Endonuclease/exonuclease/phosphatase-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

endonuclease/exonuclease/phosphatase-like protein

Species:

Leishmania braziliensis

UniProt:

A4HH07_LEIBR

TriTrypDb:

LbrM.28.3260 , LBRM2903_280015200

Length:

1100

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4HH07

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HH07

Function

Biological processes
Term	Name	Level	Count
GO:0007623	circadian rhythm	2	7
GO:0010468	regulation of gene expression	5	7
GO:0019222	regulation of metabolic process	3	7
GO:0032501	multicellular organismal process	1	7
GO:0032922	circadian regulation of gene expression	2	7
GO:0048511	rhythmic process	1	7
GO:0050789	regulation of biological process	2	7
GO:0060255	regulation of macromolecule metabolic process	4	7
GO:0065007	biological regulation	1	7

Molecular functions
Term	Name	Level	Count
GO:0000175	3'-5'-RNA exonuclease activity	7	7
GO:0003824	catalytic activity	1	7
GO:0004518	nuclease activity	4	7
GO:0004519	endonuclease activity	5	7
GO:0004527	exonuclease activity	5	7
GO:0004532	RNA exonuclease activity	5	7
GO:0004535	poly(A)-specific ribonuclease activity	8	7
GO:0004540	RNA nuclease activity	4	7
GO:0008408	3'-5' exonuclease activity	6	7
GO:0016787	hydrolase activity	2	7
GO:0016788	hydrolase activity, acting on ester bonds	3	7
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	6	7
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	6	7
GO:0140098	catalytic activity, acting on RNA	3	7
GO:0140640	catalytic activity, acting on a nucleic acid	2	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	406	410	PF00656	0.542
CLV_C14_Caspase3-7	508	512	PF00656	0.599
CLV_C14_Caspase3-7	892	896	PF00656	0.599
CLV_C14_Caspase3-7	9	13	PF00656	0.497
CLV_NRD_NRD_1	103	105	PF00675	0.598
CLV_NRD_NRD_1	228	230	PF00675	0.597
CLV_NRD_NRD_1	369	371	PF00675	0.733
CLV_NRD_NRD_1	397	399	PF00675	0.584
CLV_NRD_NRD_1	45	47	PF00675	0.567
CLV_NRD_NRD_1	501	503	PF00675	0.528
CLV_NRD_NRD_1	567	569	PF00675	0.758
CLV_NRD_NRD_1	633	635	PF00675	0.801
CLV_NRD_NRD_1	649	651	PF00675	0.565
CLV_NRD_NRD_1	70	72	PF00675	0.802
CLV_NRD_NRD_1	775	777	PF00675	0.699
CLV_NRD_NRD_1	883	885	PF00675	0.802
CLV_PCSK_FUR_1	187	191	PF00082	0.688
CLV_PCSK_FUR_1	935	939	PF00082	0.826
CLV_PCSK_KEX2_1	103	105	PF00082	0.558
CLV_PCSK_KEX2_1	130	132	PF00082	0.808
CLV_PCSK_KEX2_1	189	191	PF00082	0.686
CLV_PCSK_KEX2_1	228	230	PF00082	0.575
