LeishMANIAdb
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Peptidase_S15 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Peptidase_S15 domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HH53_LEIBR
TriTrypDb:
LbrM.29.0460 , LBRM2903_290011300 *
Length:
222

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HH53
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HH53

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 48 52 PF00656 0.566
CLV_PCSK_SKI1_1 216 220 PF00082 0.609
CLV_PCSK_SKI1_1 45 49 PF00082 0.528
DEG_Nend_UBRbox_3 1 3 PF02207 0.687
DEG_ODPH_VHL_1 126 139 PF01847 0.496
DEG_SPOP_SBC_1 207 211 PF00917 0.609
DEG_SPOP_SBC_1 80 84 PF00917 0.526
DOC_CDC14_PxL_1 126 134 PF14671 0.619
DOC_CDC14_PxL_1 30 38 PF14671 0.646
DOC_CYCLIN_RxL_1 213 222 PF00134 0.606
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3Q8IR44 Leishmania donovani 65% 96%
A4I4A4 Leishmania infantum 65% 96%
E9ADQ3 Leishmania major 61% 96%
E9AM27 Leishmania mexicana (strain MHOM/GT/2001/U1103) 63% 96%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS