Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HIP4_LEIBR

TriTrypDb:

LbrM.30.3090 , LBRM2903_300037600

Length:

639

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HIP4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HIP4

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	606	610	PF00656	0.473
CLV_C14_Caspase3-7	73	77	PF00656	0.553
CLV_NRD_NRD_1	2	4	PF00675	0.467
CLV_NRD_NRD_1	358	360	PF00675	0.452
CLV_NRD_NRD_1	414	416	PF00675	0.511
CLV_NRD_NRD_1	595	597	PF00675	0.400
CLV_PCSK_KEX2_1	2	4	PF00082	0.455
CLV_PCSK_KEX2_1	358	360	PF00082	0.341
CLV_PCSK_KEX2_1	414	416	PF00082	0.539
CLV_PCSK_KEX2_1	595	597	PF00082	0.400

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6D3	Leptomonas seymouri	66%	100%
A0A1X0P1N4	Trypanosomatidae	42%	100%
A0A3S7X3S8	Leishmania donovani	85%	92%
A0A422P0R1	Trypanosoma rangeli	39%	100%
A4I5Z1	Leishmania infantum	85%	100%
C9ZRB4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	100%
E9B184	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%
Q4Q6Y0	Leishmania major	84%	100%
V5BSF5	Trypanosoma cruzi	38%	100%

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