PSP1 C-terminal domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

PSP1 C-terminal conserved region, putative

Species:

Leishmania braziliensis

UniProt:

A4HI89_LEIBR

TriTrypDb:

LbrM.30.1490 , LBRM2903_300020500 , LBRM2903_300020600

Length:

877

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HI89

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HI89

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	654	658	PF00656	0.541
CLV_NRD_NRD_1	230	232	PF00675	0.800
CLV_NRD_NRD_1	261	263	PF00675	0.536
CLV_NRD_NRD_1	314	316	PF00675	0.699
CLV_NRD_NRD_1	510	512	PF00675	0.605
CLV_NRD_NRD_1	561	563	PF00675	0.719
CLV_NRD_NRD_1	628	630	PF00675	0.745
CLV_NRD_NRD_1	638	640	PF00675	0.741
CLV_NRD_NRD_1	661	663	PF00675	0.532
CLV_NRD_NRD_1	778	780	PF00675	0.716
CLV_NRD_NRD_1	790	792	PF00675	0.499
CLV_PCSK_FUR_1	705	709	PF00082	0.518
CLV_PCSK_KEX2_1	230	232	PF00082	0.814
CLV_PCSK_KEX2_1	261	263	PF00082	0.536
CLV_PCSK_KEX2_1	314	316	PF00082	0.699
CLV_PCSK_KEX2_1	510	512	PF00082	0.605
CLV_PCSK_KEX2_1	561	563	PF00082	0.719
CLV_PCSK_KEX2_1	628	630	PF00082	0.745
CLV_PCSK_KEX2_1	638	640	PF00082	0.741
CLV_PCSK_KEX2_1	707	709	PF00082	0.791
CLV_PCSK_KEX2_1	790	792	PF00082	0.244
CLV_PCSK_PC1ET2_1	707	709	PF00082	0.791
CLV_PCSK_PC7_1	703	709	PF00082	0.516
CLV_PCSK_SKI1_1	336	340	PF00082	0.565
CLV_PCSK_SKI1_1	430	434	PF00082	0.803
CLV_PCSK_SKI1_1	435	439	PF00082	0.539
CLV_PCSK_SKI1_1	482	486	PF00082	0.562
CLV_PCSK_SKI1_1	56	60	PF00082	0.580
CLV_PCSK_SKI1_1	682	686	PF00082	0.742
CLV_PCSK_SKI1_1	707	711	PF00082	0.717
CLV_PCSK_SKI1_1	721	725	PF00082	0.720
CLV_PCSK_SKI1_1	809	813	PF00082	0.300
CLV_PCSK_SKI1_1	85	89	PF00082	0.544
CLV_PCSK_SKI1_1	871	875	PF00082	0.369
CLV_Separin_Metazoa	204	208	PF03568	0.637
DOC_CKS1_1	128	133	PF01111	0.805
DOC_CKS1_1	189	194	PF01111	0.644
DOC_CKS1_1	296	301	PF01111	0.806
DOC_CYCLIN_RxL_1	718	728	PF00134	0.772
DOC_CYCLIN_yClb5_NLxxxL_5	811	820	PF00134	0.244
DOC_CYCLIN_yCln2_LP_2	89	95	PF00134	0.803
DOC_MAPK_gen_1	314	321	PF00069	0.556
DOC_MAPK_gen_1	336	346	PF00069	0.560
DOC_MAPK_gen_1	561	571	PF00069	0.718
DOC_MAPK_gen_1	662	669	PF00069	0.532
DOC_MAPK_gen_1	809	818	PF00069	0.411
DOC_MAPK_MEF2A_6	314	321	PF00069	0.556
DOC_MAPK_MEF2A_6	565	573	PF00069	0.552
DOC_PP1_RVXF_1	860	867	PF00149	0.411
DOC_PP2B_LxvP_1	485	488	PF13499	0.558
DOC_PP2B_LxvP_1	58	61	PF13499	0.571
DOC_PP4_MxPP_1	446	449	PF00568	0.561
DOC_USP7_MATH_1	122	126	PF00917	0.752
