Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HHE0_LEIBR

TriTrypDb:

LbrM.29.1370 , LBRM2903_290020200

Length:

118


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0043233	organelle lumen	3	1
GO:0070013	intracellular organelle lumen	4	1
GO:0110165	cellular anatomical entity	1	1

A4HHE0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HHE0


Leishmania	From	To	Domain/Motif	Score
DOC_PP1_RVXF_1	40	47	PF00149	0.614
DOC_PP2B_LxvP_1	23	26	PF13499	0.539
DOC_USP7_MATH_1	11	15	PF00917	0.642
DOC_USP7_MATH_1	24	28	PF00917	0.575
DOC_USP7_UBL2_3	114	118	PF12436	0.690
LIG_14-3-3_CanoR_1	68	73	PF00244	0.567
LIG_BRCT_BRCA1_1	75	79	PF00533	0.543
LIG_deltaCOP1_diTrp_1	29	35	PF00928	0.483
LIG_FHA_1	111	117	PF00498	0.413
LIG_FHA_1	17	23	PF00498	0.593
LIG_FHA_1	62	68	PF00498	0.481
LIG_LIR_Gen_1	40	51	PF02991	0.529
LIG_LIR_Gen_1	97	107	PF02991	0.492
LIG_LIR_Nem_3	40	46	PF02991	0.509
LIG_LIR_Nem_3	48	52	PF02991	0.559
LIG_LIR_Nem_3	97	103	PF02991	0.511
LIG_Pex14_1	32	36	PF04695	0.492
LIG_SH2_SRC	102	105	PF00017	0.375
LIG_SH2_STAT5	102	105	PF00017	0.375
LIG_SUMO_SIM_par_1	18	30	PF11976	0.628
LIG_TRAF2_1	86	89	PF00917	0.636
LIG_WRC_WIRS_1	46	51	PF05994	0.556
MOD_CK1_1	27	33	PF00069	0.590
MOD_CK1_1	66	72	PF00069	0.573
MOD_CK2_1	83	89	PF00069	0.568
MOD_CMANNOS	32	35	PF00535	0.477
MOD_GlcNHglycan	32	35	PF01048	0.553
MOD_GlcNHglycan	75	78	PF01048	0.598
MOD_GSK3_1	1	8	PF00069	0.692
MOD_GSK3_1	11	18	PF00069	0.558
MOD_GSK3_1	110	117	PF00069	0.578
MOD_GSK3_1	59	66	PF00069	0.616
MOD_N-GLC_1	59	64	PF02516	0.719
MOD_NEK2_1	1	6	PF00069	0.704
MOD_NEK2_1	110	115	PF00069	0.613
MOD_NEK2_1	61	66	PF00069	0.615
MOD_PIKK_1	105	111	PF00454	0.585
MOD_PK_1	63	69	PF00069	0.685
MOD_Plk_1	96	102	PF00069	0.529
MOD_Plk_2-3	45	51	PF00069	0.580
MOD_Plk_4	11	17	PF00069	0.664
MOD_Plk_4	27	33	PF00069	0.415
MOD_SUMO_rev_2	38	44	PF00179	0.574


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I688	Leptomonas seymouri	72%	100%
A0A1X0NZR9	Trypanosomatidae	49%	84%
A0A3Q8IH91	Leishmania donovani	92%	100%
A0A3R7RKT9	Trypanosoma rangeli	52%	81%
A4I4I6	Leishmania infantum	92%	100%
C9ZL73	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	58%	86%
E9ADY7	Leishmania major	91%	100%
E9ALU4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%