DNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

DNA helicase

Gene product:

tfiih basal transcription factor complex helicase xpb subunit

Species:

Leishmania braziliensis

UniProt:

A4HH67_LEIBR

TriTrypDb:

LbrM.29.0600 , LBRM2903_290012100 , LBRM2903_290012200

Length:

1108

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0000109	nucleotide-excision repair complex	3	2
GO:0000112	nucleotide-excision repair factor 3 complex	4	2
GO:0005634	nucleus	5	1
GO:0005654	nucleoplasm	2	1
GO:0005667	transcription regulator complex	2	2
GO:0005675	transcription factor TFIIH holo complex	4	2
GO:0005737	cytoplasm	2	1
GO:0032806	carboxy-terminal domain protein kinase complex	3	2
GO:0032991	protein-containing complex	1	2
GO:0032993	protein-DNA complex	2	2
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0061695	transferase complex, transferring phosphorus-containing groups	4	2
GO:0090575	RNA polymerase II transcription regulator complex	3	2
GO:0097550	transcription preinitiation complex	3	2
GO:0110165	cellular anatomical entity	1	1
GO:0140513	nuclear protein-containing complex	2	2
GO:1902494	catalytic complex	2	2
GO:1902554	serine/threonine protein kinase complex	6	2
GO:1902911	protein kinase complex	5	2
GO:1990234	transferase complex	3	2

Expansion

Sequence features

A4HH67

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HH67

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	4
GO:0006352	DNA-templated transcription initiation	6	4
GO:0006367	transcription initiation at RNA polymerase II promoter	7	4
GO:0006725	cellular aromatic compound metabolic process	3	4
GO:0006807	nitrogen compound metabolic process	2	4
GO:0008152	metabolic process	1	4
GO:0009058	biosynthetic process	2	4
GO:0009059	macromolecule biosynthetic process	4	4
GO:0009987	cellular process	1	4
GO:0016070	RNA metabolic process	5	4
GO:0018130	heterocycle biosynthetic process	4	4
GO:0019438	aromatic compound biosynthetic process	4	4
GO:0032774	RNA biosynthetic process	5	4
GO:0033683	obsolete nucleotide-excision repair, DNA incision	6	2
GO:0034641	cellular nitrogen compound metabolic process	3	4
GO:0034654	nucleobase-containing compound biosynthetic process	4	4
GO:0043170	macromolecule metabolic process	3	4
GO:0044237	cellular metabolic process	2	4
GO:0044238	primary metabolic process	2	4
GO:0044249	cellular biosynthetic process	3	4
GO:0044271	cellular nitrogen compound biosynthetic process	4	4
GO:0046483	heterocycle metabolic process	3	4
GO:0071704	organic substance metabolic process	2	4
GO:0090304	nucleic acid metabolic process	4	4
GO:0090305	nucleic acid phosphodiester bond hydrolysis	5	2
GO:1901360	organic cyclic compound metabolic process	3	4
GO:1901362	organic cyclic compound biosynthetic process	4	4
GO:1901576	organic substance biosynthetic process	3	4
GO:0006259	DNA metabolic process	4	2
GO:0006281	DNA repair	5	2
GO:0006289	nucleotide-excision repair	6	2
GO:0006950	response to stress	2	2
GO:0006974	DNA damage response	4	2
GO:0033554	cellular response to stress	3	2
GO:0044260	obsolete cellular macromolecule metabolic process	3	2
GO:0050896	response to stimulus	1	2
GO:0051716	cellular response to stimulus	2	2

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	11
GO:0003676	nucleic acid binding	3	11
GO:0003677	DNA binding	4	11
GO:0003678	DNA helicase activity	3	11
GO:0003824	catalytic activity	1	11
GO:0004386	helicase activity	2	11
GO:0005488	binding	1	11
GO:0005524	ATP binding	5	11
GO:0008094	ATP-dependent activity, acting on DNA	2	11
GO:0016787	hydrolase activity	2	11
GO:0017076	purine nucleotide binding	4	11
GO:0030554	adenyl nucleotide binding	5	11
GO:0032553	ribonucleotide binding	3	11
GO:0032555	purine ribonucleotide binding	4	11
GO:0032559	adenyl ribonucleotide binding	5	11
GO:0035639	purine ribonucleoside triphosphate binding	4	11
GO:0036094	small molecule binding	2	11
GO:0043167	ion binding	2	11
GO:0043168	anion binding	3	11
GO:0097159	organic cyclic compound binding	2	11
GO:0097367	carbohydrate derivative binding	2	11
GO:0140097	catalytic activity, acting on DNA	3	11
GO:0140640	catalytic activity, acting on a nucleic acid	2	11
GO:0140657	ATP-dependent activity	1	11
GO:1901265	nucleoside phosphate binding	3	11
GO:1901363	heterocyclic compound binding	2	11
GO:0003700	DNA-binding transcription factor activity	2	1
GO:0043138	3'-5' DNA helicase activity	4	2
GO:0140110	transcription regulator activity	1	1
GO:0016462	pyrophosphatase activity	5	1
GO:0016817	hydrolase activity, acting on acid anhydrides	3	1
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	1
GO:0016887	ATP hydrolysis activity	7	1
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1035	1039	PF00656	0.494
CLV_C14_Caspase3-7	388	392	PF00656	0.489
CLV_MEL_PAP_1	839	845	PF00089	0.261
CLV_NRD_NRD_1	1060	1062	PF00675	0.403
CLV_NRD_NRD_1	1063	1065	PF00675	0.401
CLV_NRD_NRD_1	295	297	PF00675	0.575
CLV_NRD_NRD_1	493	495	PF00675	0.309
CLV_NRD_NRD_1	719	721	PF00675	0.616
CLV_NRD_NRD_1	866	868	PF00675	0.306
CLV_PCSK_FUR_1	1058	1062	PF00082	0.516
CLV_PCSK_FUR_1	491	495	PF00082	0.257
CLV_PCSK_KEX2_1	1060	1062	PF00082	0.403
CLV_PCSK_KEX2_1	1063	1065	PF00082	0.416
CLV_PCSK_KEX2_1	295	297	PF00082	0.575
CLV_PCSK_KEX2_1	493	495	PF00082	0.257
CLV_PCSK_KEX2_1	540	542	PF00082	0.345
CLV_PCSK_KEX2_1	579	581	PF00082	0.291
CLV_PCSK_KEX2_1	717	719	PF00082	0.648
CLV_PCSK_KEX2_1	866	868	PF00082	0.306
CLV_PCSK_KEX2_1	907	909	PF00082	0.350
CLV_PCSK_PC1ET2_1	540	542	PF00082	0.345
CLV_PCSK_PC1ET2_1	579	581	PF00082	0.350
CLV_PCSK_PC1ET2_1	717	719	PF00082	0.618
CLV_PCSK_PC1ET2_1	907	909	PF00082	0.350
CLV_PCSK_SKI1_1	304	308	PF00082	0.612
CLV_PCSK_SKI1_1	359	363	PF00082	0.391
CLV_PCSK_SKI1_1	372	376	PF00082	0.341
CLV_PCSK_SKI1_1	442	446	PF00082	0.385
CLV_PCSK_SKI1_1	511	515	PF00082	0.306
CLV_PCSK_SKI1_1	541	545	PF00082	0.299
CLV_PCSK_SKI1_1	592	596	PF00082	0.291
CLV_PCSK_SKI1_1	629	633	PF00082	0.391
CLV_PCSK_SKI1_1	697	701	PF00082	0.534
DEG_APCC_DBOX_1	347	355	PF00400	0.403
DEG_APCC_DBOX_1	371	379	PF00400	0.453
DEG_APCC_DBOX_1	591	599	PF00400	0.350
DEG_Nend_UBRbox_3	1	3	PF02207	0.495
DEG_SPOP_SBC_1	153	157	PF00917	0.500
DOC_ANK_TNKS_1	579	586	PF00023	0.247
DOC_CDC14_PxL_1	1019	1027	PF14671	0.509
DOC_CKS1_1	124	129	PF01111	0.441
DOC_CYCLIN_RxL_1	210	223	PF00134	0.518
DOC_CYCLIN_RxL_1	691	702	PF00134	0.349
DOC_CYCLIN_RxL_1	757	766	PF00134	0.391
DOC_MAPK_DCC_7	359	367	PF00069	0.450
DOC_MAPK_DCC_7	466	475	PF00069	0.351
DOC_MAPK_gen_1	1096	1106	PF00069	0.485
DOC_MAPK_gen_1	282	290	PF00069	0.389
DOC_MAPK_gen_1	346	355	PF00069	0.341
DOC_MAPK_gen_1	493	504	PF00069	0.334
DOC_MAPK_gen_1	562	570	PF00069	0.350
DOC_MAPK_gen_1	627	634	PF00069	0.295
DOC_MAPK_HePTP_8	343	355	PF00069	0.332
DOC_MAPK_HePTP_8	463	475	PF00069	0.290
DOC_MAPK_JIP1_4	401	407	PF00069	0.586
DOC_MAPK_MEF2A_6	252	259	PF00069	0.593
DOC_MAPK_MEF2A_6	282	290	PF00069	0.389
DOC_MAPK_MEF2A_6	346	355	PF00069	0.341
DOC_MAPK_MEF2A_6	466	475	PF00069	0.351
DOC_MAPK_MEF2A_6	842	850	PF00069	0.306
DOC_MAPK_NFAT4_5	348	356	PF00069	0.340
DOC_PP1_RVXF_1	1029	1035	PF00149	0.472
DOC_PP1_RVXF_1	1081	1088	PF00149	0.386
DOC_PP1_RVXF_1	788	795	PF00149	0.266
DOC_PP2B_LxvP_1	353	356	PF13499	0.302
DOC_PP2B_LxvP_1	468	471	PF13499	0.395
DOC_PP2B_LxvP_1	808	811	PF13499	0.306
DOC_PP2B_LxvP_1	848	851	PF13499	0.261
DOC_PP4_FxxP_1	206	209	PF00568	0.508
DOC_PP4_FxxP_1	361	364	PF00568	0.341
DOC_USP7_MATH_1	1012	1016	PF00917	0.480
DOC_USP7_MATH_1	117	121	PF00917	0.732
DOC_USP7_MATH_1	153	157	PF00917	0.549
DOC_USP7_MATH_1	246	250	PF00917	0.573
DOC_USP7_MATH_1	309	313	PF00917	0.620
DOC_USP7_MATH_1	588	592	PF00917	0.357
DOC_USP7_MATH_1	704	708	PF00917	0.479
DOC_USP7_MATH_1	758	762	PF00917	0.398
DOC_USP7_MATH_1	851	855	PF00917	0.261
DOC_USP7_MATH_1	900	904	PF00917	0.294
DOC_USP7_MATH_1	956	960	PF00917	0.658
DOC_USP7_MATH_1	983	987	PF00917	0.583
DOC_USP7_UBL2_3	169	173	PF12436	0.654
DOC_USP7_UBL2_3	278	282	PF12436	0.398
DOC_USP7_UBL2_3	359	363	PF12436	0.284
DOC_WW_Pin1_4	1008	1013	PF00397	0.490
DOC_WW_Pin1_4	1052	1057	PF00397	0.483
DOC_WW_Pin1_4	123	128	PF00397	0.542
DOC_WW_Pin1_4	157	162	PF00397	0.571
DOC_WW_Pin1_4	208	213	PF00397	0.662
DOC_WW_Pin1_4	221	226	PF00397	0.577
DOC_WW_Pin1_4	233	238	PF00397	0.685
DOC_WW_Pin1_4	327	332	PF00397	0.497
DOC_WW_Pin1_4	378	383	PF00397	0.597
DOC_WW_Pin1_4	783	788	PF00397	0.262
LIG_14-3-3_CanoR_1	1013	1022	PF00244	0.675
LIG_14-3-3_CanoR_1	1083	1088	PF00244	0.564
LIG_14-3-3_CanoR_1	252	258	PF00244	0.584
LIG_14-3-3_CanoR_1	372	382	PF00244	0.465
LIG_14-3-3_CanoR_1	695	700	PF00244	0.387
LIG_14-3-3_CanoR_1	70	79	PF00244	0.297
LIG_14-3-3_CanoR_1	763	772	PF00244	0.393
LIG_14-3-3_CanoR_1	908	912	PF00244	0.285
LIG_14-3-3_CanoR_1	980	988	PF00244	0.356
LIG_14-3-3_CanoR_1	997	1003	PF00244	0.554
LIG_Actin_WH2_2	347	365	PF00022	0.294
LIG_Actin_WH2_2	750	765	PF00022	0.351
LIG_ActinCP_TwfCPI_2	206	215	PF01115	0.482
LIG_APCC_ABBAyCdc20_2	346	352	PF00400	0.312
LIG_APCC_ABBAyCdc20_2	720	726	PF00400	0.614
LIG_APCC_ABBAyCdc20_2	790	796	PF00400	0.261
LIG_BRCT_BRCA1_1	118	122	PF00533	0.558
LIG_BRCT_BRCA1_1	155	159	PF00533	0.507
LIG_Clathr_ClatBox_1	605	609	PF01394	0.341
LIG_deltaCOP1_diTrp_1	1028	1034	PF00928	0.402
LIG_FHA_1	1043	1049	PF00498	0.485
LIG_FHA_1	136	142	PF00498	0.768
LIG_FHA_1	212	218	PF00498	0.607
LIG_FHA_1	384	390	PF00498	0.560
LIG_FHA_1	465	471	PF00498	0.415
LIG_FHA_1	522	528	PF00498	0.400
LIG_FHA_1	54	60	PF00498	0.297
LIG_FHA_1	556	562	PF00498	0.374
LIG_FHA_1	694	700	PF00498	0.579
LIG_FHA_1	773	779	PF00498	0.262
LIG_FHA_1	897	903	PF00498	0.327
LIG_FHA_1	997	1003	PF00498	0.602
LIG_FHA_2	328	334	PF00498	0.486
LIG_FHA_2	414	420	PF00498	0.564
LIG_FHA_2	548	554	PF00498	0.250
LIG_FHA_2	71	77	PF00498	0.309
LIG_IBAR_NPY_1	768	770	PF08397	0.291
LIG_LIR_Apic_2	360	364	PF02991	0.348
LIG_LIR_Gen_1	446	456	PF02991	0.443
LIG_LIR_Gen_1	457	468	PF02991	0.342
LIG_LIR_Gen_1	571	578	PF02991	0.338
LIG_LIR_Gen_1	658	669	PF02991	0.390
LIG_LIR_Gen_1	930	938	PF02991	0.461
LIG_LIR_Nem_3	1042	1046	PF02991	0.381
LIG_LIR_Nem_3	410	414	PF02991	0.453
LIG_LIR_Nem_3	446	452	PF02991	0.409
LIG_LIR_Nem_3	457	463	PF02991	0.355
LIG_LIR_Nem_3	571	576	PF02991	0.338
LIG_LIR_Nem_3	625	631	PF02991	0.301
LIG_LIR_Nem_3	658	664	PF02991	0.386
LIG_LIR_Nem_3	689	693	PF02991	0.479
LIG_LIR_Nem_3	930	934	PF02991	0.447
LIG_LYPXL_SIV_4	17	25	PF13949	0.350
LIG_LYPXL_yS_3	1022	1025	PF13949	0.509
LIG_Pex14_1	1030	1034	PF04695	0.448
LIG_Pex14_1	539	543	PF04695	0.261
LIG_Rb_LxCxE_1	23	39	PF01857	0.294
LIG_SH2_CRK	460	464	PF00017	0.270
LIG_SH2_CRK	573	577	PF00017	0.338
LIG_SH2_CRK	628	632	PF00017	0.291
LIG_SH2_CRK	892	896	PF00017	0.306
LIG_SH2_CRK	919	923	PF00017	0.291
LIG_SH2_NCK_1	892	896	PF00017	0.306
LIG_SH2_SRC	18	21	PF00017	0.309
LIG_SH2_SRC	460	463	PF00017	0.293
LIG_SH2_SRC	756	759	PF00017	0.355
LIG_SH2_STAP1	133	137	PF00017	0.445
LIG_SH2_STAP1	18	22	PF00017	0.350
LIG_SH2_STAP1	57	61	PF00017	0.291
LIG_SH2_STAP1	573	577	PF00017	0.400
LIG_SH2_STAP1	657	661	PF00017	0.382
LIG_SH2_STAT3	341	344	PF00017	0.439
LIG_SH2_STAT3	432	435	PF00017	0.371
LIG_SH2_STAT3	906	909	PF00017	0.291
LIG_SH2_STAT5	341	344	PF00017	0.350
LIG_SH2_STAT5	462	465	PF00017	0.307
LIG_SH2_STAT5	469	472	PF00017	0.342
LIG_SH2_STAT5	756	759	PF00017	0.355
LIG_SH2_STAT5	797	800	PF00017	0.350
LIG_SH2_STAT5	828	831	PF00017	0.261
LIG_SH2_STAT5	890	893	PF00017	0.261
LIG_SH3_2	1053	1058	PF14604	0.480
LIG_SH3_3	1050	1056	PF00018	0.485
LIG_SH3_3	121	127	PF00018	0.451
LIG_SH3_3	194	200	PF00018	0.586
LIG_SH3_3	206	212	PF00018	0.551
LIG_SH3_3	219	225	PF00018	0.602
LIG_SH3_3	256	262	PF00018	0.493
LIG_SH3_3	286	292	PF00018	0.425
LIG_SH3_3	675	681	PF00018	0.356
LIG_SH3_3	876	882	PF00018	0.281
LIG_SH3_3	938	944	PF00018	0.381
LIG_SH3_CIN85_PxpxPR_1	205	210	PF14604	0.503
LIG_Sin3_3	985	992	PF02671	0.390
LIG_SUMO_SIM_anti_2	256	261	PF11976	0.553
LIG_SUMO_SIM_par_1	1044	1050	PF11976	0.448
LIG_SUMO_SIM_par_1	604	610	PF11976	0.306
LIG_SUMO_SIM_par_1	76	82	PF11976	0.293
LIG_TRAF2_1	1015	1018	PF00917	0.501
LIG_TRAF2_1	587	590	PF00917	0.350
LIG_TRAF2_1	73	76	PF00917	0.294
LIG_TYR_ITIM	626	631	PF00017	0.291
LIG_TYR_ITSM	569	576	PF00017	0.350
LIG_UBA3_1	272	278	PF00899	0.423
MOD_CDC14_SPxK_1	1055	1058	PF00782	0.468
MOD_CDK_SPK_2	1008	1013	PF00069	0.465
MOD_CDK_SPxK_1	1052	1058	PF00069	0.479
MOD_CDK_SPxxK_3	123	130	PF00069	0.446
MOD_CDK_SPxxK_3	157	164	PF00069	0.491
MOD_CDK_SPxxK_3	208	215	PF00069	0.561
MOD_CDK_SPxxK_3	327	334	PF00069	0.483
MOD_CDK_SPxxK_3	783	790	PF00069	0.261
MOD_CK1_1	1026	1032	PF00069	0.427
MOD_CK1_1	211	217	PF00069	0.643
MOD_CK1_1	418	424	PF00069	0.482
MOD_CK1_1	425	431	PF00069	0.442
MOD_CK1_1	46	52	PF00069	0.295
MOD_CK1_1	896	902	PF00069	0.325
MOD_CK1_1	97	103	PF00069	0.615
MOD_CK2_1	1012	1018	PF00069	0.507
MOD_CK2_1	190	196	PF00069	0.563
MOD_CK2_1	24	30	PF00069	0.282
MOD_CK2_1	413	419	PF00069	0.682
MOD_CK2_1	547	553	PF00069	0.228
MOD_CK2_1	70	76	PF00069	0.193
MOD_CK2_1	815	821	PF00069	0.291
MOD_CK2_1	957	963	PF00069	0.580
MOD_Cter_Amidation	715	718	PF01082	0.607
MOD_DYRK1A_RPxSP_1	208	212	PF00069	0.483
MOD_DYRK1A_RPxSP_1	221	225	PF00069	0.458
MOD_GlcNHglycan	1035	1038	PF01048	0.396
MOD_GlcNHglycan	1074	1077	PF01048	0.471
MOD_GlcNHglycan	148	151	PF01048	0.690
MOD_GlcNHglycan	185	188	PF01048	0.761
MOD_GlcNHglycan	192	195	PF01048	0.795
MOD_GlcNHglycan	248	251	PF01048	0.509
MOD_GlcNHglycan	311	314	PF01048	0.572
MOD_GlcNHglycan	48	51	PF01048	0.264
MOD_GlcNHglycan	5	8	PF01048	0.468
MOD_GlcNHglycan	634	637	PF01048	0.261
MOD_GlcNHglycan	708	711	PF01048	0.493
MOD_GlcNHglycan	859	862	PF01048	0.261
MOD_GlcNHglycan	954	957	PF01048	0.612
MOD_GlcNHglycan	981	984	PF01048	0.444
MOD_GlcNHglycan	985	988	PF01048	0.408
MOD_GlcNHglycan	99	102	PF01048	0.551
MOD_GSK3_1	1008	1015	PF00069	0.498
MOD_GSK3_1	1026	1033	PF00069	0.603
MOD_GSK3_1	1079	1086	PF00069	0.565
MOD_GSK3_1	112	119	PF00069	0.678
MOD_GSK3_1	137	144	PF00069	0.566
MOD_GSK3_1	153	160	PF00069	0.659
MOD_GSK3_1	167	174	PF00069	0.515
MOD_GSK3_1	307	314	PF00069	0.626
MOD_GSK3_1	415	422	PF00069	0.550
MOD_GSK3_1	42	49	PF00069	0.285
MOD_GSK3_1	518	525	PF00069	0.295
MOD_GSK3_1	695	702	PF00069	0.542
MOD_GSK3_1	704	711	PF00069	0.649
MOD_GSK3_1	880	887	PF00069	0.269
MOD_GSK3_1	896	903	PF00069	0.355
MOD_GSK3_1	952	959	PF00069	0.641
MOD_GSK3_1	979	986	PF00069	0.367
MOD_GSK3_1	998	1005	PF00069	0.487
MOD_LATS_1	162	168	PF00433	0.481
MOD_LATS_1	68	74	PF00433	0.193
MOD_N-GLC_1	164	169	PF02516	0.488
MOD_N-GLC_1	384	389	PF02516	0.455
MOD_N-GLC_1	471	476	PF02516	0.364
MOD_N-GLC_1	532	537	PF02516	0.299
MOD_N-GLC_1	97	102	PF02516	0.685
MOD_N-GLC_2	886	888	PF02516	0.291
MOD_NEK2_1	106	111	PF00069	0.628
MOD_NEK2_1	1067	1072	PF00069	0.551
MOD_NEK2_1	137	142	PF00069	0.619
MOD_NEK2_1	24	29	PF00069	0.282
MOD_NEK2_1	300	305	PF00069	0.522
MOD_NEK2_1	307	312	PF00069	0.515
MOD_NEK2_1	342	347	PF00069	0.401
MOD_NEK2_1	43	48	PF00069	0.261
MOD_NEK2_1	522	527	PF00069	0.300
MOD_NEK2_1	569	574	PF00069	0.299
MOD_NEK2_1	632	637	PF00069	0.307
MOD_NEK2_1	662	667	PF00069	0.350
MOD_NEK2_1	699	704	PF00069	0.522
MOD_NEK2_1	772	777	PF00069	0.263
MOD_NEK2_1	862	867	PF00069	0.261
MOD_NEK2_1	884	889	PF00069	0.291
MOD_NEK2_1	952	957	PF00069	0.579
MOD_NEK2_2	117	122	PF00069	0.456
MOD_NEK2_2	154	159	PF00069	0.505
MOD_NEK2_2	758	763	PF00069	0.307
MOD_NEK2_2	998	1003	PF00069	0.625
MOD_PIKK_1	106	112	PF00454	0.562
MOD_PIKK_1	238	244	PF00454	0.563
MOD_PIKK_1	32	38	PF00454	0.294
MOD_PIKK_1	772	778	PF00454	0.263
MOD_PIKK_1	893	899	PF00454	0.291
MOD_PK_1	719	725	PF00069	0.577
MOD_PKA_1	719	725	PF00069	0.577
MOD_PKA_1	907	913	PF00069	0.350
MOD_PKA_2	1012	1018	PF00069	0.422
MOD_PKA_2	1095	1101	PF00069	0.520
MOD_PKA_2	146	152	PF00069	0.521
MOD_PKA_2	220	226	PF00069	0.466
MOD_PKA_2	393	399	PF00069	0.477
MOD_PKA_2	419	425	PF00069	0.469
MOD_PKA_2	544	550	PF00069	0.261
MOD_PKA_2	719	725	PF00069	0.670
MOD_PKA_2	815	821	PF00069	0.348
MOD_PKA_2	907	913	PF00069	0.302
MOD_PKA_2	979	985	PF00069	0.300
MOD_PKA_2	996	1002	PF00069	0.489
MOD_Plk_1	164	170	PF00069	0.572
MOD_Plk_1	43	49	PF00069	0.350
MOD_Plk_1	464	470	PF00069	0.462
MOD_Plk_1	471	477	PF00069	0.403
MOD_Plk_1	532	538	PF00069	0.341
MOD_Plk_1	552	558	PF00069	0.259
MOD_Plk_1	983	989	PF00069	0.299
MOD_Plk_4	1042	1048	PF00069	0.611
MOD_Plk_4	1100	1106	PF00069	0.669
MOD_Plk_4	117	123	PF00069	0.456
MOD_Plk_4	137	143	PF00069	0.602
MOD_Plk_4	154	160	PF00069	0.661
MOD_Plk_4	523	529	PF00069	0.299
MOD_Plk_4	532	538	PF00069	0.299
MOD_Plk_4	571	577	PF00069	0.341
MOD_Plk_4	634	640	PF00069	0.319
MOD_Plk_4	719	725	PF00069	0.670
MOD_Plk_4	851	857	PF00069	0.285
MOD_Plk_4	890	896	PF00069	0.312
MOD_Plk_4	907	913	PF00069	0.233
MOD_ProDKin_1	1008	1014	PF00069	0.484
MOD_ProDKin_1	1052	1058	PF00069	0.479
MOD_ProDKin_1	123	129	PF00069	0.537
MOD_ProDKin_1	157	163	PF00069	0.567
MOD_ProDKin_1	208	214	PF00069	0.659
MOD_ProDKin_1	221	227	PF00069	0.577
MOD_ProDKin_1	233	239	PF00069	0.684
MOD_ProDKin_1	327	333	PF00069	0.489
MOD_ProDKin_1	378	384	PF00069	0.600
MOD_ProDKin_1	783	789	PF00069	0.262
MOD_SUMO_for_1	172	175	PF00179	0.681
MOD_SUMO_for_1	277	280	PF00179	0.466
MOD_SUMO_rev_2	279	284	PF00179	0.395
MOD_SUMO_rev_2	387	392	PF00179	0.559
MOD_SUMO_rev_2	641	645	PF00179	0.433
TRG_DiLeu_BaEn_1	180	185	PF01217	0.599
TRG_DiLeu_BaEn_1	821	826	PF01217	0.266
TRG_DiLeu_BaEn_1	984	989	PF01217	0.293
TRG_DiLeu_BaEn_3	589	595	PF01217	0.350
TRG_DiLeu_BaEn_4	180	186	PF01217	0.514
TRG_DiLeu_BaLyEn_6	1020	1025	PF01217	0.517
TRG_DiLeu_BaLyEn_6	250	255	PF01217	0.555
TRG_DiLeu_BaLyEn_6	403	408	PF01217	0.522
TRG_ENDOCYTIC_2	1022	1025	PF00928	0.509
TRG_ENDOCYTIC_2	18	21	PF00928	0.291
TRG_ENDOCYTIC_2	460	463	PF00928	0.405
TRG_ENDOCYTIC_2	573	576	PF00928	0.338
TRG_ENDOCYTIC_2	628	631	PF00928	0.291
TRG_ENDOCYTIC_2	690	693	PF00928	0.396
TRG_ENDOCYTIC_2	892	895	PF00928	0.306
TRG_ENDOCYTIC_2	919	922	PF00928	0.297
TRG_ER_diArg_1	1060	1063	PF00400	0.404
TRG_ER_diArg_1	1093	1096	PF00400	0.484
TRG_ER_diArg_1	207	210	PF00400	0.532
TRG_ER_diArg_1	294	296	PF00400	0.527
TRG_ER_diArg_1	346	349	PF00400	0.343
TRG_ER_diArg_1	479	482	PF00400	0.303
TRG_ER_diArg_1	492	494	PF00400	0.316
TRG_ER_diArg_1	718	720	PF00400	0.584
TRG_ER_diArg_1	744	747	PF00400	0.512
TRG_Pf-PMV_PEXEL_1	130	134	PF00026	0.554
TRG_Pf-PMV_PEXEL_1	267	271	PF00026	0.563
TRG_Pf-PMV_PEXEL_1	406	410	PF00026	0.588
TRG_Pf-PMV_PEXEL_1	592	596	PF00026	0.294
TRG_Pf-PMV_PEXEL_1	920	925	PF00026	0.267
TRG_Pf-PMV_PEXEL_1	926	930	PF00026	0.336

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IM24	Leptomonas seymouri	64%	100%
A0A0S4JHE3	Bodo saltans	40%	100%
A0A3S5H7K7	Leishmania donovani	83%	100%
A0A3S5IRW5	Trypanosoma rangeli	48%	100%
A4I4B1	Leishmania infantum	83%	100%
E9ADR1	Leishmania major	82%	100%
E9AM19	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%
E9B3H0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
Q4Q4N0	Leishmania major	30%	100%