Leucine-rich repeat domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania braziliensis

UniProt:

A4HHU2_LEIBR

TriTrypDb:

LbrM.29.2910 , LBRM2903_340005400

Length:

277

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0005929	cilium	4	2
GO:0042995	cell projection	2	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0110165	cellular anatomical entity	1	2
GO:0120025	plasma membrane bounded cell projection	3	2

Expansion

Sequence features

A4HHU2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HHU2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	256	260	PF00656	0.847
CLV_C14_Caspase3-7	88	92	PF00656	0.641
CLV_NRD_NRD_1	176	178	PF00675	0.865
CLV_NRD_NRD_1	226	228	PF00675	0.879
CLV_PCSK_KEX2_1	176	178	PF00082	0.865
CLV_PCSK_KEX2_1	226	228	PF00082	0.879
CLV_PCSK_PC7_1	172	178	PF00082	0.856
CLV_Separin_Metazoa	184	188	PF03568	0.852
DEG_ODPH_VHL_1	68	79	PF01847	0.617
DOC_CDC14_PxL_1	138	146	PF14671	0.475
DOC_MAPK_MEF2A_6	52	59	PF00069	0.603
DOC_PP2B_PxIxI_1	157	163	PF00149	0.758
DOC_WW_Pin1_4	154	159	PF00397	0.720
LIG_14-3-3_CanoR_1	103	110	PF00244	0.633
LIG_14-3-3_CanoR_1	121	126	PF00244	0.320
LIG_14-3-3_CanoR_1	163	167	PF00244	0.788
LIG_14-3-3_CanoR_1	176	180	PF00244	0.630
LIG_14-3-3_CanoR_1	208	213	PF00244	0.846
LIG_14-3-3_CanoR_1	249	254	PF00244	0.848
LIG_14-3-3_CanoR_1	78	83	PF00244	0.601
LIG_BRCT_BRCA1_1	145	149	PF00533	0.623
LIG_BRCT_BRCA1_1	33	37	PF00533	0.602
LIG_FHA_1	126	132	PF00498	0.443
LIG_FHA_2	103	109	PF00498	0.637
LIG_FHA_2	254	260	PF00498	0.849
LIG_LIR_Nem_3	140	144	PF02991	0.473
LIG_LYPXL_yS_3	141	144	PF13949	0.466
LIG_SH3_3	161	167	PF00018	0.721
LIG_SH3_3	222	228	PF00018	0.869
LIG_SUMO_SIM_par_1	53	58	PF11976	0.594
MOD_CK1_1	178	184	PF00069	0.848
MOD_CK1_1	22	28	PF00069	0.672
MOD_CK1_1	252	258	PF00069	0.852
MOD_CK1_1	260	266	PF00069	0.694
MOD_CK1_1	81	87	PF00069	0.593
MOD_CK2_1	102	108	PF00069	0.275
MOD_CK2_1	178	184	PF00069	0.848
MOD_CK2_1	207	213	PF00069	0.847
MOD_CK2_1	82	88	PF00069	0.598
MOD_GlcNHglycan	125	128	PF01048	0.554
MOD_GlcNHglycan	180	183	PF01048	0.846
MOD_GSK3_1	121	128	PF00069	0.630
MOD_GSK3_1	143	150	PF00069	0.631
MOD_GSK3_1	207	214	PF00069	0.847
MOD_GSK3_1	245	252	PF00069	0.837
MOD_GSK3_1	253	260	PF00069	0.711
MOD_GSK3_1	78	85	PF00069	0.597
MOD_NEK2_1	125	130	PF00069	0.618
MOD_NEK2_2	19	24	PF00069	0.685
MOD_PIKK_1	125	131	PF00454	0.619
MOD_PIKK_1	257	263	PF00454	0.842
MOD_PK_1	78	84	PF00069	0.600
MOD_PKA_2	102	108	PF00069	0.625
MOD_PKA_2	162	168	PF00069	0.784
MOD_PKA_2	175	181	PF00069	0.626
MOD_PKA_2	207	213	PF00069	0.847
MOD_PKA_2	9	15	PF00069	0.595
MOD_PKB_1	262	270	PF00069	0.829
MOD_Plk_1	147	153	PF00069	0.648
MOD_Plk_1	19	25	PF00069	0.640
MOD_Plk_1	55	61	PF00069	0.597
MOD_Plk_2-3	175	181	PF00069	0.854
MOD_Plk_2-3	86	92	PF00069	0.511
MOD_Plk_4	33	39	PF00069	0.606
MOD_Plk_4	55	61	PF00069	0.597
MOD_ProDKin_1	154	160	PF00069	0.725
TRG_DiLeu_BaEn_2	32	38	PF01217	0.601
TRG_ENDOCYTIC_2	141	144	PF00928	0.466
TRG_ER_diArg_1	225	227	PF00400	0.866
TRG_ER_diArg_1	262	265	PF00400	0.836
TRG_NES_CRM1_1	154	169	PF08389	0.703
TRG_Pf-PMV_PEXEL_1	52	56	PF00026	0.617