LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HIX0_LEIBR
TriTrypDb:
LbrM.31.0060 , LBRM2903_310008200
Length:
133

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Cellular components
TermNameLevelCount
GO:0005737 cytoplasm 2 1
GO:0016020 membrane 2 9
GO:0110165 cellular anatomical entity 1 9
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Expansion

Sequence features

A4HIX0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HIX0

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 51 53 PF00675 0.419
CLV_PCSK_KEX2_1 51 53 PF00082 0.398
CLV_PCSK_PC7_1 47 53 PF00082 0.386
CLV_PCSK_SKI1_1 23 27 PF00082 0.425
CLV_PCSK_SKI1_1 79 83 PF00082 0.265
DEG_MDM2_SWIB_1 104 111 PF02201 0.442
DOC_CYCLIN_RxL_1 75 83 PF00134 0.593
DOC_MAPK_gen_1 75 84 PF00069 0.575
DOC_USP7_UBL2_3 23 27 PF12436 0.601
DOC_USP7_UBL2_3 75 79 PF12436 0.576
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PEH8 Leptomonas seymouri 89% 100%
A0A0S4JTI1 Bodo saltans 65% 100%
A0A1X0P7G0 Trypanosomatidae 77% 100%
A0A3Q8IIA2 Leishmania donovani 93% 100%
A4I699 Leishmania infantum 93% 100%
D0A540 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 77% 100%
E9B1F4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 92% 100%
Q4Q6Q8 Leishmania major 91% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS