LeishMANIAdb
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Gp_dh_N domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Gp_dh_N domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HIK9_LEIBR
TriTrypDb:
LbrM.30.2730 , LBRM2903_300033800 *
Length:
88

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 5
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HIK9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HIK9

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 29 31 PF00675 0.443
CLV_PCSK_KEX2_1 28 30 PF00082 0.457
CLV_PCSK_PC1ET2_1 28 30 PF00082 0.457
DOC_MAPK_RevD_3 17 30 PF00069 0.438
DOC_PP2B_LxvP_1 55 58 PF13499 0.536
DOC_WW_Pin1_4 61 66 PF00397 0.552
LIG_14-3-3_CanoR_1 29 33 PF00244 0.454
LIG_Actin_WH2_2 36 51 PF00022 0.412
LIG_Actin_WH2_2 67 83 PF00022 0.579
LIG_BRCT_BRCA1_1 78 82 PF00533 0.445
LIG_LIR_Gen_1 3 12 PF02991 0.679
LIG_SH2_GRB2like 4 7 PF00017 0.546
LIG_SH2_STAP1 4 8 PF00017 0.646
LIG_SH3_3 59 65 PF00018 0.543
LIG_SH3_5 65 69 PF00018 0.536
MOD_CK1_1 51 57 PF00069 0.497
MOD_GSK3_1 76 83 PF00069 0.452
MOD_N-GLC_1 8 13 PF02516 0.618
MOD_NEK2_1 2 7 PF00069 0.491
MOD_NEK2_1 48 53 PF00069 0.599
MOD_NEK2_1 80 85 PF00069 0.442
MOD_PIKK_1 10 16 PF00454 0.430
MOD_PIKK_1 48 54 PF00454 0.446
MOD_PKA_1 28 34 PF00069 0.433
MOD_PKA_2 28 34 PF00069 0.433
MOD_Plk_1 76 82 PF00069 0.437
MOD_Plk_1 8 14 PF00069 0.518
MOD_ProDKin_1 61 67 PF00069 0.546
MOD_SUMO_rev_2 64 71 PF00179 0.444
TRG_ENDOCYTIC_2 4 7 PF00928 0.642

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IJF7 Leptomonas seymouri 33% 81%
A0A3Q8IEZ6 Leishmania donovani 59% 81%
A4I5V4 Leishmania infantum 59% 81%
E9B149 Leishmania mexicana (strain MHOM/GT/2001/U1103) 64% 81%
Q4Q717 Leishmania major 58% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS