Pribosyltran domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HH89_LEIBR

TriTrypDb:

LbrM.29.0840 , LBRM2903_290014800

Length:

616

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

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Expansion

Sequence features

A4HH89

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HH89

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	141	145	PF00656	0.618
CLV_C14_Caspase3-7	203	207	PF00656	0.685
CLV_C14_Caspase3-7	209	213	PF00656	0.675
CLV_C14_Caspase3-7	304	308	PF00656	0.666
CLV_C14_Caspase3-7	552	556	PF00656	0.529
CLV_NRD_NRD_1	289	291	PF00675	0.382
CLV_NRD_NRD_1	467	469	PF00675	0.416
CLV_NRD_NRD_1	470	472	PF00675	0.425
CLV_NRD_NRD_1	530	532	PF00675	0.449
CLV_NRD_NRD_1	567	569	PF00675	0.408

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I7X5	Leptomonas seymouri	44%	100%
A0A3S7X291	Leishmania donovani	73%	100%
A4I4D5	Leishmania infantum	72%	100%
E9ADT4	Leishmania major	72%	100%
E9ALZ6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	70%	100%

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