Myb-like domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HGV1_LEIBR

TriTrypDb:

LbrM.28.2690 , LBRM2903_280033800

Length:

513

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HGV1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HGV1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	122	126	PF00656	0.616
CLV_C14_Caspase3-7	178	182	PF00656	0.540
CLV_C14_Caspase3-7	276	280	PF00656	0.628
CLV_C14_Caspase3-7	328	332	PF00656	0.744
CLV_C14_Caspase3-7	64	68	PF00656	0.626
CLV_NRD_NRD_1	193	195	PF00675	0.579
CLV_NRD_NRD_1	206	208	PF00675	0.597
CLV_NRD_NRD_1	21	23	PF00675	0.591
CLV_NRD_NRD_1	487	489	PF00675	0.400
CLV_NRD_NRD_1	52	54	PF00675	0.578
CLV_PCSK_FUR_1	206	210	PF00082	0.584
CLV_PCSK_KEX2_1	193	195	PF00082	0.579
CLV_PCSK_KEX2_1	206	208	PF00082	0.578
CLV_PCSK_KEX2_1	21	23	PF00082	0.591
CLV_PCSK_KEX2_1	487	489	PF00082	0.400
CLV_PCSK_KEX2_1	52	54	PF00082	0.578
CLV_PCSK_PC1ET2_1	208	210	PF00082	0.584
CLV_PCSK_SKI1_1	318	322	PF00082	0.576
CLV_PCSK_SKI1_1	462	466	PF00082	0.395
CLV_PCSK_SKI1_1	55	59	PF00082	0.562
DEG_APCC_DBOX_1	317	325	PF00400	0.516
DEG_Nend_UBRbox_2	1	3	PF02207	0.554
DOC_CYCLIN_RxL_1	456	469	PF00134	0.399
DOC_MAPK_gen_1	306	315	PF00069	0.609
DOC_MAPK_gen_1	498	506	PF00069	0.482
DOC_MAPK_gen_1	52	59	PF00069	0.561
DOC_PP1_RVXF_1	130	136	PF00149	0.495
DOC_PP4_FxxP_1	37	40	PF00568	0.525
DOC_USP7_MATH_1	119	123	PF00917	0.674
DOC_USP7_MATH_1	174	178	PF00917	0.625
DOC_USP7_MATH_1	234	238	PF00917	0.715
DOC_USP7_MATH_1	245	249	PF00917	0.688
DOC_USP7_MATH_1	250	254	PF00917	0.620
DOC_USP7_MATH_1	387	391	PF00917	0.527
DOC_USP7_MATH_1	43	47	PF00917	0.519
DOC_USP7_MATH_1	448	452	PF00917	0.366
DOC_USP7_MATH_1	77	81	PF00917	0.510
DOC_WW_Pin1_4	181	186	PF00397	0.605
DOC_WW_Pin1_4	210	215	PF00397	0.698
DOC_WW_Pin1_4	246	251	PF00397	0.678
DOC_WW_Pin1_4	28	33	PF00397	0.562
DOC_WW_Pin1_4	337	342	PF00397	0.547
DOC_WW_Pin1_4	38	43	PF00397	0.742
DOC_WW_Pin1_4	471	476	PF00397	0.501
DOC_WW_Pin1_4	499	504	PF00397	0.489
LIG_14-3-3_CanoR_1	132	136	PF00244	0.497
LIG_14-3-3_CanoR_1	22	28	PF00244	0.521
LIG_14-3-3_CanoR_1	456	465	PF00244	0.305
LIG_14-3-3_CanoR_1	491	497	PF00244	0.338
LIG_APCC_ABBA_1	57	62	PF00400	0.573
LIG_BRCT_BRCA1_1	147	151	PF00533	0.594
LIG_CaM_IQ_9	476	492	PF13499	0.406
LIG_deltaCOP1_diTrp_1	406	413	PF00928	0.586
LIG_FHA_1	110	116	PF00498	0.671
LIG_FHA_1	119	125	PF00498	0.636
LIG_FHA_1	467	473	PF00498	0.520
LIG_FHA_1	52	58	PF00498	0.560
LIG_FHA_2	312	318	PF00498	0.553
LIG_FHA_2	349	355	PF00498	0.578
LIG_FHA_2	76	82	PF00498	0.534
LIG_FXI_DFP_1	410	414	PF00024	0.651
LIG_HCF-1_HBM_1	365	368	PF13415	0.531
LIG_LIR_Apic_2	35	40	PF02991	0.524
LIG_LIR_Apic_2	365	371	PF02991	0.527
LIG_LIR_Gen_1	406	413	PF02991	0.572
LIG_LIR_Nem_3	290	295	PF02991	0.630
LIG_LIR_Nem_3	406	411	PF02991	0.594
LIG_PDZ_Class_1	508	513	PF00595	0.570
LIG_Rb_LxCxE_1	435	453	PF01857	0.374
LIG_SH2_CRK	368	372	PF00017	0.528
LIG_SH2_CRK	493	497	PF00017	0.428
LIG_SH2_STAP1	311	315	PF00017	0.616
LIG_SH3_3	159	165	PF00018	0.608
LIG_SH3_3	217	223	PF00018	0.546
LIG_SH3_3	257	263	PF00018	0.605
LIG_SH3_3	39	45	PF00018	0.664
LIG_SH3_3	469	475	PF00018	0.508
LIG_SH3_3	493	499	PF00018	0.352
LIG_SUMO_SIM_anti_2	426	432	PF11976	0.343
LIG_SUMO_SIM_par_1	429	435	PF11976	0.396
LIG_SUMO_SIM_par_1	501	507	PF11976	0.564
LIG_TRAF2_1	134	137	PF00917	0.581
LIG_TRAF2_1	351	354	PF00917	0.552
LIG_UBA3_1	464	470	PF00899	0.313
LIG_WW_3	49	53	PF00397	0.643
MOD_CK1_1	253	259	PF00069	0.816
MOD_CK1_1	26	32	PF00069	0.665
MOD_CK1_1	270	276	PF00069	0.539
MOD_CK1_1	340	346	PF00069	0.536
MOD_CK1_1	38	44	PF00069	0.599
MOD_CK2_1	131	137	PF00069	0.580
MOD_CK2_1	181	187	PF00069	0.547
MOD_CK2_1	224	230	PF00069	0.603
MOD_CK2_1	311	317	PF00069	0.546
MOD_CK2_1	348	354	PF00069	0.553
MOD_CK2_1	471	477	PF00069	0.500
MOD_CK2_1	75	81	PF00069	0.519
MOD_GlcNHglycan	140	143	PF01048	0.584
MOD_GlcNHglycan	147	150	PF01048	0.609
MOD_GlcNHglycan	177	180	PF01048	0.608
MOD_GlcNHglycan	215	218	PF01048	0.650
MOD_GlcNHglycan	226	229	PF01048	0.690
MOD_GlcNHglycan	236	239	PF01048	0.674
MOD_GlcNHglycan	240	243	PF01048	0.668
MOD_GlcNHglycan	269	272	PF01048	0.579
MOD_GlcNHglycan	342	345	PF01048	0.542
MOD_GlcNHglycan	346	349	PF01048	0.540
MOD_GlcNHglycan	37	40	PF01048	0.633
MOD_GlcNHglycan	381	384	PF01048	0.679
MOD_GlcNHglycan	45	48	PF01048	0.543
MOD_GlcNHglycan	450	453	PF01048	0.339
MOD_GlcNHglycan	458	461	PF01048	0.291
MOD_GlcNHglycan	81	84	PF01048	0.658
MOD_GlcNHglycan	96	99	PF01048	0.526
MOD_GSK3_1	109	116	PF00069	0.678
MOD_GSK3_1	23	30	PF00069	0.642
MOD_GSK3_1	234	241	PF00069	0.717
MOD_GSK3_1	246	253	PF00069	0.655
MOD_GSK3_1	336	343	PF00069	0.549
MOD_GSK3_1	344	351	PF00069	0.528
MOD_GSK3_1	75	82	PF00069	0.631
MOD_NEK2_1	202	207	PF00069	0.510
MOD_NEK2_1	27	32	PF00069	0.599
MOD_PKA_2	131	137	PF00069	0.497
MOD_PKA_2	51	57	PF00069	0.598
MOD_Plk_1	311	317	PF00069	0.627
MOD_Plk_1	406	412	PF00069	0.511
MOD_Plk_2-3	277	283	PF00069	0.524
MOD_Plk_4	119	125	PF00069	0.675
MOD_Plk_4	23	29	PF00069	0.534
MOD_Plk_4	492	498	PF00069	0.508
MOD_ProDKin_1	181	187	PF00069	0.603
MOD_ProDKin_1	210	216	PF00069	0.700
MOD_ProDKin_1	246	252	PF00069	0.679
MOD_ProDKin_1	28	34	PF00069	0.563
MOD_ProDKin_1	337	343	PF00069	0.549
MOD_ProDKin_1	38	44	PF00069	0.741
MOD_ProDKin_1	471	477	PF00069	0.500
MOD_ProDKin_1	499	505	PF00069	0.487
MOD_SUMO_rev_2	322	332	PF00179	0.535
TRG_DiLeu_BaEn_2	452	458	PF01217	0.412
TRG_DiLeu_BaEn_4	406	412	PF01217	0.560
TRG_DiLeu_BaEn_4	420	426	PF01217	0.585
TRG_DiLeu_BaLyEn_6	460	465	PF01217	0.383
TRG_DiLeu_LyEn_5	187	192	PF01217	0.510
TRG_ENDOCYTIC_2	493	496	PF00928	0.426
TRG_ER_diArg_1	157	160	PF00400	0.656
TRG_ER_diArg_1	192	194	PF00400	0.584
TRG_ER_diArg_1	206	209	PF00400	0.580
TRG_ER_diArg_1	305	308	PF00400	0.621
TRG_ER_diArg_1	486	488	PF00400	0.402
TRG_ER_diArg_1	497	500	PF00400	0.469
TRG_ER_diArg_1	51	53	PF00400	0.645
TRG_NLS_Bipartite_1	193	211	PF00514	0.578
TRG_NLS_MonoExtC_3	206	211	PF00514	0.588
TRG_NLS_MonoExtN_4	206	211	PF00514	0.588
TRG_Pf-PMV_PEXEL_1	318	322	PF00026	0.557
TRG_Pf-PMV_PEXEL_1	462	466	PF00026	0.475

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PA28	Leptomonas seymouri	42%	100%
A0A3S5H7K0	Leishmania donovani	64%	99%
A4I3Y1	Leishmania infantum	64%	99%
E9B071	Leishmania mexicana (strain MHOM/GT/2001/U1103)	65%	100%
Q4Q814	Leishmania major	65%	98%