Contig, possible fusion of chromosomes 20 and 34

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HH47_LEIBR

TriTrypDb:

LbrM.29.0400 , LBRM2903_290010700

Length:

708

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HH47

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HH47

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	701	705	PF00656	0.444
CLV_NRD_NRD_1	123	125	PF00675	0.606
CLV_NRD_NRD_1	167	169	PF00675	0.528
CLV_NRD_NRD_1	289	291	PF00675	0.443
CLV_NRD_NRD_1	341	343	PF00675	0.594
CLV_NRD_NRD_1	497	499	PF00675	0.666
CLV_NRD_NRD_1	558	560	PF00675	0.545
CLV_NRD_NRD_1	603	605	PF00675	0.486
CLV_NRD_NRD_1	606	608	PF00675	0.484
CLV_NRD_NRD_1	624	626	PF00675	0.578
CLV_NRD_NRD_1	642	644	PF00675	0.653
CLV_NRD_NRD_1	694	696	PF00675	0.532
CLV_PCSK_FUR_1	604	608	PF00082	0.424
CLV_PCSK_FUR_1	692	696	PF00082	0.590
CLV_PCSK_KEX2_1	123	125	PF00082	0.606
CLV_PCSK_KEX2_1	167	169	PF00082	0.528
CLV_PCSK_KEX2_1	254	256	PF00082	0.357
CLV_PCSK_KEX2_1	341	343	PF00082	0.594
CLV_PCSK_KEX2_1	497	499	PF00082	0.669
CLV_PCSK_KEX2_1	558	560	PF00082	0.545
CLV_PCSK_KEX2_1	603	605	PF00082	0.502
CLV_PCSK_KEX2_1	606	608	PF00082	0.507
CLV_PCSK_KEX2_1	624	626	PF00082	0.578
CLV_PCSK_KEX2_1	642	644	PF00082	0.653
CLV_PCSK_KEX2_1	692	694	PF00082	0.604
CLV_PCSK_PC1ET2_1	254	256	PF00082	0.357
CLV_PCSK_PC7_1	493	499	PF00082	0.538
CLV_PCSK_PC7_1	638	644	PF00082	0.509
CLV_PCSK_SKI1_1	170	174	PF00082	0.467
CLV_PCSK_SKI1_1	219	223	PF00082	0.580
CLV_PCSK_SKI1_1	227	231	PF00082	0.555
CLV_PCSK_SKI1_1	286	290	PF00082	0.447
CLV_PCSK_SKI1_1	305	309	PF00082	0.433
CLV_PCSK_SKI1_1	396	400	PF00082	0.373
CLV_PCSK_SKI1_1	488	492	PF00082	0.520
CLV_PCSK_SKI1_1	579	583	PF00082	0.457
CLV_PCSK_SKI1_1	595	599	PF00082	0.466
CLV_PCSK_SKI1_1	625	629	PF00082	0.627
DEG_APCC_DBOX_1	169	177	PF00400	0.451
DEG_APCC_DBOX_1	226	234	PF00400	0.594
DEG_Nend_UBRbox_2	1	3	PF02207	0.491
DEG_SPOP_SBC_1	519	523	PF00917	0.642
DOC_CYCLIN_RxL_1	224	232	PF00134	0.342
DOC_CYCLIN_RxL_1	573	586	PF00134	0.536
DOC_MAPK_gen_1	206	215	PF00069	0.405
DOC_MAPK_gen_1	61	69	PF00069	0.501
DOC_MAPK_MEF2A_6	316	324	PF00069	0.519
DOC_MAPK_MEF2A_6	63	71	PF00069	0.505
DOC_PP2B_LxvP_1	183	186	PF13499	0.494
DOC_PP2B_LxvP_1	336	339	PF13499	0.492
DOC_USP7_MATH_1	112	116	PF00917	0.520
DOC_USP7_MATH_1	32	36	PF00917	0.509
DOC_USP7_MATH_1	426	430	PF00917	0.604
DOC_USP7_MATH_1	608	612	PF00917	0.528
DOC_USP7_MATH_1	678	682	PF00917	0.530
DOC_USP7_UBL2_3	402	406	PF12436	0.358
DOC_WW_Pin1_4	13	18	PF00397	0.510
DOC_WW_Pin1_4	28	33	PF00397	0.549
DOC_WW_Pin1_4	373	378	PF00397	0.588
DOC_WW_Pin1_4	429	434	PF00397	0.557
DOC_WW_Pin1_4	685	690	PF00397	0.482
DOC_WW_Pin1_4	76	81	PF00397	0.514
DOC_WW_Pin1_4	84	89	PF00397	0.460
LIG_14-3-3_CanoR_1	212	216	PF00244	0.483
LIG_14-3-3_CanoR_1	219	229	PF00244	0.459
LIG_14-3-3_CanoR_1	290	299	PF00244	0.468
LIG_14-3-3_CanoR_1	353	363	PF00244	0.510
LIG_14-3-3_CanoR_1	39	45	PF00244	0.627
LIG_14-3-3_CanoR_1	46	53	PF00244	0.577
LIG_14-3-3_CanoR_1	573	582	PF00244	0.466
LIG_14-3-3_CanoR_1	624	628	PF00244	0.738
LIG_14-3-3_CanoR_1	632	636	PF00244	0.554
LIG_14-3-3_CanoR_1	682	689	PF00244	0.500
LIG_14-3-3_CanoR_1	70	78	PF00244	0.592
LIG_Actin_WH2_2	239	256	PF00022	0.352
LIG_Actin_WH2_2	382	398	PF00022	0.344
LIG_BRCT_BRCA1_1	26	30	PF00533	0.515
LIG_FAT_LD_1	385	393	PF03623	0.437
LIG_FHA_1	16	22	PF00498	0.521
LIG_FHA_1	326	332	PF00498	0.534
LIG_FHA_1	45	51	PF00498	0.588
LIG_FHA_1	490	496	PF00498	0.602
LIG_FHA_1	62	68	PF00498	0.514
LIG_FHA_2	189	195	PF00498	0.503
LIG_FHA_2	212	218	PF00498	0.446
LIG_FHA_2	271	277	PF00498	0.358
LIG_FHA_2	500	506	PF00498	0.529
LIG_FHA_2	611	617	PF00498	0.637
LIG_GBD_Chelix_1	165	173	PF00786	0.520
LIG_Integrin_RGD_1	614	616	PF01839	0.510
LIG_LIR_Gen_1	232	239	PF02991	0.332
LIG_LIR_Gen_1	437	445	PF02991	0.493
LIG_LIR_Gen_1	696	705	PF02991	0.592
LIG_LIR_Nem_3	115	120	PF02991	0.649
LIG_LIR_Nem_3	232	237	PF02991	0.335
LIG_LIR_Nem_3	437	442	PF02991	0.494
LIG_LIR_Nem_3	696	702	PF02991	0.585
LIG_NRBOX	308	314	PF00104	0.356
LIG_PCNA_yPIPBox_3	305	313	PF02747	0.355
LIG_Rb_pABgroove_1	228	236	PF01858	0.349
LIG_RPA_C_Fungi	554	566	PF08784	0.539
LIG_SH2_CRK	234	238	PF00017	0.324
LIG_SH2_NCK_1	234	238	PF00017	0.324
LIG_SH2_STAT5	199	202	PF00017	0.452
LIG_SH3_1	82	88	PF00018	0.489
LIG_SH3_2	85	90	PF14604	0.471
LIG_SH3_3	82	88	PF00018	0.492
LIG_SUMO_SIM_anti_2	247	254	PF11976	0.490
LIG_SUMO_SIM_par_1	228	235	PF11976	0.429
LIG_TRAF2_1	469	472	PF00917	0.425
LIG_TRFH_1	181	185	PF08558	0.485
MOD_CDC14_SPxK_1	79	82	PF00782	0.505
MOD_CDC14_SPxK_1	87	90	PF00782	0.444
MOD_CDK_SPxK_1	76	82	PF00069	0.504
MOD_CDK_SPxK_1	84	90	PF00069	0.455
MOD_CDK_SPxxK_3	685	692	PF00069	0.471
MOD_CK1_1	132	138	PF00069	0.534
MOD_CK1_1	220	226	PF00069	0.358
MOD_CK1_1	354	360	PF00069	0.534
MOD_CK1_1	370	376	PF00069	0.558
MOD_CK1_1	429	435	PF00069	0.606
MOD_CK1_1	44	50	PF00069	0.626
MOD_CK1_1	446	452	PF00069	0.478
MOD_CK1_1	520	526	PF00069	0.691
MOD_CK1_1	631	637	PF00069	0.494
MOD_CK1_1	681	687	PF00069	0.512
MOD_CK2_1	113	119	PF00069	0.707
MOD_CK2_1	135	141	PF00069	0.728
MOD_CK2_1	152	158	PF00069	0.455
MOD_CK2_1	172	178	PF00069	0.335
MOD_CK2_1	188	194	PF00069	0.471
MOD_CK2_1	19	25	PF00069	0.515
MOD_CK2_1	211	217	PF00069	0.482
MOD_CK2_1	270	276	PF00069	0.363
MOD_CK2_1	28	34	PF00069	0.487
MOD_CK2_1	466	472	PF00069	0.430
MOD_CK2_1	493	499	PF00069	0.644
MOD_CK2_1	572	578	PF00069	0.547
MOD_CK2_1	684	690	PF00069	0.483
MOD_Cter_Amidation	622	625	PF01082	0.637
MOD_GlcNHglycan	131	134	PF01048	0.673
MOD_GlcNHglycan	136	140	PF01048	0.697
MOD_GlcNHglycan	34	37	PF01048	0.677
MOD_GlcNHglycan	359	362	PF01048	0.591
MOD_GlcNHglycan	429	432	PF01048	0.615
MOD_GlcNHglycan	515	518	PF01048	0.623
MOD_GlcNHglycan	610	613	PF01048	0.615
MOD_GlcNHglycan	644	648	PF01048	0.594
MOD_GlcNHglycan	668	671	PF01048	0.653
MOD_GlcNHglycan	71	74	PF01048	0.578
MOD_GSK3_1	15	22	PF00069	0.521
MOD_GSK3_1	24	31	PF00069	0.584
MOD_GSK3_1	244	251	PF00069	0.354
MOD_GSK3_1	290	297	PF00069	0.434
MOD_GSK3_1	369	376	PF00069	0.685
MOD_GSK3_1	40	47	PF00069	0.580
MOD_GSK3_1	416	423	PF00069	0.375
MOD_GSK3_1	443	450	PF00069	0.477
MOD_GSK3_1	489	496	PF00069	0.543
MOD_GSK3_1	501	508	PF00069	0.524
MOD_GSK3_1	513	520	PF00069	0.787
MOD_GSK3_1	568	575	PF00069	0.550
MOD_GSK3_1	677	684	PF00069	0.545
MOD_GSK3_1	694	701	PF00069	0.440
MOD_GSK3_1	86	93	PF00069	0.471
MOD_N-GLC_1	583	588	PF02516	0.359
MOD_NEK2_1	113	118	PF00069	0.583
MOD_NEK2_1	172	177	PF00069	0.516
MOD_NEK2_1	229	234	PF00069	0.340
MOD_NEK2_1	24	29	PF00069	0.510
MOD_NEK2_1	269	274	PF00069	0.444
MOD_NEK2_1	320	325	PF00069	0.575
MOD_NEK2_1	416	421	PF00069	0.402
MOD_NEK2_1	5	10	PF00069	0.499
MOD_NEK2_1	512	517	PF00069	0.544
MOD_NEK2_1	518	523	PF00069	0.541
MOD_NEK2_1	71	76	PF00069	0.649
MOD_NEK2_2	623	628	PF00069	0.494
MOD_PIKK_1	300	306	PF00454	0.507
MOD_PIKK_1	375	381	PF00454	0.557
MOD_PIKK_1	505	511	PF00454	0.533
MOD_PIKK_1	568	574	PF00454	0.530
MOD_PK_1	63	69	PF00069	0.563
MOD_PK_1	694	700	PF00069	0.583
MOD_PKA_1	123	129	PF00069	0.682
MOD_PKA_1	290	296	PF00069	0.434
MOD_PKA_1	694	700	PF00069	0.583
MOD_PKA_2	123	129	PF00069	0.670
MOD_PKA_2	211	217	PF00069	0.487
MOD_PKA_2	38	44	PF00069	0.686
MOD_PKA_2	45	51	PF00069	0.579
MOD_PKA_2	572	578	PF00069	0.547
MOD_PKA_2	599	605	PF00069	0.478
MOD_PKA_2	623	629	PF00069	0.742
MOD_PKA_2	631	637	PF00069	0.550
MOD_PKA_2	666	672	PF00069	0.531
MOD_PKA_2	681	687	PF00069	0.583
MOD_PKA_2	69	75	PF00069	0.633
MOD_PKA_2	694	700	PF00069	0.485
MOD_PKB_1	61	69	PF00069	0.634
MOD_PKB_1	692	700	PF00069	0.588
MOD_Plk_1	179	185	PF00069	0.473
MOD_Plk_1	19	25	PF00069	0.515
MOD_Plk_1	201	207	PF00069	0.420
MOD_Plk_1	248	254	PF00069	0.467
MOD_Plk_1	48	54	PF00069	0.502
MOD_Plk_1	583	589	PF00069	0.357
MOD_Plk_1	643	649	PF00069	0.515
MOD_Plk_2-3	211	217	PF00069	0.525
MOD_Plk_2-3	235	241	PF00069	0.412
MOD_Plk_4	19	25	PF00069	0.635
MOD_Plk_4	248	254	PF00069	0.364
MOD_Plk_4	320	326	PF00069	0.429
MOD_Plk_4	694	700	PF00069	0.583
MOD_Plk_4	71	77	PF00069	0.492
MOD_ProDKin_1	13	19	PF00069	0.512
MOD_ProDKin_1	28	34	PF00069	0.550
MOD_ProDKin_1	373	379	PF00069	0.580
MOD_ProDKin_1	429	435	PF00069	0.559
MOD_ProDKin_1	685	691	PF00069	0.477
MOD_ProDKin_1	76	82	PF00069	0.516
MOD_ProDKin_1	84	90	PF00069	0.458
MOD_SUMO_for_1	106	109	PF00179	0.462
MOD_SUMO_for_1	284	287	PF00179	0.451
MOD_SUMO_for_1	295	298	PF00179	0.435
MOD_SUMO_rev_2	293	297	PF00179	0.400
MOD_SUMO_rev_2	575	582	PF00179	0.472
TRG_DiLeu_BaEn_4	178	184	PF01217	0.466
TRG_DiLeu_BaEn_4	317	323	PF01217	0.361
TRG_DiLeu_BaEn_4	471	477	PF01217	0.419
TRG_ENDOCYTIC_2	117	120	PF00928	0.657
TRG_ENDOCYTIC_2	234	237	PF00928	0.329
TRG_ER_diArg_1	167	170	PF00400	0.525
TRG_ER_diArg_1	456	459	PF00400	0.623
TRG_ER_diArg_1	558	560	PF00400	0.629
TRG_ER_diArg_1	592	595	PF00400	0.464
TRG_ER_diArg_1	603	606	PF00400	0.499
TRG_ER_diArg_1	641	643	PF00400	0.633
TRG_ER_diArg_1	691	694	PF00400	0.591
TRG_Pf-PMV_PEXEL_1	290	294	PF00026	0.402
TRG_Pf-PMV_PEXEL_1	311	315	PF00026	0.488
TRG_Pf-PMV_PEXEL_1	558	563	PF00026	0.544
TRG_Pf-PMV_PEXEL_1	579	583	PF00026	0.457
TRG_Pf-PMV_PEXEL_1	82	86	PF00026	0.497

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I9M3	Leptomonas seymouri	33%	93%
A0A3Q8IH40	Leishmania donovani	62%	97%
A4I491	Leishmania infantum	62%	97%
E9ADP7	Leishmania major	61%	100%
E9AM33	Leishmania mexicana (strain MHOM/GT/2001/U1103)	56%	100%