PCI domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HHY7_LEIBR

TriTrypDb:

LbrM.30.0440

Length:

508

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HHY7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HHY7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	129	133	PF00656	0.809
CLV_C14_Caspase3-7	358	362	PF00656	0.811
CLV_NRD_NRD_1	458	460	PF00675	0.640
CLV_NRD_NRD_1	472	474	PF00675	0.449
CLV_NRD_NRD_1	505	507	PF00675	0.722
CLV_PCSK_KEX2_1	472	474	PF00082	0.694
CLV_PCSK_SKI1_1	217	221	PF00082	0.663
CLV_PCSK_SKI1_1	314	318	PF00082	0.814
CLV_PCSK_SKI1_1	334	338	PF00082	0.481
CLV_PCSK_SKI1_1	354	358	PF00082	0.471
CLV_PCSK_SKI1_1	367	371	PF00082	0.603
CLV_PCSK_SKI1_1	460	464	PF00082	0.638
CLV_PCSK_SKI1_1	499	503	PF00082	0.680
CLV_PCSK_SKI1_1	99	103	PF00082	0.659
DEG_COP1_1	393	401	PF00400	0.819
DEG_SCF_FBW7_1	310	315	PF00400	0.799
DEG_SCF_FBW7_1	328	335	PF00400	0.510
DOC_AGCK_PIF_3	505	508	PF00069	0.736
DOC_MAPK_gen_1	459	466	PF00069	0.638
DOC_MAPK_MEF2A_6	459	466	PF00069	0.638
DOC_MAPK_NFAT4_5	459	467	PF00069	0.641
DOC_PIKK_1	18	26	PF02985	0.840
DOC_PP1_RVXF_1	42	49	PF00149	0.825
DOC_PP4_FxxP_1	165	168	PF00568	0.824
DOC_PP4_FxxP_1	396	399	PF00568	0.818
DOC_PP4_FxxP_1	485	488	PF00568	0.789
DOC_USP7_MATH_1	275	279	PF00917	0.843
DOC_USP7_MATH_1	280	284	PF00917	0.753
DOC_USP7_MATH_1	298	302	PF00917	0.486
DOC_USP7_MATH_1	312	316	PF00917	0.559
DOC_USP7_MATH_1	332	336	PF00917	0.480
DOC_USP7_MATH_1	346	350	PF00917	0.581
DOC_USP7_MATH_1	406	410	PF00917	0.820
DOC_USP7_MATH_1	427	431	PF00917	0.746
DOC_USP7_MATH_1	7	11	PF00917	0.843
DOC_USP7_UBL2_3	503	507	PF12436	0.709
DOC_WW_Pin1_4	271	276	PF00397	0.856
DOC_WW_Pin1_4	308	313	PF00397	0.800
DOC_WW_Pin1_4	328	333	PF00397	0.476
LIG_14-3-3_CanoR_1	153	157	PF00244	0.807
LIG_14-3-3_CanoR_1	161	165	PF00244	0.671
LIG_14-3-3_CanoR_1	347	353	PF00244	0.828
LIG_14-3-3_CanoR_1	367	376	PF00244	0.479
LIG_14-3-3_CanoR_1	426	434	PF00244	0.730
LIG_14-3-3_CanoR_1	473	479	PF00244	0.714
LIG_APCC_ABBA_1	27	32	PF00400	0.839
LIG_BIR_II_1	1	5	PF00653	0.827
LIG_FHA_1	121	127	PF00498	0.648
LIG_FHA_1	239	245	PF00498	0.625
LIG_FHA_1	346	352	PF00498	0.824
LIG_FHA_1	439	445	PF00498	0.646
LIG_FHA_1	491	497	PF00498	0.725
LIG_FHA_1	77	83	PF00498	0.828
LIG_FHA_2	475	481	PF00498	0.728
LIG_FHA_2	51	57	PF00498	0.826
LIG_LIR_Apic_2	162	168	PF02991	0.814
LIG_LIR_Apic_2	393	399	PF02991	0.817
LIG_LIR_Apic_2	484	488	PF02991	0.786
LIG_LIR_Gen_1	428	439	PF02991	0.688
LIG_LIR_Gen_1	52	59	PF02991	0.823
LIG_LIR_Nem_3	315	320	PF02991	0.816
LIG_LIR_Nem_3	335	340	PF02991	0.479
LIG_LIR_Nem_3	428	434	PF02991	0.716
LIG_LIR_Nem_3	502	508	PF02991	0.711
LIG_LIR_Nem_3	52	58	PF02991	0.823
LIG_Pex14_2	313	317	PF04695	0.811
LIG_Pex14_2	333	337	PF04695	0.483
LIG_SH2_NCK_1	476	480	PF00017	0.726
LIG_SH2_NCK_1	55	59	PF00017	0.824
LIG_SH2_STAT5	476	479	PF00017	0.721
LIG_SH3_3	1	7	PF00018	0.825
LIG_SH3_3	165	171	PF00018	0.819
LIG_SH3_3	337	343	PF00018	0.823
