Ribosomal protein L15

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ribosomal protein L15, putative

Species:

Leishmania braziliensis

UniProt:

A4HIV1_LEIBR

TriTrypDb:

LbrM.30.3680 , LBRM2903_340024600

Length:

204

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 32

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 32

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 14
NetGPI	no	yes: 0, no: 14

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Cellular components
Term	Name	Level	Count
GO:0005840	ribosome	5	13
GO:0015934	large ribosomal subunit	4	2
GO:0022625	cytosolic large ribosomal subunit	5	2
GO:0032991	protein-containing complex	1	15
GO:0043226	organelle	2	13
GO:0043228	non-membrane-bounded organelle	3	13
GO:0043229	intracellular organelle	3	13
GO:0043232	intracellular non-membrane-bounded organelle	4	13
GO:0044391	ribosomal subunit	3	2
GO:0110165	cellular anatomical entity	1	13

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Expansion

Sequence features

A4HIV1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HIV1

PDB structure(s): 6az3_M

Function

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Biological processes
Term	Name	Level	Count
GO:0002181	cytoplasmic translation	5	2
GO:0006412	translation	4	15
GO:0006518	peptide metabolic process	4	15
GO:0006807	nitrogen compound metabolic process	2	15
GO:0008152	metabolic process	1	15
GO:0009058	biosynthetic process	2	15
GO:0009059	macromolecule biosynthetic process	4	15
GO:0009987	cellular process	1	15
GO:0019538	protein metabolic process	3	15
GO:0034641	cellular nitrogen compound metabolic process	3	15

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Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	2
GO:0003723	RNA binding	4	2
GO:0003735	structural constituent of ribosome	2	15
GO:0005198	structural molecule activity	1	15
GO:0005488	binding	1	2
GO:0097159	organic cyclic compound binding	2	2
GO:1901363	heterocyclic compound binding	2	2

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_MEL_PAP_1	106	112	PF00089	0.399
CLV_NRD_NRD_1	143	145	PF00675	0.275
CLV_NRD_NRD_1	168	170	PF00675	0.274
CLV_NRD_NRD_1	193	195	PF00675	0.472
CLV_NRD_NRD_1	201	203	PF00675	0.470
CLV_NRD_NRD_1	40	42	PF00675	0.259
CLV_NRD_NRD_1	67	69	PF00675	0.259
CLV_NRD_NRD_1	70	72	PF00675	0.259
CLV_PCSK_FUR_1	38	42	PF00082	0.275
CLV_PCSK_FUR_1	65	69	PF00082	0.259

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2L2	Leptomonas seymouri	98%	100%
A0A0S4JHQ9	Bodo saltans	92%	100%
A0A1X0P6Q8	Trypanosomatidae	91%	100%
A0A3Q8IIZ6	Leishmania donovani	99%	100%
A0A3R7M146	Trypanosoma rangeli	90%	100%
A2ST55	Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z)	41%	100%
A3CW58	Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)	42%	100%
A3DMU2	Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / JCM 9404 / F1)	43%	93%
A4FZN9	Methanococcus maripaludis (strain C5 / ATCC BAA-1333)	46%	100%
A4HML1	Leishmania braziliensis	100%	100%

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