Succinyl-coa:3-ketoacid-coenzyme a transferase-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

succinyl-coa:3-ketoacid-coenzyme a transferase- like protein

Species:

Leishmania braziliensis

UniProt:

A4HIC0_LEIBR

TriTrypDb:

LbrM.30.1810 , LBRM2903_300023900

Length:

213

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HIC0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HIC0

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	2
GO:0008410	CoA-transferase activity	4	2
GO:0016740	transferase activity	2	2
GO:0016782	transferase activity, transferring sulphur-containing groups	3	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	103	107	PF00082	0.410
DOC_MAPK_DCC_7	201	210	PF00069	0.570
DOC_MAPK_gen_1	161	171	PF00069	0.547
DOC_MAPK_MEF2A_6	75	83	PF00069	0.610
DOC_PP1_RVXF_1	168	174	PF00149	0.547
LIG_14-3-3_CanoR_1	135	144	PF00244	0.547
LIG_CSL_BTD_1	98	101	PF09270	0.610
LIG_FHA_1	200	206	PF00498	0.539
LIG_FHA_2	126	132	PF00498	0.610
LIG_FHA_2	180	186	PF00498	0.610
LIG_GBD_Chelix_1	149	157	PF00786	0.410
LIG_LIR_Apic_2	97	101	PF02991	0.610
LIG_LIR_Gen_1	69	79	PF02991	0.610
LIG_LIR_Nem_3	69	74	PF02991	0.610
LIG_MAD2	135	143	PF02301	0.610
LIG_SH2_STAT5	16	19	PF00017	0.610
LIG_SH3_1	201	207	PF00018	0.552
LIG_SH3_3	201	207	PF00018	0.552
LIG_TRAF2_1	182	185	PF00917	0.610
MOD_CK1_1	60	66	PF00069	0.610
MOD_CK1_1	67	73	PF00069	0.522
MOD_CK2_1	125	131	PF00069	0.610
MOD_CK2_1	179	185	PF00069	0.610
MOD_GlcNHglycan	116	119	PF01048	0.410
MOD_GlcNHglycan	59	62	PF01048	0.410
MOD_GlcNHglycan	66	69	PF01048	0.322
MOD_GlcNHglycan	91	94	PF01048	0.400
MOD_GSK3_1	51	58	PF00069	0.610
MOD_GSK3_1	60	67	PF00069	0.497
MOD_NEK2_1	114	119	PF00069	0.610
MOD_NEK2_1	125	130	PF00069	0.472
MOD_NEK2_1	57	62	PF00069	0.610
MOD_NEK2_1	79	84	PF00069	0.585
MOD_NEK2_1	87	92	PF00069	0.535
MOD_Plk_1	79	85	PF00069	0.547
MOD_Plk_2-3	179	185	PF00069	0.610
MOD_Plk_4	60	66	PF00069	0.610
MOD_Plk_4	79	85	PF00069	0.372
MOD_Plk_4	94	100	PF00069	0.469
MOD_SUMO_rev_2	126	134	PF00179	0.610
MOD_SUMO_rev_2	179	188	PF00179	0.547

Homologs


Protein	Taxonomy	Sequence identity	Coverage
B0RVK3	Xanthomonas campestris pv. campestris (strain B100)	58%	100%
O34466	Bacillus subtilis (strain 168)	48%	98%
P0A101	Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)	48%	100%
P0A102	Pseudomonas putida	48%	100%
P0C7I8	Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)	58%	100%
P23673	Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)	42%	96%
P42316	Bacillus subtilis (strain 168)	56%	99%
P44874	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	43%	96%
P56007	Helicobacter pylori (strain ATCC 700392 / 26695)	53%	100%
P63651	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	53%	98%
P76459	Escherichia coli (strain K12)	45%	99%
P9WPW2	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	53%	98%
P9WPW3	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	53%	98%
Q59091	Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)	40%	98%
Q9ZLE4	Helicobacter pylori (strain J99 / ATCC 700824)	53%	100%