	594	598	PF00018	0.442
LIG_SUMO_SIM_par_1	376	382	PF11976	0.494
LIG_TYR_ITIM	221	226	PF00017	0.327
LIG_TYR_ITIM	638	643	PF00017	0.486
LIG_TYR_ITIM	682	687	PF00017	0.276
LIG_UBA3_1	98	104	PF00899	0.389
LIG_WRC_WIRS_1	442	447	PF05994	0.401
LIG_WRC_WIRS_1	739	744	PF05994	0.483
LIG_WW_1	14	17	PF00397	0.768
LIG_WW_1	77	80	PF00397	0.568
LIG_WW_3	70	74	PF00397	0.592
MOD_CDK_SPK_2	756	761	PF00069	0.552
MOD_CK1_1	23	29	PF00069	0.732
MOD_CK1_1	316	322	PF00069	0.358
MOD_CK1_1	432	438	PF00069	0.375
MOD_CK1_1	535	541	PF00069	0.413
MOD_CK1_1	618	624	PF00069	0.496
MOD_CK2_1	437	443	PF00069	0.360
MOD_CK2_1	493	499	PF00069	0.362
MOD_CK2_1	660	666	PF00069	0.422
MOD_CK2_1	748	754	PF00069	0.510
MOD_CMANNOS	573	576	PF00535	0.343
MOD_Cter_Amidation	651	654	PF01082	0.574
MOD_DYRK1A_RPxSP_1	37	41	PF00069	0.754
MOD_GlcNHglycan	182	186	PF01048	0.351
MOD_GlcNHglycan	198	201	PF01048	0.325
MOD_GlcNHglycan	207	210	PF01048	0.424
MOD_GlcNHglycan	329	332	PF01048	0.314
MOD_GlcNHglycan	351	354	PF01048	0.381
MOD_GlcNHglycan	488	491	PF01048	0.409
MOD_GlcNHglycan	495	498	PF01048	0.393
MOD_GlcNHglycan	583	586	PF01048	0.378
MOD_GlcNHglycan	617	620	PF01048	0.576
MOD_GlcNHglycan	650	653	PF01048	0.442
MOD_GSK3_1	136	143	PF00069	0.435
MOD_GSK3_1	177	184	PF00069	0.392
MOD_GSK3_1	192	199	PF00069	0.354
MOD_GSK3_1	272	279	PF00069	0.334
MOD_GSK3_1	319	326	PF00069	0.328
MOD_GSK3_1	437	444	PF00069	0.353
MOD_GSK3_1	482	489	PF00069	0.391
MOD_GSK3_1	546	553	PF00069	0.332
MOD_GSK3_1	90	97	PF00069	0.524
MOD_N-GLC_1	147	152	PF02516	0.353
MOD_N-GLC_1	532	537	PF02516	0.373
MOD_N-GLC_1	615	620	PF02516	0.446
MOD_N-GLC_1	674	679	PF02516	0.417
MOD_N-GLC_1	99	104	PF02516	0.521
MOD_N-GLC_2	556	558	PF02516	0.448
MOD_NEK2_1	183	188	PF00069	0.414
MOD_NEK2_1	205	210	PF00069	0.427
MOD_NEK2_1	408	413	PF00069	0.350
MOD_NEK2_1	482	487	PF00069	0.316
MOD_NEK2_1	643	648	PF00069	0.348
MOD_NEK2_1	657	662	PF00069	0.467
MOD_NEK2_1	682	687	PF00069	0.403
MOD_NEK2_1	713	718	PF00069	0.394
MOD_NEK2_1	748	753	PF00069	0.535
MOD_NEK2_2	272	277	PF00069	0.388
MOD_NEK2_2	452	457	PF00069	0.504
MOD_PIKK_1	313	319	PF00454	0.396
MOD_PIKK_1	625	631	PF00454	0.429
MOD_PIKK_1	740	746	PF00454	0.612
MOD_PK_1	550	556	PF00069	0.360
MOD_PKA_1	546	552	PF00069	0.426
MOD_PKA_2	23	29	PF00069	0.703
MOD_PKA_2	292	298	PF00069	0.281
MOD_PKA_2	546	552	PF00069	0.410
MOD_PKA_2	648	654	PF00069	0.466
MOD_Plk_1	272	278	PF00069	0.329
MOD_Plk_1	408	414	PF00069	0.464
MOD_Plk_1	452	458	PF00069	0.433
MOD_Plk_1	568	574	PF00069	0.363
MOD_Plk_1	90	96	PF00069	0.469
MOD_Plk_2-3	246	252	PF00069	0.416
MOD_Plk_2-3	459	465	PF00069	0.193
MOD_Plk_2-3	634	640	PF00069	0.523
MOD_Plk_2-3	90	96	PF00069	0.454
MOD_Plk_4	140	146	PF00069	0.419
MOD_Plk_4	183	189	PF00069	0.365
MOD_Plk_4	272	278	PF00069	0.378
MOD_Plk_4	280	286	PF00069	0.380
MOD_Plk_4	293	299	PF00069	0.332
MOD_Plk_4	323	329	PF00069	0.368
MOD_Plk_4	441	447	PF00069	0.358
MOD_Plk_4	452	458	PF00069	0.317
MOD_Plk_4	643	649	PF00069	0.408
MOD_Plk_4	660	666	PF00069	0.513
MOD_Plk_4	682	688	PF00069	0.468
