LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HH00_LEIBR
TriTrypDb:
LbrM.28.3190 , LBRM2903_280039700
Length:
121

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HH00
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HH00

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_KEX2_1 42 44 PF00082 0.668
CLV_PCSK_PC1ET2_1 42 44 PF00082 0.732
CLV_PCSK_SKI1_1 3 7 PF00082 0.692
CLV_PCSK_SKI1_1 95 99 PF00082 0.461
DEG_Nend_UBRbox_3 1 3 PF02207 0.525
DEG_SPOP_SBC_1 59 63 PF00917 0.472
DOC_CKS1_1 10 15 PF01111 0.525
DOC_USP7_MATH_1 15 19 PF00917 0.680
DOC_USP7_MATH_1 60 64 PF00917 0.614
DOC_WW_Pin1_4 21 26 PF00397 0.718
DOC_WW_Pin1_4 9 14 PF00397 0.704
LIG_eIF4E_1 105 111 PF01652 0.572
LIG_eIF4E_1 49 55 PF01652 0.473
LIG_SH2_STAT5 105 108 PF00017 0.561
LIG_SH2_STAT5 49 52 PF00017 0.681
LIG_SH3_3 7 13 PF00018 0.526
MOD_CK1_1 19 25 PF00069 0.794
MOD_CK1_1 58 64 PF00069 0.618
MOD_CK1_1 66 72 PF00069 0.587
MOD_CK2_1 15 21 PF00069 0.670
MOD_CK2_1 71 77 PF00069 0.603
MOD_DYRK1A_RPxSP_1 9 13 PF00069 0.590
MOD_GlcNHglycan 57 60 PF01048 0.614
MOD_GlcNHglycan 89 92 PF01048 0.537
MOD_GSK3_1 11 18 PF00069 0.710
MOD_GSK3_1 33 40 PF00069 0.740
MOD_GSK3_1 55 62 PF00069 0.661
MOD_NEK2_1 28 33 PF00069 0.502
MOD_NEK2_2 60 65 PF00069 0.472
MOD_PKA_2 19 25 PF00069 0.751
MOD_PKA_2 38 44 PF00069 0.483
MOD_Plk_1 66 72 PF00069 0.555
MOD_Plk_4 50 56 PF00069 0.575
MOD_Plk_4 60 66 PF00069 0.707
MOD_ProDKin_1 21 27 PF00069 0.714
MOD_ProDKin_1 9 15 PF00069 0.702
TRG_Pf-PMV_PEXEL_1 87 92 PF00026 0.363

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P5Y8 Leptomonas seymouri 43% 99%
A0A3S5H7K3 Leishmania donovani 75% 100%
A4I432 Leishmania infantum 74% 100%
D0A8X6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 36% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS