LeishMANIAdb
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Formate--tetrahydrofolate ligase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Formate--tetrahydrofolate ligase
Gene product:
formate--tetrahydrofolate ligase
Species:
Leishmania braziliensis
UniProt:
A4HIJ1_LEIBR
TriTrypDb:
LbrM.30.2550 , LBRM2903_300032000 *
Length:
622

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 5
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 16
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Cellular components
Term Name Level Count
GO:0005829 cytosol 2 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

A4HIJ1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HIJ1

Function

Biological processes
Term Name Level Count
GO:0006575 cellular modified amino acid metabolic process 3 9
GO:0006725 cellular aromatic compound metabolic process 3 9
GO:0006730 one-carbon metabolic process 3 9
GO:0006760 folic acid-containing compound metabolic process 4 9
GO:0006807 nitrogen compound metabolic process 2 9
GO:0008152 metabolic process 1 9
GO:0009987 cellular process 1 9
GO:0035999 tetrahydrofolate interconversion 4 9
GO:0042558 pteridine-containing compound metabolic process 4 9
GO:0044237 cellular metabolic process 2 9
GO:0044281 small molecule metabolic process 2 9
GO:0046483 heterocycle metabolic process 3 9
GO:0046653 tetrahydrofolate metabolic process 5 9
GO:0071704 organic substance metabolic process 2 9
GO:1901360 organic cyclic compound metabolic process 3 9
GO:1901564 organonitrogen compound metabolic process 3 9
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 9
GO:0003824 catalytic activity 1 9
GO:0004329 formate-tetrahydrofolate ligase activity 4 9
GO:0005488 binding 1 9
GO:0005524 ATP binding 5 9
GO:0016874 ligase activity 2 9
GO:0016879 ligase activity, forming carbon-nitrogen bonds 3 9
GO:0017076 purine nucleotide binding 4 9
GO:0030554 adenyl nucleotide binding 5 9
GO:0032553 ribonucleotide binding 3 9
GO:0032555 purine ribonucleotide binding 4 9
GO:0032559 adenyl ribonucleotide binding 5 9
GO:0035639 purine ribonucleoside triphosphate binding 4 9
GO:0036094 small molecule binding 2 9
GO:0043167 ion binding 2 9
GO:0043168 anion binding 3 9
GO:0097159 organic cyclic compound binding 2 9
GO:0097367 carbohydrate derivative binding 2 9
GO:1901265 nucleoside phosphate binding 3 9
GO:1901363 heterocyclic compound binding 2 9
GO:0016491 oxidoreductase activity 2 2
GO:0016787 hydrolase activity 2 3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 173 175 PF00675 0.223
CLV_NRD_NRD_1 224 226 PF00675 0.261
CLV_NRD_NRD_1 250 252 PF00675 0.250
CLV_NRD_NRD_1 3 5 PF00675 0.467
CLV_NRD_NRD_1 430 432 PF00675 0.248
CLV_NRD_NRD_1 57 59 PF00675 0.165
CLV_PCSK_KEX2_1 173 175 PF00082 0.223
CLV_PCSK_KEX2_1 188 190 PF00082 0.223
CLV_PCSK_KEX2_1 224 226 PF00082 0.236
CLV_PCSK_KEX2_1 250 252 PF00082 0.290
CLV_PCSK_KEX2_1 57 59 PF00082 0.223
CLV_PCSK_PC1ET2_1 188 190 PF00082 0.248
CLV_PCSK_SKI1_1 173 177 PF00082 0.243
CLV_PCSK_SKI1_1 201 205 PF00082 0.216
CLV_PCSK_SKI1_1 224 228 PF00082 0.235
CLV_PCSK_SKI1_1 246 250 PF00082 0.210
CLV_PCSK_SKI1_1 346 350 PF00082 0.290
CLV_PCSK_SKI1_1 395 399 PF00082 0.223
CLV_PCSK_SKI1_1 585 589 PF00082 0.223
DEG_APCC_DBOX_1 275 283 PF00400 0.490
DEG_SCF_FBW7_2 73 80 PF00400 0.423
DOC_MAPK_FxFP_2 586 589 PF00069 0.423
DOC_MAPK_gen_1 188 195 PF00069 0.425
DOC_MAPK_gen_1 232 241 PF00069 0.414
DOC_MAPK_gen_1 250 258 PF00069 0.470
DOC_MAPK_gen_1 276 284 PF00069 0.424
DOC_MAPK_gen_1 431 439 PF00069 0.448
DOC_MAPK_gen_1 48 55 PF00069 0.448
DOC_MAPK_HePTP_8 229 241 PF00069 0.490
DOC_MAPK_MEF2A_6 232 241 PF00069 0.490
DOC_MAPK_MEF2A_6 431 439 PF00069 0.424
DOC_MAPK_MEF2A_6 48 55 PF00069 0.448
DOC_MAPK_RevD_3 212 225 PF00069 0.423
DOC_PP1_RVXF_1 206 212 PF00149 0.448
DOC_PP1_RVXF_1 393 400 PF00149 0.427
DOC_PP4_FxxP_1 433 436 PF00568 0.423
DOC_PP4_FxxP_1 571 574 PF00568 0.423
DOC_PP4_FxxP_1 586 589 PF00568 0.423
DOC_USP7_MATH_1 244 248 PF00917 0.374
DOC_USP7_MATH_1 43 47 PF00917 0.418
DOC_USP7_UBL2_3 188 192 PF12436 0.433
DOC_USP7_UBL2_3 197 201 PF12436 0.410
DOC_WW_Pin1_4 180 185 PF00397 0.448
DOC_WW_Pin1_4 320 325 PF00397 0.423
DOC_WW_Pin1_4 492 497 PF00397 0.469
DOC_WW_Pin1_4 59 64 PF00397 0.374
DOC_WW_Pin1_4 73 78 PF00397 0.424
LIG_14-3-3_CanoR_1 173 182 PF00244 0.445
LIG_14-3-3_CanoR_1 208 212 PF00244 0.503
LIG_14-3-3_CanoR_1 224 233 PF00244 0.457
LIG_Actin_WH2_2 222 237 PF00022 0.423
LIG_BIR_II_1 1 5 PF00653 0.369
LIG_BIR_III_2 23 27 PF00653 0.478
LIG_FHA_1 1 7 PF00498 0.430
LIG_FHA_1 111 117 PF00498 0.423
LIG_FHA_1 137 143 PF00498 0.423
LIG_FHA_1 174 180 PF00498 0.448
LIG_FHA_1 321 327 PF00498 0.444
LIG_FHA_1 378 384 PF00498 0.468
LIG_FHA_1 570 576 PF00498 0.458
LIG_FHA_1 613 619 PF00498 0.422
LIG_FHA_1 82 88 PF00498 0.423
LIG_FHA_2 163 169 PF00498 0.423
LIG_FHA_2 202 208 PF00498 0.437
LIG_FHA_2 250 256 PF00498 0.448
LIG_FHA_2 292 298 PF00498 0.437
LIG_FHA_2 446 452 PF00498 0.419
LIG_FXI_DFP_1 544 548 PF00024 0.278
LIG_GBD_Chelix_1 343 351 PF00786 0.223
LIG_GBD_Chelix_1 89 97 PF00786 0.223
LIG_IBAR_NPY_1 42 44 PF08397 0.404
LIG_LIR_Apic_2 569 574 PF02991 0.423
LIG_LIR_Apic_2 7 13 PF02991 0.276
LIG_LIR_Gen_1 210 218 PF02991 0.407
LIG_LIR_Gen_1 497 507 PF02991 0.490
LIG_LIR_Gen_1 538 547 PF02991 0.490
LIG_LIR_Nem_3 181 185 PF02991 0.503
LIG_LIR_Nem_3 210 214 PF02991 0.461
LIG_LIR_Nem_3 220 226 PF02991 0.445
LIG_LIR_Nem_3 371 376 PF02991 0.423
LIG_LIR_Nem_3 497 502 PF02991 0.425
LIG_REV1ctd_RIR_1 371 381 PF16727 0.423
LIG_SH2_CRK 125 129 PF00017 0.423
LIG_SH2_CRK 172 176 PF00017 0.448
LIG_SH2_GRB2like 528 531 PF00017 0.423
LIG_SH2_GRB2like 606 609 PF00017 0.490
LIG_SH2_PTP2 67 70 PF00017 0.423
LIG_SH2_STAP1 125 129 PF00017 0.423
LIG_SH2_STAT5 528 531 PF00017 0.436
LIG_SH2_STAT5 67 70 PF00017 0.423
LIG_SH3_2 598 603 PF14604 0.423
LIG_SH3_3 595 601 PF00018 0.423
LIG_SUMO_SIM_anti_2 451 457 PF11976 0.445
LIG_SUMO_SIM_par_1 264 271 PF11976 0.490
LIG_TRAF2_1 204 207 PF00917 0.416
LIG_TRAF2_1 408 411 PF00917 0.404
LIG_TRAF2_1 459 462 PF00917 0.490
LIG_UBA3_1 423 432 PF00899 0.427
MOD_CDK_SPxxK_3 59 66 PF00069 0.427
MOD_CK1_1 257 263 PF00069 0.403
MOD_CK1_1 445 451 PF00069 0.514
MOD_CK1_1 83 89 PF00069 0.423
MOD_CK2_1 201 207 PF00069 0.420
MOD_CK2_1 445 451 PF00069 0.419
MOD_CK2_1 505 511 PF00069 0.490
MOD_GlcNHglycan 32 35 PF01048 0.240
MOD_GlcNHglycan 380 383 PF01048 0.237
MOD_GlcNHglycan 505 508 PF01048 0.165
MOD_GSK3_1 106 113 PF00069 0.423
MOD_GSK3_1 312 319 PF00069 0.439
MOD_GSK3_1 32 39 PF00069 0.497
MOD_N-GLC_1 338 343 PF02516 0.223
MOD_N-GLC_1 529 534 PF02516 0.190
MOD_NEK2_1 254 259 PF00069 0.430
MOD_NEK2_1 390 395 PF00069 0.496
MOD_NEK2_1 551 556 PF00069 0.423
MOD_PIKK_1 106 112 PF00454 0.423
MOD_PIKK_1 123 129 PF00454 0.423
MOD_PIKK_1 162 168 PF00454 0.423
MOD_PIKK_1 201 207 PF00454 0.365
MOD_PIKK_1 551 557 PF00454 0.423
MOD_PKA_1 173 179 PF00069 0.423
MOD_PKA_1 224 230 PF00069 0.448
MOD_PKA_2 173 179 PF00069 0.423
MOD_PKA_2 207 213 PF00069 0.509
MOD_PKA_2 224 230 PF00069 0.434
MOD_PKA_2 249 255 PF00069 0.448
MOD_PKA_2 378 384 PF00069 0.423
MOD_Plk_1 244 250 PF00069 0.434
MOD_Plk_1 254 260 PF00069 0.448
MOD_Plk_1 338 344 PF00069 0.427
MOD_Plk_1 592 598 PF00069 0.423
MOD_Plk_4 312 318 PF00069 0.435