MOD_Plk_4	713	719	PF00069	0.452
MOD_Plk_4	94	100	PF00069	0.600
MOD_ProDKin_1	123	129	PF00069	0.374
MOD_ProDKin_1	136	142	PF00069	0.444
MOD_ProDKin_1	37	43	PF00069	0.629
MOD_ProDKin_1	471	477	PF00069	0.362
MOD_ProDKin_1	561	567	PF00069	0.407
MOD_ProDKin_1	590	596	PF00069	0.491
MOD_ProDKin_1	688	694	PF00069	0.356
MOD_ProDKin_1	756	762	PF00069	0.417
MOD_SUMO_for_1	722	725	PF00179	0.386
MOD_SUMO_rev_2	245	254	PF00179	0.581
MOD_SUMO_rev_2	84	94	PF00179	0.597
TRG_DiLeu_BaEn_1	193	198	PF01217	0.424
TRG_DiLeu_BaEn_1	499	504	PF01217	0.428
TRG_DiLeu_BaEn_1	639	644	PF01217	0.510
TRG_DiLeu_BaLyEn_6	520	525	PF01217	0.424
TRG_ENDOCYTIC_2	223	226	PF00928	0.438
TRG_ENDOCYTIC_2	412	415	PF00928	0.351
TRG_ENDOCYTIC_2	419	422	PF00928	0.350
TRG_ENDOCYTIC_2	442	445	PF00928	0.380
TRG_ENDOCYTIC_2	463	466	PF00928	0.403
TRG_ENDOCYTIC_2	468	471	PF00928	0.353
TRG_ENDOCYTIC_2	498	501	PF00928	0.357
TRG_ENDOCYTIC_2	509	512	PF00928	0.376
TRG_ENDOCYTIC_2	551	554	PF00928	0.293
TRG_ENDOCYTIC_2	624	627	PF00928	0.421
TRG_ENDOCYTIC_2	640	643	PF00928	0.396
TRG_ENDOCYTIC_2	684	687	PF00928	0.409
TRG_ENDOCYTIC_2	693	696	PF00928	0.356
TRG_ER_diArg_1	309	311	PF00400	0.371
TRG_ER_diArg_1	400	402	PF00400	0.379
TRG_ER_diArg_1	525	528	PF00400	0.391
TRG_ER_diArg_1	598	601	PF00400	0.337
TRG_ER_diArg_1	72	74	PF00400	0.643
TRG_NES_CRM1_1	429	443	PF08389	0.360
TRG_Pf-PMV_PEXEL_1	57	62	PF00026	0.640

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8T6	Leptomonas seymouri	32%	100%
A0A0N1I8N2	Leptomonas seymouri	31%	79%
A0A0N1IGQ2	Leptomonas seymouri	32%	100%
A0A0N1ILF1	Leptomonas seymouri	34%	100%
A0A0N1IMH1	Leptomonas seymouri	83%	100%
A0A0N1P9P1	Leptomonas seymouri	32%	92%
A0A0N1PCA9	Leptomonas seymouri	33%	100%
A0A0N1PE91	Leptomonas seymouri	26%	88%
A0A0N1PFI4	Leptomonas seymouri	32%	100%
A0A0S4JLK6	Bodo saltans	27%	96%
A0A0S4JS70	Bodo saltans	26%	100%
A0A0S4KGT2	Bodo saltans	40%	100%
A0A1X0NJ61	Trypanosomatidae	31%	100%
A0A1X0NJK2	Trypanosomatidae	30%	100%
A0A1X0NJX8	Trypanosomatidae	60%	100%
A0A1X0NKT7	Trypanosomatidae	37%	98%
A0A1X0NKX8	Trypanosomatidae	33%	96%
A0A1X0NMT3	Trypanosomatidae	31%	92%
A0A1X0NW84	Trypanosomatidae	33%	100%
A0A1X0NW85	Trypanosomatidae	32%	100%
A0A1X0NW89	Trypanosomatidae	36%	91%
A0A1X0NWA6	Trypanosomatidae	25%	90%
A0A1X0NWW1	Trypanosomatidae	36%	100%
A0A3Q8IBS3	Leishmania donovani	34%	86%
A0A3Q8IDD4	Leishmania donovani	33%	100%
A0A3Q8IJT4	Leishmania donovani	28%	100%
A0A3S5H5A5	Leishmania donovani	30%	92%
A0A3S5ISG2	Trypanosoma rangeli	32%	100%
A0A3S7WW13	Leishmania donovani	26%	71%
A0A3S7WW18	Leishmania donovani	34%	95%
A0A3S7WW41	Leishmania donovani	30%	100%
A0A3S7WW71	Leishmania donovani	34%	100%
A0A3S7X430	Leishmania donovani	92%	100%
A0A3S7X438	Leishmania donovani	33%	83%
A0A3S7X460	Leishmania donovani	32%	100%
A0A3S7X463	Leishmania donovani	29%	84%
A0A3S7X470	Leishmania donovani	29%	100%
A0A422MYU1	Trypanosoma rangeli	37%	85%
A0A422MYX0	Trypanosoma rangeli	35%	100%
A4H3W4	Leishmania braziliensis	31%	100%
A4HE81	Leishmania braziliensis	32%	100%
A4HFH7	Leishmania braziliensis	24%	100%
A4HJ21	Leishmania braziliensis	28%	88%
A4HJ22	Leishmania braziliensis	33%	83%
A4HJ24	Leishmania braziliensis	33%	100%
A4HS39	Leishmania infantum	30%	92%
A4HYN0	Leishmania infantum	34%	95%
A4HYW1	Leishmania infantum	34%	77%
A4HYW2	Leishmania infantum	34%	100%
A4HYW3	Leishmania infantum	30%	100%
A4HYW4	Leishmania infantum	26%	78%
A4I1J4	Leishmania infantum	33%	100%
A4I6E4	Leishmania infantum	29%	100%
A4I6E6	Leishmania infantum	32%	100%
A4I6F0	Leishmania infantum	33%	83%
A4I6K4	Leishmania infantum	92%	100%
A4I6K5	Leishmania infantum	29%	84%
A4I6K6	Leishmania infantum	28%	100%
C9ZIE7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	73%
C9ZIE8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%
C9ZIE9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	100%
C9ZN52	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	53%	99%
C9ZN53	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	92%
C9ZWY4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	97%
C9ZY36	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	91%
E8NHG6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	100%
E8NHG7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	83%
E8NHG8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	100%
E8NHM2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	100%
E8NHM4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	100%
E8NHM8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	100%
E9AIH1	Leishmania braziliensis	35%	96%
E9AIH3	Leishmania braziliensis	35%	100%
E9AIH4	Leishmania braziliensis	30%	100%
E9AIH6	Leishmania braziliensis	29%	100%
E9AK26	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	98%
E9AUQ7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	84%
E9AUQ9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	100%
E9AUR0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	100%
E9AUR1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9AXM9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	100%
E9B1J0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
E9B1J1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	84%
E9B1J2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	100%
E9B1J6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	100%
Q4Q6L7	Leishmania major	33%	100%
Q4Q6L9	Leishmania major	29%	100%
Q4Q6M0	Leishmania major	35%	100%
Q4Q6M2	Leishmania major	28%	100%
Q4Q6M3	Leishmania major	30%	100%
Q4Q6M4	Leishmania major	92%	100%
Q4Q9U3	Leishmania major	33%	100%
Q4QCS6	Leishmania major	30%	100%
Q4QCS7	Leishmania major	34%	100%
Q4QCS8	Leishmania major	34%	100%
Q4QCS9	Leishmania major	34%	100%
Q9U0T9	Leishmania major	33%	100%
Q9VT65	Drosophila melanogaster	23%	85%
V5AYJ1	Trypanosoma cruzi	33%	100%
V5B5I4	Trypanosoma cruzi	36%	94%
V5BA05	Trypanosoma cruzi	37%	100%
V5BEL3	Trypanosoma cruzi	32%	100%
V5BN20	Trypanosoma cruzi	59%	100%
V5D5V8	Trypanosoma cruzi	28%	100%
V5D9Y2	Trypanosoma cruzi	31%	92%
V5DES7	Trypanosoma cruzi	32%	99%