LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HIA5_LEIBR
TriTrypDb:
LbrM.30.1660 , LBRM2903_300022300 *
Length:
532

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HIA5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HIA5

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 198 202 PF00656 0.622
CLV_NRD_NRD_1 123 125 PF00675 0.506
CLV_NRD_NRD_1 287 289 PF00675 0.538
CLV_NRD_NRD_1 375 377 PF00675 0.587
CLV_PCSK_FUR_1 373 377 PF00082 0.634
CLV_PCSK_KEX2_1 123 125 PF00082 0.506
CLV_PCSK_KEX2_1 287 289 PF00082 0.513
CLV_PCSK_KEX2_1 361 363 PF00082 0.554
CLV_PCSK_KEX2_1 375 377 PF00082 0.496
CLV_PCSK_KEX2_1 379 381 PF00082 0.458
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P973 Leptomonas seymouri 44% 100%
A0A3Q8IFL5 Leishmania donovani 75% 100%
A0A3R7NW81 Trypanosoma rangeli 25% 100%
A4I5I9 Leishmania infantum 74% 100%
E9B0T4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 75% 100%
Q4Q7E4 Leishmania major 72% 100%
V5BZ01 Trypanosoma cruzi 26% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS