Sen15 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HH16_LEIBR

TriTrypDb:

LbrM.29.0090 , LBRM2903_290006200

Length:

113

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HH16

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HH16

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	56	60	PF00656	0.369
CLV_PCSK_KEX2_1	47	49	PF00082	0.294
CLV_PCSK_PC1ET2_1	47	49	PF00082	0.294
DEG_SPOP_SBC_1	35	39	PF00917	0.332
DOC_CYCLIN_yCln2_LP_2	51	57	PF00134	0.283
DOC_MAPK_gen_1	47	55	PF00069	0.279
DOC_MAPK_MEF2A_6	47	55	PF00069	0.279
DOC_PP2B_LxvP_1	51	54	PF13499	0.269
DOC_USP7_MATH_1	108	112	PF00917	0.580
DOC_USP7_MATH_1	35	39	PF00917	0.312
DOC_USP7_MATH_1	57	61	PF00917	0.357
DOC_WW_Pin1_4	1	6	PF00397	0.647
LIG_BIR_II_1	1	5	PF00653	0.474
LIG_deltaCOP1_diTrp_1	70	78	PF00928	0.447
LIG_FHA_1	21	27	PF00498	0.411
LIG_FHA_2	37	43	PF00498	0.432
LIG_LIR_Gen_1	22	33	PF02991	0.489
LIG_LIR_Gen_1	70	77	PF02991	0.447
LIG_LIR_Gen_1	8	19	PF02991	0.392
LIG_LIR_Nem_3	22	28	PF02991	0.452
LIG_LIR_Nem_3	70	74	PF02991	0.445
LIG_LIR_Nem_3	8	14	PF02991	0.380
LIG_LIR_Nem_3	88	93	PF02991	0.238
LIG_PDZ_Class_1	108	113	PF00595	0.444
LIG_Pex14_1	21	25	PF04695	0.362
LIG_PTB_Apo_2	28	35	PF02174	0.437
LIG_SH2_GRB2like	25	28	PF00017	0.314
LIG_SH2_SRC	11	14	PF00017	0.328
LIG_SH2_STAT5	25	28	PF00017	0.374
LIG_SH2_STAT5	50	53	PF00017	0.276
LIG_SUMO_SIM_anti_2	70	76	PF11976	0.389
MOD_GlcNHglycan	110	113	PF01048	0.451
MOD_GlcNHglycan	42	46	PF01048	0.521
MOD_GlcNHglycan	63	66	PF01048	0.427
MOD_GSK3_1	1	8	PF00069	0.522
MOD_GSK3_1	104	111	PF00069	0.393
MOD_GSK3_1	55	62	PF00069	0.612
MOD_NEK2_1	20	25	PF00069	0.435
MOD_NEK2_1	34	39	PF00069	0.221
MOD_NEK2_1	96	101	PF00069	0.450
MOD_PIKK_1	20	26	PF00454	0.377
MOD_Plk_1	85	91	PF00069	0.423
MOD_Plk_4	36	42	PF00069	0.269
MOD_Plk_4	98	104	PF00069	0.377
MOD_ProDKin_1	1	7	PF00069	0.632
TRG_DiLeu_BaEn_1	70	75	PF01217	0.389
TRG_ENDOCYTIC_2	11	14	PF00928	0.377
TRG_ENDOCYTIC_2	25	28	PF00928	0.462
TRG_ENDOCYTIC_2	50	53	PF00928	0.267
TRG_ER_diArg_1	14	17	PF00400	0.293

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I1F2	Leptomonas seymouri	41%	100%
A0A3Q8IEY1	Leishmania donovani	80%	91%
A4I445	Leishmania infantum	80%	91%
E9ADL0	Leishmania major	79%	100%
E9AM71	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	91%