MOD_Plk_4 32 38 PF00069 0.538
MOD_Plk_4 338 344 PF00069 0.423
MOD_Plk_4 51 57 PF00069 0.432
MOD_ProDKin_1 180 186 PF00069 0.448
MOD_ProDKin_1 320 326 PF00069 0.423
MOD_ProDKin_1 492 498 PF00069 0.469
MOD_ProDKin_1 59 65 PF00069 0.374
MOD_ProDKin_1 73 79 PF00069 0.424
MOD_SUMO_rev_2 527 537 PF00179 0.517
TRG_DiLeu_BaLyEn_6 586 591 PF01217 0.490
TRG_ENDOCYTIC_2 125 128 PF00928 0.423
TRG_ENDOCYTIC_2 172 175 PF00928 0.448
TRG_ENDOCYTIC_2 544 547 PF00928 0.448
TRG_ENDOCYTIC_2 606 609 PF00928 0.490
TRG_ENDOCYTIC_2 67 70 PF00928 0.423
TRG_ER_diArg_1 172 174 PF00400 0.423
TRG_ER_diArg_1 223 225 PF00400 0.517
TRG_ER_diArg_1 275 278 PF00400 0.448
TRG_ER_diArg_1 56 58 PF00400 0.365
TRG_NES_CRM1_1 451 462 PF08389 0.374
TRG_Pf-PMV_PEXEL_1 173 178 PF00026 0.223
TRG_Pf-PMV_PEXEL_1 232 236 PF00026 0.223

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1HXI3 Leptomonas seymouri 86% 100%
A0A1X0P286 Trypanosomatidae 76% 100%
A0A3Q8IEE5 Leishmania donovani 91% 100%
A0AJY2 Listeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / CIP 8149 / NCTC 11857 / SLCC 5334 / V8) 43% 100%
A0JZ10 Arthrobacter sp. (strain FB24) 46% 100%
A0KIN9 Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049) 48% 100%
A0KSN0 Shewanella sp. (strain ANA-3) 47% 100%
A0LLR3 Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) 41% 100%
A0PXN0 Clostridium novyi (strain NT) 46% 100%
A0RD97 Bacillus thuringiensis (strain Al Hakam) 44% 100%
A1B1M8 Paracoccus denitrificans (strain Pd 1222) 47% 100%
A1JMA3 Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081) 46% 100%
A1KS57 Neisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 / DSM 15464 / FAM18) 47% 100%
A1R8N9 Paenarthrobacter aurescens (strain TC1) 43% 100%
A1RFN3 Shewanella sp. (strain W3-18-1) 46% 100%
A1SAE2 Shewanella amazonensis (strain ATCC BAA-1098 / SB2B) 45% 100%
A1SQH3 Nocardioides sp. (strain ATCC BAA-499 / JS614) 48% 100%
A2REC4 Streptococcus pyogenes serotype M5 (strain Manfredo) 44% 100%
A2RGS2 Streptococcus pyogenes serotype M5 (strain Manfredo) 44% 100%
A2RLK1 Lactococcus lactis subsp. cremoris (strain MG1363) 45% 100%
A2SKX8 Methylibium petroleiphilum (strain ATCC BAA-1232 / LMG 22953 / PM1) 46% 100%
A2SS72 Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z) 46% 100%
A3CL27 Streptococcus sanguinis (strain SK36) 44% 100%
A3CN49 Streptococcus sanguinis (strain SK36) 43% 100%
A3CZY6 Shewanella baltica (strain OS155 / ATCC BAA-1091) 47% 100%
A3DI22 Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) 48% 100%
A3MZI4 Actinobacillus pleuropneumoniae serotype 5b (strain L20) 46% 100%
A3PM52 Cereibacter sphaeroides (strain ATCC 17029 / ATH 2.4.9) 49% 100%
A3QA17 Shewanella loihica (strain ATCC BAA-1088 / PV-4) 49% 100%
A4FL80 Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338) 50% 100%
A4I5T5 Leishmania infantum 91% 100%
A4J0S6 Desulforamulus reducens (strain ATCC BAA-1160 / DSM 100696 / MI-1) 48% 100%
A4SPE5 Aeromonas salmonicida (strain A449) 48% 100%
A4VU67 Streptococcus suis (strain 05ZYH33) 43% 100%
A4W0G0 Streptococcus suis (strain 98HAH33) 43% 100%
A4WQ11 Cereibacter sphaeroides (strain ATCC 17025 / ATH 2.4.3) 48% 100%
A4XIU2 Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903 / Tp8T 6331) 42% 100%
A4YAP3 Shewanella putrefaciens (strain CN-32 / ATCC BAA-453) 46% 100%
A5G276 Acidiphilium cryptum (strain JF-5) 48% 100%
A5I7P9 Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A) 46% 100%
A5ILJ8 Thermotoga petrophila (strain ATCC BAA-488 / DSM 13995 / JCM 10881 / RKU-1) 43% 100%
A5ITQ4 Staphylococcus aureus (strain JH9) 43% 100%
A5N5B3 Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680) 44% 100%
A5UPV2 Roseiflexus sp. (strain RS-1) 50% 100%
A5VHS9 Limosilactobacillus reuteri (strain DSM 20016) 42% 100%
A5WI04 Psychrobacter sp. (strain PRwf-1) 44% 100%
A6L4P0 Phocaeicola vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / CCUG 4940 / NBRC 14291 / NCTC 11154) 40% 100%
A6LAR6 Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152) 40% 100%
A6LJS5 Thermosipho melanesiensis (strain DSM 12029 / CIP 104789 / BI429) 42% 100%
A6LPL1 Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) 44% 100%
A6QHR5 Staphylococcus aureus (strain Newman) 43% 100%
A6U2J8 Staphylococcus aureus (strain JH1) 43% 100%
A6UBV0 Sinorhizobium medicae (strain WSM419) 48% 100%
A6WSY9 Shewanella baltica (strain OS185) 46% 100%
A7FZB0 Clostridium botulinum (strain ATCC 19397 / Type A) 46% 100%
A7GJB8 Clostridium botulinum (strain Langeland / NCTC 10281 / Type F) 46% 100%
A7GZZ0 Campylobacter curvus (strain 525.92) 41% 100%
A7HLZ4 Fervidobacterium nodosum (strain ATCC 35602 / DSM 5306 / Rt17-B1) 44% 100%
A7N5E9 Vibrio campbellii (strain ATCC BAA-1116) 47% 100%
A7NGQ9 Roseiflexus castenholzii (strain DSM 13941 / HLO8) 50% 100%
A7X3G5 Staphylococcus aureus (strain Mu3 / ATCC 700698) 43% 100%
A8F7D5 Pseudothermotoga lettingae (strain ATCC BAA-301 / DSM 14385 / NBRC 107922 / TMO) 43% 100%
A8FEC9 Bacillus pumilus (strain SAFR-032) 44% 100%
A8FQV1 Shewanella sediminis (strain HAW-EB3) 48% 100%
A8H8Z4 Shewanella pealeana (strain ATCC 700345 / ANG-SQ1) 47% 100%
A8LIR1 Dinoroseobacter shibae (strain DSM 16493 / NCIMB 14021 / DFL 12) 46% 100%
A8MIN1 Alkaliphilus oremlandii (strain OhILAs) 46% 100%
A8Z2Q0 Staphylococcus aureus (strain USA300 / TCH1516) 43% 100%
A8Z6G1 Campylobacter concisus (strain 13826) 43% 100%
A8ZZJ0 Desulfococcus oleovorans (strain DSM 6200 / JCM 39069 / Hxd3) 43% 100%
A9B4H8 Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95) 46% 100%
A9BIV8 Petrotoga mobilis (strain DSM 10674 / SJ95) 42% 100%
A9IM41 Bartonella tribocorum (strain CIP 105476 / IBS 506) 46% 100%
A9KNJ5 Lachnoclostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg) 48% 100%
A9L3Z6 Shewanella baltica (strain OS195) 47% 100%
A9M1J1 Neisseria meningitidis serogroup C (strain 053442) 46% 100%
A9NE95 Acholeplasma laidlawii (strain PG-8A) 38% 100%
A9VZT0 Methylorubrum extorquens (strain PA1) 46% 100%
A9WIW3 Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) 46% 100%
A9WMW3 Renibacterium salmoninarum (strain ATCC 33209 / DSM 20767 / JCM 11484 / NBRC 15589 / NCIMB 2235) 42% 100%
B0K5A5 Thermoanaerobacter sp. (strain X514) 47% 100%
B0KC36 Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) 47% 100%
B0S0G1 Finegoldia magna (strain ATCC 29328 / DSM 20472 / WAL 2508) 43% 100%
B0TBP1 Heliobacterium modesticaldum (strain ATCC 51547 / Ice1) 48% 100%
B0TVP3 Shewanella halifaxensis (strain HAW-EB4) 47% 100%
B0UQF5 Methylobacterium sp. (strain 4-46) 47% 100%
B1IC26 Streptococcus pneumoniae (strain Hungary19A-6) 44% 100%
B1IGY1 Clostridium botulinum (strain Okra / Type B1) 46% 100%
B1KJC0 Shewanella woodyi (strain ATCC 51908 / MS32) 49% 100%
B1KTC6 Clostridium botulinum (strain Loch Maree / Type A3) 45% 100%
B1LAQ7 Thermotoga sp. (strain RQ2) 43% 100%
B1M0D1 Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831 / NBRC 15690 / NCIMB 10815 / 0-1) 46% 100%
B1MY45 Leuconostoc citreum (strain KM20) 44% 100%
B1ZJ88 Methylorubrum populi (strain ATCC BAA-705 / NCIMB 13946 / BJ001) 47% 100%
B2A3Q6 Natranaerobius thermophilus (strain ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF) 46% 100%
B2G5A9 Limosilactobacillus reuteri (strain JCM 1112) 42% 100%
