CST complex subunit CTC1

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HGZ5_LEIBR

TriTrypDb:

LbrM.28.3130 , LBRM2903_280038900

Length:

179

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HGZ5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HGZ5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	110	114	PF00656	0.407
CLV_C14_Caspase3-7	156	160	PF00656	0.475
CLV_PCSK_SKI1_1	43	47	PF00082	0.414
DEG_Nend_UBRbox_2	1	3	PF02207	0.545
DEG_SPOP_SBC_1	123	127	PF00917	0.309
DOC_CKS1_1	53	58	PF01111	0.532
DOC_MAPK_gen_1	133	142	PF00069	0.515
DOC_MAPK_gen_1	64	71	PF00069	0.475
DOC_MAPK_MEF2A_6	136	144	PF00069	0.436
DOC_MAPK_MEF2A_6	15	24	PF00069	0.426
DOC_MAPK_MEF2A_6	64	71	PF00069	0.475
DOC_PP1_RVXF_1	13	20	PF00149	0.550
DOC_PP1_RVXF_1	66	72	PF00149	0.468
DOC_PP2B_LxvP_1	96	99	PF13499	0.509
DOC_PP4_FxxP_1	118	121	PF00568	0.343
DOC_PP4_FxxP_1	81	84	PF00568	0.481
DOC_USP7_MATH_1	121	125	PF00917	0.522
DOC_WW_Pin1_4	111	116	PF00397	0.398
DOC_WW_Pin1_4	142	147	PF00397	0.467
DOC_WW_Pin1_4	52	57	PF00397	0.629
LIG_14-3-3_CanoR_1	25	29	PF00244	0.523
LIG_14-3-3_CanoR_1	91	96	PF00244	0.302
LIG_Actin_WH2_2	10	27	PF00022	0.523
LIG_BIR_III_4	150	154	PF00653	0.452
LIG_FHA_1	123	129	PF00498	0.436
LIG_FHA_2	108	114	PF00498	0.638
LIG_LIR_Gen_1	147	157	PF02991	0.511
LIG_LIR_Gen_1	42	53	PF02991	0.452
LIG_LIR_Nem_3	147	152	PF02991	0.538
LIG_LIR_Nem_3	16	22	PF02991	0.473
LIG_LIR_Nem_3	42	48	PF02991	0.439
LIG_PDZ_Class_2	174	179	PF00595	0.539
LIG_Pex14_2	71	75	PF04695	0.344
LIG_SH2_STAP1	4	8	PF00017	0.464
LIG_SH3_3	109	115	PF00018	0.521
LIG_SH3_3	14	20	PF00018	0.529
LIG_SH3_3	50	56	PF00018	0.558
LIG_SUMO_SIM_anti_2	86	91	PF11976	0.329
MOD_CK1_1	124	130	PF00069	0.437
MOD_CK1_1	3	9	PF00069	0.611
MOD_CK1_1	57	63	PF00069	0.522
MOD_CK2_1	157	163	PF00069	0.593
MOD_GlcNHglycan	56	59	PF01048	0.435
MOD_GSK3_1	107	114	PF00069	0.576
MOD_GSK3_1	153	160	PF00069	0.622
MOD_GSK3_1	43	50	PF00069	0.416
MOD_NEK2_1	107	112	PF00069	0.430
MOD_NEK2_1	140	145	PF00069	0.364
MOD_NEK2_1	24	29	PF00069	0.509
MOD_NEK2_1	71	76	PF00069	0.491
MOD_PKA_2	24	30	PF00069	0.393
MOD_Plk_1	140	146	PF00069	0.315
MOD_Plk_1	6	12	PF00069	0.500
MOD_Plk_4	24	30	PF00069	0.421
MOD_ProDKin_1	111	117	PF00069	0.382
MOD_ProDKin_1	142	148	PF00069	0.472
MOD_ProDKin_1	52	58	PF00069	0.634
MOD_SUMO_rev_2	38	45	PF00179	0.432
TRG_DiLeu_BaEn_1	18	23	PF01217	0.486
TRG_DiLeu_BaLyEn_6	112	117	PF01217	0.404
TRG_ER_diArg_1	66	69	PF00400	0.263
TRG_Pf-PMV_PEXEL_1	155	159	PF00026	0.327

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IKA8	Leptomonas seymouri	46%	99%
A0A0S4J055	Bodo saltans	34%	95%
A0A1X0NR08	Trypanosomatidae	30%	87%
A0A3R7KM85	Trypanosoma rangeli	31%	100%
A0A3S7X216	Leishmania donovani	79%	100%
A4I427	Leishmania infantum	79%	100%
D0A8Y0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	100%
E9B0B4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	80%	100%
Q4Q7X0	Leishmania major	81%	99%