DOC_USP7_MATH_1	216	220	PF00917	0.748
DOC_USP7_MATH_1	226	230	PF00917	0.667
DOC_USP7_MATH_1	362	366	PF00917	0.750
DOC_USP7_MATH_1	40	44	PF00917	0.796
DOC_USP7_MATH_1	488	492	PF00917	0.651
DOC_USP7_MATH_1	500	504	PF00917	0.634
DOC_USP7_MATH_1	533	537	PF00917	0.748
DOC_USP7_MATH_1	564	568	PF00917	0.797
DOC_USP7_MATH_1	604	608	PF00917	0.772
DOC_USP7_MATH_1	618	622	PF00917	0.681
DOC_USP7_MATH_1	855	859	PF00917	0.298
DOC_WW_Pin1_4	116	121	PF00397	0.758
DOC_WW_Pin1_4	127	132	PF00397	0.719
DOC_WW_Pin1_4	171	176	PF00397	0.702
DOC_WW_Pin1_4	188	193	PF00397	0.686
DOC_WW_Pin1_4	211	216	PF00397	0.687
DOC_WW_Pin1_4	222	227	PF00397	0.727
DOC_WW_Pin1_4	250	255	PF00397	0.527
DOC_WW_Pin1_4	27	32	PF00397	0.800
DOC_WW_Pin1_4	273	278	PF00397	0.683
DOC_WW_Pin1_4	295	300	PF00397	0.706
DOC_WW_Pin1_4	331	336	PF00397	0.554
DOC_WW_Pin1_4	547	552	PF00397	0.695
DOC_WW_Pin1_4	685	690	PF00397	0.506
DOC_WW_Pin1_4	69	74	PF00397	0.761
DOC_WW_Pin1_4	739	744	PF00397	0.600
DOC_WW_Pin1_4	760	765	PF00397	0.597
DOC_WW_Pin1_4	88	93	PF00397	0.558
LIG_14-3-3_CanoR_1	107	113	PF00244	0.562
LIG_14-3-3_CanoR_1	279	283	PF00244	0.801
LIG_14-3-3_CanoR_1	303	309	PF00244	0.744
LIG_14-3-3_CanoR_1	409	416	PF00244	0.840
LIG_14-3-3_CanoR_1	419	423	PF00244	0.770
LIG_14-3-3_CanoR_1	441	447	PF00244	0.821
LIG_14-3-3_CanoR_1	56	61	PF00244	0.800
LIG_14-3-3_CanoR_1	590	595	PF00244	0.842
LIG_14-3-3_CanoR_1	6	14	PF00244	0.727
LIG_14-3-3_CanoR_1	619	623	PF00244	0.573
LIG_14-3-3_CanoR_1	662	670	PF00244	0.659
LIG_Actin_WH2_2	766	781	PF00022	0.707
LIG_APCC_ABBA_1	783	788	PF00400	0.244
LIG_BRCT_BRCA1_1	705	709	PF00533	0.518
LIG_BRCT_BRCA1_1	821	825	PF00533	0.306
LIG_FHA_1	106	112	PF00498	0.792
LIG_FHA_1	193	199	PF00498	0.671
LIG_FHA_1	321	327	PF00498	0.696
LIG_FHA_1	568	574	PF00498	0.552
LIG_FHA_1	713	719	PF00498	0.761
LIG_FHA_1	760	766	PF00498	0.457
LIG_FHA_1	800	806	PF00498	0.453
LIG_FHA_1	846	852	PF00498	0.271
LIG_FHA_1	855	861	PF00498	0.224
LIG_FHA_2	154	160	PF00498	0.689
LIG_FHA_2	688	694	PF00498	0.699
LIG_LIR_Apic_2	465	470	PF02991	0.648
LIG_LIR_Apic_2	481	486	PF02991	0.560
LIG_LIR_Gen_1	21	31	PF02991	0.554
LIG_LIR_Gen_1	748	756	PF02991	0.614
LIG_LIR_Nem_3	190	196	PF02991	0.768
LIG_LIR_Nem_3	21	27	PF02991	0.555
LIG_LIR_Nem_3	748	752	PF02991	0.618
LIG_LIR_Nem_3	821	827	PF02991	0.352
LIG_MAD2	837	845	PF02301	0.244
LIG_MLH1_MIPbox_1	821	825	PF16413	0.274
LIG_PCNA_yPIPBox_3	194	206	PF02747	0.634
LIG_Pex14_2	164	168	PF04695	0.787