B2GF64 Limosilactobacillus fermentum (strain NBRC 3956 / LMG 18251) 44% 100%
B2IC30 Beijerinckia indica subsp. indica (strain ATCC 9039 / DSM 1715 / NCIMB 8712) 46% 100%
B2IPQ3 Streptococcus pneumoniae (strain CGSP14) 44% 100%
B2KDK9 Elusimicrobium minutum (strain Pei191) 46% 100%
B2TI29 Clostridium botulinum (strain Eklund 17B / Type B) 44% 100%
B2UXU5 Clostridium botulinum (strain Alaska E43 / Type E3) 44% 100%
B3GX43 Actinobacillus pleuropneumoniae serotype 7 (strain AP76) 46% 100%
B3PV59 Rhizobium etli (strain CIAT 652) 46% 100%
B3WEG3 Lacticaseibacillus casei (strain BL23) 43% 100%
B4ET09 Proteus mirabilis (strain HI4320) 47% 100%
B4RP08 Neisseria gonorrhoeae (strain NCCP11945) 46% 100%
B4U2T6 Streptococcus equi subsp. zooepidemicus (strain MGCS10565) 44% 100%
B5E4W4 Streptococcus pneumoniae serotype 19F (strain G54) 45% 100%
B5FG96 Aliivibrio fischeri (strain MJ11) 47% 100%
B5YJE1 Thermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87) 44% 100%
B5ZYA2 Rhizobium leguminosarum bv. trifolii (strain WSM2304) 47% 100%
B6EIJ9 Aliivibrio salmonicida (strain LFI1238) 44% 100%
B7HP29 Bacillus cereus (strain AH187) 44% 100%
B7IG29 Thermosipho africanus (strain TCF52B) 44% 100%
B7IUA4 Bacillus cereus (strain G9842) 45% 100%
B7JLG8 Bacillus cereus (strain AH820) 44% 100%
B7L0A5 Methylorubrum extorquens (strain CM4 / NCIMB 13688) 46% 100%
B7VSJ2 Vibrio atlanticus (strain LGP32) 47% 100%
B8CI99 Shewanella piezotolerans (strain WP3 / JCM 13877) 47% 100%
B8D067 Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562) 46% 100%
B8DDM6 Listeria monocytogenes serotype 4a (strain HCC23) 43% 100%
B8ECE1 Shewanella baltica (strain OS223) 47% 100%
B8EKB9 Methylocella silvestris (strain DSM 15510 / CIP 108128 / LMG 27833 / NCIMB 13906 / BL2) 47% 100%
B8FGU7 Desulfatibacillum aliphaticivorans 41% 100%
B8GC03 Chloroflexus aggregans (strain MD-66 / DSM 9485) 47% 100%
B8I3S9 Ruminiclostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10) 46% 100%
B8IBS4 Methylobacterium nodulans (strain LMG 21967 / CNCM I-2342 / ORS 2060) 47% 100%
B8J0C2 Desulfovibrio desulfuricans (strain ATCC 27774 / DSM 6949 / MB) 45% 100%
B8ZJQ0 Streptococcus pneumoniae (strain ATCC 700669 / Spain 23F-1) 44% 100%
B9DN77 Staphylococcus carnosus (strain TM300) 43% 100%
B9DS83 Streptococcus uberis (strain ATCC BAA-854 / 0140J) 44% 100%
B9DYW1 Clostridium kluyveri (strain NBRC 12016) 44% 100%
B9IYP4 Bacillus cereus (strain Q1) 44% 100%
B9J7E8 Agrobacterium radiobacter (strain K84 / ATCC BAA-868) 48% 100%
B9JZN5 Agrobacterium vitis (strain S4 / ATCC BAA-846) 48% 100%
B9KLK4 Cereibacter sphaeroides (strain KD131 / KCTC 12085) 48% 100%
B9LKW0 Chloroflexus aurantiacus (strain ATCC 29364 / DSM 637 / Y-400-fl) 46% 100%
B9MM59 Caldicellulosiruptor bescii (strain ATCC BAA-1888 / DSM 6725 / Z-1320) 40% 100%
C0M9N3 Streptococcus equi subsp. equi (strain 4047) 44% 100%
C0MFU5 Streptococcus equi subsp. zooepidemicus (strain H70) 44% 100%
C0QAX9 Desulforapulum autotrophicum (strain ATCC 43914 / DSM 3382 / VKM B-1955 / HRM2) 45% 100%
C0QX38 Brachyspira hyodysenteriae (strain ATCC 49526 / WA1) 43% 100%
C1C7J4 Streptococcus pneumoniae (strain 70585) 44% 100%
C1CEI6 Streptococcus pneumoniae (strain JJA) 44% 100%
C1CKW9 Streptococcus pneumoniae (strain P1031) 44% 100%
C1CR74 Streptococcus pneumoniae (strain Taiwan19F-14) 44% 100%
C1ES77 Bacillus cereus (strain 03BB102) 44% 100%
C1FND0 Clostridium botulinum (strain Kyoto / Type A2) 45% 100%
C1KWH6 Listeria monocytogenes serotype 4b (strain CLIP80459) 43% 100%
C3KVU4 Clostridium botulinum (strain 657 / Type Ba4) 45% 100%
