LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

SH3 domain protein-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
SH3 domain protein-like protein
Gene product:
SH3 domain protein-like protein
Species:
Leishmania braziliensis
UniProt:
A4HIK1_LEIBR
TriTrypDb:
LbrM.30.2650 , LBRM2903_300033000
Length:
294

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HIK1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HIK1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 282 286 PF00656 0.450
CLV_NRD_NRD_1 189 191 PF00675 0.486
CLV_NRD_NRD_1 219 221 PF00675 0.410
CLV_NRD_NRD_1 48 50 PF00675 0.297
CLV_PCSK_KEX2_1 189 191 PF00082 0.505
CLV_PCSK_KEX2_1 47 49 PF00082 0.297
CLV_PCSK_SKI1_1 163 167 PF00082 0.592
CLV_PCSK_SKI1_1 281 285 PF00082 0.667
DEG_Nend_UBRbox_1 1 4 PF02207 0.370
DEG_SCF_FBW7_1 86 93 PF00400 0.489
DEG_SPOP_SBC_1 104 108 PF00917 0.567
DEG_SPOP_SBC_1 144 148 PF00917 0.740
DOC_CKS1_1 87 92 PF01111 0.654
DOC_CYCLIN_RxL_1 160 167 PF00134 0.647
DOC_MAPK_MEF2A_6 11 20 PF00069 0.239
DOC_PP2B_LxvP_1 257 260 PF13499 0.592
DOC_PP4_MxPP_1 69 72 PF00568 0.393
DOC_USP7_MATH_1 122 126 PF00917 0.576
DOC_USP7_MATH_1 142 146 PF00917 0.693
DOC_USP7_MATH_1 154 158 PF00917 0.614
DOC_USP7_MATH_1 245 249 PF00917 0.539
DOC_USP7_MATH_1 260 264 PF00917 0.702
DOC_USP7_MATH_1 65 69 PF00917 0.640
DOC_USP7_MATH_1 72 76 PF00917 0.712
DOC_USP7_MATH_1 80 84 PF00917 0.648
DOC_WW_Pin1_4 123 128 PF00397 0.691
DOC_WW_Pin1_4 131 136 PF00397 0.637
DOC_WW_Pin1_4 149 154 PF00397 0.634
DOC_WW_Pin1_4 263 268 PF00397 0.660
DOC_WW_Pin1_4 82 87 PF00397 0.673
LIG_14-3-3_CanoR_1 189 197 PF00244 0.466
LIG_14-3-3_CanoR_1 278 284 PF00244 0.457
LIG_BRCT_BRCA1_1 108 112 PF00533 0.505
LIG_EVH1_2 77 81 PF00568 0.468
LIG_FHA_1 263 269 PF00498 0.602
LIG_FHA_1 27 33 PF00498 0.410
LIG_FHA_2 108 114 PF00498 0.635
LIG_FHA_2 91 97 PF00498 0.503
LIG_LIR_Gen_1 180 191 PF02991 0.593
LIG_LIR_Gen_1 35 43 PF02991 0.279
LIG_LIR_Nem_3 180 186 PF02991 0.449
LIG_LIR_Nem_3 35 40 PF02991 0.286
LIG_MYND_1 127 131 PF01753 0.642
LIG_PCNA_yPIPBox_3 163 177 PF02747 0.527
LIG_PTB_Apo_2 176 183 PF02174 0.530
LIG_PTB_Phospho_1 176 182 PF10480 0.531
LIG_SH2_GRB2like 182 185 PF00017 0.464
LIG_SH2_STAP1 253 257 PF00017 0.524
LIG_SH2_STAT3 182 185 PF00017 0.464
LIG_SH2_STAT3 253 256 PF00017 0.429
LIG_SH2_STAT5 182 185 PF00017 0.528
LIG_SH2_STAT5 3 6 PF00017 0.359
LIG_SH2_STAT5 56 59 PF00017 0.357
LIG_SH3_3 129 135 PF00018 0.490
LIG_SH3_3 265 271 PF00018 0.648
LIG_SUMO_SIM_anti_2 17 22 PF11976 0.197
MOD_CDC14_SPxK_1 266 269 PF00782 0.463
MOD_CDC14_SPxK_1 85 88 PF00782 0.638
MOD_CDK_SPxK_1 263 269 PF00069 0.666
MOD_CDK_SPxK_1 82 88 PF00069 0.643
MOD_CK1_1 125 131 PF00069 0.631
MOD_CK1_1 145 151 PF00069 0.580
MOD_CK1_1 262 268 PF00069 0.639
MOD_CK1_1 270 276 PF00069 0.670
MOD_CK2_1 196 202 PF00069 0.420
MOD_CK2_1 24 30 PF00069 0.489
MOD_CK2_1 58 64 PF00069 0.472
MOD_CK2_1 90 96 PF00069 0.500
MOD_GlcNHglycan 156 159 PF01048 0.440
MOD_GlcNHglycan 191 194 PF01048 0.529
MOD_GlcNHglycan 198 201 PF01048 0.511
MOD_GlcNHglycan 213 217 PF01048 0.555
MOD_GlcNHglycan 26 29 PF01048 0.197
MOD_GlcNHglycan 262 265 PF01048 0.600
MOD_GlcNHglycan 272 275 PF01048 0.683
MOD_GlcNHglycan 59 63 PF01048 0.523
MOD_GlcNHglycan 74 77 PF01048 0.585
MOD_GlcNHglycan 96 100 PF01048 0.639
MOD_GSK3_1 103 110 PF00069 0.597
MOD_GSK3_1 145 152 PF00069 0.654
MOD_GSK3_1 247 254 PF00069 0.496
MOD_GSK3_1 259 266 PF00069 0.575
MOD_GSK3_1 82 89 PF00069 0.574
MOD_GSK3_1 90 97 PF00069 0.535
MOD_N-GLC_1 104 109 PF02516 0.718
MOD_N-GLC_1 115 120 PF02516 0.628
MOD_NEK2_1 103 108 PF00069 0.756
MOD_NEK2_1 279 284 PF00069 0.551
MOD_NEK2_1 81 86 PF00069 0.692
MOD_PIKK_1 252 258 PF00454 0.425
MOD_PKA_1 189 195 PF00069 0.536
MOD_PKA_2 189 195 PF00069 0.454
MOD_PKA_2 94 100 PF00069 0.503
MOD_Plk_1 115 121 PF00069 0.614
MOD_Plk_1 16 22 PF00069 0.304
MOD_Plk_1 212 218 PF00069 0.442
MOD_Plk_4 16 22 PF00069 0.444
MOD_Plk_4 52 58 PF00069 0.378
MOD_ProDKin_1 123 129 PF00069 0.692
MOD_ProDKin_1 131 137 PF00069 0.634
MOD_ProDKin_1 149 155 PF00069 0.632
MOD_ProDKin_1 263 269 PF00069 0.666
MOD_ProDKin_1 82 88 PF00069 0.677
MOD_SUMO_for_1 177 180 PF00179 0.403
MOD_SUMO_for_1 21 24 PF00179 0.355
MOD_SUMO_for_1 38 41 PF00179 0.150
MOD_SUMO_rev_2 238 245 PF00179 0.441
TRG_AP2beta_CARGO_1 180 190 PF09066 0.414
TRG_DiLeu_BaEn_4 13 19 PF01217 0.410
TRG_ENDOCYTIC_2 3 6 PF00928 0.357
TRG_ER_diArg_1 233 236 PF00400 0.440
TRG_ER_diArg_1 47 49 PF00400 0.360
TRG_Pf-PMV_PEXEL_1 163 167 PF00026 0.609
TRG_Pf-PMV_PEXEL_1 220 224 PF00026 0.426

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I2T5 Leptomonas seymouri 59% 92%
A0A1X0P1K4 Trypanosomatidae 41% 100%
A0A3Q8IG02 Leishmania donovani 80% 100%
A0A422NLQ1 Trypanosoma rangeli 39% 100%
A4I5U6 Leishmania infantum 80% 100%
C9ZR67 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
E9B141 Leishmania mexicana (strain MHOM/GT/2001/U1103) 82% 100%
Q4Q725 Leishmania major 80% 100%
V5BX71 Trypanosoma cruzi 44% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2026 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS