Chalcone_isomerase domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HIM7_LEIBR

TriTrypDb:

LbrM.30.2910 , LBRM2903_300035800

Length:

191


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	5
GO:0110165	cellular anatomical entity	1	5

A4HIM7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HIM7


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	128	132	PF00656	0.439
CLV_PCSK_SKI1_1	101	105	PF00082	0.674
CLV_PCSK_SKI1_1	143	147	PF00082	0.651
CLV_PCSK_SKI1_1	87	91	PF00082	0.633
DEG_APCC_DBOX_1	9	17	PF00400	0.415
DEG_Nend_Nbox_1	1	3	PF02207	0.534
DOC_PP1_RVXF_1	141	148	PF00149	0.375
DOC_PP4_FxxP_1	177	180	PF00568	0.385
DOC_USP7_MATH_1	103	107	PF00917	0.487
DOC_WW_Pin1_4	95	100	PF00397	0.465
LIG_14-3-3_CanoR_1	10	14	PF00244	0.449
LIG_14-3-3_CanoR_1	143	148	PF00244	0.394
LIG_EH1_1	106	114	PF00400	0.308
LIG_LIR_Gen_1	171	182	PF02991	0.323
LIG_LIR_Nem_3	146	150	PF02991	0.396
LIG_LIR_Nem_3	159	165	PF02991	0.339
LIG_LIR_Nem_3	171	177	PF02991	0.303
LIG_MYND_1	137	141	PF01753	0.430
LIG_Pex14_2	183	187	PF04695	0.436
LIG_PTB_Apo_2	27	34	PF02174	0.398
LIG_SH2_STAT5	27	30	PF00017	0.553
LIG_WRC_WIRS_1	104	109	PF05994	0.461
MOD_CDK_SPxK_1	95	101	PF00069	0.466
MOD_CK1_1	4	10	PF00069	0.562
MOD_GlcNHglycan	18	21	PF01048	0.427
MOD_GlcNHglycan	23	26	PF01048	0.430
MOD_GlcNHglycan	3	6	PF01048	0.463
MOD_GlcNHglycan	51	54	PF01048	0.669
MOD_NEK2_1	1	6	PF00069	0.537
MOD_NEK2_1	129	134	PF00069	0.476
MOD_PIKK_1	64	70	PF00454	0.459
MOD_PKA_2	9	15	PF00069	0.364
MOD_Plk_1	56	62	PF00069	0.463
MOD_Plk_4	113	119	PF00069	0.344
MOD_Plk_4	143	149	PF00069	0.345
MOD_Plk_4	4	10	PF00069	0.550
MOD_Plk_4	78	84	PF00069	0.434
MOD_ProDKin_1	95	101	PF00069	0.466
MOD_SUMO_for_1	118	121	PF00179	0.440
TRG_NES_CRM1_1	64	75	PF08389	0.384
TRG_Pf-PMV_PEXEL_1	110	114	PF00026	0.608


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCB6	Leptomonas seymouri	63%	100%
A0A0S4ITI4	Bodo saltans	33%	83%
A0A1X0P1H2	Trypanosomatidae	39%	97%
A0A3Q8IJN4	Leishmania donovani	83%	100%
A0A3R7M429	Trypanosoma rangeli	40%	100%
A4I5X2	Leishmania infantum	83%	100%
C9ZR96	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
E9B166	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%
Q4Q6Z9	Leishmania major	82%	100%