C3LKJ6 Bacillus anthracis (strain CDC 684 / NRRL 3495) 44% 100%
C3MFQ8 Sinorhizobium fredii (strain NBRC 101917 / NGR234) 48% 100%
C3P858 Bacillus anthracis (strain A0248) 44% 100%
C4Z1V6 Lachnospira eligens (strain ATCC 27750 / DSM 3376 / VPI C15-48 / C15-B4) 46% 100%
C4ZBG8 Agathobacter rectalis (strain ATCC 33656 / DSM 3377 / JCM 17463 / KCTC 5835 / VPI 0990) 49% 100%
C5CI89 Kosmotoga olearia (strain ATCC BAA-1733 / DSM 21960 / TBF 19.5.1) 44% 100%
E9B130 Leishmania mexicana (strain MHOM/GT/2001/U1103) 91% 100%
O66164 Sphingobium sp. (strain NBRC 103272 / SYK-6) 47% 100%
P0DF90 Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315) 44% 100%
P0DF91 Streptococcus pyogenes serotype M3 (strain SSI-1) 44% 100%
P0DF92 Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315) 45% 100%
P0DF93 Streptococcus pyogenes serotype M3 (strain SSI-1) 45% 100%
P11586 Homo sapiens 60% 67%
P13419 Clostridium acidurici 47% 100%
P21164 Moorella thermoacetica 50% 100%
P27653 Rattus norvegicus 60% 67%
P28723 Spinacia oleracea 59% 98%
Q02ZS7 Lactococcus lactis subsp. cremoris (strain SK11) 45% 100%
Q038Y4 Lacticaseibacillus paracasei (strain ATCC 334 / BCRC 17002 / CCUG 31169 / CIP 107868 / KCTC 3260 / NRRL B-441) 43% 100%
Q03FM6 Pediococcus pentosaceus (strain ATCC 25745 / CCUG 21536 / LMG 10740 / 183-1w) 43% 100%
Q03L41 Streptococcus thermophilus (strain ATCC BAA-491 / LMD-9) 44% 100%
Q03S45 Levilactobacillus brevis (strain ATCC 367 / BCRC 12310 / CIP 105137 / JCM 1170 / LMG 11437 / NCIMB 947 / NCTC 947) 42% 100%
Q03YB1 Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / DSM 20343 / BCRC 11652 / CCM 1803 / JCM 6124 / NCDO 523 / NBRC 100496 / NCIMB 8023 / NCTC 12954 / NRRL B-1118 / 37Y) 45% 100%
Q043I0 Lactobacillus gasseri (strain ATCC 33323 / DSM 20243 / BCRC 14619 / CIP 102991 / JCM 1131 / KCTC 3163 / NCIMB 11718 / NCTC 13722 / AM63) 40% 100%
Q04AM0 Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC BAA-365 / Lb-18) 41% 100%
Q04FS6 Oenococcus oeni (strain ATCC BAA-331 / PSU-1) 42% 100%
Q04K90 Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) 44% 100%
Q07064 Clostridium cylindrosporum 46% 100%
Q0APT3 Maricaulis maris (strain MCS10) 45% 100%
Q0AX38 Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen) 50% 100%
Q0BW57 Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1) 47% 100%
Q0BX04 Hyphomonas neptunium (strain ATCC 15444) 45% 100%
Q0HMS6 Shewanella sp. (strain MR-4) 48% 100%
Q0HR05 Shewanella sp. (strain MR-7) 48% 100%
Q0SQ82 Clostridium perfringens (strain SM101 / Type A) 45% 100%
Q0TMI3 Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) 45% 100%
Q11G79 Chelativorans sp. (strain BNC1) 47% 100%
Q160C2 Roseobacter denitrificans (strain ATCC 33942 / OCh 114) 45% 100%
Q189R2 Clostridioides difficile (strain 630) 45% 100%
Q18JB5 Haloquadratum walsbyi (strain DSM 16790 / HBSQ001) 42% 100%
Q1AT39 Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129 / PRD-1) 48% 100%
Q1AVP8 Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129 / PRD-1) 48% 100%
Q1AXZ4 Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129 / PRD-1) 48% 100%
Q1DFW5 Myxococcus xanthus (strain DK1622) 41% 100%
Q1GA94 Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / BCRC 10696 / JCM 1002 / NBRC 13953 / NCIMB 11778 / NCTC 12712 / WDCM 00102 / Lb 14) 41% 100%
Q1GE26 Ruegeria sp. (strain TM1040) 46% 100%
Q1GZ16 Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875) 44% 100%
Q1J4C0 Streptococcus pyogenes serotype M4 (strain MGAS10750) 45% 100%
Q1J6F7 Streptococcus pyogenes serotype M4 (strain MGAS10750) 44% 100%
Q1J9F2 Streptococcus pyogenes serotype M12 (strain MGAS2096) 44% 100%
Q1JBM0 Streptococcus pyogenes serotype M12 (strain MGAS2096) 44% 100%
Q1JEK4 Streptococcus pyogenes serotype M2 (strain MGAS10270) 45% 100%
Q1JGN8 Streptococcus pyogenes serotype M2 (strain MGAS10270) 44% 100%
Q1JJK1 Streptococcus pyogenes serotype M12 (strain MGAS9429) 44% 100%
Q1JLK2 Streptococcus pyogenes serotype M12 (strain MGAS9429) 44% 100%
Q1MDG4 Rhizobium leguminosarum bv. viciae (strain 3841) 46% 100%
Q1MPZ9 Lawsonia intracellularis (strain PHE/MN1-00) 43% 100%
Q1WTW0 Ligilactobacillus salivarius (strain UCC118) 44% 100%
Q24ZZ8 Desulfitobacterium hafniense (strain Y51) 47% 100%
Q251P8 Desulfitobacterium hafniense (strain Y51) 48% 100%
Q27772 Spodoptera frugiperda 56% 67%
Q28TR4 Jannaschia sp. (strain CCS1) 46% 100%
Q2FG06 Staphylococcus aureus (strain USA300) 43% 100%
Q2G296 Staphylococcus aureus (strain NCTC 8325 / PS 47) 43% 100%
Q2K5P2 Rhizobium etli (strain CFN 42 / ATCC 51251) 46% 100%
Q2LU82 Syntrophus aciditrophicus (strain SB) 40% 100%
Q2RM91 Moorella thermoacetica (strain ATCC 39073 / JCM 9320) 50% 100%
Q2YTF6 Staphylococcus aureus (strain bovine RF122 / ET3-1) 43% 100%
Q38X32 Latilactobacillus sakei subsp. sakei (strain 23K) 42% 100%
Q3A9K2 Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901) 49% 100%
Q3J047 Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) 49% 100%
Q3K138 Streptococcus agalactiae serotype Ia (strain ATCC 27591 / A909 / CDC SS700) 45% 100%
Q3Z8K3 Dehalococcoides mccartyi (strain ATCC BAA-2266 / KCTC 15142 / 195) 46% 100%
Q3ZX40 Dehalococcoides mccartyi (strain CBDB1) 45% 100%
Q48QZ2 Streptococcus pyogenes serotype M28 (strain MGAS6180) 45% 100%
Q48TE8 Streptococcus pyogenes serotype M28 (strain MGAS6180) 44% 100%
Q4FL49 Pelagibacter ubique (strain HTCC1062) 44% 100%
Q4JVW2 Corynebacterium jeikeium (strain K411) 45% 100%
Q4L776 Staphylococcus haemolyticus (strain JCSC1435) 45% 100%
Q4Q735 Leishmania major 91% 100%
Q59925 Streptococcus mutans serotype c (strain ATCC 700610 / UA159) 44% 100%
Q5E3V8 Aliivibrio fischeri (strain ATCC 700601 / ES114) 47% 100%
Q5FAG1 Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090) 46% 100%
Q5FIU5 Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM) 42% 100%
Q5FJY2 Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM) 41% 100%
Q5HF42 Staphylococcus aureus (strain COL) 43% 100%
Q5HNH4 Staphylococcus epidermidis (strain ATCC 35984 / RP62A) 42% 100%
Q5LD60 Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC 9343 / Onslow) 42% 100%
Q5LNV0 Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) 45% 100%
Q5M083 Streptococcus thermophilus (strain CNRZ 1066) 45% 100%
Q5M4U2 Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) 45% 100%
Q5NQC7 Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) 47% 100%
Q5R8P0 Pongo abelii 60% 67%
Q5V5Y2 Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) 42% 100%
Q5X9K7 Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394) 44% 100%
Q5XC12 Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394) 44% 100%
Q5XZD9 Peptoclostridium acidaminophilum 48% 100%
Q605Q9 Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath) 46% 100%
Q63C61 Bacillus cereus (strain ZK / E33L) 44% 100%
Q64U80 Bacteroides fragilis (strain YCH46) 42% 100%
Q65IA6 Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46) 45% 100%
Q67JH9 Symbiobacterium thermophilum (strain T / IAM 14863) 47% 100%
Q6ABS5 Cutibacterium acnes (strain DSM 16379 / KPA171202) 46% 100%
Q6AL19 Desulfotalea psychrophila (strain LSv54 / DSM 12343) 44% 100%
Q6G8J5 Staphylococcus aureus (strain MSSA476) 43% 100%
Q6GFX6 Staphylococcus aureus (strain MRSA252) 43% 100%
Q6HJK9 Bacillus thuringiensis subsp. konkukian (strain 97-27) 44% 100%
Q6KZM3 Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828) 39% 100%
Q6LNJ0 Photobacterium profundum (strain SS9) 48% 100%
Q6NH87 Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis) 44% 100%
Q71YD9 Listeria monocytogenes serotype 4b (strain F2365) 43% 100%
Q72GY9 Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) 40% 100%
Q739F4 Bacillus cereus (strain ATCC 10987 / NRS 248) 45% 100%
Q73RR6 Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104) 42% 100%
Q74JC1 Lactobacillus johnsonii (strain CNCM I-12250 / La1 / NCC 533) 40% 100%
Q7A535 Staphylococcus aureus (strain N315) 43% 100%
Q7MEE8 Vibrio vulnificus (strain YJ016) 47% 100%
Q7MUZ8 Porphyromonas gingivalis (strain ATCC BAA-308 / W83) 43% 100%
Q7VLW6 Haemophilus ducreyi (strain 35000HP / ATCC 700724) 45% 100%
Q81E87 Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711) 45% 100%
Q81RE1 Bacillus anthracis 44% 100%
Q834D6 Enterococcus faecalis (strain ATCC 700802 / V583) 44% 100%
Q83WS0 Methylorubrum extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1) 46% 100%
Q87HX2 Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) 47% 100%
Q88W76 Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1) 45% 100%
Q891R3 Clostridium tetani (strain Massachusetts / E88) 46% 100%
Q8A9S8 Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) 41% 100%
Q8CNV9 Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200) 42% 100%
Q8D7D8 Vibrio vulnificus (strain CMCP6) 47% 100%
Q8DPL5 Streptococcus pneumoniae (strain ATCC BAA-255 / R6) 44% 100%
Q8DZP5 Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R) 45% 100%
Q8E5E3 Streptococcus agalactiae serotype III (strain NEM316) 45% 100%
Q8EJA7 Shewanella oneidensis (strain MR-1) 47% 100%
Q8EUQ1 Malacoplasma penetrans (strain HF-2) 31% 100%
Q8NW37 Staphylococcus aureus (strain MW2) 43% 100%
Q8NZ49 Streptococcus pyogenes serotype M18 (strain MGAS8232) 44% 100%
Q8P0X5 Streptococcus pyogenes serotype M18 (strain MGAS8232) 44% 100%
Q8R7L3 Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) 47% 100%
Q8RHF4 Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355) 42% 100%
Q8WZJ7 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 59% 66%
Q8XHL4 Clostridium perfringens (strain 13 / Type A) 45% 100%
Q8Y624 Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) 43% 100%
Q922D8 Mus musculus 60% 67%
Q92AD2 Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262) 43% 100%
Q92N42 Rhizobium meliloti (strain 1021) 47% 100%
Q97CL3 Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1) 42% 100%
Q97EB3 Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) 45% 100%
Q97QI2 Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) 44% 100%
Q98HQ4 Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) 47% 100%
Q99TD2 Staphylococcus aureus (strain Mu50 / ATCC 700699) 43% 100%
Q99XR2 Streptococcus pyogenes serotype M1 45% 100%
Q99ZI9 Streptococcus pyogenes serotype M1 44% 100%
Q9CH07 Lactococcus lactis subsp. lactis (strain IL1403) 45% 100%
Q9HI67 Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) 41% 100%
Q9JVY8 Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 / Z2491) 46% 100%
Q9JXY2 Neisseria meningitidis serogroup B (strain MC58) 46% 100%
Q9KLX7 Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) 46% 100%
Q9PQS1 Ureaplasma parvum serovar 3 (strain ATCC 700970) 32% 100%
Q9SPK5 Arabidopsis thaliana 58% 98%
Q9X287 Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) 43% 100%
V5B7B8 Trypanosoma cruzi 76% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS