WGS project CAEQ00000000 data, annotated contig

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HIX9_LEIBR

TriTrypDb:

LbrM.31.0150 , LBRM2903_310009200

Length:

323

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HIX9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HIX9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	18	20	PF00675	0.438
CLV_NRD_NRD_1	186	188	PF00675	0.549
CLV_NRD_NRD_1	241	243	PF00675	0.598
CLV_NRD_NRD_1	259	261	PF00675	0.539
CLV_NRD_NRD_1	283	285	PF00675	0.383
CLV_NRD_NRD_1	57	59	PF00675	0.435
CLV_NRD_NRD_1	61	63	PF00675	0.443
CLV_PCSK_KEX2_1	18	20	PF00082	0.446
CLV_PCSK_KEX2_1	186	188	PF00082	0.518
CLV_PCSK_KEX2_1	258	260	PF00082	0.555
CLV_PCSK_KEX2_1	57	59	PF00082	0.517
CLV_PCSK_KEX2_1	61	63	PF00082	0.519
CLV_PCSK_PC7_1	14	20	PF00082	0.533
CLV_PCSK_PC7_1	57	63	PF00082	0.551
CLV_PCSK_SKI1_1	134	138	PF00082	0.300
CLV_PCSK_SKI1_1	18	22	PF00082	0.430
CLV_PCSK_SKI1_1	187	191	PF00082	0.430
CLV_PCSK_SKI1_1	316	320	PF00082	0.498
CLV_Separin_Fungi	162	168	PF03568	0.364
DEG_APCC_DBOX_1	17	25	PF00400	0.445
DEG_APCC_DBOX_1	83	91	PF00400	0.399
DEG_Nend_UBRbox_1	1	4	PF02207	0.725
DOC_AGCK_PIF_1	249	254	PF00069	0.505
DOC_CKS1_1	67	72	PF01111	0.573
DOC_CYCLIN_RxL_1	14	25	PF00134	0.566
DOC_MAPK_gen_1	134	143	PF00069	0.452
DOC_MAPK_gen_1	18	26	PF00069	0.462
DOC_MAPK_gen_1	315	321	PF00069	0.467
DOC_PP1_RVXF_1	314	321	PF00149	0.524
DOC_PP4_FxxP_1	64	67	PF00568	0.578
DOC_USP7_MATH_1	113	117	PF00917	0.393
DOC_USP7_MATH_1	83	87	PF00917	0.434
DOC_WW_Pin1_4	242	247	PF00397	0.575
DOC_WW_Pin1_4	66	71	PF00397	0.543
LIG_14-3-3_CanoR_1	22	27	PF00244	0.442
LIG_14-3-3_CanoR_1	61	65	PF00244	0.557
LIG_14-3-3_CanoR_1	84	88	PF00244	0.294
LIG_Actin_WH2_2	41	59	PF00022	0.581
LIG_Actin_WH2_2	9	24	PF00022	0.503
LIG_AP2alpha_2	104	106	PF02296	0.327
LIG_BRCT_BRCA1_1	84	88	PF00533	0.426
LIG_deltaCOP1_diTrp_1	270	279	PF00928	0.581
LIG_eIF4E_1	109	115	PF01652	0.514
LIG_FHA_1	243	249	PF00498	0.511
LIG_FHA_1	30	36	PF00498	0.567
LIG_FHA_2	303	309	PF00498	0.520
LIG_LIR_Apic_2	46	52	PF02991	0.527
LIG_LIR_Apic_2	63	67	PF02991	0.443
LIG_LIR_Gen_1	173	181	PF02991	0.441
LIG_LIR_Gen_1	193	200	PF02991	0.384
LIG_LIR_Gen_1	233	241	PF02991	0.505
LIG_LIR_Gen_1	74	83	PF02991	0.395
LIG_LIR_Gen_1	95	101	PF02991	0.524
LIG_LIR_Nem_3	104	109	PF02991	0.438
LIG_LIR_Nem_3	173	177	PF02991	0.432
LIG_LIR_Nem_3	193	199	PF02991	0.380
LIG_LIR_Nem_3	233	239	PF02991	0.456
LIG_LIR_Nem_3	271	277	PF02991	0.557
LIG_LIR_Nem_3	74	80	PF02991	0.402
