Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HHD3_LEIBR

TriTrypDb:

LbrM.29.1290 , LBRM2903_290019200

Length:

374

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Show entries

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0043233	organelle lumen	3	1
GO:0070013	intracellular organelle lumen	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

A4HHD3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HHD3

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	132	136	PF00656	0.484
CLV_C14_Caspase3-7	342	346	PF00656	0.628
CLV_NRD_NRD_1	144	146	PF00675	0.511
CLV_NRD_NRD_1	280	282	PF00675	0.648
CLV_NRD_NRD_1	331	333	PF00675	0.646
CLV_NRD_NRD_1	348	350	PF00675	0.606
CLV_PCSK_KEX2_1	111	113	PF00082	0.548
CLV_PCSK_KEX2_1	144	146	PF00082	0.550
CLV_PCSK_KEX2_1	279	281	PF00082	0.600
CLV_PCSK_KEX2_1	331	333	PF00082	0.640

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6E7	Leptomonas seymouri	40%	100%
A0A0S4KK84	Bodo saltans	25%	98%
A0A1X0NZS1	Trypanosomatidae	28%	91%
A0A3Q8IFC4	Leishmania donovani	74%	99%
A0A3R7LZ67	Trypanosoma rangeli	30%	93%
A4I4H8	Leishmania infantum	74%	99%
E9ADX9	Leishmania major	73%	100%
E9ALV2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	75%	100%
V5BR99	Trypanosoma cruzi	30%	92%

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