Tick transposon

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Tick transposon

Gene product:

2OG-Fe(II) oxygenase superfamily, putative

Species:

Leishmania braziliensis

UniProt:

A4HJ01_LEIBR

TriTrypDb:

LbrM.31.0380 , LBRM2903_310010400

Length:

200

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HJ01

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HJ01

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	131	133	PF00675	0.596
CLV_NRD_NRD_1	48	50	PF00675	0.660
CLV_PCSK_KEX2_1	131	133	PF00082	0.596
CLV_PCSK_SKI1_1	124	128	PF00082	0.538
CLV_PCSK_SKI1_1	137	141	PF00082	0.328
CLV_PCSK_SKI1_1	188	192	PF00082	0.590
CLV_PCSK_SKI1_1	87	91	PF00082	0.539
DEG_APCC_DBOX_1	86	94	PF00400	0.559
DOC_CDC14_PxL_1	55	63	PF14671	0.490
DOC_MAPK_gen_1	123	129	PF00069	0.536
DOC_PP1_RVXF_1	135	142	PF00149	0.469
DOC_PP2B_LxvP_1	177	180	PF13499	0.511
DOC_PP4_FxxP_1	60	63	PF00568	0.425
DOC_USP7_MATH_1	28	32	PF00917	0.556
DOC_USP7_UBL2_3	12	16	PF12436	0.537
DOC_USP7_UBL2_3	145	149	PF12436	0.516
LIG_14-3-3_CanoR_1	131	136	PF00244	0.554
LIG_14-3-3_CanoR_1	38	44	PF00244	0.637
LIG_14-3-3_CanoR_1	49	53	PF00244	0.497
LIG_14-3-3_CanoR_1	64	68	PF00244	0.527
LIG_Actin_WH2_2	115	133	PF00022	0.636
LIG_FHA_1	158	164	PF00498	0.546
LIG_FHA_1	63	69	PF00498	0.595
LIG_FHA_1	71	77	PF00498	0.555
LIG_FHA_1	8	14	PF00498	0.548
LIG_FHA_2	107	113	PF00498	0.491
LIG_LIR_Apic_2	147	151	PF02991	0.576
LIG_LIR_Nem_3	113	119	PF02991	0.625
LIG_LIR_Nem_3	138	144	PF02991	0.469
LIG_MYND_1	59	63	PF01753	0.605
LIG_NRBOX	173	179	PF00104	0.628
LIG_Rb_LxCxE_1	101	113	PF01857	0.530
LIG_SH2_CRK	148	152	PF00017	0.504
LIG_SH2_CRK	55	59	PF00017	0.496
LIG_SH2_STAT5	99	102	PF00017	0.493
LIG_SUMO_SIM_par_1	2	8	PF11976	0.610
LIG_TYR_ITIM	53	58	PF00017	0.509
LIG_UBA3_1	89	95	PF00899	0.509
LIG_WRC_WIRS_1	126	131	PF05994	0.505
MOD_CK1_1	157	163	PF00069	0.478
MOD_CK1_1	31	37	PF00069	0.615
MOD_GlcNHglycan	156	159	PF01048	0.575
MOD_GlcNHglycan	33	36	PF01048	0.526
MOD_GSK3_1	104	111	PF00069	0.519
MOD_GSK3_1	131	138	PF00069	0.484
MOD_GSK3_1	30	37	PF00069	0.523
MOD_GSK3_1	39	46	PF00069	0.561
MOD_NEK2_1	130	135	PF00069	0.532
MOD_NEK2_1	22	27	PF00069	0.344
MOD_NEK2_1	48	53	PF00069	0.629
MOD_NEK2_1	7	12	PF00069	0.555
MOD_PIKK_1	28	34	PF00454	0.618
MOD_PIKK_1	39	45	PF00454	0.522
MOD_PKA_1	131	137	PF00069	0.482
MOD_PKA_2	130	136	PF00069	0.597
MOD_PKA_2	39	45	PF00069	0.650
MOD_PKA_2	48	54	PF00069	0.509
MOD_PKA_2	63	69	PF00069	0.525
MOD_Plk_1	104	110	PF00069	0.485
MOD_Plk_4	125	131	PF00069	0.513
MOD_Plk_4	48	54	PF00069	0.614
MOD_Plk_4	63	69	PF00069	0.601
TRG_ENDOCYTIC_2	55	58	PF00928	0.493
TRG_ENDOCYTIC_2	99	102	PF00928	0.502
TRG_ER_diArg_1	130	132	PF00400	0.580
TRG_NES_CRM1_1	3	17	PF08389	0.570
TRG_Pf-PMV_PEXEL_1	188	192	PF00026	0.496

Homologs


Protein	Taxonomy	Sequence identity	Coverage
E9B1H8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	63%	100%