LeishMANIAdb
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Anaphase-promoting complex subunit 13

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Anaphase-promoting complex subunit 13
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HGK4_LEIBR
TriTrypDb:
LbrM.28.1680 , LBRM2903_280022900
Length:
166

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HGK4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HGK4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_MEL_PAP_1 141 147 PF00089 0.473
CLV_NRD_NRD_1 139 141 PF00675 0.595
CLV_NRD_NRD_1 161 163 PF00675 0.593
CLV_NRD_NRD_1 77 79 PF00675 0.578
CLV_PCSK_KEX2_1 139 141 PF00082 0.631
CLV_PCSK_KEX2_1 77 79 PF00082 0.578
DEG_SPOP_SBC_1 14 18 PF00917 0.582
DEG_SPOP_SBC_1 92 96 PF00917 0.537
DOC_PP2B_LxvP_1 79 82 PF13499 0.510
DOC_USP7_MATH_1 108 112 PF00917 0.496
DOC_USP7_MATH_1 14 18 PF00917 0.688
DOC_USP7_MATH_1 82 86 PF00917 0.625
DOC_USP7_MATH_1 90 94 PF00917 0.523
LIG_14-3-3_CanoR_1 77 82 PF00244 0.507
LIG_BIR_II_1 1 5 PF00653 0.670
LIG_FHA_1 40 46 PF00498 0.536
LIG_TRAF2_1 121 124 PF00917 0.563
MOD_CK1_1 15 21 PF00069 0.604
MOD_CK1_1 73 79 PF00069 0.571
MOD_CK1_1 93 99 PF00069 0.562
MOD_CK2_1 118 124 PF00069 0.562
MOD_CK2_1 150 156 PF00069 0.634
MOD_CK2_1 38 44 PF00069 0.593
MOD_GlcNHglycan 60 63 PF01048 0.794
MOD_GlcNHglycan 72 75 PF01048 0.536
MOD_GlcNHglycan 79 82 PF01048 0.475
MOD_GlcNHglycan 98 101 PF01048 0.559
MOD_GSK3_1 104 111 PF00069 0.536
MOD_GSK3_1 13 20 PF00069 0.658
MOD_GSK3_1 150 157 PF00069 0.684
MOD_GSK3_1 73 80 PF00069 0.572
MOD_GSK3_1 90 97 PF00069 0.583
MOD_N-GLC_1 65 70 PF02516 0.651
MOD_NEK2_1 65 70 PF00069 0.511
MOD_PKA_1 77 83 PF00069 0.579
MOD_PKA_2 70 76 PF00069 0.588
MOD_PKA_2 77 83 PF00069 0.579
MOD_Plk_1 154 160 PF00069 0.607
MOD_Plk_2-3 150 156 PF00069 0.634
MOD_Plk_2-3 39 45 PF00069 0.608
TRG_ER_diArg_1 138 140 PF00400 0.603
TRG_ER_diArg_1 77 79 PF00400 0.579
TRG_Pf-PMV_PEXEL_1 139 143 PF00026 0.600

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IIA3 Leptomonas seymouri 41% 100%
A0A3S7X1K8 Leishmania donovani 70% 100%
A4I3N0 Leishmania infantum 70% 100%
E9AZX1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 68% 100%
Q4Q8B4 Leishmania major 67% 95%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS