LeishMANIAdb
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Malate dehydrogenase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Malate dehydrogenase
Gene product:
cytosolic malate dehydrogenase
Species:
Leishmania braziliensis
UniProt:
A4HGY9_LEIBR
TriTrypDb:
LbrM.28.3070 , LBRM2903_280038300
Length:
324

Annotations

LeishMANIAdb annotations

A group of metabolic enzymes without any likely TM segment. Very conserved in Eukaryota.

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 4
Forrest at al. (procyclic) no yes: 4
Silverman et al. no yes: 2
Pissara et al. yes yes: 8
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 4
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Cellular components
Term Name Level Count
GO:0005829 cytosol 2 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

A4HGY9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HGY9

PDB structure(s): 4h7p_A , 4h7p_B , 4i1i_A , 4i1i_B

Function

Biological processes
Term Name Level Count
GO:0006082 organic acid metabolic process 3 10
GO:0006099 tricarboxylic acid cycle 3 10
GO:0006108 malate metabolic process 7 10
GO:0008152 metabolic process 1 10
GO:0009987 cellular process 1 10
GO:0019752 carboxylic acid metabolic process 5 10
GO:0043436 oxoacid metabolic process 4 10
GO:0043648 dicarboxylic acid metabolic process 6 10
GO:0044237 cellular metabolic process 2 10
GO:0044238 primary metabolic process 2 10
GO:0044281 small molecule metabolic process 2 10
GO:0071704 organic substance metabolic process 2 10
GO:0006107 oxaloacetate metabolic process 7 1
GO:0006734 NADH metabolic process 2 1
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 10
GO:0016491 oxidoreductase activity 2 10
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 3 10
GO:0016615 malate dehydrogenase activity 4 10
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4 10
GO:0030060 L-malate dehydrogenase activity 5 10
GO:0000166 nucleotide binding 3 1
GO:0005488 binding 1 1
GO:0036094 small molecule binding 2 1
GO:0097159 organic cyclic compound binding 2 1
GO:1901265 nucleoside phosphate binding 3 1
GO:1901363 heterocyclic compound binding 2 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 168 170 PF00675 0.480
CLV_NRD_NRD_1 90 92 PF00675 0.427
CLV_NRD_NRD_1 96 98 PF00675 0.354
CLV_PCSK_SKI1_1 106 110 PF00082 0.371
CLV_PCSK_SKI1_1 150 154 PF00082 0.497
CLV_PCSK_SKI1_1 25 29 PF00082 0.512
CLV_PCSK_SKI1_1 74 78 PF00082 0.395
CLV_PCSK_SKI1_1 98 102 PF00082 0.363
DEG_APCC_DBOX_1 96 104 PF00400 0.512
DEG_COP1_1 188 195 PF00400 0.450
DOC_CKS1_1 254 259 PF01111 0.276
DOC_MAPK_FxFP_2 281 284 PF00069 0.395
DOC_MAPK_gen_1 223 232 PF00069 0.470
DOC_MAPK_gen_1 97 103 PF00069 0.457
DOC_PP1_RVXF_1 72 78 PF00149 0.393
DOC_PP4_FxxP_1 281 284 PF00568 0.395
DOC_WW_Pin1_4 200 205 PF00397 0.512
DOC_WW_Pin1_4 253 258 PF00397 0.395
LIG_14-3-3_CanoR_1 150 158 PF00244 0.525
LIG_14-3-3_CanoR_1 162 167 PF00244 0.470
LIG_AP2alpha_1 214 218 PF02296 0.259
LIG_BIR_II_1 1 5 PF00653 0.528
LIG_Clathr_ClatBox_1 39 43 PF01394 0.395
LIG_eIF4E_1 17 23 PF01652 0.371
LIG_FHA_1 132 138 PF00498 0.359
LIG_FHA_1 225 231 PF00498 0.259
LIG_FHA_1 79 85 PF00498 0.259
LIG_FHA_2 154 160 PF00498 0.371
LIG_FHA_2 210 216 PF00498 0.422
LIG_FHA_2 309 315 PF00498 0.353
LIG_FHA_2 31 37 PF00498 0.512
LIG_IBAR_NPY_1 271 273 PF08397 0.395
LIG_LIR_Apic_2 278 284 PF02991 0.411
LIG_LIR_Gen_1 258 267 PF02991 0.475
LIG_LIR_Nem_3 291 295 PF02991 0.365
LIG_LIR_Nem_3 58 64 PF02991 0.359
LIG_PDZ_Class_2 319 324 PF00595 0.493
LIG_Pex14_2 214 218 PF04695 0.306
LIG_RPA_C_Fungi 157 169 PF08784 0.470
LIG_SH2_CRK 17 21 PF00017 0.371
LIG_SH2_GRB2like 267 270 PF00017 0.259
LIG_SH2_NCK_1 17 21 PF00017 0.512
LIG_SH2_NCK_1 273 277 PF00017 0.460
LIG_SH2_STAP1 78 82 PF00017 0.259
