LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HHG6_LEIBR
TriTrypDb:
LbrM.29.1630 , LBRM2903_290023300
Length:
192

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HHG6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HHG6

PDB structure(s): 7ane_g

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 15 17 PF00675 0.453
CLV_NRD_NRD_1 97 99 PF00675 0.433
CLV_PCSK_KEX2_1 96 98 PF00082 0.438
CLV_PCSK_SKI1_1 114 118 PF00082 0.416
DEG_Nend_UBRbox_3 1 3 PF02207 0.692
DOC_MAPK_DCC_7 159 169 PF00069 0.488
LIG_14-3-3_CanoR_1 159 165 PF00244 0.518
LIG_14-3-3_CanoR_1 16 24 PF00244 0.579
LIG_FHA_1 113 119 PF00498 0.415
LIG_FHA_1 2 8 PF00498 0.635
LIG_FHA_1 39 45 PF00498 0.489
LIG_LIR_Gen_1 106 113 PF02991 0.438
LIG_LIR_Nem_3 106 110 PF02991 0.419
LIG_LIR_Nem_3 151 157 PF02991 0.503
LIG_Pex14_2 185 189 PF04695 0.441
LIG_PTB_Apo_2 179 186 PF02174 0.403
LIG_SH2_CRK 154 158 PF00017 0.480
LIG_SH2_STAT5 63 66 PF00017 0.409
LIG_SUMO_SIM_par_1 51 57 PF11976 0.448
LIG_TRAF2_1 148 151 PF00917 0.366
MOD_CK1_1 18 24 PF00069 0.562
MOD_CK1_1 82 88 PF00069 0.433
MOD_GSK3_1 18 25 PF00069 0.467
MOD_LATS_1 15 21 PF00433 0.577
MOD_N-GLC_1 146 151 PF02516 0.514
MOD_N-GLC_1 38 43 PF02516 0.544
MOD_N-GLC_1 82 87 PF02516 0.464
MOD_NEK2_1 1 6 PF00069 0.612
MOD_NEK2_1 103 108 PF00069 0.438
MOD_NEK2_1 22 27 PF00069 0.505
MOD_NEK2_1 74 79 PF00069 0.437
MOD_PIKK_1 124 130 PF00454 0.548
MOD_PIKK_1 146 152 PF00454 0.373
MOD_PKA_2 15 21 PF00069 0.533
MOD_PKA_2 22 28 PF00069 0.487
MOD_Plk_1 38 44 PF00069 0.549
MOD_Plk_4 103 109 PF00069 0.423
MOD_Plk_4 51 57 PF00069 0.468
MOD_SUMO_rev_2 82 89 PF00179 0.448
TRG_DiLeu_BaEn_1 121 126 PF01217 0.540
TRG_DiLeu_BaLyEn_6 3 8 PF01217 0.701
TRG_ENDOCYTIC_2 154 157 PF00928 0.528
TRG_ER_diArg_1 66 69 PF00400 0.421
TRG_ER_diArg_1 95 98 PF00400 0.439
TRG_Pf-PMV_PEXEL_1 117 121 PF00026 0.529

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P947 Leptomonas seymouri 84% 100%
A0A0S4KFE4 Bodo saltans 59% 100%
A0A1X0P098 Trypanosomatidae 73% 99%
A0A3S7X2N0 Leishmania donovani 91% 100%
A0A422NEG3 Trypanosoma rangeli 75% 100%
A4I4L5 Leishmania infantum 91% 100%
C9ZLA3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 74% 99%
E9AE13 Leishmania major 92% 100%
E9ALS0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 93% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS