LeishMANIAdb
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Paraflagellar rod protein 1D

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Paraflagellar rod protein 1D
Gene product:
paraflagellar rod protein 1D
Species:
Leishmania braziliensis
UniProt:
A4HIY0_LEIBR
TriTrypDb:
LbrM.31.0160 , LBRM2903_310005800
Length:
595

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 8
Forrest at al. (procyclic) no yes: 8
Silverman et al. no yes: 2
Pissara et al. yes yes: 28
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 8
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 24
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 46
NetGPI no yes: 0, no: 46
Cellular components
TermNameLevelCount
GO:0005737 cytoplasm 2 3
GO:0005929 cilium 4 47
GO:0005930 axoneme 2 1
GO:0031514 motile cilium 5 47
GO:0031974 membrane-enclosed lumen 2 3
GO:0031981 nuclear lumen 5 3
GO:0032838 plasma membrane bounded cell projection cytoplasm 4 3
GO:0042995 cell projection 2 47
GO:0043226 organelle 2 47
GO:0043227 membrane-bounded organelle 3 47
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Expansion

Sequence features

A4HIY0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HIY0

Function

Could not find GO biological_process term for this entry.
Molecular functions
TermNameLevelCount
GO:0005488 binding 1 47
GO:0005515 protein binding 2 47
GO:0005516 calmodulin binding 3 47
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 149 153 PF00656 0.494
CLV_C14_Caspase3-7 512 516 PF00656 0.390
CLV_NRD_NRD_1 13 15 PF00675 0.595
CLV_NRD_NRD_1 147 149 PF00675 0.476
CLV_NRD_NRD_1 270 272 PF00675 0.385
CLV_NRD_NRD_1 346 348 PF00675 0.392
CLV_NRD_NRD_1 357 359 PF00675 0.372
CLV_NRD_NRD_1 535 537 PF00675 0.376
CLV_PCSK_KEX2_1 147 149 PF00082 0.476
CLV_PCSK_KEX2_1 269 271 PF00082 0.354
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P2I5 Leptomonas seymouri 96% 100%
A0A0N0P5J5 Leptomonas seymouri 24% 75%
A0A0N1IFZ5 Leptomonas seymouri 65% 100%
A0A0S4IW44 Bodo saltans 29% 90%
A0A0S4IZY8 Bodo saltans 67% 100%
A0A0S4J013 Bodo saltans 29% 91%
A0A0S4J193 Bodo saltans 26% 96%
A0A0S4J561 Bodo saltans 28% 84%
A0A0S4JS20 Bodo saltans 86% 100%
A0A1X0NR57 Trypanosomatidae 24% 75%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS