Rhodanese domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

thiosulfate sulfurtransferase, mitochondrial, putative

Species:

Leishmania braziliensis

UniProt:

A4HIT9_LEIBR

TriTrypDb:

LbrM.30.3560 , LBRM2903_300042900

Length:

247

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HIT9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HIT9

PDB structure(s): 7ane_au

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	2
GO:0004792	thiosulfate sulfurtransferase activity	5	2
GO:0016740	transferase activity	2	2
GO:0016782	transferase activity, transferring sulphur-containing groups	3	2
GO:0016783	sulfurtransferase activity	4	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	12	14	PF00675	0.463
CLV_NRD_NRD_1	151	153	PF00675	0.317
CLV_NRD_NRD_1	202	204	PF00675	0.426
CLV_PCSK_KEX2_1	12	14	PF00082	0.463
CLV_PCSK_KEX2_1	202	204	PF00082	0.426
CLV_PCSK_PC1ET2_1	202	204	PF00082	0.426
CLV_PCSK_SKI1_1	127	131	PF00082	0.362
CLV_PCSK_SKI1_1	193	197	PF00082	0.472
CLV_PCSK_SKI1_1	203	207	PF00082	0.330
CLV_PCSK_SKI1_1	5	9	PF00082	0.667
DEG_Nend_UBRbox_1	1	4	PF02207	0.663
DOC_CYCLIN_RxL_1	2	11	PF00134	0.650
DOC_MAPK_gen_1	12	20	PF00069	0.451
DOC_MAPK_gen_1	127	137	PF00069	0.489
DOC_PP4_FxxP_1	125	128	PF00568	0.476
DOC_PP4_FxxP_1	221	224	PF00568	0.467
DOC_USP7_MATH_1	191	195	PF00917	0.542
DOC_USP7_MATH_1	231	235	PF00917	0.609
DOC_WW_Pin1_4	86	91	PF00397	0.487
LIG_14-3-3_CanoR_1	232	238	PF00244	0.567
LIG_AP2alpha_2	184	186	PF02296	0.560
LIG_CSL_BTD_1	101	104	PF09270	0.517
LIG_deltaCOP1_diTrp_1	28	32	PF00928	0.378
LIG_FHA_1	1	7	PF00498	0.502
LIG_FHA_1	164	170	PF00498	0.474
LIG_FHA_1	79	85	PF00498	0.476
LIG_FHA_2	113	119	PF00498	0.501
LIG_LIR_Apic_2	121	126	PF02991	0.461
LIG_LIR_Apic_2	184	189	PF02991	0.502
LIG_LIR_Apic_2	220	224	PF02991	0.453
LIG_LIR_Apic_2	74	79	PF02991	0.558
LIG_LIR_Gen_1	117	126	PF02991	0.488
LIG_LIR_Gen_1	172	179	PF02991	0.425
LIG_LIR_Nem_3	172	177	PF02991	0.428
LIG_MYND_3	223	227	PF01753	0.481
LIG_Pex14_1	151	155	PF04695	0.476
LIG_Pex14_1	186	190	PF04695	0.427
LIG_Pex14_2	196	200	PF04695	0.421
LIG_PTB_Apo_2	113	120	PF02174	0.581
LIG_SH2_CRK	123	127	PF00017	0.470
LIG_SH2_SRC	156	159	PF00017	0.501
LIG_SH2_STAP1	110	114	PF00017	0.476
LIG_SH2_STAT3	110	113	PF00017	0.476
LIG_SH2_STAT3	216	219	PF00017	0.405
LIG_SH2_STAT3	244	247	PF00017	0.522
LIG_SH2_STAT5	41	44	PF00017	0.416
LIG_SH2_STAT5	66	69	PF00017	0.447
LIG_SUMO_SIM_anti_2	131	138	PF11976	0.476
LIG_SUMO_SIM_par_1	131	138	PF11976	0.476
LIG_SUMO_SIM_par_1	80	85	PF11976	0.497
MOD_CDC14_SPxK_1	89	92	PF00782	0.501
MOD_CDK_SPxK_1	86	92	PF00069	0.501
MOD_CK2_1	112	118	PF00069	0.467
MOD_CMANNOS	29	32	PF00535	0.384
MOD_GSK3_1	7	14	PF00069	0.564
MOD_NEK2_1	206	211	PF00069	0.393
MOD_NEK2_2	191	196	PF00069	0.539
MOD_PKA_2	11	17	PF00069	0.441
MOD_PKA_2	231	237	PF00069	0.544
MOD_Plk_4	191	197	PF00069	0.538
MOD_Plk_4	97	103	PF00069	0.499
MOD_ProDKin_1	86	92	PF00069	0.487
TRG_DiLeu_BaLyEn_6	2	7	PF01217	0.690
TRG_ENDOCYTIC_2	156	159	PF00928	0.498
TRG_ENDOCYTIC_2	174	177	PF00928	0.302
TRG_ENDOCYTIC_2	57	60	PF00928	0.516
TRG_ER_diArg_1	12	15	PF00400	0.467
TRG_NLS_MonoExtN_4	199	206	PF00514	0.418
TRG_Pf-PMV_PEXEL_1	46	50	PF00026	0.341
TRG_Pf-PMV_PEXEL_1	5	9	PF00026	0.667

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2P8	Leptomonas seymouri	90%	100%
A0A0S4JLQ7	Bodo saltans	74%	100%
A0A1X0P2T4	Trypanosomatidae	81%	100%
A0A3R7NHJ2	Trypanosoma rangeli	80%	100%
A0A3S7X422	Leishmania donovani	94%	100%
A4I644	Leishmania infantum	94%	100%
C9ZRG5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	79%	100%
E9B1C7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%
Q4Q6T5	Leishmania major	94%	100%
V5BMP6	Trypanosoma cruzi	82%	100%