LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Protoglobin domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Protoglobin domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HIZ3_LEIBR
TriTrypDb:
LbrM.31.0290 , LBRM2903_310009500 *
Length:
157

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HIZ3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HIZ3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_KEX2_1 33 35 PF00082 0.625
CLV_PCSK_PC1ET2_1 33 35 PF00082 0.625
CLV_PCSK_SKI1_1 30 34 PF00082 0.560
DEG_Nend_UBRbox_2 1 3 PF02207 0.665
DOC_MAPK_gen_1 141 150 PF00069 0.472
LIG_14-3-3_CanoR_1 23 31 PF00244 0.680
LIG_eIF4E_1 129 135 PF01652 0.675
LIG_FHA_1 104 110 PF00498 0.560
LIG_FHA_1 123 129 PF00498 0.532
LIG_FHA_1 33 39 PF00498 0.611
LIG_FHA_1 90 96 PF00498 0.625
LIG_FHA_2 38 44 PF00498 0.631
LIG_LIR_Gen_1 22 32 PF02991 0.594
LIG_LIR_Nem_3 22 27 PF02991 0.485
LIG_LIR_Nem_3 77 82 PF02991 0.649
LIG_LIR_Nem_3 92 96 PF02991 0.501
LIG_PCNA_PIPBox_1 1 10 PF02747 0.654
LIG_SH2_PTP2 16 19 PF00017 0.424
LIG_SH2_SRC 72 75 PF00017 0.678
LIG_SH2_STAT5 16 19 PF00017 0.537
LIG_SH3_3 136 142 PF00018 0.586
LIG_UBA3_1 100 107 PF00899 0.480
LIG_UBA3_1 27 33 PF00899 0.611
MOD_CK1_1 122 128 PF00069 0.437
MOD_CK1_1 22 28 PF00069 0.687
MOD_CK2_1 49 55 PF00069 0.627
MOD_GlcNHglycan 121 124 PF01048 0.634
MOD_GlcNHglycan 24 27 PF01048 0.679
MOD_GlcNHglycan 51 54 PF01048 0.648
MOD_NEK2_1 134 139 PF00069 0.638
MOD_NEK2_1 8 13 PF00069 0.621
MOD_PIKK_1 32 38 PF00454 0.546
MOD_PKA_2 137 143 PF00069 0.628
MOD_PKA_2 22 28 PF00069 0.657
MOD_Plk_1 42 48 PF00069 0.663
MOD_Plk_1 8 14 PF00069 0.405
MOD_Plk_2-3 74 80 PF00069 0.644
MOD_Plk_4 74 80 PF00069 0.583
MOD_Plk_4 8 14 PF00069 0.560
TRG_DiLeu_BaLyEn_6 91 96 PF01217 0.663
TRG_ENDOCYTIC_2 16 19 PF00928 0.528
TRG_Pf-PMV_PEXEL_1 94 99 PF00026 0.604

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PDH9 Leptomonas seymouri 54% 100%
A0A1X0NJ16 Trypanosomatidae 37% 97%
A0A3R7MDS1 Trypanosoma rangeli 41% 96%
A0A3S7X442 Leishmania donovani 75% 100%
A4I6B0 Leishmania infantum 75% 100%
C9ZN37 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 39% 99%
E9B1G6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 73% 100%
Q4Q6P6 Leishmania major 70% 100%
V5BDZ3 Trypanosoma cruzi 41% 96%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS