Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HIR2_LEIBR

TriTrypDb:

LbrM.30.3270 , LBRM2903_300039600

Length:


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	1

A4HIR2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HIR2

PDB structure(s): 7ane_ba


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	2	4	PF00675	0.527
DEG_Nend_Nbox_1	1	3	PF02207	0.565
DOC_USP7_UBL2_3	34	38	PF12436	0.461
LIG_FHA_2	17	23	PF00498	0.401
LIG_LIR_Apic_2	49	54	PF02991	0.404
LIG_LIR_Gen_1	58	66	PF02991	0.431
LIG_LIR_Nem_3	58	63	PF02991	0.436
LIG_LIR_Nem_3	77	83	PF02991	0.526
LIG_SH2_GRB2like	12	15	PF00017	0.456
LIG_SH2_STAP1	76	80	PF00017	0.373
LIG_SH2_STAT5	43	46	PF00017	0.367
LIG_SH2_STAT5	76	79	PF00017	0.373
MOD_CK2_1	16	22	PF00069	0.405
MOD_GlcNHglycan	4	7	PF01048	0.374
MOD_GSK3_1	42	49	PF00069	0.392
MOD_NEK2_1	15	20	PF00069	0.398
MOD_NEK2_1	2	7	PF00069	0.544
MOD_NEK2_1	74	79	PF00069	0.347
MOD_PKA_2	2	8	PF00069	0.567
TRG_ENDOCYTIC_2	12	15	PF00928	0.445
TRG_ENDOCYTIC_2	47	50	PF00928	0.371
TRG_ENDOCYTIC_2	75	78	PF00928	0.432


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PB19	Leptomonas seymouri	87%	100%
A0A0S4JPT8	Bodo saltans	81%	100%
A0A3S7X3X0	Leishmania donovani	94%	100%
A0A422P0T6	Trypanosoma rangeli	84%	78%
A4I607	Leishmania infantum	94%	100%
C9ZRC9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	81%	100%
E9B198	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
Q4Q6W6	Leishmania major	93%	100%