| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 9 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 11 |
| NetGPI | no | yes: 0, no: 11 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005730 | nucleolus | 5 | 1 |
| GO:0043226 | organelle | 2 | 1 |
| GO:0043228 | non-membrane-bounded organelle | 3 | 1 |
| GO:0043229 | intracellular organelle | 3 | 1 |
| GO:0043232 | intracellular non-membrane-bounded organelle | 4 | 1 |
| GO:0110165 | cellular anatomical entity | 1 | 2 |
| GO:0016020 | membrane | 2 | 1 |
Related structures:
AlphaFold database: A4HHW5
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0000154 | rRNA modification | 6 | 1 |
| GO:0001510 | RNA methylation | 4 | 1 |
| GO:0006139 | nucleobase-containing compound metabolic process | 3 | 1 |
| GO:0006364 | rRNA processing | 8 | 1 |
| GO:0006396 | RNA processing | 6 | 1 |
| GO:0006725 | cellular aromatic compound metabolic process | 3 | 1 |
| GO:0006807 | nitrogen compound metabolic process | 2 | 1 |
| GO:0008152 | metabolic process | 1 | 1 |
| GO:0009451 | RNA modification | 5 | 1 |
| GO:0009987 | cellular process | 1 | 1 |
| GO:0016070 | RNA metabolic process | 5 | 1 |
| GO:0016072 | rRNA metabolic process | 7 | 1 |
| GO:0031167 | rRNA methylation | 5 | 1 |
| GO:0032259 | methylation | 2 | 1 |
| GO:0034470 | ncRNA processing | 7 | 1 |
| GO:0034641 | cellular nitrogen compound metabolic process | 3 | 1 |
| GO:0034660 | ncRNA metabolic process | 6 | 1 |
| GO:0043170 | macromolecule metabolic process | 3 | 1 |
| GO:0043412 | macromolecule modification | 4 | 1 |
| GO:0043414 | macromolecule methylation | 3 | 1 |
| GO:0044237 | cellular metabolic process | 2 | 1 |
| GO:0044238 | primary metabolic process | 2 | 1 |
| GO:0044260 | obsolete cellular macromolecule metabolic process | 3 | 1 |
| GO:0046483 | heterocycle metabolic process | 3 | 1 |
| GO:0071704 | organic substance metabolic process | 2 | 1 |
| GO:0090304 | nucleic acid metabolic process | 4 | 1 |
| GO:1901360 | organic cyclic compound metabolic process | 3 | 1 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity | 6 | 12 |
| GO:0003676 | nucleic acid binding | 3 | 12 |
| GO:0003723 | RNA binding | 4 | 12 |
| GO:0003824 | catalytic activity | 1 | 12 |
| GO:0005488 | binding | 1 | 12 |
| GO:0008168 | methyltransferase activity | 4 | 12 |
| GO:0008170 | N-methyltransferase activity | 5 | 12 |
| GO:0008173 | RNA methyltransferase activity | 4 | 12 |
| GO:0008649 | rRNA methyltransferase activity | 5 | 12 |
| GO:0008757 | S-adenosylmethionine-dependent methyltransferase activity | 5 | 12 |
| GO:0016433 | rRNA (adenine) methyltransferase activity | 6 | 12 |
| GO:0016740 | transferase activity | 2 | 12 |
| GO:0016741 | transferase activity, transferring one-carbon groups | 3 | 12 |
| GO:0097159 | organic cyclic compound binding | 2 | 12 |
| GO:0140098 | catalytic activity, acting on RNA | 3 | 12 |
| GO:0140102 | catalytic activity, acting on a rRNA | 4 | 12 |
| GO:0140640 | catalytic activity, acting on a nucleic acid | 2 | 12 |
| GO:1901363 | heterocyclic compound binding | 2 | 12 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_C14_Caspase3-7 | 313 | 317 | PF00656 | 0.682 |
| CLV_NRD_NRD_1 | 22 | 24 | PF00675 | 0.647 |
| CLV_NRD_NRD_1 | 271 | 273 | PF00675 | 0.249 |
| CLV_NRD_NRD_1 | 298 | 300 | PF00675 | 0.551 |
| CLV_NRD_NRD_1 | 43 | 45 | PF00675 | 0.683 |
| CLV_PCSK_KEX2_1 | 136 | 138 | PF00082 | 0.269 |
| CLV_PCSK_KEX2_1 | 298 | 300 | PF00082 | 0.324 |
| CLV_PCSK_KEX2_1 | 43 | 45 | PF00082 | 0.782 |
| CLV_PCSK_PC1ET2_1 | 136 | 138 | PF00082 | 0.269 |
| CLV_PCSK_SKI1_1 | 180 | 184 | PF00082 | 0.273 |
| CLV_PCSK_SKI1_1 | 23 | 27 | PF00082 | 0.579 |
| CLV_PCSK_SKI1_1 | 267 | 271 | PF00082 | 0.249 |
| CLV_PCSK_SKI1_1 | 30 | 34 | PF00082 | 0.610 |
| CLV_PCSK_SKI1_1 | 327 | 331 | PF00082 | 0.282 |
| DEG_APCC_DBOX_1 | 326 | 334 | PF00400 | 0.439 |
| DEG_SPOP_SBC_1 | 309 | 313 | PF00917 | 0.596 |
| DOC_CKS1_1 | 139 | 144 | PF01111 | 0.473 |
| DOC_CKS1_1 | 182 | 187 | PF01111 | 0.554 |
| DOC_CYCLIN_RxL_1 | 324 | 332 | PF00134 | 0.434 |
| DOC_CYCLIN_yCln2_LP_2 | 79 | 85 | PF00134 | 0.449 |
| DOC_MAPK_DCC_7 | 251 | 259 | PF00069 | 0.464 |
| DOC_MAPK_gen_1 | 3 | 12 | PF00069 | 0.572 |
| DOC_MAPK_MEF2A_6 | 251 | 259 | PF00069 | 0.449 |
| DOC_MAPK_MEF2A_6 | 95 | 103 | PF00069 | 0.449 |
| DOC_MAPK_RevD_3 | 285 | 299 | PF00069 | 0.571 |
| DOC_PP1_RVXF_1 | 118 | 125 | PF00149 | 0.449 |
| DOC_PP1_RVXF_1 | 21 | 28 | PF00149 | 0.566 |
| DOC_PP4_FxxP_1 | 235 | 238 | PF00568 | 0.449 |
| DOC_USP7_MATH_1 | 142 | 146 | PF00917 | 0.489 |
| DOC_USP7_MATH_1 | 172 | 176 | PF00917 | 0.449 |
| DOC_USP7_MATH_1 | 222 | 226 | PF00917 | 0.460 |
| DOC_USP7_MATH_1 | 305 | 309 | PF00917 | 0.624 |
| DOC_USP7_MATH_1 | 310 | 314 | PF00917 | 0.636 |
| DOC_USP7_MATH_1 | 61 | 65 | PF00917 | 0.471 |
| DOC_USP7_UBL2_3 | 26 | 30 | PF12436 | 0.635 |
| DOC_USP7_UBL2_3 | 91 | 95 | PF12436 | 0.449 |
| DOC_WW_Pin1_4 | 138 | 143 | PF00397 | 0.449 |
| DOC_WW_Pin1_4 | 181 | 186 | PF00397 | 0.554 |
| DOC_WW_Pin1_4 | 316 | 321 | PF00397 | 0.522 |
| DOC_WW_Pin1_4 | 35 | 40 | PF00397 | 0.715 |
| LIG_14-3-3_CanoR_1 | 213 | 217 | PF00244 | 0.447 |
| LIG_14-3-3_CanoR_1 | 223 | 230 | PF00244 | 0.449 |
| LIG_14-3-3_CanoR_1 | 232 | 236 | PF00244 | 0.449 |
| LIG_BRCT_BRCA1_1 | 277 | 281 | PF00533 | 0.449 |
| LIG_FHA_1 | 105 | 111 | PF00498 | 0.439 |
| LIG_FHA_1 | 27 | 33 | PF00498 | 0.669 |
| LIG_FHA_1 | 95 | 101 | PF00498 | 0.439 |
| LIG_LIR_Apic_2 | 234 | 238 | PF02991 | 0.449 |
| LIG_LIR_Gen_1 | 208 | 216 | PF02991 | 0.444 |
| LIG_LIR_Nem_3 | 156 | 162 | PF02991 | 0.449 |
| LIG_LIR_Nem_3 | 208 | 214 | PF02991 | 0.444 |
| LIG_LIR_Nem_3 | 260 | 265 | PF02991 | 0.449 |
| LIG_LIR_Nem_3 | 292 | 297 | PF02991 | 0.383 |
| LIG_LIR_Nem_3 | 324 | 329 | PF02991 | 0.397 |
| LIG_Pex14_2 | 194 | 198 | PF04695 | 0.449 |
| LIG_Pex14_2 | 70 | 74 | PF04695 | 0.460 |
| LIG_PTB_Apo_2 | 165 | 172 | PF02174 | 0.449 |
| LIG_PTB_Apo_2 | 68 | 75 | PF02174 | 0.317 |
| LIG_PTB_Phospho_1 | 165 | 171 | PF10480 | 0.449 |
| LIG_Rb_pABgroove_1 | 285 | 293 | PF01858 | 0.532 |
| LIG_SH2_CRK | 211 | 215 | PF00017 | 0.449 |
| LIG_SH2_SRC | 171 | 174 | PF00017 | 0.449 |
| LIG_SH2_STAP1 | 291 | 295 | PF00017 | 0.441 |
| LIG_SH2_STAT5 | 161 | 164 | PF00017 | 0.438 |
| LIG_SH2_STAT5 | 211 | 214 | PF00017 | 0.449 |
| LIG_SH2_STAT5 | 294 | 297 | PF00017 | 0.384 |
| LIG_SH3_1 | 247 | 253 | PF00018 | 0.449 |
| LIG_SH3_3 | 247 | 253 | PF00018 | 0.449 |
| LIG_UBA3_1 | 351 | 360 | PF00899 | 0.420 |
| MOD_CDK_SPxxK_3 | 181 | 188 | PF00069 | 0.554 |
| MOD_CK1_1 | 215 | 221 | PF00069 | 0.457 |
| MOD_CK1_1 | 231 | 237 | PF00069 | 0.417 |
| MOD_CK1_1 | 308 | 314 | PF00069 | 0.602 |
| MOD_GlcNHglycan | 174 | 177 | PF01048 | 0.249 |
| MOD_GlcNHglycan | 301 | 304 | PF01048 | 0.512 |
| MOD_GlcNHglycan | 307 | 310 | PF01048 | 0.711 |
| MOD_GlcNHglycan | 65 | 68 | PF01048 | 0.506 |
| MOD_GlcNHglycan | 90 | 94 | PF01048 | 0.286 |
| MOD_GSK3_1 | 104 | 111 | PF00069 | 0.448 |
| MOD_GSK3_1 | 138 | 145 | PF00069 | 0.466 |
| MOD_GSK3_1 | 26 | 33 | PF00069 | 0.599 |
| MOD_GSK3_1 | 276 | 283 | PF00069 | 0.449 |
| MOD_GSK3_1 | 305 | 312 | PF00069 | 0.568 |
| MOD_GSK3_1 | 315 | 322 | PF00069 | 0.572 |
| MOD_N-GLC_1 | 108 | 113 | PF02516 | 0.243 |
| MOD_NEK2_1 | 114 | 119 | PF00069 | 0.475 |
| MOD_NEK2_1 | 228 | 233 | PF00069 | 0.449 |
| MOD_NEK2_1 | 329 | 334 | PF00069 | 0.278 |
| MOD_NEK2_1 | 338 | 343 | PF00069 | 0.377 |
| MOD_NEK2_1 | 34 | 39 | PF00069 | 0.638 |
| MOD_PIKK_1 | 215 | 221 | PF00454 | 0.460 |
| MOD_PIKK_1 | 61 | 67 | PF00454 | 0.578 |
| MOD_PK_1 | 276 | 282 | PF00069 | 0.449 |
| MOD_PKA_1 | 275 | 281 | PF00069 | 0.449 |
| MOD_PKA_2 | 212 | 218 | PF00069 | 0.449 |
| MOD_PKA_2 | 222 | 228 | PF00069 | 0.449 |
| MOD_PKA_2 | 231 | 237 | PF00069 | 0.449 |
| MOD_Plk_1 | 241 | 247 | PF00069 | 0.449 |
| MOD_Plk_1 | 89 | 95 | PF00069 | 0.427 |
| MOD_Plk_4 | 241 | 247 | PF00069 | 0.449 |
| MOD_Plk_4 | 276 | 282 | PF00069 | 0.449 |
| MOD_Plk_4 | 310 | 316 | PF00069 | 0.450 |
| MOD_Plk_4 | 329 | 335 | PF00069 | 0.323 |
| MOD_Plk_4 | 350 | 356 | PF00069 | 0.440 |
| MOD_ProDKin_1 | 138 | 144 | PF00069 | 0.449 |
| MOD_ProDKin_1 | 181 | 187 | PF00069 | 0.554 |
| MOD_ProDKin_1 | 316 | 322 | PF00069 | 0.510 |
| MOD_ProDKin_1 | 35 | 41 | PF00069 | 0.716 |
| MOD_SUMO_for_1 | 239 | 242 | PF00179 | 0.449 |
| MOD_SUMO_rev_2 | 243 | 253 | PF00179 | 0.449 |
| TRG_DiLeu_BaEn_1 | 261 | 266 | PF01217 | 0.449 |
| TRG_ENDOCYTIC_2 | 211 | 214 | PF00928 | 0.441 |
| TRG_ENDOCYTIC_2 | 297 | 300 | PF00928 | 0.425 |
| TRG_ER_diArg_1 | 297 | 299 | PF00400 | 0.305 |
| TRG_ER_diArg_1 | 342 | 345 | PF00400 | 0.401 |
| TRG_NLS_MonoExtC_3 | 271 | 276 | PF00514 | 0.449 |
| TRG_Pf-PMV_PEXEL_1 | 327 | 331 | PF00026 | 0.389 |
| TRG_Pf-PMV_PEXEL_1 | 344 | 348 | PF00026 | 0.329 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N1IB33 | Leptomonas seymouri | 86% | 98% |
| A0A0S4JJ91 | Bodo saltans | 69% | 100% |
| A0A1X0P2H9 | Trypanosomatidae | 73% | 100% |
| A0A3S7X2X5 | Leishmania donovani | 88% | 98% |
| A0A422N140 | Trypanosoma rangeli | 72% | 100% |
| A1VUN7 | Polaromonas naphthalenivorans (strain CJ2) | 29% | 100% |
| A1WS95 | Verminephrobacter eiseniae (strain EF01-2) | 29% | 100% |
| A2C1Z5 | Prochlorococcus marinus (strain NATL1A) | 35% | 100% |
| A3CQN5 | Streptococcus sanguinis (strain SK36) | 31% | 100% |
| A4I515 | Leishmania infantum | 89% | 98% |
| A4TQD8 | Yersinia pestis (strain Pestoides F) | 30% | 100% |
| A7FMC1 | Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) | 31% | 100% |
| A8AUQ4 | Streptococcus gordonii (strain Challis / ATCC 35105 / BCRC 15272 / CH1 / DL1 / V288) | 32% | 100% |
| A9QZZ0 | Yersinia pestis bv. Antiqua (strain Angola) | 30% | 100% |
| B1AJP2 | Ureaplasma parvum serovar 3 (strain ATCC 27815 / 27 / NCTC 11736) | 30% | 100% |
| B1HS82 | Lysinibacillus sphaericus (strain C3-41) | 30% | 100% |
| B1I8T7 | Streptococcus pneumoniae (strain Hungary19A-6) | 31% | 100% |
| B1JKY3 | Yersinia pseudotuberculosis serotype O:3 (strain YPIII) | 31% | 100% |
| B2AH89 | Cupriavidus taiwanensis (strain DSM 17343 / BCRC 17206 / CCUG 44338 / CIP 107171 / LMG 19424 / R1) | 32% | 100% |
| B2JCX3 | Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 / STM815) | 34% | 100% |
| B2K487 | Yersinia pseudotuberculosis serotype IB (strain PB1/+) | 31% | 100% |
| B5E2H6 | Streptococcus pneumoniae serotype 19F (strain G54) | 31% | 100% |
| B5ZCB6 | Ureaplasma urealyticum serovar 10 (strain ATCC 33699 / Western) | 29% | 100% |
| B9DLD0 | Staphylococcus carnosus (strain TM300) | 30% | 100% |
| C1CMT3 | Streptococcus pneumoniae (strain P1031) | 31% | 100% |
| C9ZQH0 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 71% | 96% |
| E9B0E5 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 89% | 98% |
| G0SEH7 | Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) | 49% | 95% |
| O22268 | Arabidopsis thaliana | 45% | 100% |
| P41819 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 45% | 100% |
| P78697 | Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) | 47% | 100% |
| Q09522 | Caenorhabditis elegans | 46% | 100% |
| Q0KEA7 | Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) | 31% | 100% |
| Q1C0H5 | Yersinia pestis bv. Antiqua (strain Antiqua) | 30% | 100% |
| Q1CMT2 | Yersinia pestis bv. Antiqua (strain Nepal516) | 30% | 100% |
| Q1WV73 | Ligilactobacillus salivarius (strain UCC118) | 33% | 100% |
| Q2KHT8 | Bos taurus | 54% | 100% |
| Q2W0V3 | Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) | 32% | 100% |
| Q38V22 | Latilactobacillus sakei subsp. sakei (strain 23K) | 30% | 100% |
| Q3B3D4 | Chlorobium luteolum (strain DSM 273 / BCRC 81028 / 2530) | 27% | 100% |
| Q46L58 | Prochlorococcus marinus (strain NATL2A) | 34% | 100% |
| Q475Q1 | Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) | 34% | 100% |
| Q47VJ8 | Colwellia psychrerythraea (strain 34H / ATCC BAA-681) | 30% | 100% |
| Q4L3F0 | Staphylococcus haemolyticus (strain JCSC1435) | 32% | 100% |
| Q4Q7U7 | Leishmania major | 89% | 100% |
| Q54QK7 | Dictyostelium discoideum | 51% | 100% |
| Q5QVN7 | Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR) | 34% | 100% |
| Q66EQ8 | Yersinia pseudotuberculosis serotype I (strain IP32953) | 31% | 100% |
| Q6BSY5 | Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) | 46% | 100% |
| Q6C7H6 | Yarrowia lipolytica (strain CLIB 122 / E 150) | 47% | 100% |
| Q6FKY3 | Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) | 45% | 100% |
| Q6ME80 | Protochlamydia amoebophila (strain UWE25) | 30% | 100% |
| Q75C90 | Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) | 45% | 100% |
| Q88Z93 | Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1) | 32% | 100% |
| Q8TQU8 | Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) | 38% | 100% |
| Q8ZIK5 | Yersinia pestis | 30% | 100% |
| Q95KJ0 | Macaca fascicularis | 53% | 100% |
| Q9CHN8 | Lactococcus lactis subsp. lactis (strain IL1403) | 29% | 100% |
| Q9D0D4 | Mus musculus | 54% | 100% |
| Q9KGK4 | Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) | 33% | 100% |
| Q9PPN8 | Ureaplasma parvum serovar 3 (strain ATCC 700970) | 30% | 100% |
| Q9UNQ2 | Homo sapiens | 54% | 100% |
| Q9USU2 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 47% | 100% |
| Q9VAQ5 | Drosophila melanogaster | 52% | 100% |
| V5BCC0 | Trypanosoma cruzi | 72% | 100% |