DUF676 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Putative serine esterase (DUF676), putative

Species:

Leishmania braziliensis

UniProt:

A4HGU8_LEIBR

TriTrypDb:

LbrM.28.2650 , LBRM2903_280033200

Length:

399

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HGU8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HGU8

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	290	294	PF00656	0.518
CLV_C14_Caspase3-7	380	384	PF00656	0.560
CLV_NRD_NRD_1	161	163	PF00675	0.393
CLV_NRD_NRD_1	54	56	PF00675	0.388
CLV_PCSK_FUR_1	158	162	PF00082	0.427
CLV_PCSK_KEX2_1	160	162	PF00082	0.362
CLV_PCSK_KEX2_1	188	190	PF00082	0.569
CLV_PCSK_KEX2_1	54	56	PF00082	0.388
CLV_PCSK_PC1ET2_1	160	162	PF00082	0.347
CLV_PCSK_PC1ET2_1	188	190	PF00082	0.440

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3P6	Leptomonas seymouri	44%	86%
A0A1X0NR47	Trypanosomatidae	31%	100%
A0A3Q8IQU6	Leishmania donovani	55%	82%
A0A3R7K6Z5	Trypanosoma rangeli	30%	100%
A4I3X6	Leishmania infantum	56%	82%
D0A944	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	100%
E9B066	Leishmania mexicana (strain MHOM/GT/2001/U1103)	51%	81%

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