Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania braziliensis

UniProt:

A4HHM2_LEIBR

TriTrypDb:

LbrM.29.2200 , LBRM2903_260017500

Length:

284

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

A4HHM2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HHM2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_KEX2_1	138	140	PF00082	0.660
CLV_PCSK_PC1ET2_1	138	140	PF00082	0.660
CLV_PCSK_SKI1_1	135	139	PF00082	0.654
CLV_PCSK_SKI1_1	33	37	PF00082	0.638
CLV_PCSK_SKI1_1	67	71	PF00082	0.620
CLV_PCSK_SKI1_1	73	77	PF00082	0.569
CLV_Separin_Metazoa	277	281	PF03568	0.802
DOC_CDC14_PxL_1	76	84	PF14671	0.845
DOC_CYCLIN_yCln2_LP_2	75	81	PF00134	0.847
DOC_MAPK_gen_1	3	11	PF00069	0.839
DOC_MAPK_MEF2A_6	189	198	PF00069	0.650
DOC_MAPK_MEF2A_6	222	230	PF00069	0.565
DOC_PP4_FxxP_1	21	24	PF00568	0.840
DOC_PP4_FxxP_1	223	226	PF00568	0.553
DOC_USP7_MATH_1	116	120	PF00917	0.846
DOC_USP7_MATH_1	124	128	PF00917	0.743
DOC_USP7_MATH_1	137	141	PF00917	0.694
DOC_USP7_MATH_1	150	154	PF00917	0.704
DOC_USP7_MATH_1	158	162	PF00917	0.754
DOC_USP7_MATH_1	61	65	PF00917	0.806
DOC_WW_Pin1_4	38	43	PF00397	0.813
DOC_WW_Pin1_4	80	85	PF00397	0.844
LIG_14-3-3_CanoR_1	189	196	PF00244	0.729
LIG_BRCT_BRCA1_1	245	249	PF00533	0.549
LIG_FHA_1	189	195	PF00498	0.730
LIG_FHA_2	164	170	PF00498	0.851
LIG_FHA_2	39	45	PF00498	0.810
LIG_GBD_Chelix_1	46	54	PF00786	0.589
LIG_LIR_Nem_3	178	184	PF02991	0.839
LIG_LIR_Nem_3	246	252	PF02991	0.549
LIG_MYND_1	80	84	PF01753	0.843
LIG_NRBOX	45	51	PF00104	0.794
LIG_Pex14_2	206	210	PF04695	0.549
LIG_REV1ctd_RIR_1	249	259	PF16727	0.549
LIG_SH2_STAT5	95	98	PF00017	0.802
LIG_SH3_3	14	20	PF00018	0.833
LIG_SH3_3	179	185	PF00018	0.832
LIG_SH3_3	21	27	PF00018	0.750
LIG_SH3_3	75	81	PF00018	0.847
LIG_TRAF2_1	176	179	PF00917	0.852
LIG_TRAF2_2	84	89	PF00917	0.827
MOD_CDK_SPxxK_3	38	45	PF00069	0.813
MOD_CK1_1	262	268	PF00069	0.766
MOD_CK2_1	163	169	PF00069	0.852
MOD_GlcNHglycan	122	125	PF01048	0.641
MOD_GlcNHglycan	152	155	PF01048	0.658
MOD_GlcNHglycan	160	163	PF01048	0.554
MOD_GlcNHglycan	169	173	PF01048	0.431
MOD_GlcNHglycan	201	204	PF01048	0.549
MOD_GlcNHglycan	271	274	PF01048	0.597
MOD_GSK3_1	102	109	PF00069	0.803
MOD_GSK3_1	116	123	PF00069	0.669
MOD_GSK3_1	152	159	PF00069	0.853
MOD_GSK3_1	180	187	PF00069	0.816
MOD_GSK3_1	265	272	PF00069	0.785
MOD_N-GLC_1	120	125	PF02516	0.641
MOD_NEK2_1	106	111	PF00069	0.816
MOD_NEK2_1	199	204	PF00069	0.549
MOD_NEK2_1	205	210	PF00069	0.444
MOD_NEK2_1	244	249	PF00069	0.549
MOD_NEK2_1	35	40	PF00069	0.828
MOD_OFUCOSY	207	214	PF10250	0.549
MOD_PIKK_1	152	158	PF00454	0.853
MOD_PIKK_1	259	265	PF00454	0.692
MOD_PKA_2	188	194	PF00069	0.738
MOD_Plk_4	102	108	PF00069	0.802
MOD_Plk_4	160	166	PF00069	0.852
MOD_Plk_4	205	211	PF00069	0.549
MOD_Plk_4	244	250	PF00069	0.549
MOD_ProDKin_1	38	44	PF00069	0.813
MOD_ProDKin_1	80	86	PF00069	0.842
MOD_SUMO_rev_2	89	96	PF00179	0.808
TRG_DiLeu_BaEn_4	65	71	PF01217	0.819
TRG_ER_diArg_1	228	231	PF00400	0.587
TRG_ER_diArg_1	97	100	PF00400	0.804