LIG_SH2_STAT5 261 264 PF00017 0.512
LIG_SH3_3 125 131 PF00018 0.388
LIG_SUMO_SIM_anti_2 81 86 PF11976 0.306
LIG_SUMO_SIM_par_1 136 142 PF11976 0.470
LIG_SUMO_SIM_par_1 38 43 PF11976 0.371
LIG_TRFH_1 17 21 PF08558 0.371
LIG_TYR_ITIM 15 20 PF00017 0.371
LIG_UBA3_1 137 141 PF00899 0.470
MOD_CDK_SPxK_1 200 206 PF00069 0.512
MOD_CK1_1 237 243 PF00069 0.395
MOD_CK2_1 30 36 PF00069 0.512
MOD_CK2_1 308 314 PF00069 0.353
MOD_GlcNHglycan 141 144 PF01048 0.500
MOD_GlcNHglycan 196 199 PF01048 0.392
MOD_GlcNHglycan 236 239 PF01048 0.371
MOD_GSK3_1 233 240 PF00069 0.372
MOD_GSK3_1 279 286 PF00069 0.385
MOD_LATS_1 160 166 PF00433 0.512
MOD_LATS_1 231 237 PF00433 0.259
MOD_N-GLC_1 185 190 PF02516 0.371
MOD_NEK2_1 139 144 PF00069 0.431
MOD_NEK2_1 199 204 PF00069 0.467
MOD_NEK2_1 279 284 PF00069 0.371
MOD_NEK2_1 308 313 PF00069 0.427
MOD_PIKK_1 173 179 PF00454 0.512
MOD_PIKK_1 187 193 PF00454 0.371
MOD_PKA_2 209 215 PF00069 0.259
MOD_PKA_2 224 230 PF00069 0.197
MOD_Plk_1 210 216 PF00069 0.259
MOD_Plk_1 78 84 PF00069 0.259
MOD_Plk_4 162 168 PF00069 0.512
MOD_ProDKin_1 200 206 PF00069 0.512
MOD_ProDKin_1 253 259 PF00069 0.395
MOD_SUMO_rev_2 314 322 PF00179 0.365
TRG_DiLeu_BaEn_1 96 101 PF01217 0.416
TRG_DiLeu_BaLyEn_6 18 23 PF01217 0.371
TRG_DiLeu_BaLyEn_6 35 40 PF01217 0.371
TRG_DiLeu_BaLyEn_6 59 64 PF01217 0.371
TRG_ENDOCYTIC_2 17 20 PF00928 0.371
TRG_ENDOCYTIC_2 261 264 PF00928 0.512
TRG_ER_diArg_1 222 225 PF00400 0.473
TRG_Pf-PMV_PEXEL_1 38 43 PF00026 0.411
TRG_Pf-PMV_PEXEL_1 98 102 PF00026 0.382

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P6H7 Leptomonas seymouri 28% 100%
A0A0N1ILF3 Leptomonas seymouri 27% 100%
A0A0S4IRB3 Bodo saltans 60% 98%
A0A1X0NQI1 Trypanosomatidae 57% 98%
A0A1X0P752 Trypanosomatidae 30% 100%
A0A3Q8IH05 Leishmania donovani 84% 100%
A0A3Q8IKK8 Leishmania donovani 27% 98%
A0A3R7MEL1 Trypanosoma rangeli 53% 97%
A0A3S7WVE3 Leishmania donovani 30% 100%
A0A422NMV1 Trypanosoma rangeli 30% 100%
A0AZ43 Burkholderia cenocepacia (strain HI2424) 50% 99%
A0KG16 Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049) 32% 100%
A0L113 Shewanella sp. (strain ANA-3) 29% 100%
A0L5T9 Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1) 44% 99%
A0LFF8 Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) 48% 98%
A0PVV1 Mycobacterium ulcerans (strain Agy99) 50% 98%
A0Q6K3 Francisella tularensis subsp. novicida (strain U112) 25% 100%
A0QCI6 Mycobacterium avium (strain 104) 51% 98%
A1AGC9 Escherichia coli O1:K1 / APEC 29% 100%
A1JIV0 Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081) 29% 100%
A1K5Q9 Azoarcus sp. (strain BH72) 48% 98%
A1KI28 Mycobacterium bovis (strain BCG / Pasteur 1173P2) 51% 98%
A1R2B5 Paenarthrobacter aurescens (strain TC1) 48% 99%
A1RFX8 Shewanella sp. (strain W3-18-1) 30% 100%
A1S3C4 Shewanella amazonensis (strain ATCC BAA-1098 / SB2B) 31% 100%
A1SMP3 Nocardioides sp. (strain ATCC BAA-499 / JS614) 49% 99%
A1SRP8 Psychromonas ingrahamii (strain 37) 30% 100%
A1T9L9 Mycolicibacterium vanbaalenii (strain DSM 7251 / JCM 13017 / BCRC 16820 / KCTC 9966 / NRRL B-24157 / PYR-1) 48% 98%
A1TP96 Acidovorax citrulli (strain AAC00-1) 49% 99%
A1UZ10 Burkholderia mallei (strain SAVP1) 50% 99%
A1VRQ1 Polaromonas naphthalenivorans (strain CJ2) 49% 99%
A1W9K7 Acidovorax sp. (strain JS42) 49% 99%
A1WR02 Verminephrobacter eiseniae (strain EF01-2) 47% 99%
A1WV94 Halorhodospira halophila (strain DSM 244 / SL1) 50% 99%
A2S105 Burkholderia mallei (strain NCTC 10229) 50% 99%
A2SHT9 Methylibium petroleiphilum (strain ATCC BAA-1232 / LMG 22953 / PM1) 50% 99%
A3D075 Shewanella baltica (strain OS155 / ATCC BAA-1091) 29% 100%
A3KMX7 Bos taurus 24% 68%
A3M928 Acinetobacter baumannii (strain ATCC 17978 / CIP 53.77 / LMG 1025 / NCDC KC755 / 5377) 50% 99%
A3MBR2 Burkholderia mallei (strain NCTC 10247) 50% 99%
A3N1U6 Actinobacillus pleuropneumoniae serotype 5b (strain L20) 29% 100%
A3NM97 Burkholderia pseudomallei (strain 668) 50% 99%
A3P7Q9 Burkholderia pseudomallei (strain 1106a) 50% 99%
A3PN14 Cereibacter sphaeroides (strain ATCC 17029 / ATH 2.4.9) 27% 100%
A3QB91 Shewanella loihica (strain ATCC BAA-1088 / PV-4) 30% 100%
A4FFX3 Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338) 51% 99%
A4G5Z9 Herminiimonas arsenicoxydans 51% 98%
A4HA28 Leishmania braziliensis 31% 100%
A4HAB8 Leishmania braziliensis 25% 100%
A4HY91 Leishmania infantum 30% 100%
A4I421 Leishmania infantum 84% 100%
A4I9I4 Leishmania infantum 27% 98%
A4IY35 Francisella tularensis subsp. tularensis (strain WY96-3418) 25% 100%
A4JKE6 Burkholderia vietnamiensis (strain G4 / LMG 22486) 47% 99%
A4JM71 Burkholderia vietnamiensis (strain G4 / LMG 22486) 49% 99%
A4QGA0 Corynebacterium glutamicum (strain R) 45% 99%
A4SIV0 Aeromonas salmonicida (strain A449) 31% 100%
A4SWW0 Polynucleobacter asymbioticus (strain DSM 18221 / CIP 109841 / QLW-P1DMWA-1) 49% 98%
A4TRK3 Yersinia pestis (strain Pestoides F) 29% 100%
A4WF48 Enterobacter sp. (strain 638) 30% 100%
A4YAE8 Shewanella putrefaciens (strain CN-32 / ATCC BAA-453) 30% 100%
A4YKC5 Bradyrhizobium sp. (strain ORS 278) 28% 100%
A5E935 Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182) 28% 100%
A5G320 Acidiphilium cryptum (strain JF-5) 50% 99%
A5IEF4 Legionella pneumophila (strain Corby) 49% 98%
A5U1T8 Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) 51% 98%
A5UCQ1 Haemophilus influenzae (strain PittEE) 28% 100%
A5UIX3 Haemophilus influenzae (strain PittGG) 28% 100%
A5V5U9 Rhizorhabdus wittichii (strain DSM 6014 / CCUG 31198 / JCM 15750 / NBRC 105917 / EY 4224 / RW1) 29% 100%
A5WGM2 Psychrobacter sp. (strain PRwf-1) 50% 99%
A6Q388 Nitratiruptor sp. (strain SB155-2) 27% 100%
A6SY47 Janthinobacterium sp. (strain Marseille) 50% 98%
A6TEQ3 Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578) 31% 100%
A6WSM1 Shewanella baltica (strain OS185) 29% 100%
A6WXE7 Brucella anthropi (strain ATCC 49188 / DSM 6882 / CCUG 24695 / JCM 21032 / LMG 3331 / NBRC 15819 / NCTC 12168 / Alc 37) 25% 100%
A7FMU2 Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) 29% 100%
A7IBL9 Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2) 29% 100%
A7MNR3 Cronobacter sakazakii (strain ATCC BAA-894) 29% 100%
A7MWD3 Vibrio campbellii (strain ATCC BAA-1116) 31% 100%
A7NC13 Francisella tularensis subsp. holarctica (strain FTNF002-00 / FTA) 25% 100%
A7ZSD0 Escherichia coli O139:H28 (strain E24377A / ETEC) 29% 100%
A8A545 Escherichia coli O9:H4 (strain HS) 29% 100%
A8AQC8 Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696) 30% 100%
A8FRU0 Shewanella sediminis (strain HAW-EB3) 31% 100%
A8G8Y7 Serratia proteamaculans (strain 568) 29% 100%
A8H0U0 Shewanella pealeana (strain ATCC 700345 / ANG-SQ1) 29% 100%
A8ILC6 Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571) 31% 100%
A9AMD5 Burkholderia multivorans (strain ATCC 17616 / 249) 50% 99%
A9BVK0 Delftia acidovorans (strain DSM 14801 / SPH-1) 49% 99%
A9EZV5 Sorangium cellulosum (strain So ce56) 28% 100%
A9IIS3 Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448) 50% 98%
A9KFT9 Coxiella burnetii (strain Dugway 5J108-111) 52% 99%
A9L340 Shewanella baltica (strain OS195) 29% 100%
A9MNX5 Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980) 30% 100%
A9N855 Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) 30% 100%
A9NDV1 Coxiella burnetii (strain RSA 331 / Henzerling II) 52% 99%
A9R584 Yersinia pestis bv. Antiqua (strain Angola) 29% 100%
A9W386 Methylorubrum extorquens (strain PA1) 28% 100%
B0B7U5 Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B) 41% 99%
B0BC10 Chlamydia trachomatis serovar L2b (strain UCH-1/proctitis) 41% 99%
B0BQN0 Actinobacillus pleuropneumoniae serotype 3 (strain JL03) 29% 100%
B0RU49 Xanthomonas campestris pv. campestris (strain B100) 50% 99%
B0SF41 Leptospira biflexa serovar Patoc (strain Patoc 1 / Ames) 50% 99%
B0SN74 Leptospira biflexa serovar Patoc (strain Patoc 1 / ATCC 23582 / Paris) 50% 99%
B0TUH8 Shewanella halifaxensis (strain HAW-EB4) 29% 100%
B0TZT2 Francisella philomiragia subsp. philomiragia (strain ATCC 25017 / FSC 153 / O#319-036) 26% 100%
B0U5Q1 Xylella fastidiosa (strain M12) 49% 99%
B0UCF0 Methylobacterium sp. (strain 4-46) 27% 100%
B0UUR6 Histophilus somni (strain 2336) 30% 100%
B0V6R7 Acinetobacter baumannii (strain AYE) 50% 99%
B0VQX5 Acinetobacter baumannii (strain SDF) 50% 99%
B1IQP3 Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks) 29% 100%
B1JMK1 Yersinia pseudotuberculosis serotype O:3 (strain YPIII) 29% 100%
B1K394 Burkholderia cenocepacia (strain MC0-3) 50% 99%
B1KGG7 Shewanella woodyi (strain ATCC 51908 / MS32) 30% 100%
B1LGK2 Escherichia coli (strain SMS-3-5 / SECEC) 29% 100%
B1LZN1 Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831 / NBRC 15690 / NCIMB 10815 / 0-1) 28% 100%
B1W3N4 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350) 50% 98%
B1XHK9 Escherichia coli (strain K12 / DH10B) 29% 100%
B1XV63 Polynucleobacter necessarius subsp. necessarius (strain STIR1) 49% 98%
B1Y8A3 Leptothrix cholodnii (strain ATCC 51168 / LMG 8142 / SP-6) 50% 99%
B1ZG93 Methylorubrum populi (strain ATCC BAA-705 / NCIMB 13946 / BJ001) 27% 100%
B2FQL8 Stenotrophomonas maltophilia (strain K279a) 50% 99%
B2GKC8 Kocuria rhizophila (strain ATCC 9341 / DSM 348 / NBRC 103217 / DC2201) 48% 99%
B2HRH5 Mycobacterium marinum (strain ATCC BAA-535 / M) 50% 98%
B2HZ52 Acinetobacter baumannii (strain ACICU) 50% 99%
B2I8M1 Xylella fastidiosa (strain M23) 50% 99%
B2JQD2 Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 / STM815) 49% 99%
B2K2N5 Yersinia pseudotuberculosis serotype IB (strain PB1/+) 29% 100%
B2SH29 Francisella tularensis subsp. mediasiatica (strain FSC147) 25% 100%
B2SMP6 Xanthomonas oryzae pv. oryzae (strain PXO99A) 50% 99%
B2T9P8 Paraburkholderia phytofirmans (strain DSM 17436 / LMG 22146 / PsJN) 49% 99%
B2U1U9 Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) 29% 100%
B2U705 Ralstonia pickettii (strain 12J) 50% 99%
B2UKY5 Akkermansia muciniphila (strain ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC 81048 / CCUG 64013 / CIP 107961 / Muc) 50% 98%
B2VGW7 Erwinia tasmaniensis (strain DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB 4357 / Et1/99) 28% 100%
B3H269 Actinobacillus pleuropneumoniae serotype 7 (strain AP76) 29% 100%
B3PHI3 Cellvibrio japonicus (strain Ueda107) 51% 99%
B3Q761 Rhodopseudomonas palustris (strain TIE-1) 28% 100%
B3QPY9 Chlorobaculum parvum (strain DSM 263 / NCIMB 8327) 28% 100%
B3R570 Cupriavidus taiwanensis (strain DSM 17343 / BCRC 17206 / CCUG 44338 / CIP 107171 / LMG 19424 / R1) 50% 99%
B4EFB0 Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610) 50% 99%
B4F2A1 Proteus mirabilis (strain HI4320) 31% 100%
B4SLI5 Stenotrophomonas maltophilia (strain R551-3) 49% 99%
B4T769 Salmonella newport (strain SL254) 30% 100%
B4TJT3 Salmonella heidelberg (strain SL476) 30% 100%
B4TWK9 Salmonella schwarzengrund (strain CVM19633) 30% 100%
B5BGR3 Salmonella paratyphi A (strain AKU_12601) 30% 100%
B5F7L9 Salmonella agona (strain SL483) 30% 100%
B5FGF5 Aliivibrio fischeri (strain MJ11) 30% 100%
B5FIT7 Salmonella dublin (strain CT_02021853) 29% 100%
B5R0N2 Salmonella enteritidis PT4 (strain P125109) 30% 100%
B5REV7 Salmonella gallinarum (strain 287/91 / NCTC 13346) 30% 100%
B5XSQ7 Klebsiella pneumoniae (strain 342) 31% 100%
B5YSW2 Escherichia coli O157:H7 (strain EC4115 / EHEC) 29% 100%
B6EL39 Aliivibrio salmonicida (strain LFI1238) 30% 100%
B6I1V4 Escherichia coli (strain SE11) 29% 100%
B6IYP5 Rhodospirillum centenum (strain ATCC 51521 / SW) 30% 100%
B6IZN7 Coxiella burnetii (strain CbuG_Q212) 52% 99%
B6J7Q0 Coxiella burnetii (strain CbuK_Q154) 52% 99%
B7GW58 Acinetobacter baumannii (strain AB307-0294) 50% 99%
B7I9D2 Acinetobacter baumannii (strain AB0057) 50% 99%
B7KVX2 Methylorubrum extorquens (strain CM4 / NCIMB 13688) 28% 100%
B7LHU4 Escherichia coli (strain 55989 / EAEC) 29% 100%
B7LRL0 Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73) 29% 100%
B7M0U8 Escherichia coli O8 (strain IAI1) 29% 100%
B7MBZ7 Escherichia coli O45:K1 (strain S88 / ExPEC) 29% 100%
B7N0M1 Escherichia coli O81 (strain ED1a) 29% 100%
B7NDL4 Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) 29% 100%
B7NKU9 Escherichia coli O7:K1 (strain IAI39 / ExPEC) 29% 100%
B7UJW8 Escherichia coli O127:H6 (strain E2348/69 / EPEC) 29% 100%
B7VID0 Vibrio atlanticus (strain LGP32) 30% 100%
B8CSY7 Shewanella piezotolerans (strain WP3 / JCM 13877) 30% 100%
B8EB55 Shewanella baltica (strain OS223) 29% 100%
B8F5K4 Glaesserella parasuis serovar 5 (strain SH0165) 31% 100%
B8GPC3 Thioalkalivibrio sulfidiphilus (strain HL-EbGR7) 25% 100%
B8GVT2 Caulobacter vibrioides (strain NA1000 / CB15N) 29% 100%
B8IJB4 Methylobacterium nodulans (strain LMG 21967 / CNCM I-2342 / ORS 2060) 27% 100%
B9DK67 Staphylococcus carnosus (strain TM300) 27% 100%
B9KIH0 Anaplasma marginale (strain Florida) 30% 100%
B9KNB4 Cereibacter sphaeroides (strain KD131 / KCTC 12085) 27% 100%
B9MBP0 Acidovorax ebreus (strain TPSY) 49% 99%
C0PZQ4 Salmonella paratyphi C (strain RKS4594) 30% 100%
C1AMN4 Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019) 51% 98%
C1B155 Rhodococcus opacus (strain B4) 48% 98%
C1CY73 Deinococcus deserti (strain DSM 17065 / CIP 109153 / LMG 22923 / VCD115) 53% 98%
C1DB66 Laribacter hongkongensis (strain HLHK9) 49% 98%
C4ZSX4 Escherichia coli (strain K12 / MC4100 / BW2952) 29% 100%
C5BF98 Edwardsiella ictaluri (strain 93-146) 29% 100%
C5BU70 Teredinibacter turnerae (strain ATCC 39867 / T7901) 50% 99%
C5CSI5 Variovorax paradoxus (strain S110) 48% 99%
C6DKH1 Pectobacterium carotovorum subsp. carotovorum (strain PC1) 30% 100%
D0A1U1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 26% 100%
D0A8Y7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 65% 99%
D9PVI7 Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg) 27% 100%
E9AS23 Leishmania mexicana (strain MHOM/GT/2001/U1103) 30% 100%
E9B0A8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 84% 100%
E9B4I1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 27% 100%
E9B4I2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 27% 98%
F1C7I4 Taenia solium 45% 98%
K0J107 Felis catus 27% 96%
O02640 Caenorhabditis elegans 27% 95%
O24047 Mesembryanthemum crystallinum 53% 98%
O26290 Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) 28% 100%
O48902 Medicago sativa 45% 74%
O48905 Medicago sativa 53% 98%
O82399 Arabidopsis thaliana 27% 92%
O84381 Chlamydia trachomatis (strain D/UW-3/Cx) 41% 99%
O88989 Rattus norvegicus 48% 97%
P0A5J7 Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) 51% 98%
P0C7R5 Yersinia pseudotuberculosis serotype I (strain IP32953) 29% 100%
P0C890 Prosthecochloris vibrioformis 28% 100%
P10584 Thermus thermophilus 50% 99%
P11708 Sus scrofa 48% 97%
P14152 Mus musculus 48% 97%
P15719 Zea mays 44% 75%
P17505 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 25% 97%
P17606 Sorghum bicolor 43% 76%
P17783 Citrullus lanatus 30% 93%
P19446 Citrullus lanatus 28% 91%
P21528 Pisum sativum 44% 73%
P22133 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 26% 86%
P25077 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 30% 100%