LIG_LIR_Nem_3	95	99	PF02991	0.506
LIG_SH2_CRK	17	21	PF00017	0.488
LIG_SH2_CRK	274	278	PF00017	0.600
LIG_SH2_STAT5	208	211	PF00017	0.453
LIG_SH3_3	64	70	PF00018	0.580
LIG_SUMO_SIM_anti_2	195	202	PF11976	0.420
LIG_SUMO_SIM_par_1	22	28	PF11976	0.505
LIG_TRAF2_1	153	156	PF00917	0.561
LIG_WRC_WIRS_1	171	176	PF05994	0.419
MOD_CK1_1	128	134	PF00069	0.520
MOD_CK1_1	195	201	PF00069	0.435
MOD_CK1_1	309	315	PF00069	0.429
MOD_CK1_1	71	77	PF00069	0.446
MOD_CK1_1	86	92	PF00069	0.473
MOD_CK2_1	150	156	PF00069	0.564
MOD_CK2_1	179	185	PF00069	0.483
MOD_CK2_1	22	28	PF00069	0.522
MOD_CK2_1	302	308	PF00069	0.455
MOD_GlcNHglycan	115	118	PF01048	0.334
MOD_GSK3_1	195	202	PF00069	0.396
MOD_GSK3_1	302	309	PF00069	0.489
MOD_GSK3_1	82	89	PF00069	0.493
MOD_N-GLC_1	230	235	PF02516	0.526
MOD_NEK2_1	199	204	PF00069	0.337
MOD_NEK2_2	230	235	PF00069	0.523
MOD_NEK2_2	83	88	PF00069	0.464
MOD_PIKK_1	125	131	PF00454	0.420
MOD_PIKK_1	268	274	PF00454	0.387
MOD_PIKK_1	279	285	PF00454	0.381
MOD_PIKK_1	29	35	PF00454	0.592
MOD_PIKK_1	43	49	PF00454	0.396
MOD_PK_1	22	28	PF00069	0.462
MOD_PK_1	306	312	PF00069	0.317
MOD_PKA_2	60	66	PF00069	0.556
MOD_PKA_2	83	89	PF00069	0.406
MOD_Plk_1	179	185	PF00069	0.490
MOD_Plk_1	192	198	PF00069	0.409
MOD_Plk_1	230	236	PF00069	0.546
MOD_Plk_2-3	159	165	PF00069	0.564
MOD_Plk_2-3	180	186	PF00069	0.538
MOD_Plk_4	170	176	PF00069	0.340
MOD_Plk_4	195	201	PF00069	0.392
MOD_Plk_4	223	229	PF00069	0.377
MOD_Plk_4	306	312	PF00069	0.463
MOD_Plk_4	83	89	PF00069	0.441
MOD_ProDKin_1	242	248	PF00069	0.564
MOD_ProDKin_1	66	72	PF00069	0.538
MOD_SUMO_rev_2	182	192	PF00179	0.563
TRG_DiLeu_BaEn_1	261	266	PF01217	0.550
TRG_ENDOCYTIC_2	109	112	PF00928	0.525
TRG_ENDOCYTIC_2	17	20	PF00928	0.436
TRG_ENDOCYTIC_2	254	257	PF00928	0.486
TRG_ENDOCYTIC_2	274	277	PF00928	0.594
TRG_ER_diArg_1	17	19	PF00400	0.469
TRG_ER_diArg_1	257	260	PF00400	0.541
TRG_ER_diArg_1	56	58	PF00400	0.514
TRG_ER_diArg_1	60	62	PF00400	0.512
TRG_NES_CRM1_1	148	164	PF08389	0.319
TRG_Pf-PMV_PEXEL_1	134	138	PF00026	0.300

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I1X3	Leptomonas seymouri	52%	100%
A0A1X0NJP2	Trypanosomatidae	26%	100%
A0A3S5H7P2	Leishmania donovani	76%	100%
A0A422N5I6	Trypanosoma rangeli	30%	99%
A4I6A7	Leishmania infantum	76%	100%
C9ZN34	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	100%
E9B1G3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	77%	100%
Q4Q6P9	Leishmania major	76%	100%
V5DEV4	Trypanosoma cruzi	29%	100%