Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HIZ7_LEIBR

TriTrypDb:

LbrM.31.0330 , LBRM2903_310010000

Length:

206

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HIZ7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HIZ7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	127	129	PF00675	0.674
CLV_NRD_NRD_1	164	166	PF00675	0.694
CLV_PCSK_KEX2_1	127	129	PF00082	0.674
CLV_PCSK_KEX2_1	164	166	PF00082	0.694
CLV_PCSK_SKI1_1	140	144	PF00082	0.685
DEG_Nend_UBRbox_2	1	3	PF02207	0.811
DEG_SCF_FBW7_1	197	204	PF00400	0.492
DOC_CKS1_1	105	110	PF01111	0.477
DOC_CKS1_1	198	203	PF01111	0.687
DOC_MAPK_gen_1	17	26	PF00069	0.581
DOC_USP7_MATH_1	185	189	PF00917	0.712
DOC_USP7_MATH_1	201	205	PF00917	0.506
DOC_USP7_MATH_1	40	44	PF00917	0.697
DOC_USP7_MATH_1	84	88	PF00917	0.556
DOC_WW_Pin1_4	104	109	PF00397	0.435
DOC_WW_Pin1_4	197	202	PF00397	0.676
DOC_WW_Pin1_4	47	52	PF00397	0.553
DOC_WW_Pin1_4	91	96	PF00397	0.540
LIG_Actin_WH2_2	149	166	PF00022	0.653
LIG_EVH1_1	99	103	PF00568	0.738
LIG_FHA_1	114	120	PF00498	0.645
LIG_FHA_1	145	151	PF00498	0.665
LIG_FHA_2	39	45	PF00498	0.747
LIG_FHA_2	53	59	PF00498	0.598
LIG_LIR_Apic_2	94	100	PF02991	0.503
LIG_LIR_Nem_3	118	123	PF02991	0.645
LIG_MYND_1	100	104	PF01753	0.757
LIG_NRP_CendR_1	205	206	PF00754	0.795
LIG_SH2_CRK	120	124	PF00017	0.660
LIG_SH2_CRK	97	101	PF00017	0.508
LIG_SH2_NCK_1	97	101	PF00017	0.508
LIG_SH3_1	97	103	PF00018	0.768
LIG_SH3_3	176	182	PF00018	0.713
LIG_SH3_3	184	190	PF00018	0.711
LIG_SH3_3	195	201	PF00018	0.547
LIG_SH3_3	97	103	PF00018	0.741
LIG_TRAF2_1	66	69	PF00917	0.654
LIG_TRFH_1	97	101	PF08558	0.770
LIG_WW_2	100	103	PF00397	0.761
MOD_CDK_SPxK_1	104	110	PF00069	0.478
MOD_CK1_1	188	194	PF00069	0.623
MOD_CK2_1	24	30	PF00069	0.784
MOD_CK2_1	50	56	PF00069	0.559
MOD_GSK3_1	188	195	PF00069	0.622
MOD_GSK3_1	197	204	PF00069	0.560
MOD_GSK3_1	38	45	PF00069	0.668
MOD_GSK3_1	46	53	PF00069	0.685
MOD_GSK3_1	91	98	PF00069	0.533
MOD_NEK2_1	163	168	PF00069	0.427
MOD_PKA_2	163	169	PF00069	0.667
MOD_PKA_2	185	191	PF00069	0.560
MOD_Plk_4	192	198	PF00069	0.562
MOD_ProDKin_1	104	110	PF00069	0.432
MOD_ProDKin_1	197	203	PF00069	0.681
MOD_ProDKin_1	47	53	PF00069	0.554
MOD_ProDKin_1	91	97	PF00069	0.536
TRG_ENDOCYTIC_2	120	123	PF00928	0.651
TRG_ER_diArg_1	126	128	PF00400	0.579
TRG_ER_diArg_1	163	165	PF00400	0.679

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IIB3	Leishmania donovani	72%	100%
A4I6B4	Leishmania infantum	72%	100%
E9B1H0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	70%	100%
E9B1H2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	70%	88%
Q4Q6P2	Leishmania major	71%	100%