Putative helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Putative helicase

Gene product:

helicase, putative

Species:

Leishmania braziliensis

UniProt:

A4HHR4_LEIBR

TriTrypDb:

LbrM.29.2630 , LBRM2903_290033500

Length:

954

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	11
GO:0043226	organelle	2	11
GO:0043227	membrane-bounded organelle	3	11
GO:0043229	intracellular organelle	3	11
GO:0043231	intracellular membrane-bounded organelle	4	11
GO:0110165	cellular anatomical entity	1	11

Expansion

Sequence features

A4HHR4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HHR4

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	12
GO:0006725	cellular aromatic compound metabolic process	3	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0008152	metabolic process	1	12
GO:0009987	cellular process	1	12
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0046483	heterocycle metabolic process	3	12
GO:0071704	organic substance metabolic process	2	12
GO:1901360	organic cyclic compound metabolic process	3	12
GO:0000018	regulation of DNA recombination	6	1
GO:0000723	telomere maintenance	5	1
GO:0006259	DNA metabolic process	4	1
GO:0006282	regulation of DNA repair	6	1
GO:0006996	organelle organization	4	1
GO:0009892	negative regulation of metabolic process	4	1
GO:0010569	regulation of double-strand break repair via homologous recombination	7	1
GO:0010605	negative regulation of macromolecule metabolic process	5	1
GO:0016043	cellular component organization	3	1
GO:0019219	regulation of nucleobase-containing compound metabolic process	5	1
GO:0019222	regulation of metabolic process	3	1
GO:0031323	regulation of cellular metabolic process	4	1
GO:0031324	negative regulation of cellular metabolic process	5	1
GO:0032200	telomere organization	6	1
GO:0032204	regulation of telomere maintenance	6	1
GO:0032392	DNA geometric change	7	1
GO:0032508	DNA duplex unwinding	8	1
GO:0033043	regulation of organelle organization	5	1
GO:0033044	regulation of chromosome organization	6	1
GO:0043170	macromolecule metabolic process	3	1
GO:0044087	regulation of cellular component biogenesis	4	1
GO:0044260	obsolete cellular macromolecule metabolic process	3	1
GO:0045910	negative regulation of DNA recombination	7	1
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	6	1
GO:0048519	negative regulation of biological process	3	1
GO:0048523	negative regulation of cellular process	4	1
GO:0048583	regulation of response to stimulus	3	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0051052	regulation of DNA metabolic process	5	1
GO:0051053	negative regulation of DNA metabolic process	6	1
GO:0051128	regulation of cellular component organization	4	1
GO:0051129	negative regulation of cellular component organization	5	1
GO:0051171	regulation of nitrogen compound metabolic process	4	1
GO:0051172	negative regulation of nitrogen compound metabolic process	5	1
GO:0051276	chromosome organization	5	1
GO:0060255	regulation of macromolecule metabolic process	4	1
GO:0065007	biological regulation	1	1
GO:0071103	DNA conformation change	6	1
GO:0071840	cellular component organization or biogenesis	2	1
GO:0080090	regulation of primary metabolic process	4	1
GO:0080134	regulation of response to stress	4	1
GO:0080135	regulation of cellular response to stress	4	1
GO:0090304	nucleic acid metabolic process	4	1
GO:0090657	telomeric loop disassembly	6	1
GO:1904429	regulation of t-circle formation	5	1
GO:1904430	negative regulation of t-circle formation	6	1
GO:2000779	regulation of double-strand break repair	7	1
GO:2001020	obsolete regulation of response to DNA damage stimulus	5	1
GO:0006950	response to stress	2	3
GO:0006974	DNA damage response	4	3
GO:0033554	cellular response to stress	3	3
GO:0050896	response to stimulus	1	3
GO:0051716	cellular response to stimulus	2	3

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003677	DNA binding	4	12
GO:0003678	DNA helicase activity	3	12
GO:0003824	catalytic activity	1	12
GO:0004386	helicase activity	2	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0008094	ATP-dependent activity, acting on DNA	2	12
GO:0016787	hydrolase activity	2	12
GO:0016817	hydrolase activity, acting on acid anhydrides	3	12
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	12
GO:0017076	purine nucleotide binding	4	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140097	catalytic activity, acting on DNA	3	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12
GO:0005515	protein binding	2	1
GO:0019899	enzyme binding	3	1
GO:0070182	DNA polymerase binding	4	1
GO:0016462	pyrophosphatase activity	5	1
GO:0016887	ATP hydrolysis activity	7	1
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	603	607	PF00656	0.513
CLV_C14_Caspase3-7	64	68	PF00656	0.355
CLV_C14_Caspase3-7	727	731	PF00656	0.452
CLV_MEL_PAP_1	498	504	PF00089	0.437
CLV_NRD_NRD_1	106	108	PF00675	0.177
CLV_NRD_NRD_1	700	702	PF00675	0.528
CLV_NRD_NRD_1	722	724	PF00675	0.499
CLV_NRD_NRD_1	775	777	PF00675	0.543
CLV_PCSK_FUR_1	628	632	PF00082	0.253
CLV_PCSK_FUR_1	773	777	PF00082	0.636
CLV_PCSK_KEX2_1	106	108	PF00082	0.264
CLV_PCSK_KEX2_1	630	632	PF00082	0.253
CLV_PCSK_KEX2_1	699	701	PF00082	0.535
CLV_PCSK_KEX2_1	722	724	PF00082	0.476
CLV_PCSK_KEX2_1	773	775	PF00082	0.554
CLV_PCSK_PC1ET2_1	630	632	PF00082	0.253
CLV_PCSK_SKI1_1	129	133	PF00082	0.364
CLV_PCSK_SKI1_1	295	299	PF00082	0.344
CLV_PCSK_SKI1_1	342	346	PF00082	0.421
CLV_PCSK_SKI1_1	364	368	PF00082	0.465
CLV_PCSK_SKI1_1	374	378	PF00082	0.433
CLV_PCSK_SKI1_1	401	405	PF00082	0.379
CLV_PCSK_SKI1_1	557	561	PF00082	0.243
CLV_PCSK_SKI1_1	610	614	PF00082	0.339
CLV_PCSK_SKI1_1	647	651	PF00082	0.253
CLV_PCSK_SKI1_1	781	785	PF00082	0.648
CLV_PCSK_SKI1_1	882	886	PF00082	0.459
CLV_PCSK_SKI1_1	892	896	PF00082	0.488
CLV_PCSK_SKI1_1	914	918	PF00082	0.474
CLV_PCSK_SKI1_1	926	930	PF00082	0.406
DEG_SPOP_SBC_1	242	246	PF00917	0.558
DOC_CYCLIN_RxL_1	217	225	PF00134	0.464
DOC_CYCLIN_RxL_1	412	423	PF00134	0.477
DOC_CYCLIN_RxL_1	46	57	PF00134	0.367
DOC_CYCLIN_RxL_1	923	931	PF00134	0.301
DOC_CYCLIN_yCln2_LP_2	168	171	PF00134	0.474
DOC_CYCLIN_yCln2_LP_2	798	804	PF00134	0.465
DOC_MAPK_gen_1	426	435	PF00069	0.406
DOC_MAPK_gen_1	595	604	PF00069	0.466
DOC_MAPK_gen_1	628	636	PF00069	0.474
DOC_MAPK_gen_1	672	681	PF00069	0.513
DOC_MAPK_MEF2A_6	426	435	PF00069	0.406
DOC_MAPK_MEF2A_6	586	593	PF00069	0.477
DOC_MAPK_MEF2A_6	870	877	PF00069	0.344
DOC_MAPK_NFAT4_5	586	594	PF00069	0.477
DOC_PP1_RVXF_1	413	420	PF00149	0.472
DOC_PP1_RVXF_1	924	930	PF00149	0.425
DOC_PP2B_LxvP_1	168	171	PF13499	0.474
DOC_PP2B_LxvP_1	636	639	PF13499	0.474
DOC_PP2B_LxvP_1	798	801	PF13499	0.463
DOC_PP2B_LxvP_1	909	912	PF13499	0.514
DOC_PP4_FxxP_1	560	563	PF00568	0.453
DOC_USP7_MATH_1	375	379	PF00917	0.505
DOC_USP7_MATH_1	434	438	PF00917	0.473
DOC_USP7_MATH_1	528	532	PF00917	0.497
DOC_USP7_MATH_1	563	567	PF00917	0.533
DOC_USP7_MATH_1	62	66	PF00917	0.446
DOC_USP7_MATH_1	783	787	PF00917	0.644
DOC_USP7_MATH_1	805	809	PF00917	0.715
DOC_USP7_MATH_1	912	916	PF00917	0.526
DOC_WW_Pin1_4	249	254	PF00397	0.504
DOC_WW_Pin1_4	315	320	PF00397	0.629
DOC_WW_Pin1_4	40	45	PF00397	0.367
DOC_WW_Pin1_4	443	448	PF00397	0.342
DOC_WW_Pin1_4	512	517	PF00397	0.464
DOC_WW_Pin1_4	580	585	PF00397	0.539
DOC_WW_Pin1_4	791	796	PF00397	0.632
DOC_WW_Pin1_4	852	857	PF00397	0.609
DOC_WW_Pin1_4	895	900	PF00397	0.515
LIG_14-3-3_CanoR_1	106	111	PF00244	0.539
LIG_14-3-3_CanoR_1	113	117	PF00244	0.538
LIG_14-3-3_CanoR_1	133	143	PF00244	0.558
LIG_14-3-3_CanoR_1	271	279	PF00244	0.606
LIG_14-3-3_CanoR_1	374	380	PF00244	0.516
LIG_14-3-3_CanoR_1	495	499	PF00244	0.435
LIG_14-3-3_CanoR_1	595	604	PF00244	0.448
LIG_14-3-3_CanoR_1	703	712	PF00244	0.464
LIG_14-3-3_CanoR_1	723	733	PF00244	0.358
LIG_14-3-3_CanoR_1	81	90	PF00244	0.487
LIG_14-3-3_CanoR_1	850	856	PF00244	0.575
LIG_14-3-3_CanoR_1	926	936	PF00244	0.289
LIG_Actin_WH2_2	448	466	PF00022	0.269
LIG_Actin_WH2_2	573	588	PF00022	0.558
LIG_APCC_ABBA_1	303	308	PF00400	0.504
LIG_APCC_ABBAyCdc20_2	701	707	PF00400	0.395
LIG_BIR_III_2	730	734	PF00653	0.467
LIG_BRCT_BRCA1_1	12	16	PF00533	0.385
LIG_BRCT_BRCA1_1	328	332	PF00533	0.470
LIG_BRCT_BRCA1_1	398	402	PF00533	0.470
LIG_BRCT_BRCA1_1	861	865	PF00533	0.441
LIG_EH1_1	175	183	PF00400	0.453
LIG_eIF4E_1	212	218	PF01652	0.377
LIG_FHA_1	113	119	PF00498	0.450
LIG_FHA_1	255	261	PF00498	0.411
LIG_FHA_1	339	345	PF00498	0.400
LIG_FHA_1	398	404	PF00498	0.471
LIG_FHA_1	48	54	PF00498	0.368
LIG_FHA_1	544	550	PF00498	0.493
LIG_FHA_1	580	586	PF00498	0.535
LIG_FHA_1	727	733	PF00498	0.689
LIG_FHA_1	83	89	PF00498	0.436
LIG_FHA_1	97	103	PF00498	0.492
LIG_FHA_2	62	68	PF00498	0.325
LIG_FHA_2	648	654	PF00498	0.453
LIG_FHA_2	725	731	PF00498	0.588
LIG_FHA_2	741	747	PF00498	0.506
LIG_FHA_2	821	827	PF00498	0.718
LIG_FHA_2	833	839	PF00498	0.718
LIG_FHA_2	859	865	PF00498	0.462
LIG_LIR_Gen_1	329	340	PF02991	0.474
LIG_LIR_Gen_1	384	392	PF02991	0.430
LIG_LIR_Gen_1	525	533	PF02991	0.453
LIG_LIR_Gen_1	623	634	PF02991	0.453
LIG_LIR_Gen_1	702	713	PF02991	0.440
LIG_LIR_Gen_1	862	873	PF02991	0.416
LIG_LIR_Gen_1	876	886	PF02991	0.396
LIG_LIR_Gen_1	921	932	PF02991	0.475
LIG_LIR_Nem_3	13	19	PF02991	0.394
LIG_LIR_Nem_3	188	193	PF02991	0.482
LIG_LIR_Nem_3	204	210	PF02991	0.401
LIG_LIR_Nem_3	329	335	PF02991	0.450
LIG_LIR_Nem_3	384	388	PF02991	0.406
LIG_LIR_Nem_3	416	422	PF02991	0.334
LIG_LIR_Nem_3	548	553	PF02991	0.461
LIG_LIR_Nem_3	623	629	PF02991	0.453
LIG_LIR_Nem_3	632	636	PF02991	0.451
LIG_LIR_Nem_3	675	680	PF02991	0.445
LIG_LIR_Nem_3	684	690	PF02991	0.440
LIG_LIR_Nem_3	702	708	PF02991	0.257
LIG_LIR_Nem_3	862	868	PF02991	0.436
LIG_LIR_Nem_3	876	881	PF02991	0.361
LIG_LIR_Nem_3	921	927	PF02991	0.512
LIG_LIR_Nem_3	938	943	PF02991	0.369
LIG_NRBOX	293	299	PF00104	0.445
LIG_NRBOX	905	911	PF00104	0.450
LIG_PCNA_PIPBox_1	379	388	PF02747	0.493
LIG_PCNA_PIPBox_1	529	538	PF02747	0.558
LIG_PCNA_yPIPBox_3	133	147	PF02747	0.377
LIG_PCNA_yPIPBox_3	661	671	PF02747	0.453
LIG_Pex14_2	190	194	PF04695	0.513
LIG_Pex14_2	388	392	PF04695	0.247
LIG_PTB_Apo_2	324	331	PF02174	0.254
LIG_PTB_Phospho_1	324	330	PF10480	0.260
LIG_REV1ctd_RIR_1	153	161	PF16727	0.527
LIG_REV1ctd_RIR_1	716	727	PF16727	0.562
LIG_SH2_CRK	210	214	PF00017	0.464
LIG_SH2_CRK	677	681	PF00017	0.464
LIG_SH2_CRK	712	716	PF00017	0.355
LIG_SH2_CRK	924	928	PF00017	0.301
LIG_SH2_GRB2like	619	622	PF00017	0.509
LIG_SH2_NCK_1	712	716	PF00017	0.355
LIG_SH2_NCK_1	757	761	PF00017	0.634
LIG_SH2_PTP2	633	636	PF00017	0.474
LIG_SH2_PTP2	734	737	PF00017	0.691
LIG_SH2_SRC	306	309	PF00017	0.554
LIG_SH2_SRC	619	622	PF00017	0.539
LIG_SH2_SRC	757	760	PF00017	0.631
LIG_SH2_STAP1	110	114	PF00017	0.513
LIG_SH2_STAP1	712	716	PF00017	0.355
LIG_SH2_STAP1	944	948	PF00017	0.493
LIG_SH2_STAT3	19	22	PF00017	0.381
LIG_SH2_STAT5	193	196	PF00017	0.494
LIG_SH2_STAT5	212	215	PF00017	0.342
LIG_SH2_STAT5	633	636	PF00017	0.445
LIG_SH2_STAT5	734	737	PF00017	0.691
LIG_SH2_STAT5	90	93	PF00017	0.453
LIG_SH3_3	203	209	PF00018	0.453
LIG_SH3_3	428	434	PF00018	0.501
LIG_SH3_3	465	471	PF00018	0.435
LIG_SH3_3	518	524	PF00018	0.453
LIG_SH3_3	636	642	PF00018	0.477
LIG_SH3_3	789	795	PF00018	0.635
LIG_SH3_3	9	15	PF00018	0.373
LIG_SUMO_SIM_anti_2	632	638	PF11976	0.377
LIG_SUMO_SIM_par_1	229	235	PF11976	0.454
LIG_SUMO_SIM_par_1	252	258	PF11976	0.414
LIG_SUMO_SIM_par_1	678	685	PF11976	0.513
LIG_SxIP_EBH_1	610	623	PF03271	0.474
LIG_TRAF2_1	284	287	PF00917	0.497
LIG_TRAF2_1	309	312	PF00917	0.517
LIG_TRFH_1	212	216	PF08558	0.539
LIG_TYR_ITIM	208	213	PF00017	0.392
LIG_TYR_ITIM	732	737	PF00017	0.693
LIG_UBA3_1	213	220	PF00899	0.474
LIG_UBA3_1	331	337	PF00899	0.362
LIG_UBA3_1	552	557	PF00899	0.493
LIG_UBA3_1	625	630	PF00899	0.453
