Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HIV4_LEIBR

TriTrypDb:

LbrM.30.3710 , LBRM2903_300044500

Length:

442

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 7

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 7

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 12
NetGPI	no	yes: 0, no: 12

Show entries

Cellular components
Term	Name	Level	Count
GO:0005856	cytoskeleton	5	1
GO:0043226	organelle	2	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

A4HIV4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HIV4

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	198	202	PF00656	0.530
CLV_C14_Caspase3-7	227	231	PF00656	0.569
CLV_NRD_NRD_1	160	162	PF00675	0.377
CLV_NRD_NRD_1	177	179	PF00675	0.422
CLV_NRD_NRD_1	193	195	PF00675	0.528
CLV_NRD_NRD_1	246	248	PF00675	0.588
CLV_NRD_NRD_1	420	422	PF00675	0.539
CLV_NRD_NRD_1	61	63	PF00675	0.596
CLV_PCSK_KEX2_1	162	164	PF00082	0.468
CLV_PCSK_KEX2_1	192	194	PF00082	0.524

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1II28	Leptomonas seymouri	64%	100%
A0A0S4JDF0	Bodo saltans	26%	100%
A0A0S4JHV1	Bodo saltans	26%	72%
A0A1X0P1A4	Trypanosomatidae	40%	99%
A0A3Q8ISB1	Leishmania donovani	70%	100%
A0A422NMD4	Trypanosoma rangeli	36%	98%
A4I659	Leishmania infantum	71%	100%
C9ZRH9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	97%
E9B1E2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	70%	100%
Q4Q6S0	Leishmania major	69%	100%

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