CLV_PCSK_KEX2_1	262	264	PF00082	0.621
CLV_PCSK_KEX2_1	369	371	PF00082	0.664
CLV_PCSK_KEX2_1	397	399	PF00082	0.584
CLV_PCSK_KEX2_1	501	503	PF00082	0.528
CLV_PCSK_KEX2_1	567	569	PF00082	0.754
CLV_PCSK_KEX2_1	606	608	PF00082	0.764
CLV_PCSK_KEX2_1	633	635	PF00082	0.801
CLV_PCSK_KEX2_1	70	72	PF00082	0.803
CLV_PCSK_KEX2_1	774	776	PF00082	0.702
CLV_PCSK_KEX2_1	882	884	PF00082	0.813
CLV_PCSK_KEX2_1	937	939	PF00082	0.830
CLV_PCSK_PC1ET2_1	130	132	PF00082	0.808
CLV_PCSK_PC1ET2_1	189	191	PF00082	0.686
CLV_PCSK_PC1ET2_1	262	264	PF00082	0.621
CLV_PCSK_PC1ET2_1	606	608	PF00082	0.811
CLV_PCSK_PC1ET2_1	882	884	PF00082	0.813
CLV_PCSK_PC1ET2_1	937	939	PF00082	0.852
CLV_PCSK_PC7_1	365	371	PF00082	0.807
CLV_PCSK_PC7_1	933	939	PF00082	0.849
CLV_PCSK_SKI1_1	262	266	PF00082	0.566
CLV_PCSK_SKI1_1	501	505	PF00082	0.529
CLV_PCSK_SKI1_1	567	571	PF00082	0.853
CLV_PCSK_SKI1_1	662	666	PF00082	0.576
CLV_PCSK_SKI1_1	706	710	PF00082	0.546
DEG_Nend_UBRbox_2	1	3	PF02207	0.558
DEG_SCF_FBW7_1	11	18	PF00400	0.520
DEG_SCF_TRCP1_1	416	421	PF00400	0.510
DEG_SPOP_SBC_1	644	648	PF00917	0.604
DEG_SPOP_SBC_1	77	81	PF00917	0.566
DEG_SPOP_SBC_1	982	986	PF00917	0.526
DOC_CDC14_PxL_1	247	255	PF14671	0.292
DOC_CDC14_PxL_1	484	492	PF14671	0.449
DOC_CDC14_PxL_1	991	999	PF14671	0.744
DOC_CKS1_1	359	364	PF01111	0.804
DOC_CKS1_1	382	387	PF01111	0.694
DOC_CKS1_1	391	396	PF01111	0.707
DOC_CKS1_1	600	605	PF01111	0.803
DOC_CKS1_1	684	689	PF01111	0.773
DOC_CKS1_1	926	931	PF01111	0.789
DOC_CYCLIN_yCln2_LP_2	382	388	PF00134	0.711
DOC_CYCLIN_yCln2_LP_2	490	496	PF00134	0.484
DOC_MAPK_DCC_7	245	254	PF00069	0.463
DOC_MAPK_DCC_7	606	616	PF00069	0.537
DOC_MAPK_gen_1	103	114	PF00069	0.530
DOC_MAPK_gen_1	240	249	PF00069	0.483
DOC_MAPK_gen_1	266	274	PF00069	0.404
DOC_MAPK_gen_1	329	337	PF00069	0.633
DOC_MAPK_MEF2A_6	245	254	PF00069	0.463
DOC_MAPK_MEF2A_6	820	828	PF00069	0.824
DOC_PP2B_LxvP_1	388	391	PF13499	0.599
DOC_PP4_FxxP_1	38	41	PF00568	0.806
DOC_PP4_FxxP_1	828	831	PF00568	0.557
DOC_SPAK_OSR1_1	243	247	PF12202	0.331
DOC_USP7_MATH_1	41	45	PF00917	0.717
DOC_USP7_MATH_1	414	418	PF00917	0.707
DOC_USP7_MATH_1	441	445	PF00917	0.662
DOC_USP7_MATH_1	547	551	PF00917	0.739
DOC_USP7_MATH_1	554	558	PF00917	0.711
DOC_USP7_MATH_1	643	647	PF00917	0.749
DOC_USP7_MATH_1	674	678	PF00917	0.558
DOC_USP7_MATH_1	729	733	PF00917	0.823
DOC_USP7_MATH_1	77	81	PF00917	0.757
DOC_USP7_MATH_1	857	861	PF00917	0.824
DOC_USP7_MATH_1	919	923	PF00917	0.642
DOC_USP7_MATH_1	99	103	PF00917	0.766
DOC_WW_Pin1_4	1001	1006	PF00397	0.654
DOC_WW_Pin1_4	11	16	PF00397	0.703
DOC_WW_Pin1_4	121	126	PF00397	0.727
DOC_WW_Pin1_4	28	33	PF00397	0.693
DOC_WW_Pin1_4	358	363	PF00397	0.696
DOC_WW_Pin1_4	381	386	PF00397	0.695
DOC_WW_Pin1_4	390	395	PF00397	0.706
DOC_WW_Pin1_4	489	494	PF00397	0.591
DOC_WW_Pin1_4	541	546	PF00397	0.723
DOC_WW_Pin1_4	550	555	PF00397	0.678
DOC_WW_Pin1_4	557	562	PF00397	0.672
DOC_WW_Pin1_4	569	574	PF00397	0.738
DOC_WW_Pin1_4	599	604	PF00397	0.810
DOC_WW_Pin1_4	670	675	PF00397	0.751
DOC_WW_Pin1_4	683	688	PF00397	0.714
DOC_WW_Pin1_4	693	698	PF00397	0.606
DOC_WW_Pin1_4	700	705	PF00397	0.685
DOC_WW_Pin1_4	723	728	PF00397	0.708
DOC_WW_Pin1_4	742	747	PF00397	0.667
DOC_WW_Pin1_4	775	780	PF00397	0.519
DOC_WW_Pin1_4	839	844	PF00397	0.773
DOC_WW_Pin1_4	855	860	PF00397	0.831
DOC_WW_Pin1_4	925	930	PF00397	0.823
DOC_WW_Pin1_4	941	946	PF00397	0.591
DOC_WW_Pin1_4	951	956	PF00397	0.713
DOC_WW_Pin1_4	963	968	PF00397	0.696
DOC_WW_Pin1_4	983	988	PF00397	0.657
LIG_14-3-3_CanoR_1	1021	1029	PF00244	0.487
LIG_14-3-3_CanoR_1	1032	1038	PF00244	0.600
LIG_14-3-3_CanoR_1	116	125	PF00244	0.626
LIG_14-3-3_CanoR_1	190	199	PF00244	0.708
LIG_14-3-3_CanoR_1	397	402	PF00244	0.735
LIG_14-3-3_CanoR_1	405	413	PF00244	0.561
LIG_14-3-3_CanoR_1	434	439	PF00244	0.749
LIG_14-3-3_CanoR_1	46	53	PF00244	0.787
LIG_14-3-3_CanoR_1	567	575	PF00244	0.706
LIG_14-3-3_CanoR_1	615	621	PF00244	0.765
LIG_14-3-3_CanoR_1	733	741	PF00244	0.780
LIG_Actin_WH2_2	306	323	PF00022	0.295
LIG_BIR_III_4	869	873	PF00653	0.561
LIG_BIR_III_4	895	899	PF00653	0.552
LIG_BRCT_BRCA1_1	176	180	PF00533	0.548
LIG_BRCT_BRCA1_1	235	239	PF00533	0.323
LIG_BRCT_BRCA1_1	419	423	PF00533	0.779
LIG_BRCT_BRCA1_1	824	828	PF00533	0.676
LIG_CtBP_PxDLS_1	908	914	PF00389	0.555
LIG_EVH1_2	34	38	PF00568	0.518
LIG_FHA_1	1092	1098	PF00498	0.410
LIG_FHA_1	122	128	PF00498	0.735
LIG_FHA_1	198	204	PF00498	0.566
LIG_FHA_1	359	365	PF00498	0.538
LIG_FHA_1	449	455	PF00498	0.464
LIG_FHA_1	470	476	PF00498	0.530
LIG_FHA_1	517	523	PF00498	0.557
LIG_FHA_1	52	58	PF00498	0.804
LIG_FHA_1	810	816	PF00498	0.689
LIG_FHA_1	821	827	PF00498	0.767
LIG_FHA_1	850	856	PF00498	0.659
LIG_FHA_2	1042	1048	PF00498	0.637
LIG_FHA_2	263	269	PF00498	0.522
LIG_FHA_2	404	410	PF00498	0.651
LIG_FHA_2	506	512	PF00498	0.700
LIG_FHA_2	621	627	PF00498	0.531
LIG_FHA_2	7	13	PF00498	0.509
LIG_FHA_2	80	86	PF00498	0.571
LIG_FHA_2	817	823	PF00498	0.815
LIG_FHA_2	971	977	PF00498	0.549
LIG_IBAR_NPY_1	610	612	PF08397	0.535
LIG_LIR_Apic_2	36	41	PF02991	0.537
LIG_LIR_Apic_2	483	488	PF02991	0.548
LIG_LIR_Apic_2	825	831	PF02991	0.559
LIG_LIR_Gen_1	331	340	PF02991	0.632
LIG_LIR_Gen_1	921	930	PF02991	0.558
LIG_LIR_Nem_3	1023	1029	PF02991	0.488
LIG_LIR_Nem_3	174	178	PF02991	0.591
LIG_LIR_Nem_3	331	337	PF02991	0.621
LIG_LIR_Nem_3	420	426	PF02991	0.567
LIG_LIR_Nem_3	917	923	PF02991	0.733
LIG_LIR_Nem_3	976	982	PF02991	0.551
LIG_LIR_Nem_3	990	996	PF02991	0.518
LIG_MLH1_MIPbox_1	235	239	PF16413	0.323
LIG_MLH1_MIPbox_1	419	423	PF16413	0.511
LIG_PDZ_Wminus1_1	1098	1100	PF00595	0.429
LIG_Pex14_2	679	683	PF04695	0.538
LIG_REV1ctd_RIR_1	236	244	PF16727	0.327
LIG_REV1ctd_RIR_1	420	428	PF16727	0.507
LIG_RPA_C_Fungi	290	302	PF08784	0.558
LIG_SH2_CRK	175	179	PF00017	0.550
LIG_SH2_CRK	435	439	PF00017	0.776
LIG_SH2_NCK_1	330	334	PF00017	0.341
LIG_SH2_PTP2	334	337	PF00017	0.676
LIG_SH2_STAP1	330	334	PF00017	0.468
LIG_SH2_STAP1	348	352	PF00017	0.465
LIG_SH2_STAP1	975	979	PF00017	0.554
LIG_SH2_STAT5	1029	1032	PF00017	0.543
LIG_SH2_STAT5	297	300	PF00017	0.370
LIG_SH2_STAT5	334	337	PF00017	0.658
LIG_SH2_STAT5	469	472	PF00017	0.528
LIG_SH2_STAT5	993	996	PF00017	0.658
LIG_SH3_1	597	603	PF00018	0.542
LIG_SH3_3	1087	1093	PF00018	0.496
LIG_SH3_3	140	146	PF00018	0.810
LIG_SH3_3	196	202	PF00018	0.622
LIG_SH3_3	26	32	PF00018	0.543
LIG_SH3_3	374	380	PF00018	0.653
LIG_SH3_3	388	394	PF00018	0.567
LIG_SH3_3	510	516	PF00018	0.707
LIG_SH3_3	521	527	PF00018	0.739
LIG_SH3_3	597	603	PF00018	0.794
LIG_SH3_3	605	611	PF00018	0.654
LIG_SH3_3	681	687	PF00018	0.542
LIG_SH3_3	926	932	PF00018	0.706
LIG_SH3_3	949	955	PF00018	0.713
LIG_SUMO_SIM_par_1	1006	1015	PF11976	0.746
LIG_SUMO_SIM_par_1	281	287	PF11976	0.536
LIG_SUMO_SIM_par_1	822	827	PF11976	0.825
LIG_TRAF2_1	1093	1096	PF00917	0.497
LIG_TRAF2_1	146	149	PF00917	0.821
LIG_TRAF2_1	154	157	PF00917	0.707
LIG_TRAF2_1	538	541	PF00917	0.707
LIG_TRAF2_1	756	759	PF00917	0.514
LIG_TRAF2_1	962	965	PF00917	0.562
LIG_UBA3_1	253	262	PF00899	0.587
LIG_WRC_WIRS_1	621	626	PF05994	0.531
LIG_WW_3	522	526	PF00397	0.554
LIG_WW_3	712	716	PF00397	0.497
MOD_CDK_SPK_2	11	16	PF00069	0.553
MOD_CDK_SPxK_1	700	706	PF00069	0.618
MOD_CDK_SPxxK_3	15	22	PF00069	0.624
MOD_CDK_SPxxK_3	358	365	PF00069	0.700
MOD_CDK_SPxxK_3	390	397	PF00069	0.653
MOD_CDK_SPxxK_3	541	548	PF00069	0.544
MOD_CDK_SPxxK_3	599	606	PF00069	0.809
MOD_CDK_SPxxK_3	723	730	PF00069	0.541
MOD_CDK_SPxxK_3	941	948	PF00069	0.678
MOD_CK1_1	1001	1007	PF00069	0.780
MOD_CK1_1	102	108	PF00069	0.802
MOD_CK1_1	1035	1041	PF00069	0.610
MOD_CK1_1	115	121	PF00069	0.575
MOD_CK1_1	151	157	PF00069	0.710
MOD_CK1_1	174	180	PF00069	0.549
MOD_CK1_1	350	356	PF00069	0.777
MOD_CK1_1	404	410	PF00069	0.678
MOD_CK1_1	417	423	PF00069	0.576
MOD_CK1_1	437	443	PF00069	0.663
MOD_CK1_1	460	466	PF00069	0.435
MOD_CK1_1	49	55	PF00069	0.535
MOD_CK1_1	550	556	PF00069	0.730
MOD_CK1_1	557	563	PF00069	0.723
MOD_CK1_1	677	683	PF00069	0.729
MOD_CK1_1	696	702	PF00069	0.571
MOD_CK1_1	732	738	PF00069	0.598
MOD_CK1_1	745	751	PF00069	0.781
MOD_CK1_1	75	81	PF00069	0.705
MOD_CK1_1	801	807	PF00069	0.773
MOD_CK1_1	921	927	PF00069	0.600
MOD_CK1_1	983	989	PF00069	0.633
MOD_CK2_1	1041	1047	PF00069	0.635
MOD_CK2_1	151	157	PF00069	0.828
MOD_CK2_1	262	268	PF00069	0.529
MOD_CK2_1	620	626	PF00069	0.532
MOD_CK2_1	792	798	PF00069	0.664
MOD_CK2_1	968	974	PF00069	0.659
MOD_GlcNHglycan	1000	1003	PF01048	0.744
MOD_GlcNHglycan	1037	1040	PF01048	0.614
MOD_GlcNHglycan	117	120	PF01048	0.548
MOD_GlcNHglycan	207	210	PF01048	0.699
MOD_GlcNHglycan	340	343	PF01048	0.719
MOD_GlcNHglycan	349	352	PF01048	0.611
MOD_GlcNHglycan	416	419	PF01048	0.657
MOD_GlcNHglycan	439	442	PF01048	0.770
MOD_GlcNHglycan	461	465	PF01048	0.537
MOD_GlcNHglycan	49	52	PF01048	0.671
MOD_GlcNHglycan	531	534	PF01048	0.732
MOD_GlcNHglycan	535	538	PF01048	0.805
MOD_GlcNHglycan	575	578	PF01048	0.708
MOD_GlcNHglycan	582	585	PF01048	0.774
MOD_GlcNHglycan	590	593	PF01048	0.796
MOD_GlcNHglycan	63	66	PF01048	0.748
MOD_GlcNHglycan	636	639	PF01048	0.746
MOD_GlcNHglycan	651	654	PF01048	0.817
MOD_GlcNHglycan	67	70	PF01048	0.731
MOD_GlcNHglycan	737	740	PF01048	0.555
MOD_GlcNHglycan	74	77	PF01048	0.682
MOD_GlcNHglycan	747	750	PF01048	0.793
MOD_GlcNHglycan	754	757	PF01048	0.687
MOD_GlcNHglycan	789	793	PF01048	0.763
MOD_GlcNHglycan	869	873	PF01048	0.744
MOD_GSK3_1	1004	1011	PF00069	0.507
MOD_GSK3_1	103	110	PF00069	0.680
MOD_GSK3_1	11	18	PF00069	0.571
MOD_GSK3_1	117	124	PF00069	0.642
MOD_GSK3_1	159	166	PF00069	0.744
MOD_GSK3_1	167	174	PF00069	0.725
MOD_GSK3_1	338	345	PF00069	0.681
MOD_GSK3_1	350	357	PF00069	0.556
MOD_GSK3_1	397	404	PF00069	0.790
MOD_GSK3_1	41	48	PF00069	0.720
MOD_GSK3_1	414	421	PF00069	0.545
MOD_GSK3_1	437	444	PF00069	0.668
MOD_GSK3_1	49	56	PF00069	0.751
MOD_GSK3_1	501	508	PF00069	0.754
MOD_GSK3_1	529	536	PF00069	0.800
MOD_GSK3_1	550	557	PF00069	0.715