LIG_WRC_WIRS_1	385	390	PF05994	0.301
MOD_CDC14_SPxK_1	583	586	PF00782	0.539
MOD_CDK_SPK_2	852	857	PF00069	0.460
MOD_CDK_SPxK_1	580	586	PF00069	0.539
MOD_CK1_1	241	247	PF00069	0.508
MOD_CK1_1	351	357	PF00069	0.407
MOD_CK1_1	493	499	PF00069	0.543
MOD_CK1_1	692	698	PF00069	0.502
MOD_CK1_1	749	755	PF00069	0.639
MOD_CK1_1	786	792	PF00069	0.594
MOD_CK1_1	794	800	PF00069	0.605
MOD_CK1_1	8	14	PF00069	0.498
MOD_CK1_1	807	813	PF00069	0.651
MOD_CK1_1	824	830	PF00069	0.668
MOD_CK1_1	852	858	PF00069	0.588
MOD_CK2_1	25	31	PF00069	0.240
MOD_CK2_1	296	302	PF00069	0.418
MOD_CK2_1	528	534	PF00069	0.545
MOD_CK2_1	71	77	PF00069	0.625
MOD_CK2_1	740	746	PF00069	0.728
MOD_CK2_1	820	826	PF00069	0.718
MOD_CK2_1	832	838	PF00069	0.719
MOD_CK2_1	842	848	PF00069	0.684
MOD_CK2_1	858	864	PF00069	0.432
MOD_GlcNHglycan	160	163	PF01048	0.299
MOD_GlcNHglycan	187	190	PF01048	0.339
MOD_GlcNHglycan	353	356	PF01048	0.617
MOD_GlcNHglycan	441	444	PF01048	0.362
MOD_GlcNHglycan	483	486	PF01048	0.439
MOD_GlcNHglycan	539	542	PF01048	0.302
MOD_GlcNHglycan	691	694	PF01048	0.283
MOD_GlcNHglycan	7	10	PF01048	0.472
MOD_GlcNHglycan	73	76	PF01048	0.624
MOD_GlcNHglycan	749	752	PF01048	0.500
MOD_GlcNHglycan	785	788	PF01048	0.641
MOD_GlcNHglycan	807	810	PF01048	0.622
MOD_GlcNHglycan	815	819	PF01048	0.614
MOD_GlcNHglycan	822	826	PF01048	0.646
MOD_GlcNHglycan	844	847	PF01048	0.598
MOD_GSK3_1	129	136	PF00069	0.528
MOD_GSK3_1	142	149	PF00069	0.361
MOD_GSK3_1	238	245	PF00069	0.476
MOD_GSK3_1	346	353	PF00069	0.635
MOD_GSK3_1	40	47	PF00069	0.389
MOD_GSK3_1	434	441	PF00069	0.358
MOD_GSK3_1	490	497	PF00069	0.533
MOD_GSK3_1	512	519	PF00069	0.517
MOD_GSK3_1	699	706	PF00069	0.519
MOD_GSK3_1	800	807	PF00069	0.638
MOD_GSK3_1	820	827	PF00069	0.697
MOD_GSK3_1	828	835	PF00069	0.680
MOD_GSK3_1	947	954	PF00069	0.508
MOD_LATS_1	645	651	PF00433	0.535
MOD_N-GLC_1	326	331	PF02516	0.254
MOD_N-GLC_1	5	10	PF02516	0.474
MOD_N-GLC_1	563	568	PF02516	0.324
MOD_N-GLC_1	620	625	PF02516	0.264
MOD_N-GLC_1	852	857	PF02516	0.635
MOD_N-GLC_2	664	666	PF02516	0.264
MOD_NEK2_1	105	110	PF00069	0.474
MOD_NEK2_1	243	248	PF00069	0.502
MOD_NEK2_1	25	30	PF00069	0.453
MOD_NEK2_1	254	259	PF00069	0.352
MOD_NEK2_1	314	319	PF00069	0.560
MOD_NEK2_1	397	402	PF00069	0.432
MOD_NEK2_1	422	427	PF00069	0.357
MOD_NEK2_1	435	440	PF00069	0.339
MOD_NEK2_1	463	468	PF00069	0.304
MOD_NEK2_1	504	509	PF00069	0.413
MOD_NEK2_1	53	58	PF00069	0.358
MOD_NEK2_1	769	774	PF00069	0.605
MOD_NEK2_1	804	809	PF00069	0.683
MOD_NEK2_1	820	825	PF00069	0.578
MOD_NEK2_1	858	863	PF00069	0.398
MOD_NEK2_1	868	873	PF00069	0.322
MOD_NEK2_1	894	899	PF00069	0.592
MOD_NEK2_1	947	952	PF00069	0.566
MOD_NEK2_2	912	917	PF00069	0.524
MOD_PIKK_1	134	140	PF00454	0.522
MOD_PIKK_1	62	68	PF00454	0.558
MOD_PIKK_1	96	102	PF00454	0.470
MOD_PKA_1	106	112	PF00069	0.539
MOD_PKA_1	699	705	PF00069	0.411
MOD_PKA_2	105	111	PF00069	0.542
MOD_PKA_2	112	118	PF00069	0.534
MOD_PKA_2	270	276	PF00069	0.562
MOD_PKA_2	494	500	PF00069	0.430
MOD_PKA_2	699	705	PF00069	0.442
MOD_PKA_2	70	76	PF00069	0.672
MOD_PKA_2	724	730	PF00069	0.646
MOD_PKA_2	849	855	PF00069	0.754
MOD_PKB_1	701	709	PF00069	0.525
MOD_Plk_1	129	135	PF00069	0.558
MOD_Plk_1	397	403	PF00069	0.438
MOD_Plk_1	422	428	PF00069	0.433
MOD_Plk_1	920	926	PF00069	0.476
MOD_Plk_2-3	832	838	PF00069	0.508
MOD_Plk_4	142	148	PF00069	0.377
MOD_Plk_4	238	244	PF00069	0.495
MOD_Plk_4	326	332	PF00069	0.381
MOD_Plk_4	364	370	PF00069	0.497
MOD_Plk_4	384	390	PF00069	0.167
MOD_Plk_4	435	441	PF00069	0.403
MOD_Plk_4	516	522	PF00069	0.523
MOD_Plk_4	528	534	PF00069	0.497
MOD_Plk_4	545	551	PF00069	0.449
MOD_Plk_4	568	574	PF00069	0.487
MOD_Plk_4	794	800	PF00069	0.621
MOD_ProDKin_1	249	255	PF00069	0.499
MOD_ProDKin_1	315	321	PF00069	0.619
MOD_ProDKin_1	40	46	PF00069	0.376
MOD_ProDKin_1	443	449	PF00069	0.343
MOD_ProDKin_1	512	518	PF00069	0.464
MOD_ProDKin_1	580	586	PF00069	0.539
MOD_ProDKin_1	791	797	PF00069	0.631
MOD_ProDKin_1	852	858	PF00069	0.593
MOD_ProDKin_1	895	901	PF00069	0.514
MOD_SUMO_for_1	629	632	PF00179	0.456
MOD_SUMO_rev_2	540	549	PF00179	0.539
MOD_SUMO_rev_2	554	559	PF00179	0.479
MOD_SUMO_rev_2	778	786	PF00179	0.659
TRG_DiLeu_BaEn_1	632	637	PF01217	0.377
TRG_DiLeu_BaEn_1	905	910	PF01217	0.288
TRG_DiLeu_BaEn_2	383	389	PF01217	0.483
TRG_DiLeu_BaEn_2	863	869	PF01217	0.427
TRG_DiLeu_BaEn_4	286	292	PF01217	0.430
TRG_DiLeu_BaEn_4	938	944	PF01217	0.561
TRG_DiLeu_BaLyEn_6	213	218	PF01217	0.377
TRG_DiLeu_BaLyEn_6	890	895	PF01217	0.575
TRG_DiLeu_LyEn_5	905	910	PF01217	0.288
TRG_ENDOCYTIC_2	210	213	PF00928	0.451
TRG_ENDOCYTIC_2	526	529	PF00928	0.453
TRG_ENDOCYTIC_2	633	636	PF00928	0.474
TRG_ENDOCYTIC_2	677	680	PF00928	0.458
TRG_ENDOCYTIC_2	712	715	PF00928	0.355
TRG_ENDOCYTIC_2	734	737	PF00928	0.691
TRG_ENDOCYTIC_2	878	881	PF00928	0.387
TRG_ENDOCYTIC_2	924	927	PF00928	0.452
TRG_ENDOCYTIC_2	944	947	PF00928	0.447
TRG_ER_diArg_1	105	107	PF00400	0.413
TRG_ER_diArg_1	698	701	PF00400	0.500
TRG_ER_diArg_1	722	725	PF00400	0.490
TRG_ER_diArg_1	762	765	PF00400	0.547
TRG_ER_diArg_1	773	776	PF00400	0.553
TRG_Pf-PMV_PEXEL_1	892	896	PF00026	0.341
TRG_Pf-PMV_PEXEL_1	926	931	PF00026	0.528
TRG_Pf-PMV_PEXEL_1	934	938	PF00026	0.527
TRG_Pf-PMV_PEXEL_1	941	946	PF00026	0.534

