Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HHW4_LEIBR

TriTrypDb:

LbrM.30.0210 , LBRM2903_300007700

Length:

119


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	10
GO:0110165	cellular anatomical entity	1	10

A4HHW4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HHW4


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	117	119	PF00675	0.455
CLV_NRD_NRD_1	32	34	PF00675	0.451
CLV_PCSK_KEX2_1	32	34	PF00082	0.435
CLV_PCSK_SKI1_1	32	36	PF00082	0.438
DEG_APCC_DBOX_1	6	14	PF00400	0.560
DEG_Nend_Nbox_1	1	3	PF02207	0.652
DEG_SPOP_SBC_1	15	19	PF00917	0.648
DOC_CKS1_1	59	64	PF01111	0.517
DOC_CYCLIN_yCln2_LP_2	59	65	PF00134	0.628
DOC_MAPK_gen_1	32	40	PF00069	0.661
DOC_USP7_MATH_1	75	79	PF00917	0.411
DOC_WW_Pin1_4	58	63	PF00397	0.513
LIG_14-3-3_CanoR_1	16	22	PF00244	0.668
LIG_14-3-3_CanoR_1	32	40	PF00244	0.569
LIG_14-3-3_CanoR_1	7	11	PF00244	0.658
LIG_BRCT_BRCA1_1	30	34	PF00533	0.696
LIG_BRCT_BRCA1_1	43	47	PF00533	0.447
LIG_FHA_1	33	39	PF00498	0.616
LIG_FHA_1	50	56	PF00498	0.312
LIG_LIR_Gen_1	53	63	PF02991	0.474
LIG_LIR_Nem_3	53	59	PF02991	0.456
LIG_LIR_Nem_3	92	97	PF02991	0.335
LIG_NRBOX	54	60	PF00104	0.447
LIG_SH3_3	19	25	PF00018	0.710
LIG_SH3_3	59	65	PF00018	0.600
LIG_SUMO_SIM_par_1	11	19	PF11976	0.617
MOD_CK1_1	18	24	PF00069	0.597
MOD_CK1_1	42	48	PF00069	0.417
MOD_CK1_1	50	56	PF00069	0.360
MOD_CK1_1	6	12	PF00069	0.648
MOD_CK2_1	109	115	PF00069	0.532
MOD_GlcNHglycan	18	21	PF01048	0.511
MOD_GlcNHglycan	77	80	PF01048	0.595
MOD_GSK3_1	11	18	PF00069	0.633
MOD_GSK3_1	28	35	PF00069	0.663
MOD_GSK3_1	41	48	PF00069	0.258
MOD_GSK3_1	71	78	PF00069	0.413
MOD_GSK3_1	85	92	PF00069	0.467
MOD_N-GLC_1	89	94	PF02516	0.586
MOD_NEK2_1	28	33	PF00069	0.654
MOD_NEK2_1	39	44	PF00069	0.376
MOD_NEK2_1	47	52	PF00069	0.281
MOD_NEK2_1	89	94	PF00069	0.395
MOD_OFUCOSY	43	49	PF10250	0.447
MOD_PIKK_1	109	115	PF00454	0.643
MOD_PKA_1	32	38	PF00069	0.664
MOD_PKA_2	15	21	PF00069	0.681
MOD_PKA_2	32	38	PF00069	0.607
MOD_PKA_2	6	12	PF00069	0.652
MOD_Plk_4	42	48	PF00069	0.376
MOD_ProDKin_1	58	64	PF00069	0.512
TRG_ER_diArg_1	32	34	PF00400	0.670


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IMG4	Leptomonas seymouri	70%	100%
A0A0S4JM96	Bodo saltans	59%	100%
A0A1X0P2D6	Trypanosomatidae	61%	100%
A0A3S7X310	Leishmania donovani	91%	100%
A0A422N153	Trypanosoma rangeli	64%	100%
A4I514	Leishmania infantum	91%	100%
C9ZQG9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	57%	100%
E9B0E4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
Q4Q7V0	Leishmania major	88%	100%