MOD_GSK3_1	569	576	PF00069	0.639
MOD_GSK3_1	580	587	PF00069	0.792
MOD_GSK3_1	602	609	PF00069	0.608
MOD_GSK3_1	61	68	PF00069	0.538
MOD_GSK3_1	639	646	PF00069	0.750
MOD_GSK3_1	670	677	PF00069	0.652
MOD_GSK3_1	696	703	PF00069	0.735
MOD_GSK3_1	72	79	PF00069	0.525
MOD_GSK3_1	745	752	PF00069	0.730
MOD_GSK3_1	780	787	PF00069	0.696
MOD_GSK3_1	788	795	PF00069	0.586
MOD_GSK3_1	798	805	PF00069	0.557
MOD_GSK3_1	816	823	PF00069	0.508
MOD_GSK3_1	835	842	PF00069	0.517
MOD_GSK3_1	846	853	PF00069	0.664
MOD_GSK3_1	921	928	PF00069	0.789
MOD_GSK3_1	94	101	PF00069	0.739
MOD_GSK3_1	970	977	PF00069	0.612
MOD_GSK3_1	982	989	PF00069	0.756
MOD_LATS_1	818	824	PF00433	0.817
MOD_N-GLC_1	798	803	PF02516	0.543
MOD_N-GLC_1	980	985	PF02516	0.576
MOD_N-GLC_2	768	770	PF02516	0.485
MOD_NEK2_1	1086	1091	PF00069	0.625
MOD_NEK2_1	117	122	PF00069	0.524
MOD_NEK2_1	171	176	PF00069	0.716
MOD_NEK2_1	649	654	PF00069	0.786
MOD_NEK2_1	708	713	PF00069	0.618
MOD_NEK2_1	734	739	PF00069	0.639
MOD_NEK2_1	788	793	PF00069	0.830
MOD_NEK2_1	807	812	PF00069	0.495
MOD_NEK2_1	980	985	PF00069	0.762
MOD_NEK2_2	418	423	PF00069	0.509
MOD_NEK2_2	645	650	PF00069	0.567
MOD_NEK2_2	975	980	PF00069	0.554
MOD_OFUCOSY	765	772	PF10250	0.485
MOD_PIKK_1	1091	1097	PF00454	0.331
MOD_PIKK_1	178	184	PF00454	0.816
MOD_PIKK_1	191	197	PF00454	0.530
MOD_PIKK_1	350	356	PF00454	0.645
MOD_PIKK_1	517	523	PF00454	0.557
MOD_PIKK_1	567	573	PF00454	0.723
MOD_PIKK_1	857	863	PF00454	0.562
MOD_PK_1	434	440	PF00069	0.675
MOD_PKA_1	103	109	PF00069	0.799
MOD_PKA_1	189	195	PF00069	0.681
MOD_PKA_1	262	268	PF00069	0.629
MOD_PKA_1	397	403	PF00069	0.585
MOD_PKA_1	46	52	PF00069	0.531
MOD_PKA_1	501	507	PF00069	0.535
MOD_PKA_1	567	573	PF00069	0.747
MOD_PKA_1	606	612	PF00069	0.538
MOD_PKA_2	102	108	PF00069	0.758
MOD_PKA_2	1020	1026	PF00069	0.469
MOD_PKA_2	115	121	PF00069	0.575
MOD_PKA_2	151	157	PF00069	0.574
MOD_PKA_2	189	195	PF00069	0.805
MOD_PKA_2	21	27	PF00069	0.611
MOD_PKA_2	262	268	PF00069	0.521
MOD_PKA_2	342	348	PF00069	0.648
MOD_PKA_2	397	403	PF00069	0.659
MOD_PKA_2	404	410	PF00069	0.775
MOD_PKA_2	45	51	PF00069	0.531
MOD_PKA_2	501	507	PF00069	0.803
MOD_PKA_2	547	553	PF00069	0.599
MOD_PKA_2	567	573	PF00069	0.747
MOD_PKA_2	606	612	PF00069	0.681
MOD_PKA_2	614	620	PF00069	0.707
MOD_PKA_2	649	655	PF00069	0.854
MOD_PKA_2	729	735	PF00069	0.826
MOD_PKA_2	902	908	PF00069	0.613
MOD_PKB_1	901	909	PF00069	0.562
MOD_Plk_1	108	114	PF00069	0.618