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6K3	Leptomonas seymouri	69%	99%
A0A0N1PBH5	Leptomonas seymouri	24%	100%
A0A0P0V4R0	Oryza sativa subsp. japonica	36%	94%
A0A0S4KH73	Bodo saltans	39%	92%
A0A0S4KNN1	Bodo saltans	24%	100%
A0A1X0NWG0	Trypanosomatidae	25%	100%
A0A1X0P9Z9	Trypanosomatidae	48%	98%
A0A3R7MDU1	Trypanosoma rangeli	51%	99%
A0A3S7WYU3	Leishmania donovani	23%	100%
A0A3S7X2X3	Leishmania donovani	86%	100%
A1CJ34	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	27%	100%
A1D8E4	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	26%	100%
A2QY22	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	27%	100%
A3LN13	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	26%	100%
A4HDT9	Leishmania braziliensis	24%	100%
A4I136	Leishmania infantum	24%	100%
A4I4X4	Leishmania infantum	86%	100%
A4K436	Bos taurus	35%	78%
A6QLJ0	Bos taurus	27%	100%
A8MPP1	Homo sapiens	27%	100%
B0W9F4	Culex quinquefasciatus	32%	98%
B3MSG8	Drosophila ananassae	32%	96%
B4JNS2	Drosophila grimshawi	32%	97%
B4NDG5	Drosophila willistoni	33%	96%
B4PZB4	Drosophila yakuba	33%	97%
C9ZKX7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	48%	99%
E9AEC8	Leishmania major	86%	100%
E9ALF8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%
E9AX74	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
F1R345	Danio rerio	28%	100%
F4HQE2	Arabidopsis thaliana	36%	92%
O08811	Mus musculus	27%	100%
O14147	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	27%	100%
P06839	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	26%	100%
P0C928	Danio rerio	34%	81%
P18074	Homo sapiens	28%	100%
P26659	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	27%	100%
Q0VGM9	Mus musculus	34%	79%
Q16X92	Aedes aegypti	33%	94%
Q1E5T3	Coccidioides immitis (strain RS)	28%	100%
Q21489	Caenorhabditis elegans	25%	100%
Q2U587	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	27%	100%
Q3YK19	Gallus gallus	29%	76%
Q4QAA2	Leishmania major	24%	100%
Q55G81	Dictyostelium discoideum	26%	100%
Q5RE34	Pongo abelii	34%	73%
Q5RJZ1	Rattus norvegicus	34%	75%
Q5SXJ3	Mus musculus	30%	81%
Q60452	Cricetulus griseus	28%	100%
Q6AXC6	Mus musculus	27%	100%
Q6BZD9	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	23%	100%
Q6FKT4	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	25%	100%
Q6H1L8	Mus spretus	34%	79%
Q7QEI1	Anopheles gambiae	33%	96%
Q92771	Homo sapiens	27%	100%
Q93575	Caenorhabditis elegans	32%	96%
Q96FC9	Homo sapiens	27%	98%
Q9BX63	Homo sapiens	29%	76%
Q9NZ71	Homo sapiens	34%	78%
V5BAP9	Trypanosoma cruzi	29%	100%
V5BX91	Trypanosoma cruzi	49%	100%