P32419 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 28% 94%
P37226 Photobacterium profundum (strain SS9) 32% 100%
P37229 Sorghum bicolor 42% 75%
P40925 Homo sapiens 48% 97%
P40926 Homo sapiens 28% 96%
P44427 Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) 28% 100%
P46488 Cucumis sativus 29% 91%
P46489 Flaveria bidentis 44% 72%
P48364 Moritella sp. (strain 5710) 29% 100%
P50917 Mycobacterium leprae (strain TN) 52% 98%
P52426 Spinacia oleracea 42% 74%
P57106 Arabidopsis thaliana 53% 98%
P61889 Escherichia coli (strain K12) 29% 100%
P61890 Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) 29% 100%
P61891 Escherichia coli O157:H7 29% 100%
P61892 Yersinia pestis 29% 100%
P61973 Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100) 49% 97%
P61974 Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis) 44% 99%
P61975 Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130) 48% 99%
P61976 Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10) 51% 98%
P61977 Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) 50% 99%
P80458 Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) 28% 100%
P80536 Burkholderia pseudomallei (strain K96243) 50% 99%
P82177 Shewanella oneidensis (strain MR-1) 30% 100%
P83373 Fragaria ananassa 29% 96%
P83778 Candida albicans (strain SC5314 / ATCC MYA-2876) 30% 96%
P93052 Botryococcus braunii 29% 100%
P93819 Arabidopsis thaliana 52% 98%
P9WK12 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) 51% 98%
P9WK13 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 51% 98%
Q04820 Echinococcus granulosus 45% 98%
Q04RS5 Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197) 48% 99%
Q05145 Mesembryanthemum crystallinum 42% 73%
Q051U6 Leptospira borgpetersenii serovar Hardjo-bovis (strain L550) 48% 99%
Q07UX5 Rhodopseudomonas palustris (strain BisA53) 27% 100%
Q07YA5 Shewanella frigidimarina (strain NCIMB 400) 30% 100%
Q08062 Zea mays 52% 98%
Q08BZ4 Danio rerio 24% 72%
Q0ABE6 Alkalilimnicola ehrlichii (strain ATCC BAA-1101 / DSM 17681 / MLHE-1) 48% 99%
Q0AFK6 Nitrosomonas eutropha (strain DSM 101675 / C91 / Nm57) 46% 99%
Q0AKT3 Maricaulis maris (strain MCS10) 29% 100%
Q0BAF9 Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) 50% 99%
Q0HEW2 Shewanella sp. (strain MR-4) 29% 100%
Q0HZ38 Shewanella sp. (strain MR-7) 29% 100%
Q0I491 Haemophilus somnus (strain 129Pt) 29% 100%
Q0K8F5 Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) 51% 99%
Q0RE66 Frankia alni (strain ACN14a) 50% 98%
Q0S365 Rhodococcus jostii (strain RHA1) 47% 98%
Q0T052 Shigella flexneri serotype 5b (strain 8401) 29% 100%
Q0TCN0 Escherichia coli O6:K15:H31 (strain 536 / UPEC) 29% 100%
Q0VQ52 Alcanivorax borkumensis (strain ATCC 700651 / DSM 11573 / NCIMB 13689 / SK2) 51% 99%
Q11CV9 Chelativorans sp. (strain BNC1) 26% 100%
Q126N9 Polaromonas sp. (strain JS666 / ATCC BAA-500) 47% 99%
Q12R11 Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013) 29% 100%
Q13DR6 Rhodopseudomonas palustris (strain BisB5) 29% 100%
Q13S42 Paraburkholderia xenovorans (strain LB400) 50% 99%
Q14IT0 Francisella tularensis subsp. tularensis (strain FSC 198) 25% 100%
Q15YH0 Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087) 29% 100%
Q1AWH4 Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129 / PRD-1) 50% 100%
Q1BM38 Burkholderia cenocepacia (strain AU 1054) 50% 99%
Q1CBY7 Yersinia pestis bv. Antiqua (strain Antiqua) 29% 100%
Q1CEJ3 Yersinia pestis bv. Antiqua (strain Nepal516) 29% 100%
Q1IWC9 Deinococcus geothermalis (strain DSM 11300 / AG-3a) 54% 97%
Q1LKG0 Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34) 50% 99%
Q1Q932 Psychrobacter cryohalolentis (strain ATCC BAA-1226 / DSM 17306 / VKM B-2378 / K5) 51% 98%
Q1QQR2 Nitrobacter hamburgensis (strain DSM 10229 / NCIMB 13809 / X14) 28% 100%
Q1R6A3 Escherichia coli (strain UTI89 / UPEC) 29% 100%
Q21K60 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) 50% 99%
Q21VT3 Albidiferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118) 44% 97%
Q21XH1 Albidiferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118) 47% 99%
Q255I4 Chlamydia felis (strain Fe/C-56) 40% 99%
Q2A3K7 Francisella tularensis subsp. holarctica (strain LVS) 25% 100%
Q2G946 Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CCUG 56034 / CIP 105152 / NBRC 16084 / F199) 28% 100%
Q2GCH6 Neorickettsia sennetsu (strain ATCC VR-367 / Miyayama) 28% 100%
Q2J3G8 Rhodopseudomonas palustris (strain HaA2) 29% 100%
Q2J7E7 Frankia casuarinae (strain DSM 45818 / CECT 9043 / CcI3) 49% 98%
Q2L068 Bordetella avium (strain 197N) 49% 98%
Q2NGI3 Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3) 26% 100%
Q2P736 Xanthomonas oryzae pv. oryzae (strain MAFF 311018) 50% 99%
Q2RV34 Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1) 26% 100%
Q2T4T8 Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264) 45% 98%
Q2T7J2 Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264) 50% 99%
Q2W064 Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) 25% 100%
Q2YAQ4 Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71) 48% 99%
Q30RQ5 Sulfurimonas denitrificans (strain ATCC 33889 / DSM 1251) 28% 100%
Q31WA4 Shigella boydii serotype 4 (strain Sb227) 29% 100%
Q32BA3 Shigella dysenteriae serotype 1 (strain Sd197) 29% 100%
Q393V1 Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383) 50% 99%
Q3BWU8 Xanthomonas campestris pv. vesicatoria (strain 85-10) 51% 99%
Q3IFH4 Pseudoalteromonas translucida (strain TAC 125) 31% 100%
Q3IZ83 Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) 27% 100%
Q3JKE9 Burkholderia pseudomallei (strain 1710b) 50% 99%
Q3KLX8 Chlamydia trachomatis serovar A (strain ATCC VR-571B / DSM 19440 / HAR-13) 41% 99%
Q3MDN9 Trichormus variabilis (strain ATCC 29413 / PCC 7937) 29% 100%
Q3T145 Bos taurus 47% 97%
Q3YX11 Shigella sonnei (strain Ss046) 29% 100%
Q42686 Chlamydomonas reinhardtii 27% 87%
Q42972 Oryza sativa subsp. japonica 28% 91%
Q43744 Brassica napus 30% 95%
Q46YU4 Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) 51% 99%
Q47C34 Dechloromonas aromatica (strain RCB) 45% 99%
Q47TT4 Thermobifida fusca (strain YX) 52% 98%
Q47VL0 Colwellia psychrerythraea (strain 34H / ATCC BAA-681) 28% 100%
Q4FQU7 Psychrobacter arcticus (strain DSM 17307 / VKM B-2377 / 273-4) 51% 98%
Q4JWV0 Corynebacterium jeikeium (strain K411) 49% 98%
Q4Q3J3 Leishmania major 26% 100%
Q4Q7X6 Leishmania major 85% 100%
Q4QDF0 Leishmania major 30% 100%
Q4QL89 Haemophilus influenzae (strain 86-028NP) 28% 100%
Q4R568 Macaca fascicularis 27% 96%
Q4URH2 Xanthomonas campestris pv. campestris (strain 8004) 50% 99%
Q54D04 Dictyostelium discoideum 46% 93%
Q54GE6 Dictyostelium discoideum 51% 83%
Q54VM2 Dictyostelium discoideum 49% 97%
Q57JA9 Salmonella choleraesuis (strain SC-B67) 30% 100%
Q59838 Salmonella muenchen 28% 100%
Q5E875 Aliivibrio fischeri (strain ATCC 700601 / ES114) 30% 100%
Q5GT41 Wolbachia sp. subsp. Brugia malayi (strain TRS) 27% 100%
Q5H496 Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85) 50% 99%
Q5L5E3 Chlamydia abortus (strain DSM 27085 / S26/3) 40% 98%
Q5NYA9 Aromatoleum aromaticum (strain EbN1) 46% 98%
Q5PAV3 Anaplasma marginale (strain St. Maries) 31% 100%
Q5R030 Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR) 29% 100%
Q5SKV7 Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) 50% 99%
Q5U907 Actinobacillus succinogenes (strain ATCC 55618 / DSM 22257 / CCUG 43843 / 130Z) 26% 100%
Q5WU94 Legionella pneumophila (strain Lens) 49% 98%
Q5X2T6 Legionella pneumophila (strain Paris) 49% 98%
Q5YTI1 Nocardia farcinica (strain IFM 10152) 50% 97%