LIG_PTB_Apo_2	812	819	PF02174	0.244
LIG_RPA_C_Fungi	634	646	PF08784	0.563
LIG_SH2_CRK	483	487	PF00017	0.560
LIG_SH2_CRK	836	840	PF00017	0.411
LIG_SH2_NCK_1	467	471	PF00017	0.774
LIG_SH2_NCK_1	472	476	PF00017	0.687
LIG_SH2_NCK_1	483	487	PF00017	0.560
LIG_SH2_NCK_1	749	753	PF00017	0.697
LIG_SH2_SRC	467	470	PF00017	0.724
LIG_SH2_SRC	749	752	PF00017	0.698
LIG_SH2_STAP1	452	456	PF00017	0.740
LIG_SH2_STAP1	766	770	PF00017	0.696
LIG_SH2_STAT3	196	199	PF00017	0.762
LIG_SH2_STAT3	766	769	PF00017	0.426
LIG_SH2_STAT5	320	323	PF00017	0.695
LIG_SH2_STAT5	733	736	PF00017	0.533
LIG_SH2_STAT5	738	741	PF00017	0.559
LIG_SH2_STAT5	766	769	PF00017	0.441
LIG_SH2_STAT5	804	807	PF00017	0.407
LIG_SH2_STAT5	824	827	PF00017	0.183
LIG_SH2_STAT5	852	855	PF00017	0.295
LIG_SH3_2	548	553	PF14604	0.580
LIG_SH3_2	585	590	PF14604	0.782
LIG_SH3_3	267	273	PF00018	0.768
LIG_SH3_3	484	490	PF00018	0.611
LIG_SH3_3	545	551	PF00018	0.677
LIG_SH3_3	552	558	PF00018	0.708
LIG_SH3_3	582	588	PF00018	0.787
LIG_SH3_3	619	625	PF00018	0.606
LIG_SUMO_SIM_anti_2	278	284	PF11976	0.534
LIG_SUMO_SIM_anti_2	664	671	PF11976	0.702
LIG_SUMO_SIM_par_1	518	525	PF11976	0.756
LIG_SUMO_SIM_par_1	567	572	PF11976	0.718
LIG_TRAF2_1	201	204	PF00917	0.619
LIG_TRAF2_1	577	580	PF00917	0.561
LIG_TRFH_1	483	487	PF08558	0.560
LIG_TYR_ITIM	747	752	PF00017	0.585
LIG_TYR_ITIM	834	839	PF00017	0.411
LIG_WRC_WIRS_1	165	170	PF05994	0.569
LIG_WRC_WIRS_1	210	215	PF05994	0.741
LIG_WRC_WIRS_1	824	829	PF05994	0.352
LIG_WW_1	449	452	PF00397	0.727
LIG_WW_3	486	490	PF00397	0.561
MOD_CDC14_SPxK_1	174	177	PF00782	0.532
MOD_CDC14_SPxK_1	550	553	PF00782	0.582
MOD_CDC14_SPxK_1	742	745	PF00782	0.444
MOD_CDK_SPK_2	295	300	PF00069	0.539
MOD_CDK_SPK_2	331	336	PF00069	0.554
MOD_CDK_SPxK_1	127	133	PF00069	0.663
MOD_CDK_SPxK_1	171	177	PF00069	0.736
MOD_CDK_SPxK_1	188	194	PF00069	0.594
MOD_CDK_SPxK_1	211	217	PF00069	0.690
MOD_CDK_SPxK_1	273	279	PF00069	0.685
MOD_CDK_SPxK_1	547	553	PF00069	0.580
MOD_CDK_SPxK_1	739	745	PF00069	0.465
MOD_CK1_1	105	111	PF00069	0.634
MOD_CK1_1	167	173	PF00069	0.711
MOD_CK1_1	250	256	PF00069	0.712
MOD_CK1_1	331	337	PF00069	0.580
MOD_CK1_1	367	373	PF00069	0.586
MOD_CK1_1	417	423	PF00069	0.845
MOD_CK1_1	42	48	PF00069	0.732
MOD_CK1_1	473	479	PF00069	0.755
MOD_CK1_1	567	573	PF00069	0.552
MOD_CK1_1	606	612	PF00069	0.733
MOD_CK1_1	63	69	PF00069	0.846
MOD_CK1_1	651	657	PF00069	0.611
MOD_CK1_1	697	703	PF00069	0.650
MOD_CK2_1	153	159	PF00069	0.642
MOD_CK2_1	167	173	PF00069	0.648
MOD_CK2_1	287	293	PF00069	0.686
MOD_CK2_1	372	378	PF00069	0.811
MOD_CK2_1	687	693	PF00069	0.488
MOD_Cter_Amidation	259	262	PF01082	0.538
MOD_Cter_Amidation	508	511	PF01082	0.641
MOD_GlcNHglycan	136	139	PF01048	0.598
MOD_GlcNHglycan	169	172	PF01048	0.710
MOD_GlcNHglycan	185	188	PF01048	0.700
MOD_GlcNHglycan	20	24	PF01048	0.660
MOD_GlcNHglycan	309	312	PF01048	0.665
MOD_GlcNHglycan	353	356	PF01048	0.678
MOD_GlcNHglycan	371	374	PF01048	0.706
MOD_GlcNHglycan	386	389	PF01048	0.602
MOD_GlcNHglycan	416	419	PF01048	0.770
MOD_GlcNHglycan	42	45	PF01048	0.826
MOD_GlcNHglycan	473	476	PF01048	0.660
MOD_GlcNHglycan	592	595	PF01048	0.834
MOD_GlcNHglycan	605	609	PF01048	0.740
MOD_GlcNHglycan	625	628	PF01048	0.696
MOD_GlcNHglycan	641	644	PF01048	0.622
MOD_GlcNHglycan	65	69	PF01048	0.743
MOD_GlcNHglycan	653	656	PF01048	0.648
MOD_GlcNHglycan	8	11	PF01048	0.810
MOD_GlcNHglycan	96	99	PF01048	0.675
MOD_GSK3_1	101	108	PF00069	0.595
MOD_GSK3_1	123	130	PF00069	0.723
MOD_GSK3_1	167	174	PF00069	0.782
MOD_GSK3_1	183	190	PF00069	0.559
MOD_GSK3_1	19	26	PF00069	0.803
MOD_GSK3_1	222	229	PF00069	0.737
MOD_GSK3_1	294	301	PF00069	0.704
MOD_GSK3_1	364	371	PF00069	0.751
MOD_GSK3_1	39	46	PF00069	0.499
MOD_GSK3_1	410	417	PF00069	0.789
MOD_GSK3_1	448	455	PF00069	0.704
MOD_GSK3_1	470	477	PF00069	0.750
MOD_GSK3_1	542	549	PF00069	0.652
MOD_GSK3_1	56	63	PF00069	0.841
MOD_GSK3_1	569	576	PF00069	0.551
MOD_GSK3_1	603	610	PF00069	0.791
MOD_GSK3_1	687	694	PF00069	0.609
MOD_GSK3_1	703	710	PF00069	0.726
MOD_GSK3_1	713	720	PF00069	0.751
MOD_GSK3_1	760	767	PF00069	0.539
MOD_GSK3_1	819	826	PF00069	0.400
MOD_N-GLC_1	114	119	PF02516	0.829
MOD_N-GLC_1	33	38	PF02516	0.711
MOD_N-GLC_1	350	355	PF02516	0.576
MOD_N-GLC_1	610	615	PF02516	0.568
MOD_N-GLC_1	685	690	PF02516	0.673
MOD_N-GLC_1	855	860	PF02516	0.235
MOD_NEK2_1	123	128	PF00069	0.550
MOD_NEK2_1	152	157	PF00069	0.630
MOD_NEK2_1	25	30	PF00069	0.826
MOD_NEK2_1	573	578	PF00069	0.553
MOD_NEK2_1	758	763	PF00069	0.414
MOD_NEK2_1	811	816	PF00069	0.431
MOD_NEK2_1	827	832	PF00069	0.311
MOD_NEK2_1	93	98	PF00069	0.538
MOD_NEK2_2	247	252	PF00069	0.550
MOD_NEK2_2	533	538	PF00069	0.583
MOD_PIKK_1	185	191	PF00454	0.669
MOD_PIKK_1	364	370	PF00454	0.595
MOD_PIKK_1	48	54	PF00454	0.826
MOD_PIKK_1	542	548	PF00454	0.750
MOD_PIKK_1	633	639	PF00454	0.797
MOD_PIKK_1	736	742	PF00454	0.562
MOD_PKA_1	638	644	PF00069	0.564
MOD_PKA_1	662	668	PF00069	0.530