MOD_Plk_1	167	173	PF00069	0.711
MOD_Plk_1	783	789	PF00069	0.681
MOD_Plk_1	903	909	PF00069	0.559
MOD_Plk_1	975	981	PF00069	0.553
MOD_Plk_2-3	784	790	PF00069	0.737
MOD_Plk_2-3	822	828	PF00069	0.826
MOD_Plk_4	1008	1014	PF00069	0.493
MOD_Plk_4	1086	1092	PF00069	0.620
MOD_Plk_4	233	239	PF00069	0.605
MOD_Plk_4	33	39	PF00069	0.523
MOD_Plk_4	342	348	PF00069	0.588
MOD_Plk_4	354	360	PF00069	0.742
MOD_Plk_4	397	403	PF00069	0.824
MOD_Plk_4	418	424	PF00069	0.511
MOD_Plk_4	560	566	PF00069	0.787
MOD_Plk_4	798	804	PF00069	0.707
MOD_Plk_4	975	981	PF00069	0.608
MOD_Plk_4	987	993	PF00069	0.753
MOD_ProDKin_1	1001	1007	PF00069	0.655
MOD_ProDKin_1	11	17	PF00069	0.706
MOD_ProDKin_1	121	127	PF00069	0.732
MOD_ProDKin_1	28	34	PF00069	0.687
MOD_ProDKin_1	358	364	PF00069	0.698
MOD_ProDKin_1	381	387	PF00069	0.693
MOD_ProDKin_1	390	396	PF00069	0.709
MOD_ProDKin_1	489	495	PF00069	0.592
MOD_ProDKin_1	541	547	PF00069	0.722
MOD_ProDKin_1	550	556	PF00069	0.680
MOD_ProDKin_1	557	563	PF00069	0.674
MOD_ProDKin_1	569	575	PF00069	0.731
MOD_ProDKin_1	599	605	PF00069	0.810
MOD_ProDKin_1	670	676	PF00069	0.747
MOD_ProDKin_1	683	689	PF00069	0.715
MOD_ProDKin_1	693	699	PF00069	0.607
MOD_ProDKin_1	700	706	PF00069	0.685
MOD_ProDKin_1	723	729	PF00069	0.706
MOD_ProDKin_1	742	748	PF00069	0.668
MOD_ProDKin_1	775	781	PF00069	0.522
MOD_ProDKin_1	839	845	PF00069	0.773
MOD_ProDKin_1	855	861	PF00069	0.833
MOD_ProDKin_1	925	931	PF00069	0.825
MOD_ProDKin_1	941	947	PF00069	0.592
MOD_ProDKin_1	951	957	PF00069	0.714
MOD_ProDKin_1	963	969	PF00069	0.691
MOD_ProDKin_1	983	989	PF00069	0.657
MOD_SUMO_rev_2	43	49	PF00179	0.533
TRG_DiLeu_BaLyEn_6	359	364	PF01217	0.546
TRG_DiLeu_BaLyEn_6	627	632	PF01217	0.528
TRG_ENDOCYTIC_2	175	178	PF00928	0.594
TRG_ENDOCYTIC_2	334	337	PF00928	0.679
TRG_ENDOCYTIC_2	435	438	PF00928	0.776
TRG_ENDOCYTIC_2	923	926	PF00928	0.627
TRG_ENDOCYTIC_2	993	996	PF00928	0.525
TRG_ER_diArg_1	228	230	PF00400	0.597
TRG_ER_diArg_1	501	503	PF00400	0.528
TRG_ER_diArg_1	566	568	PF00400	0.761
TRG_ER_diArg_1	632	634	PF00400	0.757
TRG_ER_diArg_1	774	776	PF00400	0.789
TRG_ER_diArg_1	883	885	PF00400	0.802
TRG_ER_diArg_1	932	935	PF00400	0.843
TRG_NES_CRM1_1	136	149	PF08389	0.562

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IA74	Leptomonas seymouri	34%	75%
A0A3S7X1D0	Leishmania donovani	63%	75%
A4I3G8	Leishmania infantum	63%	75%
E9AZQ7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	63%	75%
Q4Q8H6	Leishmania major	63%	100%