Q5ZME2 Gallus gallus 50% 97%
Q5ZT13 Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513) 49% 98%
Q60176 Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) 29% 100%
Q60B71 Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath) 47% 100%
Q62AG8 Burkholderia mallei (strain ATCC 23344) 50% 99%
Q6A6Z5 Cutibacterium acnes (strain DSM 16379 / KPA171202) 50% 99%
Q6AQI3 Desulfotalea psychrophila (strain LSv54 / DSM 12343) 47% 100%
Q6AW21 Moritella japonica 29% 100%
Q6AW23 Moritella marina 29% 100%
Q6D9D1 Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) 30% 100%
Q6DIY9 Xenopus tropicalis 48% 97%
Q6F7X1 Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) 49% 99%
Q6FYD0 Bartonella quintana (strain Toulouse) 27% 100%
Q6LZI3 Methanococcus maripaludis (strain S2 / LL) 25% 100%
Q6MAA3 Protochlamydia amoebophila (strain UWE25) 45% 98%
Q6PAB3 Xenopus laevis 48% 97%
Q7MP97 Vibrio vulnificus (strain YJ016) 31% 100%
Q7MYW9 Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01) 29% 100%
Q7NZ60 Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757) 50% 99%
Q7VP41 Haemophilus ducreyi (strain 35000HP / ATCC 700724) 27% 100%
Q7VW97 Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) 49% 98%
Q7W5Q8 Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253) 49% 98%
Q7WD94 Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50) 49% 98%
Q7WS85 Salmonella paratyphi A (strain ATCC 9150 / SARB42) 30% 100%
Q7XDC8 Oryza sativa subsp. japonica 50% 98%
Q7YRU4 Felis catus 48% 97%
Q822E9 Chlamydia caviae (strain ATCC VR-813 / DSM 19441 / 03DC25 / GPIC) 41% 98%
Q82HS2 Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680) 50% 98%
Q82WB9 Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298) 48% 99%
Q83C87 Coxiella burnetii (strain RSA 493 / Nine Mile phase I) 52% 99%
Q83Q04 Shigella flexneri 29% 100%
Q84FY8 Methylorubrum extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1) 28% 100%
Q87E35 Xylella fastidiosa (strain Temecula1 / ATCC 700964) 50% 99%
Q87SU7 Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) 32% 100%
Q89X59 Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110) 28% 100%
Q8DEC2 Vibrio vulnificus (strain CMCP6) 31% 100%
Q8F4A2 Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601) 48% 99%
Q8FN62 Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395) 45% 100%
Q8GNM0 Francisella novicida 25% 100%
Q8H1E2 Arabidopsis thaliana 44% 73%
Q8NN33 Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) 45% 99%
Q8PC25 Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) 50% 99%
Q8PNP8 Xanthomonas axonopodis pv. citri (strain 306) 50% 99%
Q8PVJ7 Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) 26% 100%
Q8TWG5 Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938) 31% 100%
Q8XXW5 Ralstonia solanacearum (strain GMI1000) 50% 98%
Q8YP78 Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) 27% 100%
Q8Z3E0 Salmonella typhi 30% 100%
Q9A2B1 Caulobacter vibrioides (strain ATCC 19089 / CB15) 29% 100%
Q9CN86 Pasteurella multocida (strain Pm70) 29% 100%
Q9FJU0 Arabidopsis thaliana 49% 96%
Q9FSF0 Nicotiana tabacum 52% 98%
Q9K3J3 Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) 50% 98%
Q9KUT3 Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) 32% 100%
Q9L8F6 Vibrio mimicus 30% 100%
Q9PE17 Xylella fastidiosa (strain 9a5c) 49% 99%
Q9PK18 Chlamydia muridarum (strain MoPn / Nigg) 41% 99%
Q9RXI8 Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422) 53% 98%
Q9SML8 Beta vulgaris 52% 98%
Q9SN86 Arabidopsis thaliana 29% 80%
Q9UAV5 Caenorhabditis elegans 52% 96%
Q9Z6N1 Chlamydia pneumoniae 41% 99%
Q9ZF99 Aquaspirillum arcticum 50% 98%
Q9ZP06 Arabidopsis thaliana 30% 95%
V5BI57 Trypanosoma cruzi 57% 98%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS