ATP synthase subunit d, mitochondrial

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HH02_LEIBR

TriTrypDb:

LbrM.28.3210 , LBRM2903_280039900

Length:

235

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HH02

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HH02

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	133	135	PF00675	0.443
CLV_NRD_NRD_1	233	235	PF00675	0.664
CLV_PCSK_FUR_1	145	149	PF00082	0.533
CLV_PCSK_KEX2_1	147	149	PF00082	0.463
CLV_PCSK_PC1ET2_1	147	149	PF00082	0.456
CLV_PCSK_SKI1_1	105	109	PF00082	0.504
CLV_PCSK_SKI1_1	204	208	PF00082	0.737
CLV_Separin_Metazoa	229	233	PF03568	0.523
DEG_APCC_DBOX_1	66	74	PF00400	0.618
DEG_Nend_UBRbox_1	1	4	PF02207	0.639
DEG_SCF_FBW7_1	28	35	PF00400	0.425
DOC_ANK_TNKS_1	52	59	PF00023	0.547
DOC_CKS1_1	29	34	PF01111	0.428
DOC_PP2B_LxvP_1	7	10	PF13499	0.494
DOC_USP7_MATH_1	32	36	PF00917	0.479
DOC_WW_Pin1_4	28	33	PF00397	0.433
DOC_WW_Pin1_4	72	77	PF00397	0.498
LIG_BRCT_BRCA1_1	158	162	PF00533	0.392
LIG_CaM_IQ_9	39	55	PF13499	0.552
LIG_FHA_1	23	29	PF00498	0.592
LIG_FHA_1	52	58	PF00498	0.608
LIG_FHA_2	109	115	PF00498	0.441
LIG_FHA_2	39	45	PF00498	0.563
LIG_LIR_Gen_1	159	169	PF02991	0.424
LIG_LIR_Gen_1	91	100	PF02991	0.441
LIG_LIR_Nem_3	130	136	PF02991	0.502
LIG_LIR_Nem_3	159	165	PF02991	0.537
LIG_LIR_Nem_3	91	97	PF02991	0.436
LIG_MLH1_MIPbox_1	158	162	PF16413	0.392
LIG_NRBOX	226	232	PF00104	0.512
LIG_SH2_STAT5	161	164	PF00017	0.548
LIG_SH2_STAT5	64	67	PF00017	0.605
LIG_SH3_2	100	105	PF14604	0.441
LIG_SH3_3	193	199	PF00018	0.525
LIG_SH3_3	97	103	PF00018	0.445
LIG_SUMO_SIM_par_1	182	188	PF11976	0.594
LIG_TRAF2_1	111	114	PF00917	0.446
LIG_TRAF2_1	209	212	PF00917	0.531
LIG_TRAF2_1	41	44	PF00917	0.554
LIG_UBA3_1	38	47	PF00899	0.392
MOD_CK1_1	8	14	PF00069	0.503
MOD_CK2_1	108	114	PF00069	0.450
MOD_CK2_1	206	212	PF00069	0.545
MOD_CK2_1	38	44	PF00069	0.559
MOD_CK2_1	45	51	PF00069	0.362
MOD_CK2_1	68	74	PF00069	0.589
MOD_GlcNHglycan	20	23	PF01048	0.723
MOD_GlcNHglycan	208	211	PF01048	0.576
MOD_GlcNHglycan	34	37	PF01048	0.603
MOD_GSK3_1	18	25	PF00069	0.609
MOD_GSK3_1	28	35	PF00069	0.709
MOD_GSK3_1	47	54	PF00069	0.573
MOD_GSK3_1	68	75	PF00069	0.607
MOD_NEK2_1	38	43	PF00069	0.525
MOD_PIKK_1	156	162	PF00454	0.409
MOD_PKA_2	188	194	PF00069	0.689
MOD_PKA_2	5	11	PF00069	0.580
MOD_Plk_1	204	210	PF00069	0.615
MOD_Plk_1	215	221	PF00069	0.451
MOD_Plk_1	23	29	PF00069	0.503
MOD_Plk_1	68	74	PF00069	0.617
MOD_Plk_2-3	45	51	PF00069	0.457
MOD_Plk_4	24	30	PF00069	0.557
MOD_Plk_4	34	40	PF00069	0.531
MOD_ProDKin_1	28	34	PF00069	0.429
MOD_ProDKin_1	72	78	PF00069	0.490
MOD_SUMO_for_1	115	118	PF00179	0.488
MOD_SUMO_for_1	46	49	PF00179	0.449
MOD_SUMO_rev_2	44	48	PF00179	0.393
MOD_SUMO_rev_2	83	90	PF00179	0.552
TRG_DiLeu_BaLyEn_6	196	201	PF01217	0.471
TRG_Pf-PMV_PEXEL_1	134	139	PF00026	0.315
TRG_Pf-PMV_PEXEL_1	40	44	PF00026	0.503

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HYA2	Leptomonas seymouri	62%	95%
A0A0S4IVM1	Bodo saltans	37%	100%
A0A1X0NS70	Trypanosomatidae	42%	100%
A0A3S7X226	Leishmania donovani	76%	100%
A4I434	Leishmania infantum	78%	100%
E9B0C1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	77%	100%
Q4Q7W3	Leishmania major	76%	100%