MOD_PKA_1	707	713	PF00069	0.791
MOD_PKA_2	106	112	PF00069	0.710
MOD_PKA_2	132	138	PF00069	0.578
MOD_PKA_2	278	284	PF00069	0.801
MOD_PKA_2	302	308	PF00069	0.745
MOD_PKA_2	408	414	PF00069	0.850
MOD_PKA_2	418	424	PF00069	0.763
MOD_PKA_2	48	54	PF00069	0.826
MOD_PKA_2	488	494	PF00069	0.583
MOD_PKA_2	618	624	PF00069	0.647
MOD_PKA_2	638	644	PF00069	0.759
MOD_PKA_2	661	667	PF00069	0.657
MOD_PKA_2	707	713	PF00069	0.791
MOD_PKA_2	78	84	PF00069	0.781
MOD_PKB_1	54	62	PF00069	0.797
MOD_PKB_1	701	709	PF00069	0.513
MOD_Plk_1	19	25	PF00069	0.668
MOD_Plk_1	533	539	PF00069	0.583
MOD_Plk_1	579	585	PF00069	0.570
MOD_Plk_1	855	861	PF00069	0.235
MOD_Plk_4	123	129	PF00069	0.817
MOD_Plk_4	247	253	PF00069	0.689
MOD_Plk_4	263	269	PF00069	0.710
MOD_Plk_4	278	284	PF00069	0.472
MOD_Plk_4	390	396	PF00069	0.665
MOD_Plk_4	500	506	PF00069	0.612
MOD_Plk_4	564	570	PF00069	0.551
MOD_Plk_4	694	700	PF00069	0.614
MOD_Plk_4	713	719	PF00069	0.723
MOD_Plk_4	729	735	PF00069	0.527
MOD_Plk_4	819	825	PF00069	0.411
MOD_ProDKin_1	116	122	PF00069	0.753
MOD_ProDKin_1	127	133	PF00069	0.720
MOD_ProDKin_1	171	177	PF00069	0.703
MOD_ProDKin_1	188	194	PF00069	0.686
MOD_ProDKin_1	211	217	PF00069	0.690
MOD_ProDKin_1	222	228	PF00069	0.725
MOD_ProDKin_1	250	256	PF00069	0.528
MOD_ProDKin_1	27	33	PF00069	0.801
MOD_ProDKin_1	273	279	PF00069	0.685
MOD_ProDKin_1	295	301	PF00069	0.705
MOD_ProDKin_1	331	337	PF00069	0.554
MOD_ProDKin_1	547	553	PF00069	0.697
MOD_ProDKin_1	685	691	PF00069	0.500
MOD_ProDKin_1	69	75	PF00069	0.761
MOD_ProDKin_1	739	745	PF00069	0.602
MOD_ProDKin_1	760	766	PF00069	0.593
MOD_ProDKin_1	88	94	PF00069	0.559
TRG_DiLeu_BaEn_3	159	165	PF01217	0.515
TRG_ENDOCYTIC_2	245	248	PF00928	0.685
TRG_ENDOCYTIC_2	749	752	PF00928	0.611
TRG_ENDOCYTIC_2	824	827	PF00928	0.387
TRG_ENDOCYTIC_2	836	839	PF00928	0.411
TRG_ER_diArg_1	313	315	PF00400	0.699
TRG_ER_diArg_1	510	512	PF00400	0.605
TRG_ER_diArg_1	560	562	PF00400	0.725
TRG_ER_diArg_1	628	630	PF00400	0.745
TRG_ER_diArg_1	77	80	PF00400	0.829
TRG_NES_CRM1_1	863	876	PF08389	0.274
TRG_Pf-PMV_PEXEL_1	430	434	PF00026	0.803
TRG_Pf-PMV_PEXEL_1	795	799	PF00026	0.411
TRG_Pf-PMV_PEXEL_1	859	863	PF00026	0.244

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IA65	Leptomonas seymouri	44%	88%
A0A3S7X3A5	Leishmania donovani	68%	96%
A4I5G8	Leishmania infantum	68%	83%
E9B0R6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	67%	97%
Q4Q7G7	Leishmania major	69%	100%