LIG_SH3_3	396	402	PF00018	0.817
LIG_SUMO_SIM_anti_2	432	438	PF11976	0.663
LIG_SUMO_SIM_par_1	435	442	PF11976	0.647
LIG_TYR_ITSM	51	58	PF00017	0.824
MOD_CDK_SPxK_1	308	314	PF00069	0.802
MOD_CDK_SPxK_1	328	334	PF00069	0.476
MOD_CK1_1	111	117	PF00069	0.650
MOD_CK1_1	225	231	PF00069	0.683
MOD_CK1_1	308	314	PF00069	0.802
MOD_CK1_1	379	385	PF00069	0.828
MOD_CK1_1	397	403	PF00069	0.501
MOD_CK1_1	40	46	PF00069	0.833
MOD_CK1_1	413	419	PF00069	0.532
MOD_CK1_1	425	431	PF00069	0.549
MOD_CK1_1	438	444	PF00069	0.420
MOD_CK2_1	169	175	PF00069	0.812
MOD_CK2_1	189	195	PF00069	0.485
MOD_CK2_1	385	391	PF00069	0.822
MOD_CK2_1	474	480	PF00069	0.721
MOD_CK2_1	50	56	PF00069	0.825
MOD_GlcNHglycan	128	132	PF01048	0.784
MOD_GlcNHglycan	191	194	PF01048	0.837
MOD_GlcNHglycan	202	205	PF01048	0.559
MOD_GlcNHglycan	224	227	PF01048	0.687
MOD_GlcNHglycan	252	255	PF01048	0.806
MOD_GlcNHglycan	261	264	PF01048	0.679
MOD_GlcNHglycan	300	303	PF01048	0.797
MOD_GlcNHglycan	314	317	PF01048	0.566
MOD_GlcNHglycan	334	337	PF01048	0.481
MOD_GlcNHglycan	348	351	PF01048	0.581
MOD_GlcNHglycan	378	381	PF01048	0.835
MOD_GlcNHglycan	387	390	PF01048	0.664
MOD_GlcNHglycan	408	411	PF01048	0.820
MOD_GlcNHglycan	62	65	PF01048	0.826
MOD_GlcNHglycan	66	69	PF01048	0.788
MOD_GSK3_1	222	229	PF00069	0.691
MOD_GSK3_1	259	266	PF00069	0.842
MOD_GSK3_1	271	278	PF00069	0.643
MOD_GSK3_1	294	301	PF00069	0.804
MOD_GSK3_1	308	315	PF00069	0.555
MOD_GSK3_1	328	335	PF00069	0.475
MOD_GSK3_1	33	40	PF00069	0.836
MOD_GSK3_1	406	413	PF00069	0.818
MOD_GSK3_1	425	432	PF00069	0.417
MOD_GSK3_1	60	67	PF00069	0.832
MOD_N-GLC_1	410	415	PF02516	0.815
MOD_NEK2_1	244	249	PF00069	0.693
MOD_NEK2_1	259	264	PF00069	0.573
MOD_NEK2_1	293	298	PF00069	0.808
MOD_NEK2_1	369	374	PF00069	0.829
MOD_NEK2_1	376	381	PF00069	0.714
MOD_NEK2_2	108	113	PF00069	0.686
MOD_NEK2_2	226	231	PF00069	0.677
MOD_PIKK_1	382	388	PF00454	0.820
MOD_PIKK_1	76	82	PF00454	0.831
MOD_PKA_1	121	127	PF00069	0.648
MOD_PKA_1	239	245	PF00069	0.625
MOD_PKA_1	50	56	PF00069	0.825
MOD_PKA_2	152	158	PF00069	0.810
MOD_PKA_2	160	166	PF00069	0.673
MOD_PKA_2	244	250	PF00069	0.706
MOD_PKA_2	346	352	PF00069	0.824
MOD_PKA_2	425	431	PF00069	0.759
MOD_Plk_1	36	42	PF00069	0.838
MOD_Plk_1	392	398	PF00069	0.820
MOD_Plk_4	121	127	PF00069	0.648
MOD_Plk_4	160	166	PF00069	0.813
MOD_Plk_4	239	245	PF00069	0.625
MOD_Plk_4	280	286	PF00069	0.838
MOD_Plk_4	352	358	PF00069	0.825
MOD_Plk_4	435	441	PF00069	0.648
MOD_Plk_4	492	498	PF00069	0.715
MOD_Plk_4	50	56	PF00069	0.825
MOD_ProDKin_1	271	277	PF00069	0.856
MOD_ProDKin_1	308	314	PF00069	0.802
MOD_ProDKin_1	328	334	PF00069	0.476
MOD_SUMO_for_1	451	454	PF00179	0.648
MOD_SUMO_for_1	71	74	PF00179	0.841
MOD_SUMO_rev_2	278	283	PF00179	0.843
MOD_SUMO_rev_2	365	375	PF00179	0.826
TRG_DiLeu_BaEn_1	465	470	PF01217	0.651
TRG_DiLeu_BaEn_3	175	181	PF01217	0.824
TRG_ENDOCYTIC_2	55	58	PF00928	0.825
TRG_NES_CRM1_1	454	465	PF08389	0.639
TRG_Pf-PMV_PEXEL_1	367	371	PF00026	0.831