RanBD1 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HHQ6_LEIBR

TriTrypDb:

LbrM.29.2550 , LBRM2903_290032600

Length:

669

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HHQ6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HHQ6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	270	274	PF00656	0.552
CLV_C14_Caspase3-7	43	47	PF00656	0.568
CLV_NRD_NRD_1	133	135	PF00675	0.724
CLV_NRD_NRD_1	243	245	PF00675	0.767
CLV_NRD_NRD_1	55	57	PF00675	0.592
CLV_PCSK_KEX2_1	133	135	PF00082	0.724
CLV_PCSK_KEX2_1	227	229	PF00082	0.772
CLV_PCSK_KEX2_1	55	57	PF00082	0.592
CLV_PCSK_KEX2_1	588	590	PF00082	0.623
CLV_PCSK_PC1ET2_1	227	229	PF00082	0.739
CLV_PCSK_PC1ET2_1	588	590	PF00082	0.623
CLV_PCSK_PC7_1	584	590	PF00082	0.584
CLV_PCSK_SKI1_1	230	234	PF00082	0.636
CLV_PCSK_SKI1_1	248	252	PF00082	0.692
CLV_PCSK_SKI1_1	391	395	PF00082	0.654
CLV_PCSK_SKI1_1	487	491	PF00082	0.597
CLV_PCSK_SKI1_1	588	592	PF00082	0.760
CLV_PCSK_SKI1_1	78	82	PF00082	0.628
DEG_APCC_DBOX_1	211	219	PF00400	0.623
DEG_SCF_FBW7_1	99	106	PF00400	0.659
DEG_SPOP_SBC_1	35	39	PF00917	0.578
DOC_CKS1_1	100	105	PF01111	0.668
DOC_MAPK_gen_1	227	233	PF00069	0.558
DOC_MAPK_RevD_3	229	245	PF00069	0.574
DOC_PP1_RVXF_1	228	234	PF00149	0.552
DOC_PP2B_LxvP_1	216	219	PF13499	0.690
DOC_PP2B_LxvP_1	276	279	PF13499	0.727
DOC_PP4_FxxP_1	182	185	PF00568	0.698
DOC_PP4_FxxP_1	194	197	PF00568	0.576
DOC_PP4_FxxP_1	645	648	PF00568	0.703
DOC_USP7_MATH_1	107	111	PF00917	0.714
DOC_USP7_MATH_1	135	139	PF00917	0.707
DOC_USP7_MATH_1	20	24	PF00917	0.800
DOC_USP7_MATH_1	201	205	PF00917	0.600
DOC_USP7_MATH_1	208	212	PF00917	0.715
DOC_USP7_MATH_1	268	272	PF00917	0.677
DOC_USP7_MATH_1	27	31	PF00917	0.686
DOC_USP7_MATH_1	279	283	PF00917	0.580
DOC_USP7_MATH_1	304	308	PF00917	0.582
DOC_USP7_MATH_1	348	352	PF00917	0.761
DOC_USP7_MATH_1	403	407	PF00917	0.591
DOC_USP7_MATH_1	44	48	PF00917	0.548
DOC_USP7_MATH_1	444	448	PF00917	0.579
DOC_USP7_MATH_1	499	503	PF00917	0.671
DOC_USP7_MATH_1	540	544	PF00917	0.580
DOC_USP7_MATH_1	568	572	PF00917	0.599
DOC_USP7_MATH_1	616	620	PF00917	0.648
DOC_USP7_UBL2_3	293	297	PF12436	0.568
DOC_WW_Pin1_4	168	173	PF00397	0.553
DOC_WW_Pin1_4	332	337	PF00397	0.622
DOC_WW_Pin1_4	407	412	PF00397	0.735
DOC_WW_Pin1_4	503	508	PF00397	0.659
DOC_WW_Pin1_4	593	598	PF00397	0.716
DOC_WW_Pin1_4	623	628	PF00397	0.573
DOC_WW_Pin1_4	85	90	PF00397	0.581
DOC_WW_Pin1_4	92	97	PF00397	0.636
DOC_WW_Pin1_4	99	104	PF00397	0.673
LIG_14-3-3_CanoR_1	134	142	PF00244	0.809
LIG_14-3-3_CanoR_1	212	216	PF00244	0.792
LIG_14-3-3_CanoR_1	55	61	PF00244	0.401
LIG_BIR_II_1	1	5	PF00653	0.653
LIG_BRCT_BRCA1_1	362	366	PF00533	0.550
LIG_BRCT_BRCA1_1	405	409	PF00533	0.566
LIG_BRCT_BRCA1_1	458	462	PF00533	0.551
LIG_BRCT_BRCA1_1	501	505	PF00533	0.559
LIG_BRCT_BRCA1_1	554	558	PF00533	0.553
LIG_BRCT_BRCA1_1	600	604	PF00533	0.705
LIG_BRCT_BRCA1_1	625	629	PF00533	0.555
LIG_BRCT_BRCA1_1	658	662	PF00533	0.733
LIG_BRCT_BRCA1_2	362	368	PF00533	0.552
LIG_BRCT_BRCA1_2	458	464	PF00533	0.551
LIG_BRCT_BRCA1_2	554	560	PF00533	0.554
LIG_EH_1	430	434	PF12763	0.705
LIG_EH_1	526	530	PF12763	0.693
LIG_EVH1_2	333	337	PF00568	0.537
LIG_EVH1_2	429	433	PF00568	0.545
LIG_EVH1_2	525	529	PF00568	0.541
LIG_FHA_1	100	106	PF00498	0.668
LIG_FHA_1	125	131	PF00498	0.737
LIG_FHA_1	251	257	PF00498	0.569
LIG_FHA_1	275	281	PF00498	0.782
LIG_FHA_2	247	253	PF00498	0.752
LIG_LIR_Apic_2	644	648	PF02991	0.602
LIG_LIR_Gen_1	139	150	PF02991	0.552
LIG_LIR_Gen_1	59	69	PF02991	0.430
LIG_LIR_Nem_3	139	145	PF02991	0.565
LIG_LIR_Nem_3	188	193	PF02991	0.754
LIG_LIR_Nem_3	406	412	PF02991	0.623
LIG_LIR_Nem_3	502	508	PF02991	0.654
LIG_LIR_Nem_3	59	65	PF02991	0.510
LIG_LIR_Nem_3	85	90	PF02991	0.594
LIG_LYPXL_S_1	189	193	PF13949	0.718
LIG_LYPXL_SIV_4	61	69	PF13949	0.608
LIG_LYPXL_yS_3	190	193	PF13949	0.720
LIG_PCNA_PIPBox_1	175	184	PF02747	0.707
LIG_PCNA_yPIPBox_3	169	182	PF02747	0.718
LIG_PTAP_UEV_1	305	310	PF05743	0.560
LIG_SH2_CRK	142	146	PF00017	0.669
LIG_SH2_CRK	62	66	PF00017	0.599
LIG_SH2_CRK	87	91	PF00017	0.579
LIG_SH2_NCK_1	62	66	PF00017	0.599
LIG_SH2_STAP1	53	57	PF00017	0.412
LIG_SH2_STAT5	181	184	PF00017	0.738
LIG_SH2_STAT5	87	90	PF00017	0.595
LIG_SH3_1	350	356	PF00018	0.763
LIG_SH3_1	446	452	PF00018	0.581
LIG_SH3_1	542	548	PF00018	0.572
LIG_SH3_3	143	149	PF00018	0.716
LIG_SH3_3	303	309	PF00018	0.746
LIG_SH3_3	330	336	PF00018	0.540
LIG_SH3_3	350	356	PF00018	0.778
LIG_SH3_3	426	432	PF00018	0.706
LIG_SH3_3	446	452	PF00018	0.706
LIG_SH3_3	522	528	PF00018	0.701
LIG_SH3_3	542	548	PF00018	0.498
LIG_SH3_3	93	99	PF00018	0.653
LIG_SUMO_SIM_par_1	214	221	PF11976	0.623
LIG_SUMO_SIM_par_1	251	259	PF11976	0.566
LIG_TRAF2_1	237	240	PF00917	0.560
LIG_TYR_ITIM	60	65	PF00017	0.666
MOD_CDK_SPxK_1	85	91	PF00069	0.559
MOD_CK1_1	106	112	PF00069	0.629
MOD_CK1_1	204	210	PF00069	0.681
MOD_CK1_1	211	217	PF00069	0.711
MOD_CK1_1	335	341	PF00069	0.543
MOD_CK1_1	607	613	PF00069	0.547
MOD_CK1_1	619	625	PF00069	0.542
MOD_CK1_1	657	663	PF00069	0.663
MOD_CK1_1	94	100	PF00069	0.598
MOD_CK2_1	348	354	PF00069	0.641
MOD_CK2_1	392	398	PF00069	0.588
MOD_CK2_1	444	450	PF00069	0.581
MOD_CK2_1	488	494	PF00069	0.663
MOD_GlcNHglycan	105	108	PF01048	0.560
MOD_GlcNHglycan	109	112	PF01048	0.696
MOD_GlcNHglycan	153	156	PF01048	0.631
MOD_GlcNHglycan	203	206	PF01048	0.571
MOD_GlcNHglycan	264	267	PF01048	0.741
MOD_GlcNHglycan	306	309	PF01048	0.567
MOD_GlcNHglycan	339	342	PF01048	0.655
MOD_GlcNHglycan	350	353	PF01048	0.622
MOD_GlcNHglycan	394	397	PF01048	0.707
MOD_GlcNHglycan	424	427	PF01048	0.684
MOD_GlcNHglycan	435	438	PF01048	0.676
MOD_GlcNHglycan	446	449	PF01048	0.642
MOD_GlcNHglycan	46	49	PF01048	0.584
MOD_GlcNHglycan	490	493	PF01048	0.769
MOD_GlcNHglycan	520	523	PF01048	0.645
MOD_GlcNHglycan	531	534	PF01048	0.677
MOD_GlcNHglycan	542	545	PF01048	0.602
MOD_GlcNHglycan	569	573	PF01048	0.610
MOD_GlcNHglycan	593	596	PF01048	0.835
MOD_GlcNHglycan	600	603	PF01048	0.683
MOD_GlcNHglycan	618	621	PF01048	0.499
MOD_GlcNHglycan	622	625	PF01048	0.668
MOD_GlcNHglycan	635	638	PF01048	0.516
MOD_GlcNHglycan	65	68	PF01048	0.367
MOD_GlcNHglycan	659	662	PF01048	0.525
MOD_GSK3_1	164	171	PF00069	0.568
MOD_GSK3_1	204	211	PF00069	0.673
MOD_GSK3_1	214	221	PF00069	0.674
MOD_GSK3_1	246	253	PF00069	0.643
MOD_GSK3_1	258	265	PF00069	0.693
MOD_GSK3_1	268	275	PF00069	0.606
MOD_GSK3_1	300	307	PF00069	0.620
MOD_GSK3_1	358	365	PF00069	0.599
MOD_GSK3_1	403	410	PF00069	0.613
MOD_GSK3_1	454	461	PF00069	0.559
MOD_GSK3_1	499	506	PF00069	0.637
MOD_GSK3_1	550	557	PF00069	0.582
MOD_GSK3_1	576	583	PF00069	0.635
MOD_GSK3_1	598	605	PF00069	0.728
MOD_GSK3_1	616	623	PF00069	0.528
MOD_GSK3_1	625	632	PF00069	0.679
MOD_GSK3_1	99	106	PF00069	0.738
MOD_N-GLC_1	44	49	PF02516	0.693
MOD_N-GLC_1	85	90	PF02516	0.701
MOD_N-GLC_2	296	298	PF02516	0.570
MOD_NEK2_1	256	261	PF00069	0.558
MOD_NEK2_1	289	294	PF00069	0.587
MOD_NEK2_1	321	326	PF00069	0.749
MOD_NEK2_1	337	342	PF00069	0.537
MOD_NEK2_1	358	363	PF00069	0.562
MOD_NEK2_1	433	438	PF00069	0.751
MOD_NEK2_1	454	459	PF00069	0.564
MOD_NEK2_1	529	534	PF00069	0.713
MOD_NEK2_1	550	555	PF00069	0.594
MOD_NEK2_1	604	609	PF00069	0.611
MOD_NEK2_1	629	634	PF00069	0.673
MOD_NEK2_1	654	659	PF00069	0.745
MOD_PIKK_1	268	274	PF00454	0.735
MOD_PIKK_1	27	33	PF00454	0.556
MOD_PKA_2	135	141	PF00069	0.677
MOD_PKA_2	211	217	PF00069	0.795
MOD_PKB_1	134	142	PF00069	0.739
MOD_Plk_1	21	27	PF00069	0.621
MOD_Plk_1	256	262	PF00069	0.744
MOD_Plk_1	272	278	PF00069	0.527
MOD_Plk_1	6	12	PF00069	0.560
MOD_Plk_2-3	252	258	PF00069	0.568
MOD_Plk_4	211	217	PF00069	0.736
MOD_Plk_4	362	368	PF00069	0.736
MOD_Plk_4	458	464	PF00069	0.661
MOD_Plk_4	554	560	PF00069	0.771
MOD_ProDKin_1	168	174	PF00069	0.551
MOD_ProDKin_1	332	338	PF00069	0.624
MOD_ProDKin_1	407	413	PF00069	0.735
MOD_ProDKin_1	503	509	PF00069	0.660
MOD_ProDKin_1	593	599	PF00069	0.714
MOD_ProDKin_1	623	629	PF00069	0.577
MOD_ProDKin_1	85	91	PF00069	0.587
MOD_ProDKin_1	92	98	PF00069	0.637
MOD_ProDKin_1	99	105	PF00069	0.675
MOD_SUMO_for_1	590	593	PF00179	0.760
MOD_SUMO_rev_2	386	396	PF00179	0.585
MOD_SUMO_rev_2	482	492	PF00179	0.580
TRG_ENDOCYTIC_2	142	145	PF00928	0.568
TRG_ENDOCYTIC_2	190	193	PF00928	0.720
TRG_ENDOCYTIC_2	62	65	PF00928	0.673
TRG_ENDOCYTIC_2	87	90	PF00928	0.645
TRG_ER_diArg_1	132	134	PF00400	0.738
TRG_ER_diArg_1	228	231	PF00400	0.769
TRG_ER_diArg_1	241	244	PF00400	0.588
TRG_ER_diArg_1	55	57	PF00400	0.583
TRG_NLS_MonoCore_2	226	231	PF00514	0.741
TRG_NLS_MonoExtC_3	587	593	PF00514	0.594

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IEM6	Leishmania donovani	65%	99%
A4I4X1	Leishmania infantum	61%	100%
E9AEC0	Leishmania major	66%	100%
E9ALG6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	66%	100%