FACT complex subunit

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

transcription factor-like protein

Species:

Leishmania braziliensis

UniProt:

A4HH10_LEIBR

TriTrypDb:

LbrM.29.0030 , LBRM2903_290005600

Length:

1048

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0008023	transcription elongation factor complex	3	12
GO:0032991	protein-containing complex	1	12
GO:0035101	FACT complex	4	12
GO:0140513	nuclear protein-containing complex	2	12

Expansion

Sequence features

A4HH10

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HH10

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	12
GO:0006259	DNA metabolic process	4	12
GO:0006260	DNA replication	5	12
GO:0006281	DNA repair	5	12
GO:0006725	cellular aromatic compound metabolic process	3	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0006950	response to stress	2	12
GO:0006974	DNA damage response	4	12
GO:0008152	metabolic process	1	12
GO:0009987	cellular process	1	12
GO:0033554	cellular response to stress	3	12
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0043170	macromolecule metabolic process	3	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0044260	obsolete cellular macromolecule metabolic process	3	12
GO:0046483	heterocycle metabolic process	3	12
GO:0050896	response to stimulus	1	12
GO:0051716	cellular response to stimulus	2	12
GO:0071704	organic substance metabolic process	2	12
GO:0090304	nucleic acid metabolic process	4	12
GO:1901360	organic cyclic compound metabolic process	3	12
GO:0006325	chromatin organization	4	1
GO:0006354	DNA-templated transcription elongation	6	1
GO:0006355	regulation of DNA-templated transcription	6	1
GO:0006357	regulation of transcription by RNA polymerase II	7	1
GO:0006368	transcription elongation by RNA polymerase II	7	1
GO:0009058	biosynthetic process	2	1
GO:0009059	macromolecule biosynthetic process	4	1
GO:0009889	regulation of biosynthetic process	4	1
GO:0009891	positive regulation of biosynthetic process	5	1
GO:0009893	positive regulation of metabolic process	4	1
GO:0010468	regulation of gene expression	5	1
GO:0010556	regulation of macromolecule biosynthetic process	5	1
GO:0010557	positive regulation of macromolecule biosynthetic process	6	1
GO:0010604	positive regulation of macromolecule metabolic process	5	1
GO:0016043	cellular component organization	3	1
GO:0016070	RNA metabolic process	5	1
GO:0018130	heterocycle biosynthetic process	4	1
GO:0019219	regulation of nucleobase-containing compound metabolic process	5	1
GO:0019222	regulation of metabolic process	3	1
GO:0019438	aromatic compound biosynthetic process	4	1
GO:0031323	regulation of cellular metabolic process	4	1
GO:0031325	positive regulation of cellular metabolic process	5	1
GO:0031326	regulation of cellular biosynthetic process	5	1
GO:0031328	positive regulation of cellular biosynthetic process	6	1
GO:0032774	RNA biosynthetic process	5	1
GO:0032784	regulation of DNA-templated transcription elongation	7	1
GO:0032786	positive regulation of DNA-templated transcription, elongation	8	1
GO:0032968	positive regulation of transcription elongation by RNA polymerase II	9	1
GO:0034243	regulation of transcription elongation by RNA polymerase II	8	1
GO:0034654	nucleobase-containing compound biosynthetic process	4	1
GO:0044249	cellular biosynthetic process	3	1
GO:0044271	cellular nitrogen compound biosynthetic process	4	1
GO:0045893	positive regulation of DNA-templated transcription	7	1
GO:0045935	positive regulation of nucleobase-containing compound metabolic process	6	1
GO:0045944	positive regulation of transcription by RNA polymerase II	8	1
GO:0048518	positive regulation of biological process	3	1
GO:0048522	positive regulation of cellular process	4	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0051171	regulation of nitrogen compound metabolic process	4	1
GO:0051173	positive regulation of nitrogen compound metabolic process	5	1
GO:0051252	regulation of RNA metabolic process	5	1
GO:0051254	positive regulation of RNA metabolic process	6	1
GO:0060255	regulation of macromolecule metabolic process	4	1
GO:0065007	biological regulation	1	1
GO:0071840	cellular component organization or biogenesis	2	1
GO:0080090	regulation of primary metabolic process	4	1
GO:1901362	organic cyclic compound biosynthetic process	4	1
GO:1901576	organic substance biosynthetic process	3	1
GO:1902680	positive regulation of RNA biosynthetic process	7	1
GO:1903506	regulation of nucleic acid-templated transcription	7	1
GO:1903508	positive regulation of nucleic acid-templated transcription	8	1
GO:2001141	regulation of RNA biosynthetic process	6	1

Molecular functions
Term	Name	Level	Count
GO:0003682	chromatin binding	2	1
GO:0005488	binding	1	1
GO:0031491	nucleosome binding	3	1
GO:0044877	protein-containing complex binding	2	1
GO:0003824	catalytic activity	1	3
GO:0004177	aminopeptidase activity	5	3
GO:0008233	peptidase activity	3	3
GO:0008238	exopeptidase activity	4	3
GO:0016787	hydrolase activity	2	3
GO:0140096	catalytic activity, acting on a protein	2	3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	931	935	PF00656	0.660
CLV_C14_Caspase3-7	967	971	PF00656	0.510
CLV_MEL_PAP_1	277	283	PF00089	0.373
CLV_NRD_NRD_1	1004	1006	PF00675	0.639
CLV_NRD_NRD_1	1046	1048	PF00675	0.574
CLV_NRD_NRD_1	148	150	PF00675	0.384
CLV_NRD_NRD_1	190	192	PF00675	0.223
CLV_NRD_NRD_1	425	427	PF00675	0.315
CLV_NRD_NRD_1	450	452	PF00675	0.492
CLV_NRD_NRD_1	629	631	PF00675	0.210
CLV_NRD_NRD_1	725	727	PF00675	0.407
CLV_NRD_NRD_1	749	751	PF00675	0.438
CLV_NRD_NRD_1	985	987	PF00675	0.510
CLV_PCSK_KEX2_1	1006	1008	PF00082	0.685
CLV_PCSK_KEX2_1	1046	1048	PF00082	0.597
CLV_PCSK_KEX2_1	148	150	PF00082	0.377
CLV_PCSK_KEX2_1	190	192	PF00082	0.278
CLV_PCSK_KEX2_1	450	452	PF00082	0.612
CLV_PCSK_KEX2_1	631	633	PF00082	0.208
CLV_PCSK_KEX2_1	749	751	PF00082	0.582
CLV_PCSK_KEX2_1	985	987	PF00082	0.531
CLV_PCSK_PC1ET2_1	1006	1008	PF00082	0.685
CLV_PCSK_PC1ET2_1	631	633	PF00082	0.301
CLV_PCSK_SKI1_1	213	217	PF00082	0.393
CLV_PCSK_SKI1_1	294	298	PF00082	0.373
CLV_PCSK_SKI1_1	388	392	PF00082	0.326
CLV_PCSK_SKI1_1	478	482	PF00082	0.336
CLV_PCSK_SKI1_1	594	598	PF00082	0.188
CLV_PCSK_SKI1_1	606	610	PF00082	0.223
CLV_PCSK_SKI1_1	631	635	PF00082	0.278
CLV_PCSK_SKI1_1	78	82	PF00082	0.267
CLV_PCSK_SKI1_1	803	807	PF00082	0.355
CLV_PCSK_SKI1_1	812	816	PF00082	0.206
CLV_Separin_Metazoa	145	149	PF03568	0.341
DEG_APCC_DBOX_1	387	395	PF00400	0.226
DEG_APCC_DBOX_1	449	457	PF00400	0.489
DEG_APCC_DBOX_1	477	485	PF00400	0.472
DEG_APCC_DBOX_1	510	518	PF00400	0.357
DEG_APCC_DBOX_1	811	819	PF00400	0.257
DEG_APCC_DBOX_1	866	874	PF00400	0.419
DEG_Nend_UBRbox_3	1	3	PF02207	0.519
DEG_SCF_FBW7_1	818	825	PF00400	0.501
DEG_SCF_SKP2-CKS1_1	514	521	PF00560	0.385
DEG_SPOP_SBC_1	497	501	PF00917	0.373
DOC_CDC14_PxL_1	157	165	PF14671	0.426
DOC_CKS1_1	47	52	PF01111	0.407
DOC_CYCLIN_RxL_1	291	300	PF00134	0.373
DOC_CYCLIN_yCln2_LP_2	718	724	PF00134	0.410
DOC_MAPK_DCC_7	641	651	PF00069	0.461
DOC_MAPK_gen_1	541	548	PF00069	0.506
DOC_MAPK_gen_1	589	597	PF00069	0.344
DOC_MAPK_gen_1	726	734	PF00069	0.321
DOC_MAPK_HePTP_8	850	862	PF00069	0.436
DOC_MAPK_MEF2A_6	1024	1032	PF00069	0.589
DOC_MAPK_MEF2A_6	541	548	PF00069	0.479
DOC_MAPK_MEF2A_6	571	578	PF00069	0.501
DOC_MAPK_MEF2A_6	853	862	PF00069	0.421
DOC_PP1_RVXF_1	539	546	PF00149	0.396
DOC_PP1_RVXF_1	697	704	PF00149	0.278
DOC_PP1_RVXF_1	810	817	PF00149	0.240
DOC_PP2B_LxvP_1	323	326	PF13499	0.270
DOC_PP2B_LxvP_1	649	652	PF13499	0.419
DOC_PP2B_PxIxI_1	857	863	PF00149	0.501
DOC_PP4_FxxP_1	536	539	PF00568	0.346
DOC_SPAK_OSR1_1	280	284	PF12202	0.270
DOC_USP7_MATH_1	152	156	PF00917	0.334
DOC_USP7_MATH_1	228	232	PF00917	0.375
DOC_USP7_MATH_1	367	371	PF00917	0.384
DOC_USP7_MATH_1	633	637	PF00917	0.454
DOC_USP7_MATH_1	706	710	PF00917	0.347
DOC_USP7_MATH_1	748	752	PF00917	0.541
DOC_USP7_MATH_1	866	870	PF00917	0.419
DOC_USP7_UBL2_3	203	207	PF12436	0.282
DOC_USP7_UBL2_3	423	427	PF12436	0.318
DOC_USP7_UBL2_3	594	598	PF12436	0.396
DOC_USP7_UBL2_3	853	857	PF12436	0.419
DOC_WD40_RPTOR_TOS_1	403	409	PF00400	0.226
DOC_WW_Pin1_4	46	51	PF00397	0.391
DOC_WW_Pin1_4	515	520	PF00397	0.423
DOC_WW_Pin1_4	601	606	PF00397	0.346
DOC_WW_Pin1_4	642	647	PF00397	0.436
DOC_WW_Pin1_4	818	823	PF00397	0.489
LIG_14-3-3_CanoR_1	13	21	PF00244	0.457
LIG_14-3-3_CanoR_1	329	337	PF00244	0.339
LIG_14-3-3_CanoR_1	368	378	PF00244	0.317
LIG_14-3-3_CanoR_1	458	467	PF00244	0.490
LIG_14-3-3_CanoR_1	478	488	PF00244	0.228
LIG_14-3-3_CanoR_1	511	515	PF00244	0.446
LIG_14-3-3_CanoR_1	632	642	PF00244	0.406
LIG_14-3-3_CanoR_1	682	686	PF00244	0.451
LIG_14-3-3_CanoR_1	726	735	PF00244	0.249
LIG_14-3-3_CanoR_1	749	753	PF00244	0.441
LIG_14-3-3_CanoR_1	803	809	PF00244	0.453
LIG_14-3-3_CanoR_1	867	871	PF00244	0.367
LIG_14-3-3_CanoR_1	894	898	PF00244	0.521
LIG_Actin_WH2_2	667	684	PF00022	0.406
LIG_APCC_ABBA_1	270	275	PF00400	0.373
LIG_BRCT_BRCA1_1	352	356	PF00533	0.276
LIG_CaM_IQ_9	616	632	PF13499	0.461
LIG_Clathr_ClatBox_1	362	366	PF01394	0.226
LIG_CSL_BTD_1	544	547	PF09270	0.461
LIG_CtBP_PxDLS_1	1029	1033	PF00389	0.686
LIG_deltaCOP1_diTrp_1	36	42	PF00928	0.207
LIG_deltaCOP1_diTrp_1	902	909	PF00928	0.381
LIG_EH1_1	209	217	PF00400	0.373
LIG_EH1_1	845	853	PF00400	0.501
LIG_EVH1_2	244	248	PF00568	0.373
LIG_FHA_1	100	106	PF00498	0.491
LIG_FHA_1	1008	1014	PF00498	0.529
LIG_FHA_1	115	121	PF00498	0.368
LIG_FHA_1	293	299	PF00498	0.297
LIG_FHA_1	358	364	PF00498	0.298
LIG_FHA_1	400	406	PF00498	0.352
LIG_FHA_1	408	414	PF00498	0.279
LIG_FHA_1	462	468	PF00498	0.613
LIG_FHA_1	504	510	PF00498	0.282
LIG_FHA_1	651	657	PF00498	0.524
LIG_FHA_1	70	76	PF00498	0.451
LIG_FHA_1	717	723	PF00498	0.397
LIG_FHA_1	79	85	PF00498	0.432
LIG_FHA_1	823	829	PF00498	0.406
LIG_FHA_1	93	99	PF00498	0.498
LIG_FHA_2	140	146	PF00498	0.216
LIG_FHA_2	206	212	PF00498	0.398
LIG_FHA_2	216	222	PF00498	0.411
LIG_FHA_2	261	267	PF00498	0.156
LIG_FHA_2	497	503	PF00498	0.434
LIG_FHA_2	894	900	PF00498	0.411
LIG_FHA_2	920	926	PF00498	0.657
LIG_FHA_2	938	944	PF00498	0.485
LIG_FHA_2	94	100	PF00498	0.596
LIG_GBD_Chelix_1	424	432	PF00786	0.364
LIG_Integrin_isoDGR_2	639	641	PF01839	0.228
LIG_LIR_Apic_2	599	605	PF02991	0.363
LIG_LIR_Apic_2	854	858	PF02991	0.419
LIG_LIR_Gen_1	141	151	PF02991	0.329
LIG_LIR_Gen_1	235	245	PF02991	0.376
LIG_LIR_Gen_1	36	42	PF02991	0.348
LIG_LIR_Gen_1	430	441	PF02991	0.521
LIG_LIR_Gen_1	575	586	PF02991	0.396
LIG_LIR_Gen_1	692	703	PF02991	0.276
LIG_LIR_Gen_1	835	844	PF02991	0.470
LIG_LIR_Gen_1	913	921	PF02991	0.491
LIG_LIR_Gen_1	979	988	PF02991	0.494
LIG_LIR_Nem_3	141	146	PF02991	0.326
LIG_LIR_Nem_3	235	240	PF02991	0.384
LIG_LIR_Nem_3	331	337	PF02991	0.262
LIG_LIR_Nem_3	36	41	PF02991	0.322
LIG_LIR_Nem_3	430	436	PF02991	0.453
LIG_LIR_Nem_3	501	507	PF02991	0.422
LIG_LIR_Nem_3	692	698	PF02991	0.285
LIG_LIR_Nem_3	709	714	PF02991	0.285
LIG_LIR_Nem_3	796	800	PF02991	0.366
LIG_LIR_Nem_3	835	839	PF02991	0.451
LIG_LIR_Nem_3	913	918	PF02991	0.440
LIG_LIR_Nem_3	979	983	PF02991	0.569
LIG_MYND_3	526	530	PF01753	0.370
LIG_NRBOX	162	168	PF00104	0.345
LIG_NRBOX	319	325	PF00104	0.253
LIG_NRBOX	476	482	PF00104	0.345
LIG_PCNA_yPIPBox_3	345	354	PF02747	0.335
LIG_Pex14_1	38	42	PF04695	0.411
LIG_Pex14_2	139	143	PF04695	0.424
LIG_PTB_Apo_2	282	289	PF02174	0.239
LIG_PTB_Phospho_1	282	288	PF10480	0.239
LIG_REV1ctd_RIR_1	289	298	PF16727	0.373
LIG_RPA_C_Fungi	8	20	PF08784	0.325
LIG_SH2_CRK	334	338	PF00017	0.279
LIG_SH2_CRK	602	606	PF00017	0.202
LIG_SH2_CRK	855	859	PF00017	0.257
LIG_SH2_STAP1	288	292	PF00017	0.239
LIG_SH2_STAP1	7	11	PF00017	0.311
LIG_SH2_STAT3	253	256	PF00017	0.239
LIG_SH2_STAT5	217	220	PF00017	0.156
LIG_SH2_STAT5	288	291	PF00017	0.230
LIG_SH2_STAT5	572	575	PF00017	0.266
LIG_SH2_STAT5	61	64	PF00017	0.316
LIG_SH2_STAT5	711	714	PF00017	0.411
LIG_SH3_2	1022	1027	PF14604	0.479
LIG_SH3_3	1019	1025	PF00018	0.547
LIG_SH3_3	1038	1044	PF00018	0.510
LIG_SH3_3	122	128	PF00018	0.513
LIG_SH3_3	44	50	PF00018	0.407
LIG_SH3_3	516	522	PF00018	0.489
LIG_SH3_3	541	547	PF00018	0.202
LIG_SH3_3	88	94	PF00018	0.465
LIG_SUMO_SIM_anti_2	102	107	PF11976	0.472
LIG_SUMO_SIM_anti_2	275	280	PF11976	0.240
LIG_SUMO_SIM_anti_2	359	366	PF11976	0.208
LIG_SUMO_SIM_anti_2	79	84	PF11976	0.326
LIG_SUMO_SIM_anti_2	830	835	PF11976	0.258
LIG_SUMO_SIM_par_1	101	107	PF11976	0.428
LIG_SUMO_SIM_par_1	294	300	PF11976	0.257
LIG_SUMO_SIM_par_1	359	366	PF11976	0.299
LIG_SUMO_SIM_par_1	462	468	PF11976	0.606
LIG_SUMO_SIM_par_1	858	864	PF11976	0.373
LIG_SxIP_EBH_1	1021	1035	PF03271	0.474
LIG_TRAF2_1	133	136	PF00917	0.349
LIG_TRAF2_1	500	503	PF00917	0.450
LIG_TRAF2_1	580	583	PF00917	0.226
LIG_TRAF2_1	779	782	PF00917	0.458
LIG_TRAF2_1	827	830	PF00917	0.156
LIG_TRAF2_1	922	925	PF00917	0.471
LIG_TYR_ITIM	431	436	PF00017	0.522
LIG_UBA3_1	58	66	PF00899	0.380
LIG_UBA3_1	694	699	PF00899	0.438
LIG_WRC_WIRS_1	348	353	PF05994	0.398
LIG_WRC_WIRS_1	773	778	PF05994	0.456
LIG_WRC_WIRS_1	805	810	PF05994	0.245
LIG_WRC_WIRS_1	833	838	PF05994	0.373
MOD_CDK_SPK_2	601	606	PF00069	0.156
MOD_CDK_SPxK_1	515	521	PF00069	0.388
MOD_CK1_1	12	18	PF00069	0.413
MOD_CK1_1	155	161	PF00069	0.262
MOD_CK1_1	350	356	PF00069	0.288
MOD_CK1_1	393	399	PF00069	0.311
MOD_CK1_1	46	52	PF00069	0.515
MOD_CK1_1	804	810	PF00069	0.275
MOD_CK1_1	937	943	PF00069	0.583
MOD_CK1_1	949	955	PF00069	0.594
MOD_CK1_1	969	975	PF00069	0.616
MOD_CK1_1	976	982	PF00069	0.482
MOD_CK1_1	994	1000	PF00069	0.544
MOD_CK2_1	139	145	PF00069	0.216
MOD_CK2_1	215	221	PF00069	0.271
MOD_CK2_1	260	266	PF00069	0.277
MOD_CK2_1	367	373	PF00069	0.238
MOD_CK2_1	496	502	PF00069	0.530
MOD_CK2_1	510	516	PF00069	0.450
MOD_CK2_1	577	583	PF00069	0.167
MOD_CK2_1	824	830	PF00069	0.326
MOD_CK2_1	893	899	PF00069	0.475
MOD_CK2_1	919	925	PF00069	0.605
MOD_CK2_1	93	99	PF00069	0.490
MOD_CK2_1	937	943	PF00069	0.480
MOD_CK2_1	953	959	PF00069	0.589
MOD_CK2_1	960	966	PF00069	0.583
MOD_CK2_1	976	982	PF00069	0.606
MOD_CMANNOS	906	909	PF00535	0.361
MOD_Cter_Amidation	492	495	PF01082	0.438
MOD_GlcNHglycan	14	17	PF01048	0.360
MOD_GlcNHglycan	157	160	PF01048	0.311
MOD_GlcNHglycan	299	302	PF01048	0.380
MOD_GlcNHglycan	395	398	PF01048	0.337
MOD_GlcNHglycan	635	638	PF01048	0.290
MOD_GlcNHglycan	746	749	PF01048	0.600
MOD_GlcNHglycan	878	881	PF01048	0.373
MOD_GlcNHglycan	9	12	PF01048	0.342
MOD_GlcNHglycan	973	978	PF01048	0.571
MOD_GlcNHglycan	993	996	PF01048	0.415
MOD_GSK3_1	1	8	PF00069	0.512
MOD_GSK3_1	377	384	PF00069	0.275
MOD_GSK3_1	436	443	PF00069	0.553
MOD_GSK3_1	461	468	PF00069	0.633
MOD_GSK3_1	660	667	PF00069	0.156
MOD_GSK3_1	739	746	PF00069	0.446
MOD_GSK3_1	74	81	PF00069	0.354
MOD_GSK3_1	781	788	PF00069	0.390
MOD_GSK3_1	789	796	PF00069	0.422
MOD_GSK3_1	818	825	PF00069	0.322
MOD_GSK3_1	842	849	PF00069	0.315
MOD_GSK3_1	932	939	PF00069	0.599
MOD_GSK3_1	949	956	PF00069	0.532
MOD_GSK3_1	960	967	PF00069	0.524
MOD_GSK3_1	969	976	PF00069	0.587
MOD_LATS_1	801	807	PF00433	0.378
MOD_N-GLC_1	590	595	PF02516	0.167
MOD_N-GLC_1	919	924	PF02516	0.642
MOD_NEK2_1	1	6	PF00069	0.456
MOD_NEK2_1	139	144	PF00069	0.287
MOD_NEK2_1	215	220	PF00069	0.212
MOD_NEK2_1	292	297	PF00069	0.329
MOD_NEK2_1	356	361	PF00069	0.295
MOD_NEK2_1	407	412	PF00069	0.298
MOD_NEK2_1	436	441	PF00069	0.557
MOD_NEK2_1	555	560	PF00069	0.226
MOD_NEK2_1	590	595	PF00069	0.178
MOD_NEK2_1	600	605	PF00069	0.271
MOD_NEK2_1	681	686	PF00069	0.295
MOD_NEK2_1	744	749	PF00069	0.419
MOD_NEK2_1	824	829	PF00069	0.287
MOD_NEK2_1	846	851	PF00069	0.282
MOD_NEK2_1	885	890	PF00069	0.332
MOD_NEK2_2	706	711	PF00069	0.348
MOD_NEK2_2	893	898	PF00069	0.512
MOD_PIKK_1	252	258	PF00454	0.373
MOD_PIKK_1	785	791	PF00454	0.371
MOD_PIKK_1	822	828	PF00454	0.257
MOD_PKA_2	1023	1029	PF00069	0.684
MOD_PKA_2	12	18	PF00069	0.388
MOD_PKA_2	249	255	PF00069	0.167
MOD_PKA_2	328	334	PF00069	0.359
MOD_PKA_2	367	373	PF00069	0.202
MOD_PKA_2	510	516	PF00069	0.443
MOD_PKA_2	640	646	PF00069	0.373
MOD_PKA_2	664	670	PF00069	0.221
MOD_PKA_2	681	687	PF00069	0.293
MOD_PKA_2	725	731	PF00069	0.285
MOD_PKA_2	748	754	PF00069	0.436
MOD_PKA_2	766	772	PF00069	0.291
MOD_PKA_2	866	872	PF00069	0.257
MOD_PKA_2	893	899	PF00069	0.516
MOD_PKA_2	991	997	PF00069	0.554
MOD_PKB_1	1005	1013	PF00069	0.612
MOD_PKB_1	630	638	PF00069	0.282
MOD_Plk_1	121	127	PF00069	0.320
MOD_Plk_1	260	266	PF00069	0.270
MOD_Plk_1	43	49	PF00069	0.393
MOD_Plk_1	598	604	PF00069	0.153
MOD_Plk_1	78	84	PF00069	0.418
MOD_Plk_1	846	852	PF00069	0.282
MOD_Plk_1	885	891	PF00069	0.315
MOD_Plk_1	937	943	PF00069	0.596
MOD_Plk_1	952	958	PF00069	0.537
MOD_Plk_2-3	205	211	PF00069	0.282
MOD_Plk_2-3	260	266	PF00069	0.156
MOD_Plk_2-3	503	509	PF00069	0.384
MOD_Plk_2-3	832	838	PF00069	0.239
MOD_Plk_2-3	947	953	PF00069	0.638
MOD_Plk_2-3	960	966	PF00069	0.567
MOD_Plk_2-3	99	105	PF00069	0.437
MOD_Plk_4	152	158	PF00069	0.497
MOD_Plk_4	205	211	PF00069	0.373
MOD_Plk_4	347	353	PF00069	0.413
MOD_Plk_4	381	387	PF00069	0.309
MOD_Plk_4	407	413	PF00069	0.373
MOD_Plk_4	461	467	PF00069	0.584
MOD_Plk_4	572	578	PF00069	0.253
MOD_Plk_4	706	712	PF00069	0.415
MOD_Plk_4	78	84	PF00069	0.382
MOD_Plk_4	846	852	PF00069	0.282
MOD_Plk_4	937	943	PF00069	0.616
MOD_Plk_4	953	959	PF00069	0.488
MOD_ProDKin_1	46	52	PF00069	0.387
MOD_ProDKin_1	515	521	PF00069	0.432
MOD_ProDKin_1	601	607	PF00069	0.156
MOD_ProDKin_1	642	648	PF00069	0.282
MOD_ProDKin_1	818	824	PF00069	0.356
MOD_SUMO_for_1	623	626	PF00179	0.373
MOD_SUMO_rev_2	199	209	PF00179	0.256
TRG_DiLeu_BaEn_1	476	481	PF01217	0.373
TRG_DiLeu_BaEn_2	346	352	PF01217	0.156
TRG_ENDOCYTIC_2	217	220	PF00928	0.373
TRG_ENDOCYTIC_2	288	291	PF00928	0.239
TRG_ENDOCYTIC_2	334	337	PF00928	0.279
TRG_ENDOCYTIC_2	433	436	PF00928	0.554
TRG_ER_diArg_1	1004	1007	PF00400	0.623
TRG_ER_diArg_1	1046	1048	PF00400	0.600
TRG_ER_diArg_1	147	149	PF00400	0.381
TRG_ER_diArg_1	189	191	PF00400	0.235
TRG_ER_diArg_1	764	767	PF00400	0.410
TRG_NLS_MonoCore_2	1005	1010	PF00514	0.589
TRG_NLS_MonoExtC_3	1004	1009	PF00514	0.615
TRG_NLS_MonoExtN_4	1004	1010	PF00514	0.598
TRG_Pf-PMV_PEXEL_1	118	122	PF00026	0.452
TRG_Pf-PMV_PEXEL_1	294	299	PF00026	0.174
TRG_Pf-PMV_PEXEL_1	426	430	PF00026	0.355
TRG_Pf-PMV_PEXEL_1	478	483	PF00026	0.360

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IHS5	Leptomonas seymouri	74%	100%
A0A0S4JAR0	Bodo saltans	38%	100%
A0A1X0NZD4	Trypanosomatidae	53%	100%
A0A3S7X235	Leishmania donovani	84%	100%
A0A422NUY4	Trypanosoma rangeli	52%	100%
A4I439	Leishmania infantum	84%	100%
C9ZKS3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	53%	100%
E9ADK4	Leishmania major	84%	100%
E9AM77	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%
O82491	Arabidopsis thaliana	26%	98%
O94267	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	25%	100%
P0CQ22	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	28%	100%
P0CQ23	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	28%	100%
P32558	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	24%	100%
Q2UBF1	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	27%	100%
Q4HYB8	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	24%	100%
Q4P2U5	Ustilago maydis (strain 521 / FGSC 9021)	24%	100%
Q4WJ02	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	26%	100%
Q54S43	Dictyostelium discoideum	24%	98%
Q5A1D5	Candida albicans (strain SC5314 / ATCC MYA-2876)	24%	99%
Q5B2X8	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	26%	100%
Q61E63	Caenorhabditis briggsae	26%	100%
Q6BXE5	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	25%	100%
Q6C931	Yarrowia lipolytica (strain CLIB 122 / E 150)	28%	100%
Q6FWT4	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	24%	100%
Q756A7	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	25%	100%
Q7X923	Oryza sativa subsp. japonica	27%	99%
Q8H6B1	Zea mays	27%	99%
Q8IRG6	Drosophila melanogaster	25%	97%
Q8X0X6	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	24%	100%
Q920B9	Mus musculus	28%	100%
Q9N5R9	Caenorhabditis elegans	27%	100%
Q9W603	Xenopus laevis	27%	100%
Q9Y5B9	Homo sapiens	28%	100%
V5DLC1	Trypanosoma cruzi	51%	100%